Published in BMC Med on October 22, 2009
Rethinking schizophrenia. Nature (2010) 4.85
The challenge of translation in social neuroscience: a review of oxytocin, vasopressin, and affiliative behavior. Neuron (2010) 3.56
Validation of proposed DSM-5 criteria for autism spectrum disorder. J Am Acad Child Adolesc Psychiatry (2011) 2.72
Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy. Nat Rev Drug Discov (2012) 2.44
Autism, oxytocin and interoception. Neurosci Biobehav Rev (2014) 1.88
Transgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptor. Transl Psychiatry (2011) 1.85
Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits. Mol Psychiatry (2013) 1.60
D-cycloserine facilitates socially reinforced learning in an animal model relevant to autism spectrum disorders. Biol Psychiatry (2011) 1.55
The oxytocin system in drug discovery for autism: animal models and novel therapeutic strategies. Horm Behav (2011) 1.51
Oxytocin receptor gene (OXTR) is related to psychological resources. Proc Natl Acad Sci U S A (2011) 1.46
Metabolic imbalance associated with methylation dysregulation and oxidative damage in children with autism. J Autism Dev Disord (2012) 1.38
Large-scale methylation domains mark a functional subset of neuronally expressed genes. Genome Res (2011) 1.34
Intranasal oxytocin versus placebo in the treatment of adults with autism spectrum disorders: a randomized controlled trial. Mol Autism (2012) 1.30
Epigenetics meets endocrinology. J Mol Endocrinol (2011) 1.30
Aerosolized oxytocin increases cerebrospinal fluid oxytocin in rhesus macaques. Psychoneuroendocrinology (2014) 1.26
Social 'wanting' dysfunction in autism: neurobiological underpinnings and treatment implications. J Neurodev Disord (2012) 1.21
The role of oxytocin in psychiatric disorders: a review of biological and therapeutic research findings. Harv Rev Psychiatry (2014) 1.18
Dynamic changes in DNA methylation of stress-associated genes (OXTR, BDNF ) after acute psychosocial stress. Transl Psychiatry (2012) 1.17
Oxytocin and social motivation. Dev Cogn Neurosci (2011) 1.17
Nasal oxytocin for social deficits in childhood autism: a randomized controlled trial. J Autism Dev Disord (2014) 1.16
Social attention: a possible early indicator of efficacy in autism clinical trials. J Neurodev Disord (2012) 1.14
Brain transcriptional and epigenetic associations with autism. PLoS One (2012) 1.13
Complex epigenetic regulation of engrailed-2 (EN-2) homeobox gene in the autism cerebellum. Transl Psychiatry (2013) 1.12
Absence of preference for social novelty and increased grooming in integrin β3 knockout mice: initial studies and future directions. Autism Res (2011) 1.11
Examining autism spectrum disorders by biomarkers: example from the oxytocin and serotonin systems. J Am Acad Child Adolesc Psychiatry (2012) 1.09
DNA methylation of the oxytocin receptor gene predicts neural response to ambiguous social stimuli. Front Hum Neurosci (2012) 1.08
Epigenetic regulation of the oxytocin receptor gene: implications for behavioral neuroscience. Front Neurosci (2013) 1.08
Association between oxytocin receptor gene polymorphisms and self-rated 'empathic concern' in schizophrenia. PLoS One (2012) 1.06
Autism and oxytocin: new developments in translational approaches to therapeutics. Neurotherapeutics (2010) 1.05
Novel region discovery method for Infinium 450K DNA methylation data reveals changes associated with aging in muscle and neuronal pathways. Aging Cell (2013) 1.05
Increasing oxytocin receptor expression in the nucleus accumbens of pre-pubertal female prairie voles enhances alloparental responsiveness and partner preference formation as adults. Horm Behav (2011) 1.04
Age-dependent decrease and alternative splicing of methionine synthase mRNA in human cerebral cortex and an accelerated decrease in autism. PLoS One (2013) 1.02
Effects of a common variant in the CD38 gene on social processing in an oxytocin challenge study: possible links to autism. Neuropsychopharmacology (2012) 1.00
