Published in Ann Neurol on September 01, 2007
Advances in autism genetics: on the threshold of a new neurobiology. Nat Rev Genet (2008) 12.18
A genome-wide linkage and association scan reveals novel loci for autism. Nature (2009) 4.76
Immune transcriptome alterations in the temporal cortex of subjects with autism. Neurobiol Dis (2008) 2.88
The conundrums of understanding genetic risks for autism spectrum disorders. Nat Neurosci (2011) 2.61
Genomic and epigenetic evidence for oxytocin receptor deficiency in autism. BMC Med (2009) 2.60
Consensus paper: pathological role of the cerebellum in autism. Cerebellum (2012) 2.32
Traffic-related air pollution, particulate matter, and autism. JAMA Psychiatry (2013) 2.24
Autism and brain development. Cell (2008) 2.01
Differential monocyte responses to TLR ligands in children with autism spectrum disorders. Brain Behav Immun (2009) 1.86
Altered expression of genes involved in inflammation and apoptosis in frontal cortex in major depression. Mol Psychiatry (2010) 1.66
The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders. J Clin Invest (2009) 1.66
Genetic evidence implicating multiple genes in the MET receptor tyrosine kinase pathway in autism spectrum disorder. Autism Res (2008) 1.61
Association of genetic variation in the MET proto-oncogene with schizophrenia and general cognitive ability. Am J Psychiatry (2010) 1.58
Altered T cell responses in children with autism. Brain Behav Immun (2010) 1.53
Gene expression profiling of lymphoblasts from autistic and nonaffected sib pairs: altered pathways in neuronal development and steroid biosynthesis. PLoS One (2009) 1.39
Reduced levels of immunoglobulin in children with autism correlates with behavioral symptoms. Autism Res (2008) 1.37
Autism-associated promoter variant in MET impacts functional and structural brain networks. Neuron (2012) 1.29
Current developments in the genetics of autism: from phenome to genome. J Neuropathol Exp Neurol (2008) 1.26
MET and autism susceptibility: family and case-control studies. Eur J Hum Genet (2008) 1.24
Circuit-specific intracortical hyperconnectivity in mice with deletion of the autism-associated Met receptor tyrosine kinase. J Neurosci (2011) 1.22
Genetics of autistic disorders: review and clinical implications. Eur Child Adolesc Psychiatry (2009) 1.19
The oxytocin receptor gene (OXTR) is associated with autism spectrum disorder: a meta-analysis. Mol Psychiatry (2014) 1.18
Convulsing toward the pathophysiology of autism. Brain Dev (2008) 1.15
Immune mediators in the brain and peripheral tissues in autism spectrum disorder. Nat Rev Neurosci (2015) 1.13
Dynamic gene and protein expression patterns of the autism-associated met receptor tyrosine kinase in the developing mouse forebrain. J Comp Neurol (2009) 1.13
Synaptic microcircuit dysfunction in genetic models of neurodevelopmental disorders: focus on Mecp2 and Met. Curr Opin Neurobiol (2011) 1.12
Evidence of cell-nonautonomous changes in dendrite and dendritic spine morphology in the met-signaling-deficient mouse forebrain. J Comp Neurol (2010) 1.09
Regulation of MET by FOXP2, genes implicated in higher cognitive dysfunction and autism risk. J Neurosci (2011) 1.07
The autism risk genes MET and PLAUR differentially impact cortical development. Autism Res (2010) 1.04
Autism spectrum disorder causes, mechanisms, and treatments: focus on neuronal synapses. Front Mol Neurosci (2013) 1.04
The autism susceptibility gene met regulates zebrafish cerebellar development and facial motor neuron migration. Dev Biol (2009) 1.03
Association of a MET genetic variant with autism-associated maternal autoantibodies to fetal brain proteins and cytokine expression. Transl Psychiatry (2011) 1.02
