Published in J Virol on June 01, 1976
Herpes simplex virus gene expression in transformed cells. I. Regulation of the viral thymidine kinase gene in transformed L cells by products of superinfecting virus. J Virol (1976) 3.94
Tumorigenic transformation induced by a specific fragment of DNA from herpes simplex virus type 2. Proc Natl Acad Sci U S A (1980) 1.66
Transformation of rodent cells by a cloned DNA fragment of herpes simplex virus type 2. J Virol (1981) 1.54
Bovine papilloma virus: presence of virus-specific DNA sequences in naturally occurring equine tumors. Proc Natl Acad Sci U S A (1977) 1.45
Identification of proteins encoded by a fragment of herpes simplex virus type 2 DNA that has transforming activity. J Virol (1982) 1.42
Small fragments of herpesvirus DNA with transforming activity contain insertion sequence-like structures. Proc Natl Acad Sci U S A (1984) 1.34
Expression of an early, nonstructural antigen of herpes simplex virus in cell transformed in vitro by herpes simplex virus. J Virol (1977) 1.33
Analysis of viral DNA sequences in hamster cells transformed by herpes simplex virus type 2. Proc Natl Acad Sci U S A (1980) 1.16
Neoplastic transformation of cultured Syrian hamster embryo cells by DNA of herpes simplex virus type 2. J Virol (1979) 1.05
Adenovirus type 12 DNA sequences in primary hamster tumors. J Virol (1977) 0.91
The roles of viruses in brain tumor initiation and oncomodulation. J Neurooncol (2011) 0.88
Some aspects of the role of viruses in cancer. Postgrad Med J (1979) 0.83
Detection of herpes simplex virus type 2 glycoproteins expressed in virus-transformed rat cells. J Virol (1982) 0.82
Herpesvirus-specific RNA and protein in carcinoma of the uterine cervix. Proc Natl Acad Sci U S A (1982) 0.80
Thymidine kinaseless revertants of Ltk- cells transformed by herpes simplex virus type 1 are resistant to retransformation by homologous virus. Infect Immun (1977) 0.78
Retention of herpes simplex virus type II sequences in bglII n-transformed cells after co-transfection with a selectable marker. EMBO J (1985) 0.77
Effect of actinomycin D on the expression of herpes simplex virus-common surface antigen in cells transformed by herpes simplex virus type 2. J Virol (1979) 0.77
Herpes simplex virus (type 1) thymidine kinase gene does not transform cells morphologically. Proc Natl Acad Sci U S A (1981) 0.76
Mechanisms of expression of herpes simplex virus-common surface antigens in clonal cells of a herpes simplex virus type 2-transformed line. J Virol (1981) 0.75
Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms. Science (1968) 30.37
Size, composition, and structure of the deoxyribonucleic acid of herpes simplex virus subtypes 1 and 2. J Virol (1971) 17.07
A freeze-squeeze method for recovering long DNA from agarose gels. Anal Biochem (1975) 11.28
Anatomy of herpes simplex virus DNA. II. Size, composition, and arrangement of inverted terminal repetitions. J Virol (1975) 9.49
A crude nuclease preparation suitable for use in DNA reassociation experiments. Biochim Biophys Acta (1971) 7.92
Studies on in vitro transformation by DNA and DNA fragments of human adenoviruses and simian virus 40. Cold Spring Harb Symp Quant Biol (1975) 7.76
Transcription of Simian virus 40. I. Separation of the strands of SV40 DNA and hybridization of the separated strands to RNA extracted from lytically infected and transformed cells. J Mol Biol (1972) 7.49
Homology between Epstein-Barr virus DNA and viral DNA from Burkitt's lymphoma and nasopharyngeal carcinoma determined by DNA-DNA reassociation kinetics. Nature (1973) 6.68
Transfer of thymidine kinase to thymidine kinaseless L cells by infection with ultraviolet-irradiated herpes simplex virus. J Virol (1971) 5.13
Anatomy of herpes simplex virus DNA: strain differences and heterogeneity in the locations of restriction endonuclease cleavage sites. Proc Natl Acad Sci U S A (1975) 4.79
