Published in J Neurol Sci on September 19, 2007
Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of alpha-synuclein. J Biol Chem (2008) 1.94
Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions. J Neurosci (2010) 1.46
Neuropathology of sporadic Parkinson disease before the appearance of parkinsonism: preclinical Parkinson disease. J Neural Transm (Vienna) (2010) 1.22
Protein phosphorylation in neurodegeneration: friend or foe? Front Mol Neurosci (2014) 1.15
Parkinson's disease-implicated kinases in the brain; insights into disease pathogenesis. Front Mol Neurosci (2014) 1.03
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Casein kinase 2 phosphorylates GluA1 and regulates its surface expression. Eur J Neurosci (2014) 0.86
CK2 negatively regulates Galphas signaling. Proc Natl Acad Sci U S A (2009) 0.84
The Interplay between Alpha-Synuclein Clearance and Spreading. Biomolecules (2015) 0.84
Identification of a Potent Allosteric Inhibitor of Human Protein Kinase CK2 by Bacterial Surface Display Library Screening. Pharmaceuticals (Basel) (2017) 0.79
Impact of protein kinase CK2 inhibitors on proliferation and differentiation of neural stem cells. Heliyon (2017) 0.75
Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol (2005) 5.31
Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease. Science (2002) 4.72
Anti-inflammatory mechanism of intravascular neural stem cell transplantation in haemorrhagic stroke. Brain (2007) 3.68
Repression of alpha-synuclein expression and toxicity by microRNA-7. Proc Natl Acad Sci U S A (2009) 2.61
Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective. J Biol Chem (2003) 2.42
Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells. Proc Natl Acad Sci U S A (2007) 2.19
Human neural stem cell transplantation promotes functional recovery in rats with experimental intracerebral hemorrhage. Stroke (2003) 1.97
Association of HTRA1 mutations and familial ischemic cerebral small-vessel disease. N Engl J Med (2009) 1.96
Interaction between mutant ataxin-1 and PQBP-1 affects transcription and cell death. Neuron (2002) 1.95
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death. Proc Natl Acad Sci U S A (2005) 1.91
The role of oxidative stress in Parkinson's disease. J Parkinsons Dis (2013) 1.86
Toll-like receptor signal transduction. Exp Mol Med (2007) 1.73
Mitochondrial localization of DJ-1 leads to enhanced neuroprotection. J Neurosci Res (2009) 1.68
Neural stem cell tropism to glioma: critical role of tumor hypoxia. Mol Cancer Res (2008) 1.67
Transplantation of human neural stem cells exerts neuroprotection in a rat model of Parkinson's disease. J Neurosci (2006) 1.59
Brain transplantation of immortalized human neural stem cells promotes functional recovery in mouse intracerebral hemorrhage stroke model. Stem Cells (2007) 1.57
Human neural stem cells improve sensorimotor deficits in the adult rat brain with experimental focal ischemia. Brain Res (2004) 1.55
Early distribution of intravenously injected mesenchymal stem cells in rats with acute brain trauma evaluated by (99m)Tc-HMPAO labeling. Nucl Med Biol (2011) 1.51
The prediction of rapid conversion to Alzheimer's disease in mild cognitive impairment using regional cerebral blood flow SPECT. Neuroimage (2005) 1.47
Neuroprotective effects of human mesenchymal stem cells on dopaminergic neurons through anti-inflammatory action. Glia (2009) 1.47
Development of a tumor-selective approach to treat metastatic cancer. PLoS One (2006) 1.46
Sodium selenite induces superoxide-mediated mitochondrial damage and subsequent autophagic cell death in malignant glioma cells. Cancer Res (2007) 1.45
Human neural stem cells target experimental intracranial medulloblastoma and deliver a therapeutic gene leading to tumor regression. Clin Cancer Res (2006) 1.44
Cyclooxygenase-2 inhibitor, celecoxib, inhibits the altered hippocampal neurogenesis with attenuation of spontaneous recurrent seizures following pilocarpine-induced status epilepticus. Neurobiol Dis (2006) 1.43
Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies. Sci Transl Med (2013) 1.42
Brain tumor tropism of transplanted human neural stem cells is induced by vascular endothelial growth factor. Neoplasia (2005) 1.41
Human neural stem cells over-expressing VEGF provide neuroprotection, angiogenesis and functional recovery in mouse stroke model. PLoS One (2007) 1.41
Tissue transglutaminase-induced aggregation of alpha-synuclein: Implications for Lewy body formation in Parkinson's disease and dementia with Lewy bodies. Proc Natl Acad Sci U S A (2003) 1.40
