Published in Curr Opin Cell Biol on August 03, 2007
ESCRT complexes and the biogenesis of multivesicular bodies. Curr Opin Cell Biol (2008) 3.90
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Large-scale identification of Legionella pneumophila Dot/Icm substrates that modulate host cell vesicle trafficking pathways. Cell Microbiol (2008) 1.47
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Differential effects of Usp14 and Uch-L1 on the ubiquitin proteasome system and synaptic activity. Mol Cell Neurosci (2008) 1.22
Opposing activities of the Snx3-retromer complex and ESCRT proteins mediate regulated cargo sorting at a common endosome. Mol Biol Cell (2008) 1.21
Ubiquitin regulates GGA3-mediated degradation of BACE1. J Biol Chem (2010) 1.16
Manganese-induced trafficking and turnover of the cis-Golgi glycoprotein GPP130. Mol Biol Cell (2010) 1.16
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Structure and function of the membrane deformation AAA ATPase Vps4. Biochim Biophys Acta (2011) 1.07
Coordination of substrate binding and ATP hydrolysis in Vps4-mediated ESCRT-III disassembly. Mol Biol Cell (2010) 1.06
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Endosomal trafficking of HIV-1 gag and genomic RNAs regulates viral egress. J Biol Chem (2009) 1.01
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Quality control for unfolded proteins at the plasma membrane. J Cell Biol (2010) 0.96
Dual roles of an Arabidopsis ESCRT component FREE1 in regulating vacuolar protein transport and autophagic degradation. Proc Natl Acad Sci U S A (2015) 0.95
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Posttranslational regulation of copper transporters. J Biol Inorg Chem (2009) 0.92
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Seven in absentia proteins affect plant growth and nodulation in Medicago truncatula. Plant Physiol (2008) 0.90
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The ocular albinism type 1 (OA1) GPCR is ubiquitinated and its traffic requires endosomal sorting complex responsible for transport (ESCRT) function. Proc Natl Acad Sci U S A (2011) 0.87
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Hrs controls sorting of the epithelial Na+ channel between endosomal degradation and recycling pathways. J Biol Chem (2010) 0.86
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The cytoplasmic tail of GM3 synthase defines its subcellular localization, stability, and in vivo activity. Mol Biol Cell (2009) 0.86
BACE1 protein endocytosis and trafficking are differentially regulated by ubiquitination at lysine 501 and the Di-leucine motif in the carboxyl terminus. J Biol Chem (2012) 0.84
A C-terminal sequence in the guanine nucleotide exchange factor Sec7 mediates Golgi association and interaction with the Rsp5 ubiquitin ligase. J Biol Chem (2008) 0.84
An iron-regulated and glycosylation-dependent proteasomal degradation pathway for the plasma membrane metal transporter ZIP14. Proc Natl Acad Sci U S A (2014) 0.84
USP32 is an active, membrane-bound ubiquitin protease overexpressed in breast cancers. Mamm Genome (2010) 0.81
Sonic Hedgehog modulates EGFR dependent proliferation of neural stem cells during late mouse embryogenesis through EGFR transactivation. Front Cell Neurosci (2013) 0.79
Novel ethyl methanesulfonate (EMS)-induced null alleles of the Drosophila homolog of LRRK2 reveal a crucial role in endolysosomal functions and autophagy in vivo. Dis Model Mech (2014) 0.78
Compartmentalizing intestinal epithelial cell toll-like receptors for immune surveillance. Cell Mol Life Sci (2015) 0.78
The complexity of vesicle transport factors in plants examined by orthology search. PLoS One (2014) 0.78
Posttranslational modifications of GLUT4 affect its subcellular localization and translocation. Int J Mol Sci (2013) 0.77
Endosomal sorting of GLUT4 and Gap1 is conserved between yeast and insulin-sensitive cells. J Cell Sci (2013) 0.77
Ubiquitin-dependent trafficking and turnover of ionotropic glutamate receptors. Front Mol Neurosci (2015) 0.77
The Plasma Membrane H+-ATPase AHA1 Plays a Major Role in Stomatal Opening in Response to Blue Light. Plant Physiol (2016) 0.76
The Endosome-associated Deubiquitinating Enzyme USP8 Regulates BACE1 Enzyme Ubiquitination and Degradation. J Biol Chem (2016) 0.76
Targeting CD83 for the treatment of graft-versus-host disease. Exp Ther Med (2013) 0.76
Structural and functional characterization of a ubiquitin variant engineered for tight and specific binding to an alpha-helical ubiquitin interacting motif. Protein Sci (2017) 0.75
Cell Adhesion Molecules and Ubiquitination-Functions and Significance. Biology (Basel) (2015) 0.75
Ubiquitination and dynactin regulate TMEPAI lysosomal trafficking. Sci Rep (2017) 0.75
Data integration in physiology using Bayes' rule and minimum Bayes' factors: deubiquitylating enzymes in the renal collecting duct. Physiol Genomics (2016) 0.75