Research review: Social motivation and oxytocin in autism--implications for joint attention development and intervention. J Child Psychol Psychiatry (2013) 1.00
A genomic point-of-view on environmental factors influencing the human brain methylome. Epigenetics (2011) 1.00
Epigenetic dysregulation of SHANK3 in brain tissues from individuals with autism spectrum disorders. Hum Mol Genet (2013) 0.99
Implications of prenatal steroid perturbations for neurodevelopment, behavior, and autism. Endocr Rev (2014) 0.97
A twin study of heritable and shared environmental contributions to autism. J Autism Dev Disord (2014) 0.95
DNA methylation of specific CpG sites in the promoter region regulates the transcription of the mouse oxytocin receptor. PLoS One (2013) 0.95
Epigenetic modification of the oxytocin receptor gene influences the perception of anger and fear in the human brain. Proc Natl Acad Sci U S A (2015) 0.95
The Role of Epigenetic Change in Autism Spectrum Disorders. Front Neurol (2015) 0.95
Oxytocin and vasopressin are dysregulated in Williams Syndrome, a genetic disorder affecting social behavior. PLoS One (2012) 0.94
All-trans retinoic acid upregulates reduced CD38 transcription in lymphoblastoid cell lines from Autism spectrum disorder. Mol Med (2011) 0.93
Biomarkers in autism. Front Psychiatry (2014) 0.92
Environmental risk, Oxytocin Receptor Gene (OXTR) methylation and youth callous-unemotional traits: a 13-year longitudinal study. Mol Psychiatry (2014) 0.90
Epigenomic strategies at the interface of genetic and environmental risk factors for autism. J Hum Genet (2013) 0.90
ZNF277 microdeletions, specific language impairment and the meiotic mismatch methylation (3M) hypothesis. Eur J Hum Genet (2014) 0.90
Developmental perspectives on oxytocin and vasopressin. Neuropsychopharmacology (2014) 0.88
Variation in the Oxytocin Receptor Gene Predicts Brain Region-Specific Expression and Social Attachment. Biol Psychiatry (2015) 0.88
Antiaggressive activity of central oxytocin in male rats. Psychopharmacology (Berl) (2013) 0.87
Performance comparison of bench-top next generation sequencers using microdroplet PCR-based enrichment for targeted sequencing in patients with autism spectrum disorder. PLoS One (2013) 0.86
Oxytocin receptor knockout mice display deficits in the expression of autism-related behaviors. Horm Behav (2011) 0.86
Oxytocin receptor gene methylation: converging multilevel evidence for a role in social anxiety. Neuropsychopharmacology (2015) 0.85
Investigation of an F-18 oxytocin receptor selective ligand via PET imaging. Bioorg Med Chem Lett (2013) 0.85
Imaging-genetics in autism spectrum disorder: advances, translational impact, and future directions. Front Psychiatry (2012) 0.85
Toward a radically embodied neuroscience of attachment and relationships. Front Hum Neurosci (2015) 0.85
Evidence of novel fine-scale structural variation at autism spectrum disorder candidate loci. Mol Autism (2012) 0.84
A deletion involving CD38 and BST1 results in a fusion transcript in a patient with autism and asthma. Autism Res (2014) 0.84
RNAi knockdown of oxytocin receptor in the nucleus accumbens inhibits social attachment and parental care in monogamous female prairie voles. Soc Neurosci (2015) 0.84
Annual Research Review: Transgenic mouse models of childhood-onset psychiatric disorders. J Child Psychol Psychiatry (2011) 0.84
Differential methylation of the oxytocin receptor gene in patients with anorexia nervosa: a pilot study. PLoS One (2014) 0.84
Variation in the oxytocin receptor gene is associated with increased risk for anxiety, stress and depression in individuals with a history of exposure to early life stress. J Psychiatr Res (2014) 0.84
Plasma Oxytocin in Children with Autism and Its Correlations with Behavioral Parameters in Children and Parents. Psychiatry Investig (2016) 0.84
Natural variation in maternal care and cross-tissue patterns of oxytocin receptor gene methylation in rats. Horm Behav (2015) 0.83
