Published in Science on August 17, 2007
Translational control of long-lasting synaptic plasticity and memory. Neuron (2009) 4.77
A memory retrieval-extinction procedure to prevent drug craving and relapse. Science (2012) 4.04
PKMzeta maintains spatial, instrumental, and classically conditioned long-term memories. PLoS Biol (2008) 2.58
How does PKMζ maintain long-term memory? Nat Rev Neurosci (2010) 2.47
PKMzeta maintains memories by regulating GluR2-dependent AMPA receptor trafficking. Nat Neurosci (2010) 2.28
PKM-ζ is not required for hippocampal synaptic plasticity, learning and memory. Nature (2013) 2.26
PKM zeta maintains late long-term potentiation by N-ethylmaleimide-sensitive factor/GluR2-dependent trafficking of postsynaptic AMPA receptors. J Neurosci (2008) 2.26
Prkcz null mice show normal learning and memory. Nature (2013) 2.06
Targeting extinction and reconsolidation mechanisms to combat the impact of drug cues on addiction. Neuropharmacology (2008) 1.84
Epigenetic principles and mechanisms underlying nervous system functions in health and disease. Prog Neurobiol (2008) 1.53
Visual experience induces long-term potentiation in the primary visual cortex. J Neurosci (2010) 1.43
Inhibition of PKMzeta in nucleus accumbens core abolishes long-term drug reward memory. J Neurosci (2011) 1.40
The cell biology of synaptic plasticity. Science (2011) 1.37
Modelling the molecular mechanisms of synaptic plasticity using systems biology approaches. Nat Rev Neurosci (2010) 1.32
Spinal protein kinase M ζ underlies the maintenance mechanism of persistent nociceptive sensitization. J Neurosci (2011) 1.30
Protein kinase Mzeta maintains fear memory in the amygdala but not in the hippocampus. Behav Neurosci (2009) 1.28
Protein kinase C pharmacology: refining the toolbox. Biochem J (2013) 1.27
Temporary disruption of fear-potentiated startle following PKMζ inhibition in the amygdala. Nat Neurosci (2011) 1.23
Boundary conditions for the maintenance of memory by PKMzeta in neocortex. Learn Mem (2009) 1.22
Cellular pharmacology of protein kinase Mζ (PKMζ) contrasts with its in vitro profile: implications for PKMζ as a mediator of memory. J Biol Chem (2012) 1.21
PKMζ maintains drug reward and aversion memory in the basolateral amygdala and extinction memory in the infralimbic cortex. Neuropsychopharmacology (2011) 1.16
Cognitive neuroepigenetics: a role for epigenetic mechanisms in learning and memory. Neurobiol Learn Mem (2010) 1.16
Wnt transmembrane signaling and long-term spatial memory. Hippocampus (2011) 1.14
Learning to forget: manipulating extinction and reconsolidation processes to treat addiction. Psychopharmacology (Berl) (2012) 1.09
KIBRA: A New Gateway to Learning and Memory? Front Aging Neurosci (2010) 1.09
The atypical protein kinase C in Aplysia can form a protein kinase M by cleavage. J Neurochem (2009) 1.09
Neural population-level memory traces in the mouse hippocampus. PLoS One (2009) 1.08
Role of protein kinase C in the induction and maintenance of serotonin-dependent enhancement of the glutamate response in isolated siphon motor neurons of Aplysia californica. J Neurosci (2009) 1.08
Drosophila Orb2 targets genes involved in neuronal growth, synapse formation, and protein turnover. Proc Natl Acad Sci U S A (2010) 1.08
The ubiquitin-proteasome system as a critical regulator of synaptic plasticity and long-term memory formation. Neurobiol Learn Mem (2013) 1.07
Proteolysis of proBDNF is a key regulator in the formation of memory. PLoS One (2008) 1.07
Protein kinase C-dependent and independent signaling pathways regulate synaptic GluR1 and GluR4 AMPAR subunits during in vitro classical conditioning. Neuroscience (2008) 1.07
TrkB and protein kinase Mζ regulate synaptic localization of PSD-95 in developing cortex. J Neurosci (2011) 1.04
AMPA receptor trafficking and the mechanisms underlying synaptic plasticity and cognitive aging. Dialogues Clin Neurosci (2013) 1.04
Inducible and selective erasure of memories in the mouse brain via chemical-genetic manipulation. Neuron (2008) 1.04
How to erase memory traces of pain and fear. Trends Neurosci (2013) 1.03
PKMzeta inhibition reverses learning-induced increases in hippocampal synaptic strength and memory during trace eyeblink conditioning. PLoS One (2010) 1.03
Reinstatement of long-term memory following erasure of its behavioral and synaptic expression in Aplysia. Elife (2014) 1.03
New tricks for an old slug: the critical role of postsynaptic mechanisms in learning and memory in Aplysia. Prog Brain Res (2008) 1.03
BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state. Mol Pain (2013) 1.03
Dynamic learning and memory, synaptic plasticity and neurogenesis: an update. Front Behav Neurosci (2014) 1.02
Protein kinase M maintains long-term sensitization and long-term facilitation in aplysia. J Neurosci (2011) 1.02
Memory maintenance by PKMζ--an evolutionary perspective. Mol Brain (2012) 1.01
Pin1 and PKMzeta sequentially control dendritic protein synthesis. Sci Signal (2010) 1.00
Peripheral delivery of a ROCK inhibitor improves learning and working memory. Behav Neurosci (2009) 1.00
Erasing sensorimotor memories via PKMzeta inhibition. PLoS One (2010) 1.00
A high through-put reverse genetic screen identifies two genes involved in remote memory in mice. PLoS One (2008) 0.99
Predicting not to predict too much: how the cellular machinery of memory anticipates the uncertain future. Philos Trans R Soc Lond B Biol Sci (2009) 0.99
Psychological and neural mechanisms of experimental extinction: a selective review. Neurobiol Learn Mem (2013) 0.99
Cellular, molecular, and epigenetic mechanisms in non-associative conditioning: implications for pain and memory. Neurobiol Learn Mem (2013) 0.98
Contribution of PKMζ-dependent and independent amplification to components of experimental neuropathic pain. Pain (2012) 0.98
Enhancement of extinction learning attenuates ethanol-seeking behavior and alters plasticity in the prefrontal cortex. J Neurosci (2014) 0.96
KIBRA (KIdney/BRAin protein) regulates learning and memory and stabilizes Protein kinase Mζ. J Neurochem (2013) 0.95
Signalling pathways underlying structural plasticity of dendritic spines. Br J Pharmacol (2011) 0.95
Visual recognition memory, manifested as long-term habituation, requires synaptic plasticity in V1. Nat Neurosci (2015) 0.94
Nerve growth factor enhances the excitability of rat sensory neurons through activation of the atypical protein kinase C isoform, PKMζ. J Neurophysiol (2011) 0.94
How the mechanisms of long-term synaptic potentiation and depression serve experience-dependent plasticity in primary visual cortex. Philos Trans R Soc Lond B Biol Sci (2013) 0.94
Specific involvement of atypical PKCζ/PKMζ in spinal persistent nociceptive processing following peripheral inflammation in rat. Mol Pain (2011) 0.93
mTOR regulates brain morphogenesis by mediating GSK3 signaling. Development (2014) 0.93
Erasing injury-related cortical synaptic potentiation as a new treatment for chronic pain. J Mol Med (Berl) (2011) 0.93
ZIPping to pain relief: the role (or not) of PKMζ in chronic pain. Mol Pain (2013) 0.93
Improved spatial learning in aged rats by genetic activation of protein kinase C in small groups of hippocampal neurons. Hippocampus (2009) 0.93
The substrate for long-lasting memory: if not protein synthesis, then what? Neurobiol Learn Mem (2007) 0.91
The CRISP theory of hippocampal function in episodic memory. Front Neural Circuits (2013) 0.91
The right time to learn: mechanisms and optimization of spaced learning. Nat Rev Neurosci (2016) 0.91
Brain mechanisms of flavor learning. Front Syst Neurosci (2011) 0.90
PKMζ is necessary and sufficient for synaptic clustering of PSD-95. Hippocampus (2011) 0.90
PKM and the maintenance of memory. F1000 Biol Rep (2013) 0.89
Does PKM(zeta) maintain memory? Brain Res Bull (2013) 0.89
Mechanism for long-term memory formation when synaptic strengthening is impaired. Proc Natl Acad Sci U S A (2011) 0.89
Protein degradation and protein synthesis in long-term memory formation. Front Mol Neurosci (2014) 0.88
What does it take to demonstrate memory erasure? Theoretical comment on Norrholm et al. (2008). Behav Neurosci (2008) 0.88
Storing maternal memories: hypothesizing an interaction of experience and estrogen on sensory cortical plasticity to learn infant cues. Front Neuroendocrinol (2013) 0.87
A critical role for protein degradation in the nucleus accumbens core in cocaine reward memory. Neuropsychopharmacology (2012) 0.87
Cognitive flexibility is associated with KIBRA variant and modulated by recent tobacco use. Neuropsychopharmacology (2009) 0.87
Involvement of the insular cortex in regulating glucocorticoid effects on memory consolidation of inhibitory avoidance training. Front Behav Neurosci (2012) 0.87
PKA and PKC are required for long-term but not short-term in vivo operant memory in Aplysia. Learn Mem (2010) 0.87
Is epilepsy a preventable disorder? New evidence from animal models. Neuroscientist (2010) 0.86