Autism spectrum disorder: interaction of air pollution with the MET receptor tyrosine kinase gene. Epidemiology (2014) 1.02
Hepatocyte growth factor (HGF) modulates GABAergic inhibition and seizure susceptibility. Exp Neurol (2009) 1.01
Prenatal polycyclic aromatic hydrocarbon exposure leads to behavioral deficits and downregulation of receptor tyrosine kinase, MET. Toxicol Sci (2010) 1.00
A review of the evidence for the canonical Wnt pathway in autism spectrum disorders. Mol Autism (2012) 0.97
Evidence for dysregulation of axonal growth and guidance in the etiology of ASD. Front Hum Neurosci (2013) 0.95
Conserved subcortical and divergent cortical expression of proteins encoded by orthologs of the autism risk gene MET. Cereb Cortex (2010) 0.95
The Role of Epigenetic Change in Autism Spectrum Disorders. Front Neurol (2015) 0.95
Genome-wide linkage in Utah autism pedigrees. Mol Psychiatry (2009) 0.93
Wired for behaviors: from development to function of innate limbic system circuitry. Front Mol Neurosci (2012) 0.92
Autism risk gene MET variation and cortical thickness in typically developing children and adolescents. Autism Res (2012) 0.90
Memory acquisition and retrieval impact different epigenetic processes that regulate gene expression. BMC Genomics (2015) 0.89
MET receptor tyrosine kinase controls dendritic complexity, spine morphogenesis, and glutamatergic synapse maturation in the hippocampus. J Neurosci (2014) 0.88
Prenatal expression of MET receptor tyrosine kinase in the fetal mouse dorsal raphe nuclei and the visceral motor/sensory brainstem. Dev Neurosci (2013) 0.87
Replication of the association of a MET variant with autism in a Chinese Han population. PLoS One (2011) 0.86
The Impact of Neuroimmune Alterations in Autism Spectrum Disorder. Front Psychiatry (2015) 0.86
Transcriptional regulation of the MET receptor tyrosine kinase gene by MeCP2 and sex-specific expression in autism and Rett syndrome. Transl Psychiatry (2013) 0.85
AKAPs integrate genetic findings for autism spectrum disorders. Transl Psychiatry (2013) 0.85
MET receptor tyrosine kinase as an autism genetic risk factor. Int Rev Neurobiol (2013) 0.84
Decreased levels of EGF in plasma of children with autism spectrum disorder. Autism Res Treat (2012) 0.83
Constipation in children with autism and autistic spectrum disorder. Pediatr Surg Int (2010) 0.81
Examining the genetic and neural components of cognitive flexibility using mice. Physiol Behav (2012) 0.80
MET and AKT genetic influence on facial emotion perception. PLoS One (2012) 0.79
The autism-associated MET receptor tyrosine kinase engages early neuronal growth mechanism and controls glutamatergic circuits development in the forebrain. Mol Psychiatry (2016) 0.79
Modeling autism: a systems biology approach. J Clin Bioinforma (2012) 0.79
Describing the hexapeptide identity platform between the influenza A H5N1 and Homo sapiens proteomes. Biologics (2010) 0.79
The Pleiotropic MET Receptor Network: Circuit Development and the Neural-Medical Interface of Autism. Biol Psychiatry (2016) 0.78
Complete or partial reduction of the Met receptor tyrosine kinase in distinct circuits differentially impacts mouse behavior. J Neurodev Disord (2015) 0.78
Recent Advances in the Genetics of Vocal Learning. Comp Cogn Behav Rev (2015) 0.78
Differential methylation at the RELN gene promoter in temporal cortex from autistic and typically developing post-puberal subjects. J Neurodev Disord (2016) 0.77
Autism Linked to Increased Oncogene Mutations but Decreased Cancer Rate. PLoS One (2016) 0.77
When linkage signal for autism MET candidate gene. Eur J Hum Genet (2008) 0.77
Receptor Tyrosine Kinase MET Interactome and Neurodevelopmental Disorder Partners at the Developing Synapse. Biol Psychiatry (2016) 0.77
