Published in J Biol Chem on February 01, 2002
Electrostatic sequestration of PIP2 on phospholipid membranes by basic/aromatic regions of proteins. Biophys J (2004) 2.66
Ras nanoclusters: molecular structure and assembly. Semin Cell Dev Biol (2007) 1.56
Fluorescence correlation spectroscopy studies of Peptide and protein binding to phospholipid vesicles. Biophys J (2004) 1.47
A computational model for the electrostatic sequestration of PI(4,5)P2 by membrane-adsorbed basic peptides. Biophys J (2004) 1.32
Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4,5-biphosphate manipulators. Pflugers Arch (2008) 1.31
Computational methods for biomolecular electrostatics. Methods Cell Biol (2008) 1.27
Basic residues in the Mason-Pfizer monkey virus gag matrix domain regulate intracellular trafficking and capsid-membrane interactions. J Virol (2007) 1.24
Use of EPR power saturation to analyze the membrane-docking geometries of peripheral proteins: applications to C2 domains. Annu Rev Biophys Biomol Struct (2005) 1.23
Increased concentration of polyvalent phospholipids in the adsorption domain of a charged protein. Biophys J (2004) 1.14
Domain formation induced by the adsorption of charged proteins on mixed lipid membranes. Biophys J (2004) 1.12
Location of the myristoylated alanine-rich C-kinase substrate (MARCKS) effector domain in negatively charged phospholipid bicelles. Biophys J (2003) 1.08
Phosphatidylinositol-4,5-bisphosphate regulates epidermal growth factor receptor activation. Pflugers Arch (2010) 1.04
A possible effector role for the pleckstrin homology (PH) domain of dynamin. Proc Natl Acad Sci U S A (2009) 1.04
Combined electrostatics and hydrogen bonding determine intermolecular interactions between polyphosphoinositides. J Am Chem Soc (2008) 1.00
Lateral diffusion of peripheral membrane proteins on supported lipid bilayers is controlled by the additive frictional drags of (1) bound lipids and (2) protein domains penetrating into the bilayer hydrocarbon core. Chem Phys Lipids (2013) 0.93
Reconstitution of KCNE1 into lipid bilayers: comparing the structural, dynamic, and activity differences in micelle and vesicle environments. Biochemistry (2011) 0.92
An early stage of Mason-Pfizer monkey virus budding is regulated by the hydrophobicity of the Gag matrix domain core. J Virol (2004) 0.92
Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway. Biophys J (2016) 0.90
Single-molecule studies reveal a hidden key step in the activation mechanism of membrane-bound protein kinase C-α. Biochemistry (2014) 0.88
CHARMM-GUI HMMM Builder for Membrane Simulations with the Highly Mobile Membrane-Mimetic Model. Biophys J (2015) 0.87
The "electrostatic-switch" mechanism: Monte Carlo study of MARCKS-membrane interaction. Biophys J (2008) 0.84
Membrane position of a basic aromatic peptide that sequesters phosphatidylinositol 4,5 bisphosphate determined by site-directed spin labeling and high-resolution NMR. Biophys J (2004) 0.83
Phospho-regulated Drosophila adducin is a determinant of synaptic plasticity in a complex with Dlg and PIP2 at the larval neuromuscular junction. Biol Open (2014) 0.79
Drugging Membrane Protein Interactions. Annu Rev Biomed Eng (2016) 0.78
Probing Structural Dynamics and Topology of the KCNE1 Membrane Protein in Lipid Bilayers via Site-Directed Spin Labeling and Electron Paramagnetic Resonance Spectroscopy. Biochemistry (2015) 0.77
Lipid-Targeting Peptide Probes for Extracellular Vesicles. J Cell Physiol (2016) 0.75
Effects of Spin-Labels on Membrane Burial Depth of MARCKS-ED Residues. Biophys J (2016) 0.75
Watching Signaling in Action: Single Molecule Studies of a Reaction Circuit Involved in Chemotaxis. Biophys J (2016) 0.75
Generation and intracellular trafficking of a polysialic acid-carrying fragment of the neural cell adhesion molecule NCAM to the cell nucleus. Sci Rep (2017) 0.75
Regulation of lung injury and repair by Toll-like receptors and hyaluronan. Nat Med (2005) 8.49