Peripartum depression and anxiety as an integrative cross domain target for psychiatric preventative measures. Behav Brain Res (2014) 0.83
Cumulative risk on the oxytocin receptor gene (OXTR) underpins empathic communication difficulties at the first stages of romantic love. Soc Cogn Affect Neurosci (2013) 0.83
Epigenetic Regulation of Infant Neurobehavioral Outcomes. Med Epigenet (2014) 0.83
The EPIIC hypothesis: intrapartum effects on the neonatal epigenome and consequent health outcomes. Med Hypotheses (2013) 0.83
Comparative Perspectives on Oxytocin and Vasopressin Receptor Research in Rodents and Primates: Translational Implications. J Neuroendocrinol (2016) 0.83
Non-synonymous single-nucleotide variations of the human oxytocin receptor gene and autism spectrum disorders: a case-control study in a Japanese population and functional analysis. Mol Autism (2013) 0.83
Evidence for alterations in stimulatory G proteins and oxytocin levels in children with autism. Psychoneuroendocrinology (2013) 0.83
From Autism to Eating Disorders and More: The Role of Oxytocin in Neuropsychiatric Disorders. Front Neurosci (2016) 0.83
Progress in understanding autism: 2007-2010. J Autism Dev Disord (2011) 0.82
Carbon-11 N-methyl alkylation of L-368,899 and in vivo PET imaging investigations for neural oxytocin receptors. Bioorg Med Chem Lett (2012) 0.82
Neurobiology of sociability. Adv Exp Med Biol (2012) 0.82
Epigenetics and autism. Autism Res Treat (2013) 0.81
Association between the oxytocin receptor (OXTR) gene and mesolimbic responses to rewards. Mol Autism (2014) 0.81
Genetic variation in the oxytocin receptor (OXTR) gene is associated with Asperger Syndrome. Mol Autism (2014) 0.81
From genes to environment: using integrative genomics to build a "systems-level" understanding of autism spectrum disorders. Child Dev (2012) 0.81
Autism as early neurodevelopmental disorder: evidence for an sAPPα-mediated anabolic pathway. Front Cell Neurosci (2013) 0.81
Neuroscience: In their nurture. Nature (2010) 0.81
Interaction between oxytocin receptor DNA methylation and genotype is associated with risk of postpartum depression in women without depression in pregnancy. Front Genet (2015) 0.81
Genes Related to Oxytocin and Arginine-Vasopressin Pathways: Associations with Autism Spectrum Disorders. Neurosci Bull (2017) 0.81
Mothers of autistic children: lower plasma levels of oxytocin and Arg-vasopressin and a higher level of testosterone. PLoS One (2013) 0.80
Defective oxytocin function: a clue to understanding the cause of autism? BMC Med (2009) 0.80
Genome-wide analysis of DNA methylation in human amnion. ScientificWorldJournal (2013) 0.80
Using genetic findings in autism for the development of new pharmaceutical compounds. Psychopharmacology (Berl) (2013) 0.80
The effects of birth order and birth interval on the phenotypic expression of autism spectrum disorder. PLoS One (2012) 0.79
Oxytocin and vasopressin: linking pituitary neuropeptides and their receptors to social neurocircuits. Front Neurosci (2015) 0.79
Genetic modulation of oxytocin sensitivity: a pharmacogenetic approach. Transl Psychiatry (2015) 0.79
Oxytocin Receptor Genetic and Epigenetic Variations: Association With Child Abuse and Adult Psychiatric Symptoms. Child Dev (2016) 0.79
Beyond labor: the role of natural and synthetic oxytocin in the transition to motherhood. J Midwifery Womens Health (2014) 0.79
Lower neighborhood quality in adolescence predicts higher mesolimbic sensitivity to reward anticipation in adulthood. Dev Cogn Neurosci (2016) 0.79
DNA methylation patterns of behavior-related gene promoter regions dissect the gray wolf from domestic dog breeds. Mol Genet Genomics (2017) 0.78
Placental methylome analysis from a prospective autism study. Mol Autism (2016) 0.78
Early social environment affects the endogenous oxytocin system: a review and future directions. Front Endocrinol (Lausanne) (2015) 0.78
Glutamatergic candidate genes in autism spectrum disorder: an overview. J Neural Transm (Vienna) (2014) 0.78
Oxytocin, vasopressin, and Williams syndrome: epigenetic effects on abnormal social behavior. Front Genet (2015) 0.78
