Keiran Raine

Author PubWeight™ 217.60‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Patterns of somatic mutation in human cancer genomes. Nature 2007 38.41
2 Signatures of mutational processes in human cancer. Nature 2013 21.63
3 Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature 2011 13.30
4 Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia. Nature 2011 13.18
5 The landscape of cancer genes and mutational processes in breast cancer. Nature 2012 11.24
6 Mutational processes molding the genomes of 21 breast cancers. Cell 2012 11.22
7 The life history of 21 breast cancers. Cell 2012 10.59
8 Lung cancer: intragenic ERBB2 kinase mutations in tumours. Nature 2004 8.35
9 Somatic mutations of the protein kinase gene family in human lung cancer. Cancer Res 2005 7.66
10 A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy. Cancer Res 2006 6.91
11 A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer. Nat Genet 2005 6.70
12 Clinical and biological implications of driver mutations in myelodysplastic syndromes. Blood 2013 6.50
13 Mutation analysis of 24 known cancer genes in the NCI-60 cell line set. Mol Cancer Ther 2006 4.09
14 DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis. Elife 2013 2.67
15 Sequence analysis of the protein kinase gene family in human testicular germ-cell tumors of adolescents and adults. Genes Chromosomes Cancer 2006 2.50
16 Genome sequencing and analysis of the Tasmanian devil and its transmissible cancer. Cell 2012 2.37
17 Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation. Nat Genet 2007 2.35
18 Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor. Am J Hum Genet 2007 2.07
19 Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation. Am J Hum Genet 2006 1.85
20 Single-cell paired-end genome sequencing reveals structural variation per cell cycle. Nucleic Acids Res 2013 1.77
21 Mutations in ZDHHC9, which encodes a palmitoyltransferase of NRAS and HRAS, cause X-linked mental retardation associated with a Marfanoid habitus. Am J Hum Genet 2007 1.73
22 Whole exome sequencing of adenoid cystic carcinoma. J Clin Invest 2013 1.58
23 The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models. Genome Biol 2013 1.54
24 Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma. Nat Genet 2013 1.45
25 Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes. J Pathol 2012 1.41
26 Mutations in the BRWD3 gene cause X-linked mental retardation associated with macrocephaly. Am J Hum Genet 2007 1.26
27 Aging as accelerated accumulation of somatic variants: whole-genome sequencing of centenarian and middle-aged monozygotic twin pairs. Twin Res Hum Genet 2013 0.89
28 Corrigendum: analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue. Nat Genet 2015 0.79
29 Polygenic in vivo validation of cancer mutations using transposons. Genome Biol 2014 0.75
30 Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers. Nat Genet 2017 0.75