Release of HIV-1 sequestered in the vesicles of oral and genital mucosal epithelial cells by epithelial-lymphocyte interaction. PLoS Pathog (2017) 0.75
Aneuploidy shortens replicative lifespan in Saccharomyces cerevisiae. Aging Cell (2016) 0.75
Receptor downregulation and multivesicular-body sorting. Nat Rev Mol Cell Biol (2002) 10.12
Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell (2001) 9.08
Rab conversion as a mechanism of progression from early to late endosomes. Cell (2005) 8.96
Proteasome-independent functions of ubiquitin in endocytosis and signaling. Science (2007) 6.65
Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis. Cell (1996) 6.51
The biogenesis of multivesicular endosomes. Nat Rev Mol Cell Biol (2004) 6.31
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes. Nat Cell Biol (2002) 5.83
Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation. Nat Cell Biol (2003) 5.43
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The ESCRT complexes: structure and mechanism of a membrane-trafficking network. Annu Rev Biophys Biomol Struct (2006) 5.21
Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain. Mol Cell (2006) 4.36
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling. Nat Cell Biol (2006) 4.05
The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors. Curr Biol (2001) 3.64
The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting. Nat Cell Biol (2002) 3.62
Bilayered clathrin coats on endosomal vacuoles are involved in protein sorting toward lysosomes. Mol Biol Cell (2002) 3.24
The ABC-transporter Ste6 accumulates in the plasma membrane in a ubiquitinated form in endocytosis mutants. EMBO J (1994) 3.10
Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting. EMBO J (2001) 3.05
STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes. J Biol Chem (2003) 3.00
Regulation of ubiquitin-binding proteins by monoubiquitination. Nat Cell Biol (2006) 2.99
Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes. EMBO J (2001) 2.97
Molecular mechanisms of coupled monoubiquitination. Nat Cell Biol (2006) 2.69
Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B. Cell (2005) 2.67
Components of a ubiquitin ligase complex specify polyubiquitination and intracellular trafficking of the general amino acid permease. J Cell Biol (2001) 2.65
Interactions of GGA3 with the ubiquitin sorting machinery. Nat Cell Biol (2004) 2.63
Endosomal and non-endosomal functions of ESCRT proteins. Trends Cell Biol (2006) 2.61
Monoubiquitin carries a novel internalization signal that is appended to activated receptors. EMBO J (2000) 2.54
Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signaling. Mol Cell (2005) 2.52
Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrin. J Cell Biol (2007) 2.52
Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules. EMBO J (2006) 2.39
Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward vesiculation. Mol Biol Cell (2006) 2.37
Dynein is required for receptor sorting and the morphogenesis of early endosomes. Nat Cell Biol (2006) 2.33
Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: role of Rab7 and RILP. Mol Cell Biol (2003) 2.33
Ubiquitin is required for sorting to the vacuole of the yeast general amino acid permease, Gap1. J Biol Chem (2001) 2.22
Epsin 1 is a polyubiquitin-selective clathrin-associated sorting protein. Traffic (2006) 2.20
Depletion of TSG101 forms a mammalian "Class E" compartment: a multicisternal early endosome with multiple sorting defects. J Cell Sci (2005) 2.19
bicoid RNA localization requires specific binding of an endosomal sorting complex. Nature (2007) 2.11
Endocytic delivery to lysosomes mediated by concurrent fusion and kissing events in living cells. Curr Biol (2005) 2.11
Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release. J Virol (2006) 2.06
Molecular basis of oligoubiquitin-dependent internalization of membrane proteins in Mammalian cells. Traffic (2006) 1.96
Late endosomes: sorting and partitioning in multivesicular bodies. Traffic (2001) 1.89
Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII. J Biol Chem (2005) 1.82
Direct sorting of the yeast uracil permease to the endosomal system is controlled by uracil binding and Rsp5p-dependent ubiquitylation. Mol Biol Cell (2003) 1.75
The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor. Mol Biol Cell (2006) 1.74
A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies. Nat Cell Biol (2002) 1.74
Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding. Genes Dev (2004) 1.73
Tollip and Tom1 form a complex and recruit ubiquitin-conjugated proteins onto early endosomes. J Biol Chem (2004) 1.50
Exploring the ESCRTing machinery in eukaryotes. Trends Plant Sci (2006) 1.47
The oxysterol-binding protein homologue ORP1L interacts with Rab7 and alters functional properties of late endocytic compartments. Mol Biol Cell (2005) 1.46
Decoding ubiquitin sorting signals for clathrin-dependent endocytosis by CLASPs. J Cell Sci (2007) 1.44
