Detection of near-atmospheric concentrations of CO2 by an olfactory subsystem in the mouse.

PubWeight™: 2.18‹?› | Rank: Top 2%

🔗 View Article (PMID 17702944)

Published in Science on August 17, 2007

Authors

Ji Hu1, Chun Zhong, Cheng Ding, Qiuyi Chi, Andreas Walz, Peter Mombaerts, Hiroaki Matsunami, Minmin Luo

Author Affiliations

1: National Institute of Biological Sciences, Beijing, 102206, China.

Articles citing this

Guard cell signal transduction network: advances in understanding abscisic acid, CO2, and Ca2+ signaling. Annu Rev Plant Biol (2010) 3.87

The taste of carbonation. Science (2009) 2.67

Central respiratory chemoreception. J Comp Neurol (2010) 2.06

Acute carbon dioxide avoidance in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2008) 1.97

Evolution of the gene lineage encoding the carbon dioxide receptor in insects. J Insect Sci (2009) 1.51

A Family of non-GPCR Chemosensors Defines an Alternative Logic for Mammalian Olfaction. Cell (2016) 1.49

An olfactory subsystem that detects carbon disulfide and mediates food-related social learning. Curr Biol (2010) 1.44

Receptor-type guanylate cyclase is required for carbon dioxide sensation by Caenorhabditis elegans. Proc Natl Acad Sci U S A (2010) 1.42

Guanylyl cyclase-D in the olfactory CO2 neurons is activated by bicarbonate. Proc Natl Acad Sci U S A (2009) 1.40

High CO2 levels impair alveolar epithelial function independently of pH. PLoS One (2007) 1.33

Urinary volatile compounds as biomarkers for lung cancer: a proof of principle study using odor signatures in mouse models of lung cancer. PLoS One (2010) 1.31

Temperature, oxygen, and salt-sensing neurons in C. elegans are carbon dioxide sensors that control avoidance behavior. Neuron (2011) 1.30

Central functions of bicarbonate in S-type anion channel activation and OST1 protein kinase in CO2 signal transduction in guard cell. EMBO J (2011) 1.25

Elevated CO(2) levels cause mitochondrial dysfunction and impair cell proliferation. J Biol Chem (2011) 1.24

Olfactory receptor multigene family in vertebrates: from the viewpoint of evolutionary genomics. Curr Genomics (2012) 1.20

Phosphodiesterase 1C is dispensable for rapid response termination of olfactory sensory neurons. Nat Neurosci (2009) 1.19

Physiological carbon dioxide, bicarbonate, and pH sensing. Pflugers Arch (2010) 1.18

Mammalian pheromones. Annu Rev Physiol (2013) 1.16

Neural Control of Breathing and CO2 Homeostasis. Neuron (2015) 1.11

The neuronal correlates of intranasal trigeminal function-an ALE meta-analysis of human functional brain imaging data. Brain Res Rev (2009) 1.11

Retrotrapezoid nucleus, respiratory chemosensitivity and breathing automaticity. Respir Physiol Neurobiol (2009) 1.10

Carbon dioxide-sensing in organisms and its implications for human disease. Cell Mol Life Sci (2013) 1.10

Elevated CO2 suppresses specific Drosophila innate immune responses and resistance to bacterial infection. Proc Natl Acad Sci U S A (2009) 1.09

Stimulation of guanylyl cyclase-D by bicarbonate. Biochemistry (2009) 1.09

Regulation of breathing and autonomic outflows by chemoreceptors. Compr Physiol (2014) 1.09

Olfactory receptors: G protein-coupled receptors and beyond. J Neurochem (2009) 1.08

Sensing, physiological effects and molecular response to elevated CO2 levels in eukaryotes. J Cell Mol Med (2009) 1.06

Receptor guanylyl cyclases in mammalian olfactory function. Mol Cell Biochem (2009) 1.04

Olfactory mechanisms of stereotyped behavior: on the scent of specialized circuits. Curr Opin Neurobiol (2010) 1.03

Glutamatergic signaling from the parabrachial nucleus plays a critical role in hypercapnic arousal. J Neurosci (2013) 1.02

Aversion and attraction through olfaction. Curr Biol (2015) 1.01

Different profiles of main and accessory olfactory bulb mitral/tufted cell projections revealed in mice using an anterograde tracer and a whole-mount, flattened cortex preparation. Chem Senses (2010) 1.01