Viral DNA in transformed cells. II. A study of the sequences of adenovirus 2 DNA IN NINE LINES OF TRANSFORMED RAT CELLS USING SPECIFIC FRAGMENTS OF THE VIRAL GENOME;. J Mol Biol (1974) 4.39
Viral DNA in transformed cells. I. A study of the sequences of adenovirus 2 DNA in a line of transformed rat cells using specific fragments of the viral genome. J Mol Biol (1974) 4.30
Polykaryocytosis. Cold Spring Harb Symp Quant Biol (1962) 4.26
Anatomy of herpes simplex virus DNA. III. Characterization of defective DNA molecules and biological properties of virus populations containing them. J Virol (1975) 4.19
Properties of hamster embryo fibroblasts transformed in vitro after exposure to ultraviolet-irradiated herpes simplex virus type 2. J Virol (1971) 4.09
Anatomy of herpes simplex virus DNA. V. Terminally repetitive sequences. J Virol (1976) 3.56
Defective virions of herpes simplex viruses. Intervirology (1973) 3.03
Characterization of defective interfering viral particles present in a population of pseudorabies virions. Virology (1974) 2.66
Viral DNA sequences in cells transformed by simian virus 40, adenovirus type 2 and adenovirus type 5. Cold Spring Harb Symp Quant Biol (1975) 2.65
A DNA fragment of Herpes simplex 2 and its transcription in human cervical cancer tissue. Proc Natl Acad Sci U S A (1972) 2.45
Oncogenic transformation of hamster embryo cells after exposure to inactivated herpes simplex virus type 1. J Virol (1973) 2.44
Herpesvirus antigens on cell membranes detected by centrifugation of membrane-antibody complexes. Science (1971) 2.19
Transcription of simian virus 40. II. Hybridization of RNA extracted from different lines of transformed cells to the separated strands of simian virus 40 DNA. J Virol (1973) 2.08
Herpes simplex virus as a source of thymidine kinase for thymidine kinase-deficient mouse cells: suppression and reactivation of the viral enzyme. Proc Natl Acad Sci U S A (1973) 1.87
Analysis of DNA of defective herpes simplex virus type 1 by restriction endonuclease cleavage and nucleic acid hybridization. Cold Spring Harb Symp Quant Biol (1975) 1.69
Transformation of hamster embryo and human embryo cells by temperature sensitive mutants of herpes simplex virus type 2. Virology (1974) 1.64
Viral DNA in transformed cells. III. The amounts of different regions of the SV40 genome present in a line of transformed mouse cells. Proc Natl Acad Sci U S A (1974) 1.57
A transcriptional map of the SV40 genome in transformed cell lines. Virology (1975) 1.49
METAPHASE CHROMOSOMES AS A SOURCE OF DNA. Biochim Biophys Acta (1964) 1.18
Cells transformed by human Herpesvirus type 2 transcribe virus-specific RNA sequences shared by Herpesvirus types 1 and 2. Nat New Biol (1973) 1.10
Epstein-Barr virus in human tumor cells. Int Rev Exp Pathol (1972) 1.08
The host DNA sequences in different populations of serially passaged SV40. Virology (1974) 1.04
Attempts to detect virus-specific DNA in human tumors. II. Nucleic acid hybridizations with complementary RNA of human herpes group viruses. Int J Cancer (1974) 1.00
Transformation of hamster embryo fibroblasts by herpes simplex viruses type 1 and type 2. Cancer Res (1973) 0.97
Herpesviruses and cancer. Adv Cancer Res (1974) 0.82
Comparative pathology of cells transformed by herpes simplex virus type 1 or type 2. J Natl Cancer Inst (1974) 0.79
Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cells. J Gen Virol (1968) 26.67
Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins. J Virol (1974) 26.25
Proteins specified by herpes simplex virus. V. Purification and structural proteins of the herpesvirion. J Virol (1972) 17.28
Size, composition, and structure of the deoxyribonucleic acid of herpes simplex virus subtypes 1 and 2. J Virol (1971) 17.07
Proteins specified by herpes simplex virus. XII. The virion polypeptides of type 1 strains. J Virol (1974) 16.33