Rapid Ca2+-dependent decrease of protein ubiquitination at synapses. Proc Natl Acad Sci U S A (2003) 1.41
Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain. Nat Struct Mol Biol (2006) 1.41
Membrane dynamics and the biogenesis of lysosomes. Mol Membr Biol (2003) 1.40
Transport of LAPTM5 to lysosomes requires association with the ubiquitin ligase Nedd4, but not LAPTM5 ubiquitination. J Cell Biol (2006) 1.37
Tom1, a VHS domain-containing protein, interacts with tollip, ubiquitin, and clathrin. J Biol Chem (2003) 1.37
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GGA proteins: new players in the sorting game. J Cell Sci (2001) 1.22
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Intracellular trafficking of interleukin-1 receptor I requires Tollip. Curr Biol (2006) 1.18
The fission yeast homolog of the human transcription factor EAP30 blocks meiotic spindle pole body amplification. Dev Cell (2005) 1.14
The adaptor protein Tom1L1 is a negative regulator of Src mitogenic signaling induced by growth factors. Mol Cell Biol (2006) 1.07
Membrane traffic: GGAs sort ubiquitin. Curr Biol (2004) 1.05
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Monoubiquitylation of GGA3 by hVPS18 regulates its ubiquitin-binding ability. Biochem Biophys Res Commun (2006) 1.01
RILP interacts with VPS22 and VPS36 of ESCRT-II and regulates their membrane recruitment. Biochem Biophys Res Commun (2006) 0.99
RILP interacts with the VPS22 component of the ESCRT-II complex. Biochem Biophys Res Commun (2006) 0.99
Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis. J Cell Biol (2005) 3.07
Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules. EMBO J (2006) 2.39
Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton. Traffic (2002) 2.37
Protein-protein interactions of ESCRT complexes in the yeast Saccharomyces cerevisiae. Traffic (2004) 2.24
Spastin couples microtubule severing to membrane traffic in completion of cytokinesis and secretion. Traffic (2008) 2.16
Endocytic delivery to lysosomes mediated by concurrent fusion and kissing events in living cells. Curr Biol (2005) 2.11
Spastin and atlastin, two proteins mutated in autosomal-dominant hereditary spastic paraplegia, are binding partners. Hum Mol Genet (2005) 2.01
Mucolipin-1 is a lysosomal membrane protein required for intracellular lactosylceramide traffic. Traffic (2006) 1.92
Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII. J Biol Chem (2005) 1.82
Molecular basis for the sorting of the SNARE VAMP7 into endocytic clathrin-coated vesicles by the ArfGAP Hrb. Cell (2008) 1.75
Loss of myosin VI reduces secretion and the size of the Golgi in fibroblasts from Snell's waltzer mice. EMBO J (2003) 1.74
Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes. Mol Biol Cell (2002) 1.69
Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events. EMBO Rep (2004) 1.62
Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton. Mol Biol Cell (2003) 1.58
Controlled elimination of clathrin heavy-chain expression in DT40 lymphocytes. Science (2002) 1.45
Prevention and cure of systemic Escherichia coli K1 infection by modification of the bacterial phenotype. Antimicrob Agents Chemother (2004) 1.38
The role of mVps18p in clustering, fusion, and intracellular localization of late endocytic organelles. Mol Biol Cell (2003) 1.37
The hereditary spastic paraplegia proteins NIPA1, spastin and spartin are inhibitors of mammalian BMP signalling. Hum Mol Genet (2009) 1.35
Mistargeting of SH3TC2 away from the recycling endosome causes Charcot-Marie-Tooth disease type 4C. Hum Mol Genet (2009) 1.29
CUPpling calcium to lysosomal biogenesis. Trends Cell Biol (2004) 1.27
Differential use of two AP-3-mediated pathways by lysosomal membrane proteins. Traffic (2004) 1.21
Myosin VI, an actin motor for membrane traffic and cell migration. Traffic (2002) 1.20
Two motifs target Batten disease protein CLN3 to lysosomes in transfected nonneuronal and neuronal cells. Mol Biol Cell (2003) 1.16
Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5. Biochem J (2009) 1.15
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Delivery of endocytosed membrane proteins to the lysosome. Biochim Biophys Acta (2009) 1.03
Structural basis of Vps33A recruitment to the human HOPS complex by Vps16. Proc Natl Acad Sci U S A (2013) 1.03
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Structural basis of the intracellular sorting of the SNARE VAMP7 by the AP3 adaptor complex. Dev Cell (2012) 0.96
AP-1 and AP-3 facilitate lysosomal targeting of Batten disease protein CLN3 via its dileucine motif. J Biol Chem (2004) 0.95
The sodium/proton exchanger NHE8 regulates late endosomal morphology and function. Mol Biol Cell (2010) 0.94
The p55 tumour necrosis factor receptor TNFR1 contains a trans-Golgi network localization signal in the C-terminal region of its cytoplasmic tail. Biochem J (2002) 0.93
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