Genetics of Autism Spectrum Disorder: Current Status and Possible Clinical Applications. Exp Neurobiol (2015) 0.78
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
Detection of large-scale variation in the human genome. Nat Genet (2004) 49.18
Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord (1994) 42.80
Large-scale copy number polymorphism in the human genome. Science (2004) 34.64
Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. J Mol Endocrinol (2000) 29.28
Strong association of de novo copy number mutations with autism. Science (2007) 27.84
Circular binary segmentation for the analysis of array-based DNA copy number data. Biostatistics (2004) 24.18
Epigenetic programming by maternal behavior. Nat Neurosci (2004) 20.92
Association between microdeletion and microduplication at 16p11.2 and autism. N Engl J Med (2008) 19.71
Structural variation of chromosomes in autism spectrum disorder. Am J Hum Genet (2008) 15.51
Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet (2007) 14.05
Advances in autism genetics: on the threshold of a new neurobiology. Nat Rev Genet (2008) 12.18
Prevalence of autism in a US metropolitan area. JAMA (2003) 10.37
Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. Nature (2009) 9.47
Common genetic variants on 5p14.1 associate with autism spectrum disorders. Nature (2009) 7.39
Genetics of autism: complex aetiology for a heterogeneous disorder. Nat Rev Genet (2001) 5.91
The genetics of autism. Pediatrics (2004) 4.93
DNA microarrays for comparative genomic hybridization based on DOP-PCR amplification of BAC and PAC clones. Genes Chromosomes Cancer (2003) 4.68
Social amnesia in mice lacking the oxytocin gene. Nat Genet (2000) 4.52
Autism or atypical autism in maternally but not paternally derived proximal 15q duplication. Am J Hum Genet (1997) 3.95
Genome-wide scan for autism susceptibility genes. Paris Autism Research International Sibpair Study. Hum Mol Genet (1999) 3.93
A full genome screen for autism with evidence for linkage to a region on chromosome 7q. International Molecular Genetic Study of Autism Consortium. Hum Mol Genet (1998) 3.63
A unified genetic theory for sporadic and inherited autism. Proc Natl Acad Sci U S A (2007) 3.47
Diagnosing autism: analyses of data from the Autism Diagnostic Interview. J Autism Dev Disord (1997) 3.45
Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice. Proc Natl Acad Sci U S A (2005) 2.84
Positive association of the oxytocin receptor gene (OXTR) with autism in the Chinese Han population. Biol Psychiatry (2005) 2.79
Chromosomal disorders and autism. J Autism Dev Disord (1998) 2.62
Oxytocin receptor distribution reflects social organization in monogamous and polygamous voles. Proc Natl Acad Sci U S A (1992) 2.60
Association of the oxytocin receptor gene (OXTR) in Caucasian children and adolescents with autism. Neurosci Lett (2007) 2.38
Autistic symptoms among children and young adults with isodicentric chromosome 15. Am J Med Genet (1998) 2.38
Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation. Epigenetics (2007) 2.30
Fine mapping of autistic disorder to chromosome 15q11-q13 by use of phenotypic subtypes. Am J Hum Genet (2003) 2.23
Sex differences in oxytocin and vasopressin: implications for autism spectrum disorders? Behav Brain Res (2006) 2.18
Autism and maternally derived aberrations of chromosome 15q. Am J Med Genet (1998) 2.16
Identification of MeCP2 mutations in a series of females with autistic disorder. Pediatr Neurol (2003) 2.14
Association between the oxytocin receptor (OXTR) gene and autism: relationship to Vineland Adaptive Behavior Scales and cognition. Mol Psychiatry (2007) 2.10
Disruption of cerebral cortex MET signaling in autism spectrum disorder. Ann Neurol (2007) 2.02
Oxytocin--a neuropeptide for affiliation: evidence from behavioral, receptor autoradiographic, and comparative studies. Psychoneuroendocrinology (1992) 1.96
Sex differences in pervasive developmental disorders. J Autism Dev Disord (1993) 1.93