Proteins specified by herpes simplex virus. XI. Identification and relative molar rates of synthesis of structural and nonstructural herpes virus polypeptides in the infected cell. J Virol (1973) 12.48
Proteins specified by herpes simplex virus. 8. Characterization and composition of multiple capsid forms of subtypes 1 and 2. J Virol (1972) 11.71
Regulation of alpha genes of herpes simplex virus: expression of chimeric genes produced by fusion of thymidine kinase with alpha gene promoters. Cell (1981) 11.62
Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides. Proc Natl Acad Sci U S A (1975) 11.52
Anatomy of herpes simplex virus (HSV) DNA. X. Mapping of viral genes by analysis of polypeptides and functions specified by HSV-1 X HSV-2 recombinants. J Virol (1978) 11.19
Anatomy of herpes simplex virus DNA: evidence for four populations of molecules that differ in the relative orientations of their long and short components. Proc Natl Acad Sci U S A (1975) 10.59
Anatomy of herpes simplex virus DNA. II. Size, composition, and arrangement of inverted terminal repetitions. J Virol (1975) 9.49
A generalized technique for deletion of specific genes in large genomes: alpha gene 22 of herpes simplex virus 1 is not essential for growth. Cell (1981) 8.56
Characterization of the herpes simplex virion-associated factor responsible for the induction of alpha genes. J Virol (1983) 8.31
Regulation of herpesvirus macromolecular synthesis. V. Properties of alpha polypeptides made in HSV-1 and HSV-2 infected cells. Virology (1977) 8.24
Molecular genetics of herpes simplex virus. II. Mapping of the major viral glycoproteins and of the genetic loci specifying the social behavior of infected cells. J Virol (1979) 8.05
Preparation of herpes simplex virus of high titer. J Virol (1968) 7.64
Structural features of the herpes simplex virus alpha gene 4, 0, and 27 promoter-regulatory sequences which confer alpha regulation on chimeric thymidine kinase genes. J Virol (1982) 7.35
The structure and isomerization of herpes simplex virus genomes. Cell (1979) 6.79
Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture. Science (1990) 6.70
Cloning of reiterated and nonreiterated herpes simplex virus 1 sequences as BamHI fragments. Proc Natl Acad Sci U S A (1980) 6.66
The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase. Proc Natl Acad Sci U S A (1997) 6.08
Anatomy of herpes simplex virus DNA. IX. Apparent exclusion of some parental DNA arrangements in the generation of intertypic (HSV-1 X HSV-2) recombinants. J Virol (1977) 5.98
Regulation of herpesvirus macromolecular synthesis: nuclear retention of nontranslated viral RNA sequences. Proc Natl Acad Sci U S A (1974) 5.96
Proteins specified by herpes simplex virus. Staining and radiolabeling properties of B capsid and virion proteins in polyacrylamide gels. J Virol (1974) 5.74
Herpes simplex virus phosphoproteins. I. Phosphate cycles on and off some viral polypeptides and can alter their affinity for DNA. J Virol (1980) 5.69
Anatomy of herpes simplex virus DNA VII. alpha-RNA is homologous to noncontiguous sites in both the L and S components of viral DNA. J Virol (1977) 5.31
BamI, KpnI, and SalI restriction enzyme maps of the DNAs of herpes simplex virus strains Justin and F: occurrence of heterogeneities in defined regions of the viral DNA. J Virol (1979) 5.14
Genetic relatedness of type 1 and type 2 herpes simplex viruses. J Virol (1972) 5.11
The herpes simplex virus amplicon: a new eucaryotic defective-virus cloning-amplifying vector. Cell (1982) 5.10
Ribonucleic acid synthesis in cells infected with herpes simplex virus: controls of transcription and of RNA abundance. Proc Natl Acad Sci U S A (1972) 5.02
Proteins specified by herpes simplex virus. 3. Viruses differing in their effects on the social behavior of infected cells specify different membrane glycoproteins. Proc Natl Acad Sci U S A (1970) 4.97
Similarities and Differences in the Development of Laboratory Strains and Freshly Isolated Strains of Herpes Simplex Virus in HEp-2 Cells: Electron Microscopy. J Virol (1969) 4.94