Cytokines, chemokines, and cytokine receptors in human microglia. J Neurosci Res (2002) 1.39
Human neural stem cells can migrate, differentiate, and integrate after intravenous transplantation in adult rats with transient forebrain ischemia. Neurosci Lett (2003) 1.39
Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma. Cancer Res (2007) 1.38
Targeting rat brainstem glioma using human neural stem cells and human mesenchymal stem cells. Clin Cancer Res (2009) 1.38
MicroRNAs in neurodegenerative diseases and their therapeutic potential. Pharmacol Ther (2011) 1.37
Iron labeling and pre-clinical MRI visualization of therapeutic human neural stem cells in a murine glioma model. PLoS One (2009) 1.36
Molecular interaction between parkin and PINK1 in mammalian neuronal cells. Mol Cell Neurosci (2009) 1.36
Fractalkine and fractalkine receptors in human neurons and glial cells. J Neurosci Res (2002) 1.32
Brain hydrogen sulfide is severely decreased in Alzheimer's disease. Biochem Biophys Res Commun (2002) 1.32
Urokinase plasminogen activator and urokinase plasminogen activator receptor mediate human stem cell tropism to malignant solid tumors. Stem Cells (2008) 1.30
Parkin accumulation in aggresomes due to proteasome impairment. J Biol Chem (2002) 1.30
Transplantation of human mesenchymal stem cells promotes functional improvement and increased expression of neurotrophic factors in a rat focal cerebral ischemia model. J Neurosci Res (2010) 1.30
An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies. Acta Neuropathol (2006) 1.24
Human alpha-synuclein over-expression increases intracellular reactive oxygen species levels and susceptibility to dopamine. Neurosci Lett (2002) 1.23
DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway. Hum Mol Genet (2012) 1.22
Minocycline inhibits neuronal death and glial activation induced by beta-amyloid peptide in rat hippocampus. Glia (2004) 1.21
Modulation of the purinergic P2X7 receptor attenuates lipopolysaccharide-mediated microglial activation and neuronal damage in inflamed brain. J Neurosci (2007) 1.21
Enhanced phosphatase activity attenuates α-synucleinopathy in a mouse model. J Neurosci (2011) 1.20
Intravenously transplanted human neural stem cells migrate to the injured spinal cord in adult mice in an SDF-1- and HGF-dependent manner. Neurosci Lett (2007) 1.18
Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP. Oncogene (2004) 1.18
Tubulin seeds alpha-synuclein fibril formation. J Biol Chem (2001) 1.18
IL-8 enhancement of amyloid-beta (Abeta 1-42)-induced expression and production of pro-inflammatory cytokines and COX-2 in cultured human microglia. J Neuroimmunol (2004) 1.17
Diffusion abnormalities of the uncinate fasciculus in Alzheimer's disease: diffusion tensor tract-specific analysis using a new method to measure the core of the tract. Neuroradiology (2008) 1.17
Stem cell-based cell therapy for spinal cord injury. Cell Transplant (2007) 1.15
Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease. Neurobiol Dis (2004) 1.15
Ex vivo VEGF delivery by neural stem cells enhances proliferation of glial progenitors, angiogenesis, and tissue sparing after spinal cord injury. PLoS One (2009) 1.15
Neural progenitor NT2N cell lines from teratocarcinoma for transplantation therapy in stroke. Prog Neurobiol (2008) 1.15
Multilineage potential of stable human mesenchymal stem cell line derived from fetal marrow. PLoS One (2007) 1.14
Human astrocytes express aquaporin-1 and aquaporin-4 in vitro and in vivo. Neuropathology (2007) 1.14
Transplantation of human neural stem cells transduced with Olig2 transcription factor improves locomotor recovery and enhances myelination in the white matter of rat spinal cord following contusive injury. BMC Neurosci (2009) 1.13
Human neural stem cell tropism to metastatic breast cancer. Stem Cells (2012) 1.13
Inhibition of lipopolysaccharide-induced cyclooxygenase-2, tumor necrosis factor-alpha and [Ca2+]i responses in human microglia by the peripheral benzodiazepine receptor ligand PK11195. J Neurochem (2002) 1.12
Upregulation of protease-activated receptor-1 in astrocytes in Parkinson disease: astrocyte-mediated neuroprotection through increased levels of glutathione peroxidase. J Neuropathol Exp Neurol (2006) 1.12
Mesenchymal stem cells therapy exerts neuroprotection in a progressive animal model of Parkinson's disease. J Neurochem (2008) 1.12
Hippocampal complexin proteins and cognitive dysfunction in schizophrenia. Arch Gen Psychiatry (2005) 1.11