Linkage-disequilibrium mapping of autistic disorder, with 15q11-13 markers. Am J Hum Genet (1998) 1.87
Diffusion tensor imaging of white matter in the superior temporal gyrus and temporal stem in autism. Neurosci Lett (2007) 1.84
Autism, affective and other psychiatric disorders: patterns of familial aggregation. Psychol Med (1998) 1.74
Abnormal regional cerebral blood flow in childhood autism. Brain (2000) 1.69
Duplication of the 15q11-13 region in a patient with autism, epilepsy and ataxia. Dev Med Child Neurol (1994) 1.63
Sex differences in higher functioning people with autism. J Autism Dev Disord (1993) 1.61
Search for autism loci by combined analysis of Autism Genetic Resource Exchange and Finnish families. Ann Neurol (2006) 1.57
The social deficits of the oxytocin knockout mouse. Neuropeptides (2002) 1.54
Genome-wide and Ordered-Subset linkage analyses provide support for autism loci on 17q and 19p with evidence of phenotypic and interlocus genetic correlates. BMC Med Genet (2005) 1.44
Brief report: duplication of chromosome 15q11-13 in two individuals with autistic disorder. J Autism Dev Disord (1994) 1.31
The broad autism phenotype: findings from an epidemiological survey. Autism (2004) 1.30
Mitochondrial dysfunction in autistic patients with 15q inverted duplication. Ann Neurol (2003) 1.30
Epigenetic mechanisms for nutrition determinants of later health outcomes. Am J Clin Nutr (2009) 1.28
Perception of complex sounds: abnormal pattern of cortical activation in autism. Am J Psychiatry (2003) 1.25
Central oxytocin and reproductive behaviours. Rev Reprod (1997) 1.20
Interstitial duplications of chromosome region 15q11q13: clinical and molecular characterization. Am J Med Genet (1998) 1.19
DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation. Cancer Res (2008) 1.17
Linkage disequilibrium at the Angelman syndrome gene UBE3A in autism families. Genomics (2001) 1.17
Temporal lobe dysfunction in childhood autism: a PET study. Positron emission tomography. Am J Psychiatry (2000) 1.17
DNA methylation of the human oxytocin receptor gene promoter regulates tissue-specific gene suppression. Biochem Biophys Res Commun (2001) 1.14
A genomic element within the third intron of the human oxytocin receptor gene may be involved in transcriptional suppression. Mol Cell Endocrinol (1997) 1.13
Infantile hypotonia as a presentation of Rett syndrome. Am J Med Genet (2002) 1.13
Autism in tuberous sclerosis complex. J Autism Dev Disord (1998) 1.12
Cytogenetic and molecular analysis of inv dup(15) chromosomes observed in two patients with autistic disorder and mental retardation. Am J Med Genet (1996) 1.12
Morphological study of neocortical areas in Rett syndrome. Acta Neuropathol (1997) 1.10
Infantile autism and associated autosomal chromosome abnormalities: a register-based study and a literature survey. J Child Psychol Psychiatry (1999) 1.08
Genetic and clinical characterization of patients with an interstitial duplication 15q11-q13, emphasizing behavioral phenotype and response to treatment. Am J Med Genet A (2003) 1.06
Involvement of the PRKCB1 gene in autistic disorder: significant genetic association and reduced neocortical gene expression. Mol Psychiatry (2008) 1.03
A family with a grand-maternally derived interstitial duplication of proximal 15q. Clin Genet (2001) 1.02
A case of autism associated with partial tetrasomy 15. J Autism Dev Disord (1995) 0.97
Molecular regulation of the oxytocin receptor in peripheral organs. J Mol Endocrinol (2003) 0.90
Behavioral comparisons in autistic individuals from multiplex and singleton families. J Autism Dev Disord (2003) 0.87
The syndrome of inv dup (15): clinical, electroencephalographic, and imaging findings. J Child Neurol (2000) 0.87
Tetrasomy 15q11-q13 identified by fluorescence in situ hybridization in a patient with autistic disorder. Arq Neuropsiquiatr (2002) 0.87
Pervasive developmental disorder and epilepsy due to maternally derived duplication of 15q11-q13. Neurology (1999) 0.85
