Published in BMC Med Genet on August 16, 2007
The metabolic syndrome. Endocr Rev (2008) 5.33
Peroxisome proliferator-activated receptors, metabolic syndrome and cardiovascular disease. Future Cardiol (2010) 1.06
PPAR-α as a key nutritional and environmental sensor for metabolic adaptation. Adv Nutr (2013) 1.04
Genetic basis of inter-individual variability in the effects of exercise on the alleviation of lifestyle-related diseases. J Physiol (2009) 1.02
Interleukin-15 and interleukin-15R alpha SNPs and associations with muscle, bone, and predictors of the metabolic syndrome. Cytokine (2008) 0.98
INSIG2 gene polymorphism is associated with increased subcutaneous fat in women and poor response to resistance training in men. BMC Med Genet (2008) 0.94
AKT1 polymorphisms are associated with risk for metabolic syndrome. Hum Genet (2011) 0.92
CNTF 1357 G -> A polymorphism and the muscle strength response to resistance training. J Appl Physiol (1985) (2009) 0.87
Highlights from the functional single nucleotide polymorphisms associated with human muscle size and strength or FAMuSS study. Biomed Res Int (2013) 0.81
Leptin and leptin receptor genetic variants associate with habitual physical activity and the arm body composition response to resistance training. Gene (2012) 0.80
Genetic variation in the peroxisome proliferator-activated receptor (PPAR) and peroxisome proliferator-activated receptor gamma co-activator 1 (PGC1) gene families and type 2 diabetes. Ann Hum Genet (2014) 0.80
Differences in transcriptional activation by the two allelic (L162V Polymorphic) variants of PPARα after Omega-3 fatty acids treatment. PPAR Res (2009) 0.79
Omega-3 fatty acids regulate gene expression levels differently in subjects carrying the PPARalpha L162V polymorphism. Genes Nutr (2009) 0.78
Role of peroxisome proliferator-activated receptors gene polymorphisms in type 2 diabetes and metabolic syndrome. World J Diabetes (2015) 0.77
Screening of Peroxisome Proliferator-Activated Receptors (PPARs) α, γ and α Gene Polymorphisms for Obesity and Metabolic Syndrome Association in the Multi-Ethnic Malaysian Population. Ethn Dis (2015) 0.75
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci U S A (1997) 7.52
A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator- activated receptor alpha- deficient mice. J Clin Invest (1998) 2.42
Peroxisome proliferator-activated receptor alpha-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis. J Biol Chem (1998) 2.37
Variability in muscle size and strength gain after unilateral resistance training. Med Sci Sports Exerc (2005) 1.95
ACE ID genotype and the muscle strength and size response to unilateral resistance training. Med Sci Sports Exerc (2006) 1.86
Peroxisome proliferator-activated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular inflammation and atherosclerosis. Curr Opin Lipidol (1999) 1.62
ACTN3 genotype is associated with increases in muscle strength in response to resistance training in women. J Appl Physiol (1985) (2005) 1.57
Variation in the PPARalpha gene is associated with altered function in vitro and plasma lipid concentrations in Type II diabetic subjects. Diabetologia (2000) 1.54
Functional polymorphisms associated with human muscle size and strength. Med Sci Sports Exerc (2004) 1.49
Molecular scanning of the human PPARa gene: association of the L162v mutation with hyperapobetalipoproteinemia. J Lipid Res (2000) 1.46
Mutation screening of the PPARalpha gene in type 2 diabetes associated with coronary heart disease. Diabetes Metab (2000) 1.26
Association between the PPARA L162V polymorphism and plasma lipid levels: the Framingham Offspring Study. Arterioscler Thromb Vasc Biol (2002) 1.23
Evidence for independent genetic influences on obesity in middle age. Int J Obes Relat Metab Disord (1992) 1.19
Linkage of the metabolic syndrome to 1q23-q31 in Hispanic families: the Insulin Resistance Atherosclerosis Study Family Study. Diabetes (2004) 1.14