A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity. Nat Cell Biol (2002) 5.58
Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell (2004) 4.91
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. Cell (2003) 3.36
Recent advances and applications of site-directed spin labeling. Curr Opin Struct Biol (2006) 3.12
Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist. Proc Natl Acad Sci U S A (2002) 3.01
Electrostatic sequestration of PIP2 on phospholipid membranes by basic/aromatic regions of proteins. Biophys J (2004) 2.66
Hyaluronic acid hydrogels for biomedical applications. Adv Mater (2011) 2.51
Hyaluronan-binding proteins: tying up the giant. J Biol Chem (2001) 2.20
In situ crosslinkable hyaluronan hydrogels for tissue engineering. Biomaterials (2003) 2.08
Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex. J Cell Biol (2002) 2.07
Disulfide cross-linked hyaluronan hydrogels. Biomacromolecules (2002) 2.06
Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event. Proc Natl Acad Sci U S A (2007) 2.03
NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation. Mol Cell (2008) 1.92
Synthesis and evaluation of injectable, in situ crosslinkable synthetic extracellular matrices for tissue engineering. J Biomed Mater Res A (2006) 1.92
Lysophosphatidic acid induces neointima formation through PPARgamma activation. J Exp Med (2004) 1.86
Photoreceptor cGMP phosphodiesterase delta subunit (PDEdelta) functions as a prenyl-binding protein. J Biol Chem (2003) 1.80
Injectable glycosaminoglycan hydrogels for controlled release of human basic fibroblast growth factor. Biomaterials (2005) 1.79
Fluorogenic phospholipids as head group-selective reporters of phospholipase A activity. ACS Chem Biol (2006) 1.70
Disulfide-crosslinked hyaluronan-gelatin hydrogel films: a covalent mimic of the extracellular matrix for in vitro cell growth. Biomaterials (2003) 1.69
Vocal fold tissue repair in vivo using a synthetic extracellular matrix. Tissue Eng (2006) 1.66
Heparin-regulated release of growth factors in vitro and angiogenic response in vivo to implanted hyaluronan hydrogels containing VEGF and bFGF. Biomaterials (2006) 1.58
Dynamic structure of lipid-bound synaptobrevin suggests a nucleation-propagation mechanism for trans-SNARE complex formation. Proc Natl Acad Sci U S A (2009) 1.57
Membrane orientation and position of the C2 domain from cPLA2 by site-directed spin labeling. Biochemistry (2002) 1.57
Reduced postoperative intra-abdominal adhesions using Carbylan-SX, a semisynthetic glycosaminoglycan hydrogel. Fertil Steril (2006) 1.55
Position of synaptotagmin I at the membrane interface: cooperative interactions of tandem C2 domains. Biochemistry (2006) 1.54
Dual activity lysophosphatidic acid receptor pan-antagonist/autotaxin inhibitor reduces breast cancer cell migration in vitro and causes tumor regression in vivo. Cancer Res (2009) 1.54
LPA-producing enzyme PA-PLA₁α regulates hair follicle development by modulating EGFR signalling. EMBO J (2011) 1.48
Membrane-bound orientation and position of the synaptotagmin I C2A domain by site-directed spin labeling. Biochemistry (2003) 1.47
Lysophosphatidic acid is constitutively produced by human peritoneal mesothelial cells and enhances adhesion, migration, and invasion of ovarian cancer cells. Cancer Res (2006) 1.45
Phosphatidylinositol 4,5-bisphosphate regulates inspiratory burst activity in the neonatal mouse preBötzinger complex. J Physiol (2007) 1.44
Elephant albumin: a multipurpose pheromone shuttle. Chem Biol (2004) 1.41
Electrospun three-dimensional hyaluronic acid nanofibrous scaffolds. Biomaterials (2006) 1.40
Osteochondral defect repair with autologous bone marrow-derived mesenchymal stem cells in an injectable, in situ, cross-linked synthetic extracellular matrix. Tissue Eng (2006) 1.38
Glycosaminoglycan hydrogel films as bio-interactive dressings for wound healing. Biomaterials (2002) 1.38
Multivalent mechanism of membrane insertion by the FYVE domain. J Biol Chem (2003) 1.38
