Synthesis and characterization of novel thiol-reactive poly(ethylene glycol) cross-linkers for extracellular-matrix-mimetic biomaterials.

PubWeight™: 1.22‹?› | Rank: Top 10%

🔗 View Article (PMID 17691843)

Published in Biomacromolecules on August 11, 2007

Authors

Janssen L Vanderhooft1, Brenda K Mann, Glenn D Prestwich

Author Affiliations

1: Department of Bioengineering, The University of Utah, 419 Wakara Way, Suite 205, Salt Lake City, Utah 84108-1257, USA.

Articles citing this

Hydrogels in regenerative medicine. Adv Mater (2009) 3.80

Hyaluronic acid hydrogels for biomedical applications. Adv Mater (2011) 2.51

Protein modification, bioconjugation, and disulfide bridging using bromomaleimides. J Am Chem Soc (2010) 1.89

Hydrolytically degradable poly(ethylene glycol) hydrogel scaffolds with tunable degradation and mechanical properties. Biomacromolecules (2010) 1.65

Hyaluronic acid-based clinical biomaterials derived for cell and molecule delivery in regenerative medicine. J Control Release (2011) 1.36

Thiol-selective fluorogenic probes for labeling and release. J Am Chem Soc (2009) 1.36

Modular extracellular matrices: solutions for the puzzle. Methods (2008) 1.16

Engineering a clinically-useful matrix for cell therapy. Organogenesis (2008) 1.06

Synthesis and characterization of tyramine-based hyaluronan hydrogels. J Mater Sci Mater Med (2008) 1.01

Engineered extracellular matrices with cleavable crosslinkers for cell expansion and easy cell recovery. Biomaterials (2008) 0.97

Sustained localized presentation of RNA interfering molecules from in situ forming hydrogels to guide stem cell osteogenic differentiation. Biomaterials (2014) 0.92

Synthesis, characterization and chondroprotective properties of a hyaluronan thioethyl ether derivative. Biomaterials (2007) 0.89

Silk fibroin and polyethylene glycol-based biocompatible tissue adhesives. J Biomed Mater Res A (2011) 0.87

Formulation Changes Affect Material Properties and Cell Behavior in HA-Based Hydrogels. Int J Cell Biol (2012) 0.79

Development of hydrogels and biomimetic regulators as tissue engineering scaffolds. Membranes (Basel) (2012) 0.79

Tissue engineering of heart valves: PEGylation of decellularized porcine aortic valve as a scaffold for in vitro recellularization. Biomed Eng Online (2013) 0.78

Encapsulated stem cells for cancer therapy. Biomatter (2013) 0.77

Effect of Carboxymethylation on the Rheological Properties of Hyaluronan. PLoS One (2016) 0.75

Self-healing polysaccharide-based hydrogels as injectable carriers for neural stem cells. Sci Rep (2016) 0.75

Articles by these authors

(truncated to the top 100)

Regulation of lung injury and repair by Toll-like receptors and hyaluronan. Nat Med (2005) 8.49

A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity. Nat Cell Biol (2002) 5.58

Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell (2004) 4.91

The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. Cell (2003) 3.36

Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist. Proc Natl Acad Sci U S A (2002) 3.01

Hyaluronic acid hydrogels for biomedical applications. Adv Mater (2011) 2.51

Hyaluronan-binding proteins: tying up the giant. J Biol Chem (2001) 2.20

In situ crosslinkable hyaluronan hydrogels for tissue engineering. Biomaterials (2003) 2.08

Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex. J Cell Biol (2002) 2.07

Disulfide cross-linked hyaluronan hydrogels. Biomacromolecules (2002) 2.06

Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event. Proc Natl Acad Sci U S A (2007) 2.03

Synthesis and evaluation of injectable, in situ crosslinkable synthetic extracellular matrices for tissue engineering. J Biomed Mater Res A (2006) 1.92

Lysophosphatidic acid induces neointima formation through PPARgamma activation. J Exp Med (2004) 1.86

Photoreceptor cGMP phosphodiesterase delta subunit (PDEdelta) functions as a prenyl-binding protein. J Biol Chem (2003) 1.80

Injectable glycosaminoglycan hydrogels for controlled release of human basic fibroblast growth factor. Biomaterials (2005) 1.79