A single gene target of an ETS-family transcription factor determines neuronal CO2-chemosensitivity. PLoS One (2012) 1.00

Differentiation of carbon dioxide-sensing neurons in Caenorhabditis elegans requires the ETS-5 transcription factor. Genetics (2011) 1.00

Mammalian olfactory receptors. Front Cell Neurosci (2009) 0.99

Better smelling through genetics: mammalian odor perception. Curr Opin Neurobiol (2008) 0.99

Out of thin air: sensory detection of oxygen and carbon dioxide. Neuron (2011) 0.98

Redefining the components of central CO2 chemosensitivity--towards a better understanding of mechanism. J Physiol (2011) 0.98

Grueneberg ganglion olfactory subsystem employs a cGMP signaling pathway. J Comp Neurol (2009) 0.96

Degeneration of the olfactory guanylyl cyclase D gene during primate evolution. PLoS One (2007) 0.96

V-ATPase expression in the mouse olfactory epithelium. Am J Physiol Cell Physiol (2008) 0.95

Sedation or inhalant anesthesia before euthanasia with CO2 does not reduce behavioral or physiologic signs of pain and stress in mice. J Am Assoc Lab Anim Sci (2012) 0.93

Expression of cGMP signaling elements in the Grueneberg ganglion. Histochem Cell Biol (2008) 0.93

Heterogeneous sensory innervation and extensive intrabulbar connections of olfactory necklace glomeruli. PLoS One (2009) 0.92

Distinct ONE-GC transduction modes and motifs of the odorants: Uroguanylin and CO(2). Biochem Biophys Res Commun (2009) 0.91

A chemoreceptor that detects molecular carbon dioxide. J Biol Chem (2013) 0.91

Stimulation of mammalian G-protein-responsive adenylyl cyclases by carbon dioxide. J Biol Chem (2008) 0.88

The receptor guanylyl cyclase type D (GC-D) ligand uroguanylin promotes the acquisition of food preferences in mice. Chem Senses (2013) 0.88

The bed nucleus of the stria terminalis is critical for anxiety-related behavior evoked by CO2 and acidosis. J Neurosci (2014) 0.87

Physiological sensing of carbon dioxide/bicarbonate/pH via cyclic nucleotide signaling. Sensors (Basel) (2011) 0.87

Receptor guanylyl cyclase-G is a novel thermosensory protein activated by cool temperatures. EMBO J (2014) 0.87

Trpc2-expressing sensory neurons in the mouse main olfactory epithelium of type B express the soluble guanylate cyclase Gucy1b2. Mol Cell Neurosci (2015) 0.86

Stimulus selection for intranasal sensory isolation: eugenol is an irritant. Chem Senses (2012) 0.86

EGL-13/SoxD specifies distinct O2 and CO2 sensory neuron fates in Caenorhabditis elegans. PLoS Genet (2013) 0.84

Distinct Cellular Locations of Carbonic Anhydrases Mediate Carbon Dioxide Control of Stomatal Movements. Plant Physiol (2015) 0.84

Ca(2+)-sensors and ROS-GC: interlocked sensory transduction elements: a review. Front Mol Neurosci (2012) 0.84

Ca(2+) sensor GCAP1: A constitutive element of the ONE-GC-modulated odorant signal transduction pathway. Biochemistry (2010) 0.83

Evaluation of carbon dioxide dissipation within a euthanasia chamber. J Am Assoc Lab Anim Sci (2014) 0.83

A Good Death? Report of the Second Newcastle Meeting on Laboratory Animal Euthanasia. Animals (Basel) (2016) 0.82

Electrophysiological characterization of Grueneberg ganglion olfactory neurons: spontaneous firing, sodium conductance, and hyperpolarization-activated currents. J Neurophysiol (2012) 0.82

The neurobiology of sensing respiratory gases for the control of animal behavior. Front Biol (Beijing) (2012) 0.82

Natriuretic peptides block synaptic transmission by activating phosphodiesterase 2A and reducing presynaptic PKA activity. Proc Natl Acad Sci U S A (2012) 0.82

Environmental CO2 inhibits Caenorhabditis elegans egg-laying by modulating olfactory neurons and evokes widespread changes in neural activity. Proc Natl Acad Sci U S A (2015) 0.81

Afferent activity to necklace glomeruli is dependent on external stimuli. BMC Res Notes (2009) 0.81

