Published in Circulation on July 30, 2007
Habitual exercise and arterial aging. J Appl Physiol (1985) (2008) 2.19
Aging is associated with greater nuclear NF kappa B, reduced I kappa B alpha, and increased expression of proinflammatory cytokines in vascular endothelial cells of healthy humans. Aging Cell (2008) 1.89
Short communication: vascular smooth muscle cell stiffness as a mechanism for increased aortic stiffness with aging. Circ Res (2010) 1.56
Arterial stiffening with ageing is associated with transforming growth factor-β1-related changes in adventitial collagen: reversal by aerobic exercise. J Physiol (2010) 1.51
Superoxide-lowering therapy with TEMPOL reverses arterial dysfunction with aging in mice. Aging Cell (2012) 1.29
Estrogen, aging and the cardiovascular system. Future Cardiol (2009) 1.09
Localised micro-mechanical stiffening in the ageing aorta. Mech Ageing Dev (2011) 1.02
Temporal analysis of vascular smooth muscle cell elasticity and adhesion reveals oscillation waveforms that differ with aging. Aging Cell (2012) 0.99
Curcumin ameliorates arterial dysfunction and oxidative stress with aging. Exp Gerontol (2012) 0.98
Role of aging versus the loss of estrogens in the reduction in vascular function in female rats. Endocrinology (2008) 0.98
Mechanism of diastolic stiffening of the failing myocardium and its prevention by angiotensin receptor and calcium channel blockers. J Cardiovasc Pharmacol (2009) 0.94
Preferential secretion of collagen type 3 versus type 1 from adventitial fibroblasts stimulated by TGF-β/Smad3-treated medial smooth muscle cells. Cell Signal (2012) 0.93
Increased apoptosis and myocyte enlargement with decreased cardiac mass; distinctive features of the aging male, but not female, monkey heart. J Mol Cell Cardiol (2007) 0.92
Characterization of a novel cardiac isoform of the cell cycle-related kinase that is regulated during heart failure. J Biol Chem (2008) 0.90
"Smooth Muscle Cell Stiffness Syndrome"-Revisiting the Structural Basis of Arterial Stiffness. Front Physiol (2015) 0.88
Age-related changes in the contractile and passive arterial properties of murine mesenteric small arteries are altered by caveolin-1 knockout. J Cell Mol Med (2012) 0.87
Type VIII collagen mediates vessel wall remodeling after arterial injury and fibrous cap formation in atherosclerosis. Am J Pathol (2013) 0.84
Large elastic artery stiffness with aging: novel translational mechanisms and interventions. Aging Dis (2012) 0.81
Halofuginone stimulates adaptive remodeling and preserves re-endothelialization in balloon-injured rat carotid arteries. Circ Cardiovasc Interv (2014) 0.79
Relation of murine thoracic aortic structural and cellular changes with aging to passive and active mechanical properties. J Am Heart Assoc (2015) 0.78
Pulse wave velocity and age- and gender-dependent aortic wall hardening in fowl. Comp Biochem Physiol A Mol Integr Physiol (2009) 0.78
Inhibition of SRF/myocardin reduces aortic stiffness by targeting vascular smooth muscle cell stiffening in hypertension. Cardiovasc Res (2016) 0.78
Extracellular Matrix Disarray as a Mechanism for Greater Abdominal Versus Thoracic Aortic Stiffness With Aging in Primates. Arterioscler Thromb Vasc Biol (2016) 0.76
Contributions of Nonhuman Primates to Research on Aging. Vet Pathol (2016) 0.76
Cardiovascular function, compliance, and connective tissue remodeling in the turtle, Trachemys scripta, following thermal acclimation. Am J Physiol Regul Integr Comp Physiol (2016) 0.75
Sex differences in myocardial infarction and rupture. J Mol Cell Cardiol (2007) 0.75
Segmental arterial stiffness in relation to B-type natriuretic peptide with preserved systolic heart function. PLoS One (2017) 0.75
Resistance training improves aortic structure in Wistar rats. Braz J Phys Ther (2017) 0.75
Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ Res (2007) 5.23
Cardiac myosin activation: a potential therapeutic approach for systolic heart failure. Science (2011) 4.36
Autophagy in chronically ischemic myocardium. Proc Natl Acad Sci U S A (2005) 3.55
Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes. Circ Res (2009) 3.53
Type 5 adenylyl cyclase disruption increases longevity and protects against stress. Cell (2007) 2.96
Low-molecular-weight heparin versus compression stockings for thromboprophylaxis after knee arthroscopy: a randomized trial. Ann Intern Med (2008) 2.85
Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes. Circ Res (2004) 2.82
Activation of the cardiac proteasome during pressure overload promotes ventricular hypertrophy. Circulation (2006) 2.50
A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy. Cell (2008) 2.47
Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy. J Clin Invest (2003) 2.20
Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophy. J Clin Invest (2003) 2.19
Repetitive ischemia by coronary stenosis induces a novel window of ischemic preconditioning. Circulation (2008) 2.09
The potential for cost savings through bundled episode payments. N Engl J Med (2012) 2.02
Direct effects of glucagon-like peptide-1 on myocardial contractility and glucose uptake in normal and postischemic isolated rat hearts. J Pharmacol Exp Ther (2006) 1.98
Disruption of type 5 adenylyl cyclase gene preserves cardiac function against pressure overload. Proc Natl Acad Sci U S A (2003) 1.64
Linkage disequilibrium mapping of quantitative-trait Loci by selective genotyping. Am J Hum Genet (2005) 1.64