Morphological Alterations in the Thalamus, Striatum, and Pallidum in Autism Spectrum Disorder. Neuropsychopharmacology (2016) 0.76
Dynamic Akt/mTOR Signaling in Children with Autism Spectrum Disorder. Front Pediatr (2017) 0.75
Hepatocyte Growth Factor Modulates MET Receptor Tyrosine Kinase and β-Catenin Functional Interactions to Enhance Synapse Formation. eNeuro (2016) 0.75
Predicting Autism Spectrum Disorder Using Blood-based Gene Expression Signatures and Machine Learning. Clin Psychopharmacol Neurosci (2017) 0.75
Mechanisms regulating dendritic arbor patterning. Cell Mol Life Sci (2017) 0.75
Autism spectrum disorders: developmental disconnection syndromes. Curr Opin Neurobiol (2007) 6.96
Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia. J Neurosci (2003) 4.86
Schizophrenia as a disorder of neurodevelopment. Annu Rev Neurosci (2002) 4.36
Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice. Cell (2005) 4.25
Maternal immune activation alters fetal brain development through interleukin-6. J Neurosci (2007) 4.06
A genetic variant that disrupts MET transcription is associated with autism. Proc Natl Acad Sci U S A (2006) 3.55
Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia. Am J Psychiatry (2008) 3.16
Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients. Ann Neurol (2006) 2.93
Immune transcriptome alterations in the temporal cortex of subjects with autism. Neurobiol Dis (2008) 2.88
A transient placental source of serotonin for the fetal forebrain. Nature (2011) 2.71
Serotonin modulates the response of embryonic thalamocortical axons to netrin-1. Nat Neurosci (2007) 2.70
The conundrums of understanding genetic risks for autism spectrum disorders. Nat Neurosci (2011) 2.61
Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: a consensus report. Pediatrics (2010) 2.45
Prenatal exposure to drugs: effects on brain development and implications for policy and education. Nat Rev Neurosci (2009) 2.33
Consensus paper: pathological role of the cerebellum in autism. Cerebellum (2012) 2.32
Genetic disruption of cortical interneuron development causes region- and GABA cell type-specific deficits, epilepsy, and behavioral dysfunction. J Neurosci (2003) 2.18
Molecular evidence for increased expression of genes related to immune and chaperone function in the prefrontal cortex in schizophrenia. Biol Psychiatry (2007) 2.12
Association of a functional deficit of the BKCa channel, a synaptic regulator of neuronal excitability, with autism and mental retardation. Am J Psychiatry (2006) 2.05
How the timing and quality of early experiences influence the development of brain architecture. Child Dev (2010) 1.87
Gene expression profiling reveals alterations of specific metabolic pathways in schizophrenia. J Neurosci (2002) 1.79
Early experience modifies the postnatal assembly of autonomic emotional motor circuits in rats. J Neurosci (2005) 1.76
The organization of the transcriptional network in specific neuronal classes. Mol Syst Biol (2009) 1.74
Association and linkage analyses of RGS4 polymorphisms in schizophrenia. Hum Mol Genet (2002) 1.68
Critical appraisal of DNA microarrays in psychiatric genomics. Biol Psychiatry (2006) 1.66
Genetic evidence implicating multiple genes in the MET receptor tyrosine kinase pathway in autism spectrum disorder. Autism Res (2008) 1.61
Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling. Nature (2009) 1.59
RGS4-dependent attenuation of M4 autoreceptor function in striatal cholinergic interneurons following dopamine depletion. Nat Neurosci (2006) 1.58
Gastrointestinal dysfunction in autism: parental report, clinical evaluation, and associated factors. Autism Res (2012) 1.55