The role of neurohypophyseal peptides in the central mediation of complex social processes--evidence from comparative studies. Regul Pept (1993) 0.83
Toward DSM-IV: a developmental approach to autistic disorder. Psychiatr Clin North Am (1991) 0.81
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
Complement factor H variant increases the risk of age-related macular degeneration. Science (2005) 17.95
Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med (2007) 17.06
Functional impact of global rare copy number variation in autism spectrum disorders. Nature (2010) 14.66
Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet (2007) 14.05
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biol (2008) 7.95
Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A. Nat Genet (2004) 7.45
Common genetic variants on 5p14.1 associate with autism spectrum disorders. Nature (2009) 7.39
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet (2009) 7.16
A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis. Science (2005) 7.03
Clinical and biological implications of driver mutations in myelodysplastic syndromes. Blood (2013) 6.50
The landscape of histone modifications across 1% of the human genome in five human cell lines. Genome Res (2007) 5.67
Accurate and reliable high-throughput detection of copy number variation in the human genome. Genome Res (2006) 5.50
Negotiating for change. The healthcare manager as catalyst for evidence-based practice: changing the healthcare environment and sharing experience. Healthc Pap (2003) 5.49
A 3.9-centimorgan-resolution human single-nucleotide polymorphism linkage map and screening set. Am J Hum Genet (2003) 5.34
Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nat Genet (2007) 5.09
450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy. Environ Health Perspect (2012) 4.89
No gene is an island: the flip-flop phenomenon. Am J Hum Genet (2007) 4.69
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet (2013) 4.62
Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia. Nature (2011) 4.56
Barriers to participation in clinical trials of cancer: a meta-analysis and systematic review of patient-reported factors. Lancet Oncol (2006) 4.32
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci U S A (2010) 4.30
Seven new loci associated with age-related macular degeneration. Nat Genet (2013) 3.81
Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles. Nat Genet (2012) 3.77
Randomized phase III trial comparing irinotecan/cisplatin with etoposide/cisplatin in patients with previously untreated extensive-stage disease small-cell lung cancer. J Clin Oncol (2006) 3.71
A HaemAtlas: characterizing gene expression in differentiated human blood cells. Blood (2009) 3.63
FRT-seq: amplification-free, strand-specific transcriptome sequencing. Nat Methods (2010) 3.55
Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease. Am J Hum Genet (2009) 3.54
A genome-wide scan for common alleles affecting risk for autism. Hum Mol Genet (2010) 3.42
Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease. Am J Hum Genet (2003) 3.39
Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis. Hum Mol Genet (2006) 3.13
A kinesin heavy chain (KIF5A) mutation in hereditary spastic paraplegia (SPG10). Am J Hum Genet (2002) 2.98
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol (2010) 2.91
Age at onset in two common neurodegenerative diseases is genetically controlled. Am J Hum Genet (2002) 2.90
Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration. Am J Hum Genet (2006) 2.89
Immune transcriptome alterations in the temporal cortex of subjects with autism. Neurobiol Dis (2008) 2.88
Mutations in the pleckstrin homology domain of dynamin 2 cause dominant intermediate Charcot-Marie-Tooth disease. Nat Genet (2005) 2.79
Clustering of autoimmune diseases in families with a high-risk for multiple sclerosis: a descriptive study. Lancet Neurol (2006) 2.77
Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans. Am J Hum Genet (2003) 2.71