Fluorogenic phospholipids as head group-selective reporters of phospholipase A activity. ACS Chem Biol (2006) 1.70

Disulfide-crosslinked hyaluronan-gelatin hydrogel films: a covalent mimic of the extracellular matrix for in vitro cell growth. Biomaterials (2003) 1.69

Vocal fold tissue repair in vivo using a synthetic extracellular matrix. Tissue Eng (2006) 1.66

Phosphatidylinositol (3,4,5)P3 is essential but not sufficient for protein kinase B (PKB) activation; phosphatidylinositol (3,4)P2 is required for PKB phosphorylation at Ser-473: studies using cells from SH2-containing inositol-5-phosphatase knockout mice. J Biol Chem (2002) 1.60

Heparin-regulated release of growth factors in vitro and angiogenic response in vivo to implanted hyaluronan hydrogels containing VEGF and bFGF. Biomaterials (2006) 1.58

Reduced postoperative intra-abdominal adhesions using Carbylan-SX, a semisynthetic glycosaminoglycan hydrogel. Fertil Steril (2006) 1.55

Dual activity lysophosphatidic acid receptor pan-antagonist/autotaxin inhibitor reduces breast cancer cell migration in vitro and causes tumor regression in vivo. Cancer Res (2009) 1.54

LPA-producing enzyme PA-PLA₁α regulates hair follicle development by modulating EGFR signalling. EMBO J (2011) 1.48

Adhesive and mechanical properties of hydrogels influence neurite extension. J Biomed Mater Res A (2005) 1.46

Lysophosphatidic acid is constitutively produced by human peritoneal mesothelial cells and enhances adhesion, migration, and invasion of ovarian cancer cells. Cancer Res (2006) 1.45

Phosphatidylinositol 4,5-bisphosphate regulates inspiratory burst activity in the neonatal mouse preBötzinger complex. J Physiol (2007) 1.44

Elephant albumin: a multipurpose pheromone shuttle. Chem Biol (2004) 1.41

Electrospun three-dimensional hyaluronic acid nanofibrous scaffolds. Biomaterials (2006) 1.40

Osteochondral defect repair with autologous bone marrow-derived mesenchymal stem cells in an injectable, in situ, cross-linked synthetic extracellular matrix. Tissue Eng (2006) 1.38

Glycosaminoglycan hydrogel films as bio-interactive dressings for wound healing. Biomaterials (2002) 1.38

Multivalent mechanism of membrane insertion by the FYVE domain. J Biol Chem (2003) 1.38

Inositol hexakisphosphate mobilizes an endomembrane store of calcium in guard cells. Proc Natl Acad Sci U S A (2003) 1.37

Attachment and spreading of fibroblasts on an RGD peptide-modified injectable hyaluronan hydrogel. J Biomed Mater Res A (2004) 1.37

Fluorogenic phospholipid substrate to detect lysophospholipase D/autotaxin activity. Org Lett (2006) 1.34

Myristoylated alanine-rich C kinase substrate (MARCKS) sequesters spin-labeled phosphatidylinositol 4,5-bisphosphate in lipid bilayers. J Biol Chem (2002) 1.34

Fibronectin functional domains coupled to hyaluronan stimulate adult human dermal fibroblast responses critical for wound healing. Tissue Eng (2006) 1.33

Alpha-substituted phosphonate analogues of lysophosphatidic acid (LPA) selectively inhibit production and action of LPA. ChemMedChem (2007) 1.32

A PHD finger motif in the C terminus of RAG2 modulates recombination activity. J Biol Chem (2005) 1.31

Rheological properties of cross-linked hyaluronan-gelatin hydrogels for tissue engineering. Macromol Biosci (2009) 1.30

Rheological characterization of in situ cross-linkable hyaluronan hydrogels. Biomacromolecules (2005) 1.30

Stereolithography of three-dimensional bioactive poly(ethylene glycol) constructs with encapsulated cells. Ann Biomed Eng (2006) 1.29

Combining electrospun scaffolds with electrosprayed hydrogels leads to three-dimensional cellularization of hybrid constructs. Biomacromolecules (2008) 1.28

In vivo engineering of the vocal fold extracellular matrix with injectable hyaluronic acid hydrogels: early effects on tissue repair and biomechanics in a rabbit model. Ann Otol Rhinol Laryngol (2005) 1.23