Association of autism with polyomavirus infection in postmortem brains. J Neurovirol (2010) 1.52
Dissociation of corticothalamic and thalamocortical axon targeting by an EphA7-mediated mechanism. Neuron (2005) 1.44
Distinct genetic risk based on association of MET in families with co-occurring autism and gastrointestinal conditions. Pediatrics (2009) 1.37
Amygdala gene expression correlates of social behavior in monkeys experiencing maternal separation. J Neurosci (2007) 1.35
Making the case for a candidate vulnerability gene in schizophrenia: Convergent evidence for regulator of G-protein signaling 4 (RGS4). Biol Psychiatry (2006) 1.34
Single-neuron RNA-Seq: technical feasibility and reproducibility. Front Genet (2012) 1.32
Autism-associated promoter variant in MET impacts functional and structural brain networks. Neuron (2012) 1.29
RGS4 is a negative regulator of insulin release from pancreatic beta-cells in vitro and in vivo. Proc Natl Acad Sci U S A (2010) 1.25
Circuit-specific intracortical hyperconnectivity in mice with deletion of the autism-associated Met receptor tyrosine kinase. J Neurosci (2011) 1.22
Mitochondrial dysfunction in autism spectrum disorders: cause or effect? Biochim Biophys Acta (2010) 1.18
Fetal mechanisms in neurodevelopmental disorders. Pediatr Neurol (2008) 1.18
Association of oxytocin receptor (OXTR) gene variants with multiple phenotype domains of autism spectrum disorder. J Neurodev Disord (2011) 1.17
Reelin is a serine protease of the extracellular matrix. J Biol Chem (2001) 1.16
Dynamic gene and protein expression patterns of the autism-associated met receptor tyrosine kinase in the developing mouse forebrain. J Comp Neurol (2009) 1.13
Genome-wide expression studies in autism spectrum disorder, Rett syndrome, and Down syndrome. Neurobiol Dis (2010) 1.11
Ethnic stratification of the association of RGS4 variants with antipsychotic treatment response in schizophrenia. Biol Psychiatry (2007) 1.10
Association between the HOXA1 A218G polymorphism and increased head circumference in patients with autism. Biol Psychiatry (2004) 1.10
Three-dimensional high-resolution diffusion tensor imaging and tractography of the developing rabbit brain. Dev Neurosci (2007) 1.10
Altered neocortical cell density and layer thickness in serotonin transporter knockout mice: a quantitation study. Cereb Cortex (2006) 1.10
Evidence of cell-nonautonomous changes in dendrite and dendritic spine morphology in the met-signaling-deficient mouse forebrain. J Comp Neurol (2010) 1.09
Principal pathogenetic components and biological endophenotypes in autism spectrum disorders. Autism Res (2010) 1.08
Genetic deletion of Lsamp causes exaggerated behavioral activation in novel environments. Behav Brain Res (2007) 1.07
Regulation of MET by FOXP2, genes implicated in higher cognitive dysfunction and autism risk. J Neurosci (2011) 1.07
Clinical, morphological, and biochemical correlates of head circumference in autism. Biol Psychiatry (2007) 1.06
DHCEO accumulation is a critical mediator of pathophysiology in a Smith-Lemli-Opitz syndrome model. Neurobiol Dis (2011) 1.05
Lipid biomarkers of oxidative stress in a genetic mouse model of Smith-Lemli-Opitz syndrome. J Inherit Metab Dis (2012) 1.04
The autism risk genes MET and PLAUR differentially impact cortical development. Autism Res (2010) 1.04
Anatomical abnormalities in dopaminoceptive regions of the cerebral cortex of dopamine D1 receptor mutant mice. J Comp Neurol (2005) 1.04
Multiple roles of ephrins during the formation of thalamocortical projections: maps and more. J Neurobiol (2004) 1.04
Regulator of G Signaling 16 is a marker for the distinct endoplasmic reticulum stress state associated with aggregated mutant alpha1-antitrypsin Z in the classical form of alpha1-antitrypsin deficiency. J Biol Chem (2007) 1.04