Establishing aversive, but not safe, taste memories requires lateralized pontine-cortical connections. Behav Brain Res (2008) 0.86
Acute physiological stress promotes clustering of synaptic markers and alters spine morphology in the hippocampus. PLoS One (2013) 0.86
Persistent long-term synaptic plasticity requires activation of a new signaling pathway by additional stimuli. J Neurosci (2011) 0.86
Fos and Jun potentiate individual release sites and mobilize the reserve synaptic vesicle pool at the Drosophila larval motor synapse. Proc Natl Acad Sci U S A (2009) 0.85
Molecular determinants of the spacing effect. Neural Plast (2012) 0.85
Interplay of amygdala and cingulate plasticity in emotional fear. Neural Plast (2011) 0.85
Neural Protein Synthesis during Aging: Effects on Plasticity and Memory. Front Aging Neurosci (2010) 0.84
Intra-amygdala infusion of the protein kinase Mzeta inhibitor ZIP disrupts foreground context fear memory. Neurobiol Learn Mem (2012) 0.84
Zeta Inhibitory Peptide Disrupts Electrostatic Interactions That Maintain Atypical Protein Kinase C in Its Active Conformation on the Scaffold p62. J Biol Chem (2015) 0.83
Dietary cholesterol alters memory and synaptic structural plasticity in young rat brain. Neurol Sci (2012) 0.83
Overexpression of PKMζ alters morphology and function of dendritic spines in cultured cortical neurons. Cereb Cortex (2011) 0.83
Rescue of long-term memory after reconsolidation blockade. Nat Commun (2015) 0.82
The protein kinase Mζ network as a bistable switch to store neuronal memory. BMC Syst Biol (2010) 0.82
NMDA receptor glycine modulatory site in the ventral tegmental area regulates the acquisition, retrieval, and reconsolidation of cocaine reward memory. Psychopharmacology (Berl) (2011) 0.82
Cellular and subcellular localization of PKMζ. Philos Trans R Soc Lond B Biol Sci (2013) 0.82
Post-learning molecular reactivation underlies taste memory consolidation. Front Syst Neurosci (2011) 0.82
Overexpression of Protein Kinase Mζ in the Prelimbic Cortex Enhances the Formation of Long-Term Fear Memory. Neuropsychopharmacology (2015) 0.81
Enhance, delete, incept: manipulating hippocampus-dependent memories. Brain Res Bull (2014) 0.81
Late Protein Synthesis-Dependent Phases in CTA Long-Term Memory: BDNF Requirement. Front Behav Neurosci (2011) 0.81
Inhibition of protein kinase Mζ disrupts the stable spatial discharge of hippocampal place cells in a familiar environment. J Neurosci (2012) 0.81
Long-lasting memory from evanescent networks. Eur J Pharmacol (2008) 0.81
Visual recognition memory: a view from V1. Curr Opin Neurobiol (2015) 0.81
Storage of spatial information by the maintenance mechanism of LTP. Science (2006) 6.71
Stability of retrieved memory: inverse correlation with trace dominance. Science (2003) 3.27
Memory reconsolidation: sensitivity of spatial memory to inhibition of protein synthesis in dorsal hippocampus during encoding and retrieval. Neuron (2006) 2.75
Protein kinase M zeta synthesis from a brain mRNA encoding an independent protein kinase C zeta catalytic domain. Implications for the molecular mechanism of memory. J Biol Chem (2003) 2.28
PKMzeta maintains memories by regulating GluR2-dependent AMPA receptor trafficking. Nat Neurosci (2010) 2.28
PKM zeta maintains late long-term potentiation by N-ethylmaleimide-sensitive factor/GluR2-dependent trafficking of postsynaptic AMPA receptors. J Neurosci (2008) 2.26
Memory enhancement and formation by atypical PKM activity in Drosophila melanogaster. Nat Neurosci (2002) 2.00
Persistent phosphorylation by protein kinase Mzeta maintains late-phase long-term potentiation. J Neurosci (2005) 1.86
Enhanced intersubject correlations during movie viewing correlate with successful episodic encoding. Neuron (2008) 1.86
Enhancement of consolidated long-term memory by overexpression of protein kinase Mzeta in the neocortex. Science (2011) 1.84
Following the crowd: brain substrates of long-term memory conformity. Science (2011) 1.74
Regulation of protein kinase Mzeta synthesis by multiple kinases in long-term potentiation. J Neurosci (2007) 1.55
Synaptic tagging and cross-tagging: the role of protein kinase Mzeta in maintaining long-term potentiation but not long-term depression. J Neurosci (2005) 1.53
Reconsolidation of fresh, remote, and extinguished fear memory in Medaka: old fears don't die. Eur J Neurosci (2004) 1.48
The privileged brain representation of first olfactory associations. Curr Biol (2009) 1.47
Inhibition of PKMzeta in nucleus accumbens core abolishes long-term drug reward memory. J Neurosci (2011) 1.40