Inositol hexakisphosphate mobilizes an endomembrane store of calcium in guard cells. Proc Natl Acad Sci U S A (2003) 1.37
Attachment and spreading of fibroblasts on an RGD peptide-modified injectable hyaluronan hydrogel. J Biomed Mater Res A (2004) 1.37
The structure of the coiled-coil domain of Ndel1 and the basis of its interaction with Lis1, the causal protein of Miller-Dieker lissencephaly. Structure (2007) 1.36
Fluorogenic phospholipid substrate to detect lysophospholipase D/autotaxin activity. Org Lett (2006) 1.34
Fibronectin functional domains coupled to hyaluronan stimulate adult human dermal fibroblast responses critical for wound healing. Tissue Eng (2006) 1.33
Alpha-substituted phosphonate analogues of lysophosphatidic acid (LPA) selectively inhibit production and action of LPA. ChemMedChem (2007) 1.32
Substrate-induced conformational changes of the periplasmic N-terminus of an outer-membrane transporter by site-directed spin labeling. Biochemistry (2003) 1.31
A PHD finger motif in the C terminus of RAG2 modulates recombination activity. J Biol Chem (2005) 1.31
Rheological properties of cross-linked hyaluronan-gelatin hydrogels for tissue engineering. Macromol Biosci (2009) 1.30
Spectroscopic evidence that osmolytes used in crystallization buffers inhibit a conformation change in a membrane protein. Biochemistry (2003) 1.30
Rheological characterization of in situ cross-linkable hyaluronan hydrogels. Biomacromolecules (2005) 1.30
Combining electrospun scaffolds with electrosprayed hydrogels leads to three-dimensional cellularization of hybrid constructs. Biomacromolecules (2008) 1.28
Membrane-bound orientation and position of the synaptotagmin C2B domain determined by site-directed spin labeling. Biochemistry (2005) 1.27
In vivo engineering of the vocal fold extracellular matrix with injectable hyaluronic acid hydrogels: early effects on tissue repair and biomechanics in a rabbit model. Ann Otol Rhinol Laryngol (2005) 1.23
Solution structure of the ESCRT-I complex by small-angle X-ray scattering, EPR, and FRET spectroscopy. Proc Natl Acad Sci U S A (2011) 1.22
Synthesis and characterization of novel thiol-reactive poly(ethylene glycol) cross-linkers for extracellular-matrix-mimetic biomaterials. Biomacromolecules (2007) 1.22
Low anticoagulant heparin targets multiple sites of inflammation, suppresses heparin-induced thrombocytopenia, and inhibits interaction of RAGE with its ligands. Am J Physiol Cell Physiol (2010) 1.21
Substrate-dependent unfolding of the energy coupling motif of a membrane transport protein determined by double electron-electron resonance. Biochemistry (2006) 1.20
Solutes modify a conformational transition in a membrane transport protein. Biophys J (2006) 1.20
Bioprinting vessel-like constructs using hyaluronan hydrogels crosslinked with tetrahedral polyethylene glycol tetracrylates. Biomaterials (2010) 1.19
Photoaffinity antigens for human gammadelta T cells. J Immunol (2008) 1.19
Enantioselective responses to a phosphorothioate analogue of lysophosphatidic acid with LPA3 receptor-selective agonist activity. J Med Chem (2003) 1.18
Structure and dynamics of the beta-barrel of the membrane transporter BtuB by site-directed spin labeling. Biochemistry (2002) 1.18
Solution and membrane-bound conformations of the tandem C2A and C2B domains of synaptotagmin 1: Evidence for bilayer bridging. J Mol Biol (2009) 1.17
Lysophosphatidic acid production and action: validated targets in cancer? J Cell Biochem (2004) 1.17
Conformational exchange in a membrane transport protein is altered in protein crystals. Biophys J (2010) 1.17
Modular extracellular matrices: solutions for the puzzle. Methods (2008) 1.16
Synthesis of monofluorinated analogues of lysophosphatidic acid. J Org Chem (2003) 1.15
Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation. Am J Respir Crit Care Med (2013) 1.15
Biocompatibility and stability of disulfide-crosslinked hyaluronan films. Biomaterials (2005) 1.15
A monoclonal antibody to visualize PtdIns(3,4,5)P(3) in cells. J Histochem Cytochem (2002) 1.14