Immune system gene dysregulation in autism and schizophrenia. Dev Neurobiol (2012) 1.04
Altered expression of 14-3-3 genes in the prefrontal cortex of subjects with schizophrenia. Neuropsychopharmacology (2005) 1.03
Prenatal exposure to cocaine produces unique developmental and long-term adaptive changes in dopamine D1 receptor activity and subcellular distribution. J Neurosci (2007) 1.03
Gene expression profiling with DNA microarrays: advancing our understanding of psychiatric disorders. Neurochem Res (2002) 1.03
Metabolism of oxysterols derived from nonenzymatic oxidation of 7-dehydrocholesterol in cells. J Lipid Res (2013) 1.02
A role for presenilins in autophagy revisited: normal acidification of lysosomes in cells lacking PSEN1 and PSEN2. J Neurosci (2012) 1.02
Drug exposure early in life: functional repercussions of changing neuropharmacology during sensitive periods of brain development. Curr Opin Pharmacol (2004) 1.02
Age-dependent decrease and alternative splicing of methionine synthase mRNA in human cerebral cortex and an accelerated decrease in autism. PLoS One (2013) 1.02
Autism and 15q11-q13 disorders: behavioral, genetic, and pathophysiological issues. Ment Retard Dev Disabil Res Rev (2004) 1.01
Triggering endogenous neuroprotective processes through exercise in models of dopamine deficiency. Parkinsonism Relat Disord (2009) 1.01
The psychologist as an interlocutor in autism spectrum disorder assessment: insights from a study of spontaneous prosody. J Speech Lang Hear Res (2014) 1.01
Biomarkers in autism spectrum disorder: the old and the new. Psychopharmacology (Berl) (2013) 1.01
Prenatal cocaine exposure specifically alters spontaneous alternation behavior. Behav Brain Res (2005) 1.01
Genetic analysis of anterior posterior expression gradients in the developing mammalian forebrain. Cereb Cortex (2006) 1.00
Prenatal polycyclic aromatic hydrocarbon exposure leads to behavioral deficits and downregulation of receptor tyrosine kinase, MET. Toxicol Sci (2010) 1.00
Evaluation of a susceptibility gene for schizophrenia: genotype based meta-analysis of RGS4 polymorphisms from thirteen independent samples. Biol Psychiatry (2006) 1.00
A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease. Am J Hum Genet (2004) 0.99
Differential regulation of thalamic and cortical axonal growth by hepatocyte growth factor/scatter factor. Dev Neurosci (2003) 0.99
Serotonergic regulation of somatosensory cortical development: lessons from genetic mouse models. Dev Neurosci (2003) 0.99
Case-control and family-based association studies of candidate genes in autistic disorder and its endophenotypes: TPH2 and GLO1. BMC Med Genet (2007) 0.98
Region- and age-specific deficits in gamma-aminobutyric acidergic neuron development in the telencephalon of the uPAR(-/-) mouse. J Comp Neurol (2005) 0.97
Sex-specific, postpuberty changes in mouse brain structures revealed by three-dimensional magnetic resonance microscopy. Neuroimage (2004) 0.97
The neurobiological context of autism. Mol Neurobiol (2003) 0.97
Urinary p-cresol is elevated in small children with severe autism spectrum disorder. Biomarkers (2011) 0.97
Activation of the ciliary neurotrophic factor (CNTF) signalling pathway in cortical neurons of multiple sclerosis patients. Brain (2007) 0.96
Methodological factors influencing measurement and processing of plasma reelin in humans. BMC Biochem (2003) 0.95
Conserved subcortical and divergent cortical expression of proteins encoded by orthologs of the autism risk gene MET. Cereb Cortex (2010) 0.95
Association of RGS2 and RGS5 variants with schizophrenia symptom severity. Schizophr Res (2008) 0.94