Dendritic transport and localization of protein kinase Mzeta mRNA: implications for molecular memory consolidation. J Biol Chem (2004) 1.34
The amygdalar circuit that acquires taste aversion memory differs from the circuit that extinguishes it. Eur J Neurosci (2003) 1.25
Boundary conditions for the maintenance of memory by PKMzeta in neocortex. Learn Mem (2009) 1.22
Matching biochemical and functional efficacies confirm ZIP as a potent competitive inhibitor of PKMζ in neurons. Neuropharmacology (2012) 1.20
The posterior parietal cortex in recognition memory: a neuropsychological study. Neuropsychologia (2007) 1.16
Amygdalar circuits required for either consolidation or extinction of taste aversion memory are not required for reconsolidation. Eur J Neurosci (2004) 1.13
Protein synthesis-dependent LTP in isolated dendrites of CA1 pyramidal cells. Hippocampus (2005) 1.12
Fear thou not: activity of frontal and temporal circuits in moments of real-life courage. Neuron (2010) 1.09
They saw a movie: long-term memory for an extended audiovisual narrative. Learn Mem (2007) 1.09
Conflicting processes in the extinction of conditioned taste aversion: behavioral and molecular aspects of latency, apparent stagnation, and spontaneous recovery. Learn Mem (2003) 1.05
Constructing realistic engrams: poststimulus activity of hippocampus and dorsal striatum predicts subsequent episodic memory. J Neurosci (2011) 1.03
Uncovering camouflage: amygdala activation predicts long-term memory of induced perceptual insight. Neuron (2011) 1.02
Actin polymerization regulates the synthesis of PKMzeta in LTP. Neuropharmacology (2006) 1.01
Erasing sensorimotor memories via PKMzeta inhibition. PLoS One (2010) 1.00
Spectral evidence for the presence of tryptophan in the binding site of acetylcholinesterase. FEBS Lett (1973) 0.98
Mesmerizing memories: brain substrates of episodic memory suppression in posthypnotic amnesia. Neuron (2008) 0.97
Long-term potentiation decay and memory loss are mediated by AMPAR endocytosis. J Clin Invest (2014) 0.96
Blockade of cochlear NMDA receptors prevents long-term tinnitus during a brief consolidation window after acoustic trauma. Neural Plast (2007) 0.94
Neural signature of taste familiarity in the gustatory cortex of the freely behaving rat. J Neurophysiol (2004) 0.93
Role of cortical cannabinoid CB1 receptor in conditioned taste aversion memory. Eur J Neurosci (2007) 0.90
PKMζ is necessary and sufficient for synaptic clustering of PSD-95. Hippocampus (2011) 0.90
Magnesium blocks the loss of protein kinase C, leads to a transient translocation of PKC(alpha) and PKC(epsilon), and improves recovery after anoxia in rat hippocampal slices. Brain Res Mol Brain Res (2005) 0.89
Hippocampal immediate poststimulus activity in the encoding of consecutive naturalistic episodes. J Exp Psychol Gen (2013) 0.89
Signatures of Memory: Brain Coactivations during Retrieval Distinguish Correct from Incorrect Recollection. Front Behav Neurosci (2010) 0.87
Working memory across nostrils. Behav Neurosci (2008) 0.87
Subjective vs. documented reality: a case study of long-term real-life autobiographical memory. Learn Mem (2009) 0.86
Differential pattern of cAMP response element-binding protein activation in the rat brain after conditioned aversion as a function of the associative process engaged: taste versus context association. J Neurosci (2003) 0.84
Protein kinase Mzeta is essential for the induction and maintenance of dopamine-induced long-term potentiation in apical CA1 dendrites. Learn Mem (2010) 0.83
Overexpression of PKMζ alters morphology and function of dendritic spines in cultured cortical neurons. Cereb Cortex (2011) 0.83
Cellular and subcellular localization of PKMζ. Philos Trans R Soc Lond B Biol Sci (2013) 0.82
Anxiety-like state associates with taste to produce conditioned taste aversion. Biol Psychiatry (2004) 0.82
Taste-dependent sociophobia: when food and company do not mix. Behav Brain Res (2008) 0.81
The episodic engram transformed: Time reduces retrieval-related brain activity but correlates it with memory accuracy. Learn Mem (2012) 0.80
The Naïve and the Distrustful: state dependency of hippocampal computations in manipulative memory distortion. Hippocampus (2014) 0.76
Neurobiology: Fear thou not. Nature (2003) 0.76
Yadin Dudai. Curr Biol (2013) 0.76
MAPK cascades in the brain: lessons from learning. Methods Mol Biol (2004) 0.75
Neurobiology: caught in the act. Nature (2003) 0.75
Cognitive Architectures. Neuron (2015) 0.75