The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells. Proc Natl Acad Sci U S A (1992) 4.90
Differentiation between alpha promoter and regulator regions of herpes simplex virus 1: the functional domains and sequence of a movable alpha regulator. Proc Natl Acad Sci U S A (1982) 4.84
Anatomy of herpes simplex virus DNA: strain differences and heterogeneity in the locations of restriction endonuclease cleavage sites. Proc Natl Acad Sci U S A (1975) 4.79
Regulation of herpesvirus macromolecular synthesis: transcription-initiation sites and domains of alpha genes. Proc Natl Acad Sci U S A (1980) 4.75
Proteins specified by herpes simplex virus. VI. Viral proteins in the plasma membrane. J Virol (1972) 4.57
Molecular engineering of the herpes simplex virus genome: insertion of a second L-S junction into the genome causes additional genome inversions. Cell (1980) 4.47
Herpes simplex virus infections. Lancet (2001) 4.41
Characterization of herpes simplex virus 1 alpha proteins 0, 4, and 27 with monoclonal antibodies. J Virol (1984) 4.37
Structure and role of the herpes simplex virus DNA termini in inversion, circularization and generation of virion DNA. Cell (1982) 4.36
Molecular genetics of herpes simplex virus: demonstration of regions of obligatory and nonobligatory identity within diploid regions of the genome by sequence replacement and insertion. Proc Natl Acad Sci U S A (1978) 4.31
Herpes simplex virus 1 alpha regulatory protein ICP0 interacts with and stabilizes the cell cycle regulator cyclin D3. J Virol (1997) 4.26
Polysomes and protein synthesis in cells infected with a DNA virus. Science (1966) 4.21
Anatomy of herpes simplex virus DNA. III. Characterization of defective DNA molecules and biological properties of virus populations containing them. J Virol (1975) 4.19
Herpes simplex virus 1 mutant deleted in the alpha 22 gene: growth and gene expression in permissive and restrictive cells and establishment of latency in mice. J Virol (1985) 4.17
Entry of herpes simplex virus 1 in BJ cells that constitutively express viral glycoprotein D is by endocytosis and results in degradation of the virus. J Virol (1988) 4.11
Properties of hamster embryo fibroblasts transformed in vitro after exposure to ultraviolet-irradiated herpes simplex virus type 2. J Virol (1971) 4.09
Separation of sequences defining basal expression from those conferring alpha gene recognition within the regulatory domains of herpes simplex virus 1 alpha genes. Proc Natl Acad Sci U S A (1984) 4.05
The promoter, transcriptional unit, and coding sequence of herpes simplex virus 1 family 35 proteins are contained within and in frame with the UL26 open reading frame. J Virol (1991) 4.01
Herpes vimplex virus: genome size and redundancy studied by renaturation kinetics. J Virol (1971) 3.92
Infection with herpes-simplex viruses 1 and 2. 3. N Engl J Med (1973) 3.89
Binding of the virion protein mediating alpha gene induction in herpes simplex virus 1-infected cells to its cis site requires cellular proteins. Proc Natl Acad Sci U S A (1987) 3.87
The herpes simplex virus 1 gene encoding a protease also contains within its coding domain the gene encoding the more abundant substrate. J Virol (1991) 3.80
Processing of the herpes simplex virus regulatory protein alpha 22 mediated by the UL13 protein kinase determines the accumulation of a subset of alpha and gamma mRNAs and proteins in infected cells. Proc Natl Acad Sci U S A (1993) 3.77
Herpes simplex virus-infected cells contain a function(s) that destabilizes both host and viral mRNAs. Proc Natl Acad Sci U S A (1987) 3.75
Nucleotide sequence and predicted amino acid sequence of a protein encoded in a small herpes simplex virus DNA fragment capable of trans-inducing alpha genes. Proc Natl Acad Sci U S A (1985) 3.75
Oncogenic transformation of hamster cells after exposure to herpes simplex virus type 2. Nat New Biol (1971) 3.73
