PubRank

John S Condeelis

Author PubWeight™ 88.07‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cofilin promotes actin polymerization and defines the direction of cell motility. Science 2004 5.12
2 Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop. Cancer Res 2005 4.33
3 Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors. Cancer Res 2004 4.04
4 Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling. Cancer Res 2002 3.95
5 Chemotaxis in cancer. Nat Rev Cancer 2011 3.68
6 ROCK- and myosin-dependent matrix deformation enables protease-independent tumor-cell invasion in vivo. Curr Biol 2006 3.55
7 An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype. PLoS Genet 2011 2.99
8 A Mena invasion isoform potentiates EGF-induced carcinoma cell invasion and metastasis. Dev Cell 2008 2.65
9 The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors. J Cell Biol 2006 2.59
10 EGF-induced PIP2 hydrolysis releases and activates cofilin locally in carcinoma cells. J Cell Biol 2007 2.48
11 Tumor microenvironment of metastasis in human breast carcinoma: a potential prognostic marker linked to hematogenous dissemination. Clin Cancer Res 2009 2.41
12 Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function. Proc Natl Acad Sci U S A 2012 2.29
13 Invasion of human breast cancer cells in vivo requires both paracrine and autocrine loops involving the colony-stimulating factor-1 receptor. Cancer Res 2009 2.25
14 Coordinated regulation of pathways for enhanced cell motility and chemotaxis is conserved in rat and mouse mammary tumors. Cancer Res 2007 2.24
15 Tumor cells caught in the act of invading: their strategy for enhanced cell motility. Trends Cell Biol 2005 2.04
16 Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer. J Cell Sci 2011 2.00
17 GFP expression in the mammary gland for imaging of mammary tumor cells in transgenic mice. Cancer Res 2002 1.77
18 A photoswitchable orange-to-far-red fluorescent protein, PSmOrange. Nat Methods 2011 1.69
19 Molecular cloning of hMena (ENAH) and its splice variant hMena+11a: epidermal growth factor increases their expression and stimulates hMena+11a phosphorylation in breast cancer cell lines. Cancer Res 2007 1.65
20 Gene expression analysis of macrophages that facilitate tumor invasion supports a role for Wnt-signaling in mediating their activity in primary mammary tumors. J Immunol 2009 1.64
21 Identification of invasion specific splice variants of the cytoskeletal protein Mena present in mammary tumor cells during invasion in vivo. Clin Exp Metastasis 2008 1.64
22 Initiation of cofilin activity in response to EGF is uncoupled from cofilin phosphorylation and dephosphorylation in carcinoma cells. J Cell Sci 2006 1.55
23 Differential enhancement of breast cancer cell motility and metastasis by helical and kinase domain mutations of class IA phosphoinositide 3-kinase. Cancer Res 2009 1.45
24 Selective gene-expression profiling of migratory tumor cells in vivo predicts clinical outcome in breast cancer patients. Breast Cancer Res 2012 1.43
25 The distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migration. J Cell Sci 2007 1.34
26 Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis. Breast Cancer Res 2011 1.33
27 Mechanisms and cellular roles of local protein synthesis in mammalian cells. Curr Opin Cell Biol 2008 1.31
28 Breast cancer cells isolated by chemotaxis from primary tumors show increased survival and resistance to chemotherapy. Cancer Res 2004 1.31
29 Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors. Breast Cancer Res 2010 1.24
30 Mena invasive (Mena(INV)) and Mena11a isoforms play distinct roles in breast cancer cell cohesion and association with TMEM. Clin Exp Metastasis 2011 1.23
31 RhoA/ROCK-mediated switching between Cdc42- and Rac1-dependent protrusion in MTLn3 carcinoma cells. Exp Cell Res 2008 1.22
32 AACR special conference on epithelial-mesenchymal transition and cancer progression and treatment. Cancer Res 2010 1.17
33 ZBP1 enhances cell polarity and reduces chemotaxis. J Cell Sci 2007 1.11
34 Reconstitution of in vivo macrophage-tumor cell pairing and streaming motility on one-dimensional micro-patterned substrates. Intravital 2012 1.10
35 Cdc42 is required for EGF-stimulated protrusion and motility in MTLn3 carcinoma cells. J Cell Sci 2007 1.07
36 Gene expression analysis on small numbers of invasive cells collected by chemotaxis from primary mammary tumors of the mouse. BMC Biotechnol 2003 1.05
37 A new chemotaxis device for cell migration studies. Integr Biol (Camb) 2010 1.04
38 Filamin A interacting protein 1-like inhibits WNT signaling and MMP expression to suppress cancer cell invasion and metastasis. Int J Cancer 2014 0.98
39 Quantitative assessment of invasive mena isoforms (Menacalc) as an independent prognostic marker in breast cancer. Breast Cancer Res 2012 0.96
40 Wiskott-Aldrich syndrome protein regulates leukocyte-dependent breast cancer metastasis. Cell Rep 2013 0.92
41 Over-expression of the p110beta but not p110alpha isoform of PI 3-kinase inhibits motility in breast cancer cells. Cell Motil Cytoskeleton 2004 0.91
42 A new strategy for caging proteins regulated by kinases. J Am Chem Soc 2002 0.86
43 A FRET-facilitated photoswitching using an orange fluorescent protein with the fast photoconversion kinetics. J Am Chem Soc 2012 0.86
44 An in vitro one-dimensional assay to study growth factor-regulated tumor cell-macrophage interaction. Methods Mol Biol 2014 0.86
45 Dysregulation of PAD4-mediated citrullination of nuclear GSK3β activates TGF-β signaling and induces epithelial-to-mesenchymal transition in breast cancer cells. Proc Natl Acad Sci U S A 2013 0.85
46 Metastatic cells: moving onco-targets. Oncotarget 2014 0.78
47 Imaging real-time gene expression in living yeast. CSH Protoc 2007 0.77
48 Correlated immunohistochemical and cytological assays for the prediction of hematogenous dissemination of breast cancer. J Histochem Cytochem 2012 0.76
49 Imaging real-time gene expression in living systems with single-transcript resolution: image analysis of single mRNA transcripts. CSH Protoc 2007 0.75
50 Imaging real-time gene expression in living systems with single-transcript resolution: construct design and imaging system setup. CSH Protoc 2007 0.75
51 Imaging real-time gene expression in Mammalian cells with single-transcript resolution. CSH Protoc 2007 0.75
52 3-D individual cell based computational modeling of tumor cell-macrophage paracrine signaling mediated by EGF and CSF-1 gradients. Integr Biol (Camb) 2015 0.75
53 Imaging Real-Time Gene Expression in Living Systems with Single-Transcript Resolution: Single mRNA Particle Tracking with ImageJ-Based Analysis. CSH Protoc 2007 0.75