Endocytosis machinery is required for beta1-adrenergic receptor-induced hypertrophy in neonatal rat cardiac myocytes. Cardiovasc Res (2008) 1.59
Active metabolite of GLP-1 mediates myocardial glucose uptake and improves left ventricular performance in conscious dogs with dilated cardiomyopathy. Am J Physiol Heart Circ Physiol (2005) 1.58
Improvement of cardiac function by a cardiac Myosin activator in conscious dogs with systolic heart failure. Circ Heart Fail (2010) 1.57
Short communication: vascular smooth muscle cell stiffness as a mechanism for increased aortic stiffness with aging. Circ Res (2010) 1.56
The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy. J Clin Invest (2002) 1.56
Second window of preconditioning normalizes palmitate use for oxidation and improves function during low-flow ischaemia. Cardiovasc Res (2011) 1.49
Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus. Circ Res (2005) 1.48
Mechanism of enhanced cardiac function in mice with hypertrophy induced by overexpressed Akt. J Biol Chem (2003) 1.47
Molecular mechanisms and physiological significance of autophagy during myocardial ischemia and reperfusion. Autophagy (2008) 1.46
Cardiac-specific overexpression of AT1 receptor mutant lacking G alpha q/G alpha i coupling causes hypertrophy and bradycardia in transgenic mice. J Clin Invest (2005) 1.45
Comparison of clinical features and hematologic abnormalities between dengue fever and dengue hemorrhagic fever among children in the Philippines. Am J Trop Med Hyg (2005) 1.45
Cardiac nerves affect myocardial stunning through reactive oxygen and nitric oxide mechanisms. Circ Res (2003) 1.45
A new method of predicting US and state-level cancer mortality counts for the current calendar year. CA Cancer J Clin (2004) 1.42
Aging increases aortic MMP-2 activity and angiotensin II in nonhuman primates. Hypertension (2003) 1.41
Disruption of type 5 adenylyl cyclase enhances desensitization of cyclic adenosine monophosphate signal and increases Akt signal with chronic catecholamine stress. Circulation (2007) 1.37
The development of myocardial insulin resistance in conscious dogs with advanced dilated cardiomyopathy. Cardiovasc Res (2004) 1.35
Downregulation of metabolic gene expression in failing human heart before and after mechanical unloading. Cardiology (2002) 1.33
Motor dysfunction in type 5 adenylyl cyclase-null mice. J Biol Chem (2003) 1.32
Paradoxical cellular Ca2+ signaling in severe but compensated canine left ventricular hypertrophy. Circ Res (2005) 1.29
Program of cell survival underlying human and experimental hibernating myocardium. Circ Res (2004) 1.27
Echocardiography in Mice. Curr Protoc Mouse Biol (2011) 1.27
Type 5 adenylyl cyclase disruption alters not only sympathetic but also parasympathetic and calcium-mediated cardiac regulation. Circ Res (2003) 1.25
Glucagon-like peptide-1 limits myocardial stunning following brief coronary occlusion and reperfusion in conscious canines. J Pharmacol Exp Ther (2004) 1.25
Modulation of beta-adrenergic receptor signaling in heart failure and longevity: targeting adenylyl cyclase type 5. Heart Fail Rev (2010) 1.24
Proteasome inhibition decreases cardiac remodeling after initiation of pressure overload. Am J Physiol Heart Circ Physiol (2008) 1.23
Sex-specific regulation of gene expression in the aging monkey aorta. Physiol Genomics (2007) 1.23
Molecular epidemiology of dengue 2 viruses in the Philippines: genotype shift and local evolution. Am J Trop Med Hyg (2005) 1.22
Aging increases stiffness of cardiac myocytes measured by atomic force microscopy nanoindentation. Am J Physiol Heart Circ Physiol (2004) 1.19
H11 kinase prevents myocardial infarction by preemptive preconditioning of the heart. Circ Res (2005) 1.19
Inhibition of p38 alpha MAPK rescues cardiomyopathy induced by overexpressed beta 2-adrenergic receptor, but not beta 1-adrenergic receptor. J Clin Invest (2007) 1.17
Adenylyl cyclase type 5 protein expression during cardiac development and stress. Am J Physiol Heart Circ Physiol (2009) 1.16
Is treating cardiac hypertrophy salutary or detrimental: the two faces of Janus. Am J Physiol Heart Circ Physiol (2003) 1.15
Increased vascular smooth muscle cell stiffness: a novel mechanism for aortic stiffness in hypertension. Am J Physiol Heart Circ Physiol (2013) 1.14
Predicting US- and state-level cancer counts for the current calendar year: Part II: evaluation of spatiotemporal projection methods for incidence. Cancer (2012) 1.14
Dengue illness: clinical features and pathogenesis. J Infect Chemother (2007) 1.12
FGF induces hypertrophy and angiogenesis in hibernating myocardium. Circ Res (2005) 1.11
Glucagon-like peptide-1 increases myocardial glucose uptake via p38alpha MAP kinase-mediated, nitric oxide-dependent mechanisms in conscious dogs with dilated cardiomyopathy. Circ Heart Fail (2010) 1.11
Common genomic response in different mouse models of beta-adrenergic-induced cardiomyopathy. Circulation (2003) 1.10
Proteasome inhibitors and cardiac cell growth. Cardiovasc Res (2009) 1.10
H11 kinase is a novel mediator of myocardial hypertrophy in vivo. Circ Res (2002) 1.09
H11 kinase/heat shock protein 22 deletion impairs both nuclear and mitochondrial functions of STAT3 and accelerates the transition into heart failure on cardiac overload. Circulation (2011) 1.09
Caloric restriction reduces growth of mammary tumors and metastases. Carcinogenesis (2011) 1.09