Genomic screen and follow-up analysis for autistic disorder. Am J Med Genet (2002) 2.70
Evidence for polygenic susceptibility to multiple sclerosis--the shape of things to come. Am J Hum Genet (2010) 2.64
Age-related maculopathy: a genomewide scan with continued evidence of susceptibility loci within the 1q31, 10q26, and 17q25 regions. Am J Hum Genet (2004) 2.58
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. JAMA (2013) 2.58
A high-density screen for linkage in multiple sclerosis. Am J Hum Genet (2005) 2.50
Exome sequencing of a multigenerational human pedigree. PLoS One (2009) 2.48
Individual common variants exert weak effects on the risk for autism spectrum disorderspi. Hum Mol Genet (2012) 2.46
Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease. Hepatology (2013) 2.42
Outcome of ANCA-associated renal vasculitis: a 5-year retrospective study. Am J Kidney Dis (2003) 2.40
The role of the CD58 locus in multiple sclerosis. Proc Natl Acad Sci U S A (2009) 2.38
Analysis of European mitochondrial haplogroups with Alzheimer disease risk. Neurosci Lett (2004) 2.36
Meta-analysis of genome scans of age-related macular degeneration. Hum Mol Genet (2005) 2.34
PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice. Science (2010) 2.31
Gene expression profiles of CD34+ cells in myelodysplastic syndromes: involvement of interferon-stimulated genes and correlation to FAB subtype and karyotype. Blood (2006) 2.29
Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer. J Clin Oncol (2005) 2.25
Exercise prevents maternal high-fat diet-induced hypermethylation of the Pgc-1α gene and age-dependent metabolic dysfunction in the offspring. Diabetes (2014) 2.24
Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants. PLoS Genet (2012) 2.23
A genome-wide association study of autism reveals a common novel risk locus at 5p14.1. Ann Hum Genet (2009) 2.15
SNPselector: a web tool for selecting SNPs for genetic association studies. Bioinformatics (2005) 2.14
Identification of MeCP2 mutations in a series of females with autistic disorder. Pediatr Neurol (2003) 2.14
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Neuron (2013) 2.13
Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology (2012) 2.08
SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk. Ann Neurol (2011) 2.01
Parkin mutations and susceptibility alleles in late-onset Parkinson's disease. Ann Neurol (2003) 2.01
Mutations in the novel mitochondrial protein REEP1 cause hereditary spastic paraplegia type 31. Am J Hum Genet (2006) 2.00
A second major histocompatibility complex susceptibility locus for multiple sclerosis. Ann Neurol (2007) 1.99
Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease. Hum Mol Genet (2003) 1.98
Comprehensive search for Alzheimer disease susceptibility loci in the APOE region. Arch Neurol (2012) 1.97
Factor analysis of restricted and repetitive behaviors in autism using the Autism Diagnostic Interview-R. Child Psychiatry Hum Dev (2003) 1.97
Bone density and metabolism in children and adolescents with moderate to severe cerebral palsy. Pediatrics (2002) 1.93
Identification of the single base change causing the callipyge muscle hypertrophy phenotype, the only known example of polar overdominance in mammals. Genome Res (2002) 1.91
Integrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes. Oncotarget (2010) 1.88
Linkage disequilibrium inflates type I error rates in multipoint linkage analysis when parental genotypes are missing. Hum Hered (2005) 1.86
A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study. Am J Hum Genet (2003) 1.85
Deletion of CFHR3 and CFHR1 genes in age-related macular degeneration. Hum Mol Genet (2007) 1.83
Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities. PLoS Genet (2010) 1.80
Comparing age-related macular degeneration phenotype in probands from singleton and multiplex families. Am J Ophthalmol (2005) 1.73
Fracture rate in children with cerebral palsy. Pediatr Rehabil (2006) 1.72
Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice. Nat Genet (2011) 1.71