CD36 is involved in oleic acid detection by the murine olfactory system. Front Cell Neurosci (2015) 0.81

Neural mechanisms of alarm pheromone signaling. Mol Cells (2013) 0.81

Loss of the V-ATPase B1 subunit isoform expressed in non-neuronal cells of the mouse olfactory epithelium impairs olfactory function. PLoS One (2012) 0.80

Fos-Tau-LacZ mice reveal sex differences in brainstem c-fos activation in response to mild carbon dioxide exposure. Brain Res (2009) 0.80

The Evolving Neural and Genetic Architecture of Vertebrate Olfaction. Curr Biol (2016) 0.79

Molecular and neuronal homology between the olfactory systems of zebrafish and mouse. Sci Rep (2015) 0.79

Carbon dioxide and oxygen levels in disposable individually ventilated cages after removal from mechanical ventilation. J Am Assoc Lab Anim Sci (2012) 0.79

Stability and flexibility of the message carried by semiochemical stimuli, as revealed by devaluation of carbon disulfide followed by social transmission of food preference. Behav Neurosci (2014) 0.78

Possible functional role of olfactory subsystems in monitoring inhalation and exhalation. Front Neuroanat (2014) 0.78

Automated analyses of innate olfactory behaviors in rodents. PLoS One (2014) 0.77

Interaction between δ opioid receptors and benzodiazepines in CO₂-induced respiratory responses in mice. Brain Res (2011) 0.77

Integrative Signaling Networks of Membrane Guanylate Cyclases: Biochemistry and Physiology. Front Mol Neurosci (2016) 0.76

Defying the stereotype: non-canonical roles of the Peptide hormones guanylin and uroguanylin. Front Endocrinol (Lausanne) (2011) 0.76

Imaging calcium responses in GFP-tagged neurons of hypothalamic mouse brain slices. J Vis Exp (2012) 0.76

CD36 is expressed in a defined subpopulation of neurons in the olfactory epithelium. Sci Rep (2016) 0.75

Olfactory carbon dioxide detection by insects and other animals. Mol Cells (2013) 0.75

Articles by these authors

Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell (2011) 9.16

RTP family members induce functional expression of mammalian odorant receptors. Cell (2004) 4.09

Cell type–specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function. Nat Methods (2011) 4.02

Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia. Genome Res (2003) 3.50

In vivo imaging of neuronal activity by targeted expression of a genetically encoded probe in the mouse. Neuron (2004) 3.40

Genetic variation in a human odorant receptor alters odour perception. Nature (2007) 3.30

Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor. Proc Natl Acad Sci U S A (2006) 3.24

Odorant receptor expression defines functional units in the mouse olfactory system. J Neurosci (2002) 3.18

Odor coding by a Mammalian receptor repertoire. Sci Signal (2009) 2.84

Minigenes impart odorant receptor-specific axon guidance in the olfactory bulb. Neuron (2002) 2.82

Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision. Nature (2012) 2.73

Axon guidance of mouse olfactory sensory neurons by odorant receptors and the beta2 adrenergic receptor. Cell (2004) 2.41

Deficient pheromone responses in mice lacking a cluster of vomeronasal receptor genes. Nature (2002) 2.41

Local and cis effects of the H element on expression of odorant receptor genes in mouse. Cell (2007) 2.30

A contextual model for axonal sorting into glomeruli in the mouse olfactory system. Cell (2004) 2.24

Multiple new and isolated families within the mouse superfamily of V1r vomeronasal receptors. Nat Neurosci (2002) 2.20

Habenula "cholinergic" neurons co-release glutamate and acetylcholine and activate postsynaptic neurons via distinct transmission modes. Neuron (2011) 2.14

Odorant receptor gene choice is reset by nuclear transfer from mouse olfactory sensory neurons. Nature (2004) 2.09

Precise circuitry links bilaterally symmetric olfactory maps. Neuron (2008) 1.84

Odorant and vomeronasal receptor genes in two mouse genome assemblies. Genomics (2004) 1.82

Synergism of accessory factors in functional expression of mammalian odorant receptors. J Biol Chem (2007) 1.80

In vivo identification of regulators of cell invasion across basement membranes. Sci Signal (2010) 1.77

Postnatal refinement of peripheral olfactory projections. Science (2004) 1.73

Dual functions of mammalian olfactory sensory neurons as odor detectors and mechanical sensors. Nat Neurosci (2007) 1.71