Replication of herpes simplex virus DNA: localization of replication recognition signals within defective virus genomes. Proc Natl Acad Sci U S A (1981) 3.69
Association of a M(r) 90,000 phosphoprotein with protein kinase PKR in cells exhibiting enhanced phosphorylation of translation initiation factor eIF-2 alpha and premature shutoff of protein synthesis after infection with gamma 134.5- mutants of herpes simplex virus 1. Proc Natl Acad Sci U S A (1995) 3.68
Anatomy of the herpes simplex virus 1 strain F glycoprotein B gene: primary sequence and predicted protein structure of the wild type and of monoclonal antibody-resistant mutants. J Virol (1985) 3.67
Alpha 4, the major regulatory protein of herpes simplex virus type 1, is stably and specifically associated with promoter-regulatory domains of alpha genes and of selected other viral genes. Proc Natl Acad Sci U S A (1986) 3.64
The terminal a sequence of the herpes simplex virus genome contains the promoter of a gene located in the repeat sequences of the L component. J Virol (1986) 3.63
Anatomy of herpes simplex virus DNA. V. Terminally repetitive sequences. J Virol (1976) 3.56
A glucagonoma syndrome. Lancet (1974) 3.56
Development of a high-throughput quantitative assay for detecting herpes simplex virus DNA in clinical samples. J Clin Microbiol (1999) 3.48
Clustering of genes dispensable for growth in culture in the S component of the HSV-1 genome. Science (1987) 3.45
Site-specific inversion sequence of the herpes simplex virus genome: domain and structural features. Proc Natl Acad Sci U S A (1981) 3.45
Herpesvirus-dependent amplification and inversion of cell-associated viral thymidine kinase gene flanked by viral a sequences and linked to an origin of viral DNA replication. Proc Natl Acad Sci U S A (1982) 3.44
Malignant transformation of hamster embryo fibroblasts following exposure to ultraviolet-irradiated human cytomegalovirus. Virology (1973) 3.43
Herpes simplex virus phosphoproteins. II. Characterization of the virion protein kinase and of the polypeptides phosphorylated in the virion. J Virol (1980) 3.31
Cannabis use and risk of lung cancer: a case-control study. Eur Respir J (2008) 3.29
Regulation of alpha genes of herpes simplex virus: the alpha 27 gene promoter-thymidine kinase chimera is positively regulated in converted L cells. J Virol (1982) 3.28
Herpes simplex virus virion host shutoff function. J Virol (1988) 3.22
Site-specific cleavage/packaging of herpes simplex virus DNA and the selective maturation of nucleocapsids containing full-length viral DNA. Proc Natl Acad Sci U S A (1982) 3.21
The herpes simplex virus 1 gene for ICP34.5, which maps in inverted repeats, is conserved in several limited-passage isolates but not in strain 17syn+. J Virol (1990) 3.16
The open reading frames UL3, UL4, UL10, and UL16 are dispensable for the replication of herpes simplex virus 1 in cell culture. J Virol (1991) 3.13
Herpes simplex virus 1 protein kinase is encoded by open reading frame US3 which is not essential for virus growth in cell culture. J Virol (1987) 3.09
The effectiveness of breast cancer screening by mammography in younger women. Online J Curr Clin Trials (1993) 3.06
The herpes simplex virus 1 protein kinase encoded by the US3 gene mediates posttranslational modification of the phosphoprotein encoded by the UL34 gene. J Virol (1991) 3.06
The UL20 gene of herpes simplex virus 1 encodes a function necessary for viral egress. J Virol (1991) 3.04
Restriction endonuclease fingerprinting of herpes simplex virus DNA: a novel epidemiological tool applied to a nosocomial outbreak. J Infect Dis (1978) 3.00
Concerning the egress of herpes simplex virus from infected cells: electron and light microscope observations. Virology (1969) 2.99
The herpes simplex virus 1 protein kinase US3 is required for protection from apoptosis induced by the virus. Proc Natl Acad Sci U S A (1997) 2.98