Low anticoagulant heparin targets multiple sites of inflammation, suppresses heparin-induced thrombocytopenia, and inhibits interaction of RAGE with its ligands. Am J Physiol Cell Physiol (2010) 1.21

Bioprinting vessel-like constructs using hyaluronan hydrogels crosslinked with tetrahedral polyethylene glycol tetracrylates. Biomaterials (2010) 1.19

Photoaffinity antigens for human gammadelta T cells. J Immunol (2008) 1.19

Enantioselective responses to a phosphorothioate analogue of lysophosphatidic acid with LPA3 receptor-selective agonist activity. J Med Chem (2003) 1.18

Lysophosphatidic acid production and action: validated targets in cancer? J Cell Biochem (2004) 1.17

Modular extracellular matrices: solutions for the puzzle. Methods (2008) 1.16

Synthesis of monofluorinated analogues of lysophosphatidic acid. J Org Chem (2003) 1.15

Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation. Am J Respir Crit Care Med (2013) 1.15

Biocompatibility and stability of disulfide-crosslinked hyaluronan films. Biomaterials (2005) 1.15

A monoclonal antibody to visualize PtdIns(3,4,5)P(3) in cells. J Histochem Cytochem (2002) 1.14

Tumor engineering: orthotopic cancer models in mice using cell-loaded, injectable, cross-linked hyaluronan-derived hydrogels. Tissue Eng (2007) 1.14

Functional performance of human cardiosphere-derived cells delivered in an in situ polymerizable hyaluronan-gelatin hydrogel. Biomaterials (2012) 1.14

Prevention of peritendinous adhesions using a hyaluronan-derived hydrogel film following partial-thickness flexor tendon injury. J Orthop Res (2008) 1.13

Inhibition of tumor growth and angiogenesis by a lysophosphatidic acid antagonist in an engineered three-dimensional lung cancer xenograft model. Cancer (2010) 1.13

Pulmonary autotaxin expression contributes to the pathogenesis of pulmonary fibrosis. Am J Respir Cell Mol Biol (2012) 1.13

Identification and biophysical characterization of a very-long-chain-fatty-acid-substituted phosphatidylinositol in yeast subcellular membranes. Biochem J (2004) 1.13

Crosslinked hyaluronan hydrogels containing mitomycin C reduce postoperative abdominal adhesions. Fertil Steril (2005) 1.12

Release of basic fibroblast growth factor from a crosslinked glycosaminoglycan hydrogel promotes wound healing. Wound Repair Regen (2007) 1.12

Nuclear magnetic resonance metabolomic footprinting of human hepatic stem cells and hepatoblasts cultured in hyaluronan-matrix hydrogels. Stem Cells (2008) 1.12

Layer by layer buildup of polysaccharide films: physical chemistry and cellular adhesion aspects. Langmuir (2004) 1.12

Regulation of lysophosphatidic acid receptor expression and function in human synoviocytes: implications for rheumatoid arthritis? Mol Pharmacol (2007) 1.10

Stimulation of in vivo angiogenesis using dual growth factor-loaded crosslinked glycosaminoglycan hydrogels. Biomaterials (2006) 1.08

Lipid phosphate phosphatases regulate lysophosphatidic acid production and signaling in platelets: studies using chemical inhibitors of lipid phosphate phosphatase activity. J Biol Chem (2003) 1.07

Intracellular delivery of phosphatidylinositol (3,4,5)-trisphosphate causes incorporation of glucose transporter 4 into the plasma membrane of muscle and fat cells without increasing glucose uptake. J Biol Chem (2004) 1.06

Dual growth factor-induced angiogenesis in vivo using hyaluronan hydrogel implants. Biomaterials (2005) 1.05

Chemical synthesis and molecular recognition of phosphatase-resistant analogues of phosphatidylinositol-3-phosphate. J Am Chem Soc (2006) 1.05

Augmentation of integrin-mediated mechanotransduction by hyaluronic acid. Biomaterials (2013) 1.05

Synthetic extracellular matrix enhances tumor growth and metastasis in an orthotopic mouse model of pancreatic adenocarcinoma. J Gastrointest Surg (2007) 1.05

Stabilized phosphatidylinositol-5-phosphate analogues as ligands for the nuclear protein ING2: chemistry, biology, and molecular modeling. J Am Chem Soc (2007) 1.05