Specificity of glomerular targeting by olfactory sensory axons. J Neurosci (2002) 1.67

Mapping of class I and class II odorant receptors to glomerular domains by two distinct types of olfactory sensory neurons in the mouse. Neuron (2009) 1.66

TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation. Neuron (2013) 1.64

The candidate sour taste receptor, PKD2L1, is expressed by type III taste cells in the mouse. Chem Senses (2007) 1.63

Genetic variation in the odorant receptor OR2J3 is associated with the ability to detect the "grassy" smelling odor, cis-3-hexen-1-ol. Chem Senses (2012) 1.63

Structural requirements for the activation of vomeronasal sensory neurons by MHC peptides. Nat Neurosci (2009) 1.60

Genetic disruptions of O/E2 and O/E3 genes reveal involvement in olfactory receptor neuron projection. Development (2004) 1.59

The LIM-homeodomain protein Lhx2 is required for complete development of mouse olfactory sensory neurons. Proc Natl Acad Sci U S A (2004) 1.58

Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond. Cell Cycle (2011) 1.55

Evaluating cell-surface expression and measuring activation of mammalian odorant receptors in heterologous cells. Nat Protoc (2008) 1.54

Odorant responses of olfactory sensory neurons expressing the odorant receptor MOR23: a patch clamp analysis in gene-targeted mice. Proc Natl Acad Sci U S A (2006) 1.52

Odor information processing by the olfactory bulb analyzed in gene-targeted mice. Neuron (2010) 1.51

Protocols for two- and three-color fluorescent RNA in situ hybridization of the main and accessory olfactory epithelia in mouse. J Neurocytol (2005) 1.50

Acute and long-term suppression of feeding behavior by POMC neurons in the brainstem and hypothalamus, respectively. J Neurosci (2013) 1.48

Regulation of the probability of mouse odorant receptor gene choice. Cell (2011) 1.44

Secreted frizzled-related protein 3 regulates activity-dependent adult hippocampal neurogenesis. Cell Stem Cell (2013) 1.42

The protocadherin-alpha family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse. Mol Cell Neurosci (2008) 1.42

G protein G(alpha)o is essential for vomeronasal function and aggressive behavior in mice. Proc Natl Acad Sci U S A (2011) 1.41

Combinatorial coexpression of neural and immune multigene families in mouse vomeronasal sensory neurons. Curr Biol (2003) 1.40

Guanylyl cyclase-D in the olfactory CO2 neurons is activated by bicarbonate. Proc Natl Acad Sci U S A (2009) 1.40

Odorant receptors instruct functional circuitry in the mouse olfactory bulb. Nature (2002) 1.37

Optogenetic activation of basal forebrain cholinergic neurons modulates neuronal excitability and sensory responses in the main olfactory bulb. J Neurosci (2012) 1.32

Functional analysis of a mammalian odorant receptor subfamily. J Neurochem (2006) 1.30

Sour taste responses in mice lacking PKD channels. PLoS One (2011) 1.29

SR1, a mouse odorant receptor with an unusually broad response profile. J Neurosci (2009) 1.28

Expression of nonclassical class I major histocompatibility genes defines a tripartite organization of the mouse vomeronasal system. J Neurosci (2008) 1.24

Novel human vomeronasal receptor-like genes reveal species-specific families. Curr Biol (2002) 1.23

Neuronal expression of the Ccm2 gene in a new mouse model of cerebral cavernous malformations. Mamm Genome (2006) 1.23

Mice cloned from skin cells. Proc Natl Acad Sci U S A (2007) 1.23

The promoter of the mouse odorant receptor gene M71. Mol Cell Neurosci (2005) 1.21

Aberrant sensory innervation of the olfactory bulb in neuropilin-2 mutant mice. J Neurosci (2002) 1.21

Basement membrane sliding and targeted adhesion remodels tissue boundaries during uterine-vulval attachment in Caenorhabditis elegans. Nat Cell Biol (2011) 1.20

Role for the membrane receptor guanylyl cyclase-C in attention deficiency and hyperactive behavior. Science (2011) 1.19

Off-response property of an acid-activated cation channel complex PKD1L3-PKD2L1. EMBO Rep (2008) 1.19

Activation state of the M3 muscarinic acetylcholine receptor modulates mammalian odorant receptor signaling. Sci Signal (2011) 1.18

Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci (2007) 1.15

Receptors for bitter and sweet taste. Curr Opin Neurobiol (2002) 1.15

A divergent pattern of sensory axonal projections is rendered convergent by second-order neurons in the accessory olfactory bulb. Neuron (2002) 1.15

Parvalbumin interneurons mediate neuronal circuitry-neurogenesis coupling in the adult hippocampus. Nat Neurosci (2013) 1.13

Massive and destructive T cell response to homeostatic cue in CD24-deficient lymphopenic hosts. J Exp Med (2006) 1.11

The netrin receptor DCC focuses invadopodia-driven basement membrane transmigration in vivo. J Cell Biol (2013) 1.11

Promoter architecture of mouse olfactory receptor genes. Genome Res (2011) 1.06

The Grueneberg ganglion of the mouse projects axons to glomeruli in the olfactory bulb. Eur J Neurosci (2005) 1.06

Functional evolution of mammalian odorant receptors. PLoS Genet (2012) 1.05

Temporal patterns of odorant receptor gene expression in adult and aged mice. Mol Cell Neurosci (2013) 1.03

Calreticulin chaperones regulate functional expression of vomeronasal type 2 pheromone receptors. Proc Natl Acad Sci U S A (2011) 1.03

A family of nonclassical class I MHC genes contributes to ultrasensitive chemodetection by mouse vomeronasal sensory neurons. J Neurosci (2014) 1.02

Diverse patterns of odor representation by neurons in the anterior piriform cortex of awake mice. J Neurosci (2010) 1.02

Interaction between PKD1L3 and PKD2L1 through their transmembrane domains is required for localization of PKD2L1 at taste pores in taste cells of circumvallate and foliate papillae. FASEB J (2010) 1.01

Axonal wiring of guanylate cyclase-D-expressing olfactory neurons is dependent on neuropilin 2 and semaphorin 3F. Development (2007) 1.00

Homeodomain binding motifs modulate the probability of odorant receptor gene choice in transgenic mice. Mol Cell Neurosci (2010) 1.00

Disrupted compartmental organization of axons and dendrites within olfactory glomeruli of mice deficient in the olfactory cell adhesion molecule, OCAM. Mol Cell Neurosci (2006) 0.99

Crucial role of copper in detection of metal-coordinating odorants. Proc Natl Acad Sci U S A (2012) 0.96

Optimizing cholinergic tone through lynx modulators of nicotinic receptors: implications for plasticity and nicotine addiction. Physiology (Bethesda) (2012) 0.96

Coordinated coexpression of two vomeronasal receptor V2R genes per neuron in the mouse. Mol Cell Neurosci (2010) 0.95

Development and topography of the lateral olfactory tract in the mouse: imaging by genetically encoded and injected fluorescent markers. J Neurobiol (2006) 0.94

Cortical-like functional organization of the pheromone-processing circuits in the medial amygdala. J Neurophysiol (2007) 0.93

General olfactory sensitivity database (GOSdb): candidate genes and their genomic variations. Hum Mutat (2012) 0.93

Interleukin-10 gene polymorphisms and chronic/aggressive periodontitis susceptibility: a meta-analysis based on 14 case-control studies. Cytokine (2012) 0.90

ADF/cofilin promotes invadopodial membrane recycling during cell invasion in vivo. J Cell Biol (2014) 0.90

Odorant receptor gene choice and axonal wiring in mice with deletion mutations in the odorant receptor gene SR1. Mol Cell Neurosci (2013) 0.90

Adsorption, immobilization, and activity of beta-glucosidase on different soil colloids. J Colloid Interface Sci (2010) 0.89

Receptors, circuits, and behaviors: new directions in chemical senses. J Neurosci (2008) 0.89

Dynamic functional evolution of an odorant receptor for sex-steroid-derived odors in primates. Proc Natl Acad Sci U S A (2009) 0.89

Genetic variation of an odorant receptor OR7D4 and sensory perception of cooked meat containing androstenone. PLoS One (2012) 0.88

Amelioration of renal ischemia-reperfusion injury with a novel protective cocktail. J Urol (2011) 0.88

Non-equivalence of cloned and clonal mice. Curr Biol (2005) 0.87

Nuclear transfer-mediated rescue of the nuclear genome of nonviable mouse cells frozen without cryoprotectant. Biol Reprod (2008) 0.86