The human peroxisome proliferator-activated receptor alpha gene: identification and functional characterization of two natural allelic variants. Pharmacogenetics (2000) 1.10
Polyunsaturated fatty acids interact with the PPARA-L162V polymorphism to affect plasma triglyceride and apolipoprotein C-III concentrations in the Framingham Heart Study. J Nutr (2005) 1.10
Association between the PPARalpha-L162V polymorphism and components of the metabolic syndrome. J Hum Genet (2004) 1.03
Sex difference in hepatic peroxisome proliferator-activated receptor alpha expression: influence of pituitary and gonadal hormones. Endocrinology (2003) 1.01
Peroxisome proliferator-activated receptors: structures and function. Ann N Y Acad Sci (1996) 1.01
Longitudinal genetic analysis of plasma lipids. Twin Res Hum Genet (2006) 0.93
The peroxisome proliferator-activated receptor alpha L162V mutation is associated with reduced adiposity. Obes Res (2003) 0.89
The genetics of obesity: practical implications. Int J Obes Relat Metab Disord (2001) 0.89
A polymorphism, L162V, in the peroxisome proliferator-activated receptor alpha (PPARalpha) gene is associated with lower body mass index in patients with non-insulin-dependent diabetes mellitus. J Mol Med (Berl) (2001) 0.88
Resistin polymorphisms are associated with muscle, bone, and fat phenotypes in white men and women. Obesity (Silver Spring) (2007) 0.85
Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc (2007) 20.11
Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Circulation (2007) 18.32
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31
Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. Dev Cell (2008) 5.51
The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21. Endocrinology (2006) 4.81
American College of Sports Medicine position stand. Exercise and hypertension. Med Sci Sports Exerc (2004) 4.48
Mortality and morbidity in laboratory-maintained Rhesus monkeys and effects of long-term dietary restriction. J Gerontol A Biol Sci Med Sci (2003) 3.77
Genomics, intellectual disability, and autism. N Engl J Med (2012) 3.74
Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. Cell Metab (2005) 3.47
The effects of physical activity on serum C-reactive protein and inflammatory markers: a systematic review. J Am Coll Cardiol (2005) 3.43
Cardiac arrest during long-distance running races. N Engl J Med (2012) 3.34
Testing of low-risk patients presenting to the emergency department with chest pain: a scientific statement from the American Heart Association. Circulation (2010) 2.89
Exercise standards for testing and training: a scientific statement from the American Heart Association. Circulation (2013) 2.82
The role of coenzyme Q10 in statin-associated myopathy: a systematic review. J Am Coll Cardiol (2007) 2.68
An interactive power analysis tool for microarray hypothesis testing and generation. Bioinformatics (2006) 2.62
Effect of statins on skeletal muscle function. Circulation (2012) 2.54
Oxidative stress, exercise, and antioxidant supplementation. Toxicology (2003) 2.48
Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action. Am J Physiol Endocrinol Metab (2006) 2.47
Exercise intensity alters postexercise hypotension. J Hypertens (2004) 2.45
Phytosterols and vascular disease. Atherosclerosis (2005) 2.39
Sources of variability and effect of experimental approach on expression profiling data interpretation. BMC Bioinformatics (2002) 2.31
Nuclear envelope dystrophies show a transcriptional fingerprint suggesting disruption of Rb-MyoD pathways in muscle regeneration. Brain (2006) 2.22
Preclinical drug trials in the mdx mouse: assessment of reliable and sensitive outcome measures. Muscle Nerve (2009) 2.19
An assessment of statin safety by muscle experts. Am J Cardiol (2006) 2.16
Length of psychiatric hospitalization is correlated with CYP2D6 functional status in inpatients with major depressive disorder. Biomark Med (2013) 2.13