Human neural stem cells genetically modified to overexpress brain-derived neurotrophic factor promote functional recovery and neuroprotection in a mouse stroke model. J Neurosci Res (2010) 1.11
Inhibition of thrombin-induced microglial activation and NADPH oxidase by minocycline protects dopaminergic neurons in the substantia nigra in vivo. J Neurochem (2005) 1.11
Granulocyte colony-stimulating factor stimulates neurogenesis via vascular endothelial growth factor with STAT activation. Brain Res (2006) 1.10
DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex. Neurosci Res (2010) 1.10
Bcr-Abl-independent imatinib-resistant K562 cells show aberrant protein acetylation and increased sensitivity to histone deacetylase inhibitors. J Pharmacol Exp Ther (2007) 1.10
Transient receptor potential vanilloid subtype 1 mediates cell death of mesencephalic dopaminergic neurons in vivo and in vitro. J Neurosci (2005) 1.10
Casein kinase II-mediated phosphorylation regulates alpha-synuclein/synphilin-1 interaction and inclusion body formation. J Biol Chem (2003) 1.10
Human neural stem cells over-expressing choline acetyltransferase restore cognition in rat model of cognitive dysfunction. Exp Neurol (2012) 1.09
Intravenous administration of human neural stem cells induces functional recovery in Huntington's disease rat model. Neurosci Res (2005) 1.09
Neural stem cell targeting of glioma is dependent on phosphoinositide 3-kinase signaling. Stem Cells (2008) 1.09
PEX-producing human neural stem cells inhibit tumor growth in a mouse glioma model. Clin Cancer Res (2005) 1.08
Lovastatin enhances Abeta production and senile plaque deposition in female Tg2576 mice. Neurobiol Aging (2003) 1.08
Cerebral small-vessel disease protein HTRA1 controls the amount of TGF-β1 via cleavage of proTGF-β1. Hum Mol Genet (2011) 1.08
Adenosine triphosphate induces proliferation of human neural stem cells: Role of calcium and p70 ribosomal protein S6 kinase. J Neurosci Res (2003) 1.08
Thrombin-induced microglial activation produces degeneration of nigral dopaminergic neurons in vivo. J Neurosci (2003) 1.08
Broad-spectrum effects of 4-aminopyridine to modulate amyloid beta1-42-induced cell signaling and functional responses in human microglia. J Neurosci (2006) 1.07
Magnetic resonance imaging tracking of ferumoxytol-labeled human neural stem cells: studies leading to clinical use. Stem Cells Transl Med (2013) 1.07
In vivo animal stroke models: a rationale for rodent and non-human primate models. Transl Stroke Res (2013) 1.07
Human microglial cells synthesize albumin in brain. PLoS One (2008) 1.07
Human microglia transplanted in rat focal ischemia brain induce neuroprotection and behavioral improvement. PLoS One (2010) 1.07
Neural stem cells as a novel platform for tumor-specific delivery of therapeutic antibodies. PLoS One (2009) 1.05
Molecular modeling-based evaluation of hTLR10 and identification of potential ligands in Toll-like receptor signaling. PLoS One (2010) 1.05
Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin. Cancer Res (2007) 1.05
TDP-43 dimerizes in human cells in culture. Cell Mol Neurobiol (2009) 1.04
Arsenic trioxide sensitizes human glioma cells, but not normal astrocytes, to TRAIL-induced apoptosis via CCAAT/enhancer-binding protein homologous protein-dependent DR5 up-regulation. Cancer Res (2008) 1.04
Human neural stem cells overexpressing choline acetyltransferase restore cognitive function of kainic acid-induced learning and memory deficit animals. Cell Transplant (2011) 1.04
Nogo-A and nogo receptor expression in demyelinating lesions of multiple sclerosis. J Neuropathol Exp Neurol (2005) 1.03
Vascular endothelial growth factor-stimulated cerebral microvascular endothelial cells mediate the recruitment of neural stem cells to the neurovascular niche. Brain Res (2009) 1.03
Molecular network analysis suggests aberrant CREB-mediated gene regulation in the Alzheimer disease hippocampus. Dis Markers (2009) 1.03
Mesenchymal stem cells for ischemic stroke: changes in effects after ex vivo culturing. Cell Transplant (2008) 1.02
Free radical production in CA1 neurons induces MIP-1alpha expression, microglia recruitment, and delayed neuronal death after transient forebrain ischemia. J Neurosci (2008) 1.02
Neuroprotective effect of nicotine on dopaminergic neurons by anti-inflammatory action. Eur J Neurosci (2007) 1.02
Induction of neuronal death by microglial AGE-albumin: implications for Alzheimer's disease. PLoS One (2012) 1.01
[A case of Fitz-Hugh-Curtis syndrome in a male]. Korean J Gastroenterol (2010) 1.01