Tumor engineering: orthotopic cancer models in mice using cell-loaded, injectable, cross-linked hyaluronan-derived hydrogels. Tissue Eng (2007) 1.14
Functional performance of human cardiosphere-derived cells delivered in an in situ polymerizable hyaluronan-gelatin hydrogel. Biomaterials (2012) 1.14
Prevention of peritendinous adhesions using a hyaluronan-derived hydrogel film following partial-thickness flexor tendon injury. J Orthop Res (2008) 1.13
Pulmonary autotaxin expression contributes to the pathogenesis of pulmonary fibrosis. Am J Respir Cell Mol Biol (2012) 1.13
Inhibition of tumor growth and angiogenesis by a lysophosphatidic acid antagonist in an engineered three-dimensional lung cancer xenograft model. Cancer (2010) 1.13
Identification and biophysical characterization of a very-long-chain-fatty-acid-substituted phosphatidylinositol in yeast subcellular membranes. Biochem J (2004) 1.13
Crosslinked hyaluronan hydrogels containing mitomycin C reduce postoperative abdominal adhesions. Fertil Steril (2005) 1.12
Solutes alter the conformation of the ligand binding loops in outer membrane transporters. Biochemistry (2007) 1.12
Nuclear magnetic resonance metabolomic footprinting of human hepatic stem cells and hepatoblasts cultured in hyaluronan-matrix hydrogels. Stem Cells (2008) 1.12
Release of basic fibroblast growth factor from a crosslinked glycosaminoglycan hydrogel promotes wound healing. Wound Repair Regen (2007) 1.12
Layer by layer buildup of polysaccharide films: physical chemistry and cellular adhesion aspects. Langmuir (2004) 1.12
Regulation of lysophosphatidic acid receptor expression and function in human synoviocytes: implications for rheumatoid arthritis? Mol Pharmacol (2007) 1.10
Location of the myristoylated alanine-rich C-kinase substrate (MARCKS) effector domain in negatively charged phospholipid bicelles. Biophys J (2003) 1.08
Differential substrate-induced signaling through the TonB-dependent transporter BtuB. Proc Natl Acad Sci U S A (2003) 1.08
Stimulation of in vivo angiogenesis using dual growth factor-loaded crosslinked glycosaminoglycan hydrogels. Biomaterials (2006) 1.08
Lipid phosphate phosphatases regulate lysophosphatidic acid production and signaling in platelets: studies using chemical inhibitors of lipid phosphate phosphatase activity. J Biol Chem (2003) 1.07
Intracellular delivery of phosphatidylinositol (3,4,5)-trisphosphate causes incorporation of glucose transporter 4 into the plasma membrane of muscle and fat cells without increasing glucose uptake. J Biol Chem (2004) 1.06
Phosphatidylinositol 4,5-bisphosphate alters synaptotagmin 1 membrane docking and drives opposing bilayers closer together. Biochemistry (2011) 1.06
Solution structure of the ESCRT-I and -II supercomplex: implications for membrane budding and scission. Structure (2012) 1.06
Dual growth factor-induced angiogenesis in vivo using hyaluronan hydrogel implants. Biomaterials (2005) 1.05
Chemical synthesis and molecular recognition of phosphatase-resistant analogues of phosphatidylinositol-3-phosphate. J Am Chem Soc (2006) 1.05
Augmentation of integrin-mediated mechanotransduction by hyaluronic acid. Biomaterials (2013) 1.05
Synthetic extracellular matrix enhances tumor growth and metastasis in an orthotopic mouse model of pancreatic adenocarcinoma. J Gastrointest Surg (2007) 1.05
Stabilized phosphatidylinositol-5-phosphate analogues as ligands for the nuclear protein ING2: chemistry, biology, and molecular modeling. J Am Chem Soc (2007) 1.05
The calcium-dependent and calcium-independent membrane binding of synaptotagmin 1: two modes of C2B binding. J Mol Biol (2009) 1.05
The three-dimensional vascularization of growth factor-releasing hybrid scaffold of poly (epsilon-caprolactone)/collagen fibers and hyaluronic acid hydrogel. Biomaterials (2011) 1.05
Hyaluronic acid-based hydrogels functionalized with heparin that support controlled release of bioactive BMP-2. Biomaterials (2012) 1.03