Changes in ubiquitin proteasome pathway gene expression in skeletal muscle with exercise and statins. Arterioscler Thromb Vasc Biol (2005) 2.12
Osteopontin promotes fibrosis in dystrophic mouse muscle by modulating immune cell subsets and intramuscular TGF-beta. J Clin Invest (2009) 2.10
A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. PLoS Genet (2009) 2.09
Exercise-induced cardiac troponin elevation: evidence, mechanisms, and implications. J Am Coll Cardiol (2010) 2.06
Gene profiling in spinal cord injury shows role of cell cycle in neuronal death. Ann Neurol (2003) 2.06
SLC30A8 nonsynonymous variant is associated with recovery following exercise and skeletal muscle size and strength. Diabetes (2013) 2.05
Calorie-related rapid onset of alveolar loss, regeneration, and changes in mouse lung gene expression. Am J Physiol Lung Cell Mol Physiol (2003) 2.04
Secreted proteome profiling in human RPE cell cultures derived from donors with age related macular degeneration and age matched healthy donors. J Proteome Res (2006) 2.04
Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin. Dev Cell (2004) 2.01
Interactively optimizing signal-to-noise ratios in expression profiling: project-specific algorithm selection and detection p-value weighting in Affymetrix microarrays. Bioinformatics (2004) 1.98
Variability in muscle size and strength gain after unilateral resistance training. Med Sci Sports Exerc (2005) 1.95
ACE ID genotype and the muscle strength and size response to unilateral resistance training. Med Sci Sports Exerc (2006) 1.86
Loss of emerin at the nuclear envelope disrupts the Rb1/E2F and MyoD pathways during muscle regeneration. Hum Mol Genet (2006) 1.85
Gene expression profiling in DQA1*0501+ children with untreated dermatomyositis: a novel model of pathogenesis. J Immunol (2002) 1.83
Youth football: heat stress and injury risk. Med Sci Sports Exerc (2005) 1.83
Recommendations for physical activity and recreational sports participation for young patients with genetic cardiovascular diseases. Circulation (2004) 1.82
Tissue-specific alternative splicing of TCF7L2. Hum Mol Genet (2009) 1.80
Self-report-based estimates of energy intake offer an inadequate basis for scientific conclusions. Am J Clin Nutr (2013) 1.79
The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation. Dev Cell (2006) 1.78
Comparison of U.S. and Italian experiences with sudden cardiac deaths in young competitive athletes and implications for preparticipation screening strategies. Am J Cardiol (2009) 1.78
Constitutive activation of MAPK cascade in acute quadriplegic myopathy. Ann Neurol (2004) 1.77
Effect of statins on skeletal muscle: exercise, myopathy, and muscle outcomes. Exerc Sport Sci Rev (2012) 1.76
Exercise interventions for cancer survivors: a meta-analysis of quality of life outcomes. Ann Behav Med (2011) 1.68
Tolerability of red yeast rice (2,400 mg twice daily) versus pravastatin (20 mg twice daily) in patients with previous statin intolerance. Am J Cardiol (2009) 1.68
GRB14, GPD1, and GDF8 as potential network collaborators in weight loss-induced improvements in insulin action in human skeletal muscle. Physiol Genomics (2006) 1.67
Resistance exercise for muscular strength in older adults: a meta-analysis. Ageing Res Rev (2010) 1.66
Apolipoprotein E polymorphisms and severity of cerebral palsy: a cross-sectional study in 255 children in Norway. Dev Med Child Neurol (2013) 1.66
Efficacy of exercise interventions in modulating cancer-related fatigue among adult cancer survivors: a meta-analysis. Cancer Epidemiol Biomarkers Prev (2010) 1.66
The relationship of vitamin D deficiency to statin myopathy. Atherosclerosis (2010) 1.65
Dysferlin deficiency enhances monocyte phagocytosis: a model for the inflammatory onset of limb-girdle muscular dystrophy 2B. Am J Pathol (2008) 1.65
A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. Circ Cardiovasc Genet (2011) 1.63
Serum creatine kinase levels and renal function measures in exertional muscle damage. Med Sci Sports Exerc (2006) 1.63