The three-dimensional vascularization of growth factor-releasing hybrid scaffold of poly (epsilon-caprolactone)/collagen fibers and hyaluronic acid hydrogel. Biomaterials (2011) 1.05

Hyaluronic acid-based hydrogels functionalized with heparin that support controlled release of bioactive BMP-2. Biomaterials (2012) 1.03

Concise synthesis of acyl migration-blocked 1,1-difluorinated analogues of lysophosphatidic acid. J Org Chem (2002) 1.03

Inositol polyphosphates, diphosphoinositol polyphosphates and phosphatidylinositol polyphosphate lipids: structure, synthesis, and development of probes for studying biological activity. Nat Prod Rep (2010) 1.03

Adipose tissue engineering with naturally derived scaffolds and adipose-derived stem cells. Biomaterials (2007) 1.02

Targeted delivery of doxorubicin by HPMA copolymer-hyaluronan bioconjugates. Pharm Res (2002) 1.01

Regulation of hepatic stem/progenitor phenotype by microenvironment stiffness in hydrogel models of the human liver stem cell niche. Biomaterials (2011) 1.01

Reprogramming cardiomyocyte mechanosensing by crosstalk between integrins and hyaluronic acid receptors. J Biomech (2011) 1.00

A cross-linked hyaluronan gel accelerates healing of corneal epithelial abrasion and alkali burn injuries in rabbits. Vet Ophthalmol (2010) 1.00

Synthesis of migration-resistant hydroxyethoxy analogues of lysophosphatidic acid. Org Lett (2003) 0.99

Recruitment of endogenous stem cells for tissue repair. Macromol Biosci (2008) 0.99

Intracellular uptake and trafficking of Pluronic micelles in drug-sensitive and MDR cells: effect on the intracellular drug localization. J Pharm Sci (2002) 0.99

Photocrosslinkable hyaluronan-gelatin hydrogels for two-step bioprinting. Tissue Eng Part A (2010) 0.99

Use of hyaluronan-derived hydrogels for three-dimensional cell culture and tumor xenografts. Curr Protoc Cell Biol (2008) 0.98

Negative feedback regulation of Rac in leukocytes from mice expressing a constitutively active phosphatidylinositol 3-kinase gamma. Proc Natl Acad Sci U S A (2007) 0.98

Competitive fluorescence polarization assays for the detection of phosphoinositide kinase and phosphatase activity. Comb Chem High Throughput Screen (2003) 0.98

Characterization of sphingosine-1-phosphate lyase activity by electrospray ionization-liquid chromatography/tandem mass spectrometry quantitation of (2E)-hexadecenal. Anal Biochem (2010) 0.97

Engineered extracellular matrices with cleavable crosslinkers for cell expansion and easy cell recovery. Biomaterials (2008) 0.97

Synthesis of alpha-fluorinated phosphonates from alpha-fluorovinylphosphonates: a new route to analogues of lysophosphatidic acid. Org Lett (2003) 0.97

Effects of extracellular matrix analogues on primary human fibroblast behavior. Acta Biomater (2007) 0.96

A real-time fluorogenic phospholipase A(2) assay for biochemical and cellular activity measurements. Chem Biol (2002) 0.96

Microvascular maturity elicited in tissue treated with cytokine-loaded hyaluronan-based hydrogels. Biomaterials (2008) 0.96

Evaluating dual activity LPA receptor pan-antagonist/autotaxin inhibitors as anti-cancer agents in vivo using engineered human tumors. Prostaglandins Other Lipid Mediat (2009) 0.96

Structure-activity relationships of fluorinated lysophosphatidic acid analogues. J Med Chem (2005) 0.96

Accelerated repair of cortical bone defects using a synthetic extracellular matrix to deliver human demineralized bone matrix. J Orthop Res (2006) 0.96

Effect of gelatin on heparin regulation of cytokine release from hyaluronan-based hydrogels. Drug Deliv (2008) 0.96

The generation of 3-D tissue models based on hyaluronan hydrogel-coated microcarriers within a rotating wall vessel bioreactor. Biomaterials (2010) 0.95

Dynamically crosslinked gold nanoparticle - hyaluronan hydrogels. Adv Mater (2010) 0.94