Published in J Virol on June 01, 1971
Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1. Proc Natl Acad Sci U S A (1981) 10.04
Cloning of the active thymidine kinase gene of herpes simplex virus type 1 in Escherichia coli K-12. Proc Natl Acad Sci U S A (1979) 7.24
Hybrid plasmids containing an active thymidine kinase gene of Herpes simplex virus 1. Nucleic Acids Res (1979) 5.55
[125I]deoxycytidine used in a rapid, sensitive, and specific assay for herpes simplex virus type 1 thymidine kinase. J Virol (1977) 4.88
Construction and isolation of a transmissible retrovirus containing the src gene of Harvey murine sarcoma virus and the thymidine kinase gene of herpes simplex virus type 1. J Virol (1981) 4.54
Transfer of the gene for thymidine kinase to thymidine kinase-deficient human cells by purified herpes simplex viral DNA. Proc Natl Acad Sci U S A (1977) 4.35
Stable expression in mouse cells of nuclear neoantigen after transfer of a 3.4-megadalton cloned fragment of Epstein-Barr virus DNA. Proc Natl Acad Sci U S A (1982) 4.23
Polymorphic proteins encoded within BZLF1 of defective and standard Epstein-Barr viruses disrupt latency. J Virol (1987) 4.12
Properties of hamster embryo fibroblasts transformed in vitro after exposure to ultraviolet-irradiated herpes simplex virus type 2. J Virol (1971) 4.09
Herpes simplex virus gene expression in transformed cells. I. Regulation of the viral thymidine kinase gene in transformed L cells by products of superinfecting virus. J Virol (1976) 3.94
Persistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins. J Virol (1998) 2.97
Temperature-sensitive mutants of herpes simplex virus type 1 defective in lysis but not in transformation. J Virol (1975) 2.92
Two Epstein-Barr viral nuclear neoantigens distinguished by gene transfer, serology, and chromosome binding. Proc Natl Acad Sci U S A (1983) 2.68
Oncogenic transformation of hamster embryo cells after exposure to inactivated herpes simplex virus type 1. J Virol (1973) 2.44
Identification of Epstein-Barr nuclear antigen polypeptide in mouse and monkey cells after gene transfer with a cloned 2.9-kilobase-pair subfragment of the genome. Proc Natl Acad Sci U S A (1984) 2.32
Antiviral activity of arabinosylthymine in herpesviral replication: mechanism of action in vivo and in vitro. Antimicrob Agents Chemother (1977) 2.28
Virus type-specific thymidine kinase in cells biochemically transformed by herpes simplex virus types 1 and 2. J Virol (1974) 2.16
Expression of the viral thymidine kinase gene in herpes simplex virus-transformed L cells. J Virol (1974) 2.15
Selective assay for herpes simplex viruses expressing thymidine kinase. J Virol (1979) 2.03
Herpes simplex virus as a source of thymidine kinase for thymidine kinase-deficient mouse cells: suppression and reactivation of the viral enzyme. Proc Natl Acad Sci U S A (1973) 1.87
Identification and mapping of two polypeptides encoded within the herpes simplex virus type 1 thymidine kinase gene sequences. J Virol (1981) 1.83
Control of expression of the vaccinia virus thymidine kinase gene. J Virol (1981) 1.60
Nucleosomal packaging of the thymidine kinase gene of herpes simplex virus transferred into mouse cells: an actively expressed single-copy gene. Proc Natl Acad Sci U S A (1980) 1.53
Functional interactions between herpes simplex virus immediate-early proteins during infection: gene expression as a consequence of ICP27 and different domains of ICP4. J Virol (1995) 1.48
Expression of adenovirus E1a and E1b gene products and the Escherichia coli XGPRT gene in KB cells. J Virol (1983) 1.39
Herpes simplex virus DNA in transformed cells: sequence complexity in five hamster cell lines and one derived hamster tumor. J Virol (1976) 1.39
Expression of an early, nonstructural antigen of herpes simplex virus in cell transformed in vitro by herpes simplex virus. J Virol (1977) 1.33
Quantitation of the viral DNA present in cells transformed by UV-irradiated herpes simplex virus. J Virol (1976) 1.31
Identification of an Epstein-Barr virus-coded thymidine kinase. EMBO J (1986) 1.31
In vitro transcription of the thymidine kinase gene of herpes simplex virus. Proc Natl Acad Sci U S A (1982) 1.31
Neoplasms, differentiations and mutations. Am J Pathol (1974) 1.30
Depressed immunity and the development of cancer. Clin Exp Immunol (1981) 1.17
Identification of the herpes simplex virus DNA sequences present in six herpes simplex virus thymidine kinase-transformed mouse cell lines. J Virol (1980) 1.13
The William Allan Memorial Award Address: Gene clusters, Genome organization, and complex phenotypes. When the sequence is known, what will it mean? Am J Hum Genet (1981) 1.11
Location and cloning of the herpes simplex virus type 2 thymidine kinase gene. J Virol (1980) 1.11
Aanlysis of dCMP deaminase and CDP reductase levels in hamster cells infected by herpes simplex virus. J Virol (1978) 1.08
Transformation of cultured mammalian cells by viable herpes simplex virus subtypes 1 and 2. Proc Natl Acad Sci U S A (1974) 1.08
Biochemical and immunological characterization of deoxythymidine kinase of thymidine kinaseless HeLa cells biochemically transformed by herpes simplex virus type. Infect Immun (1977) 1.08
Induction of deoxycytidine deaminase activity in mammalian cell lines by infection with herpes simplex virus type 1. Proc Natl Acad Sci U S A (1977) 1.05
Identification of a glucocorticoid-responsive element in Epstein-Barr virus. J Virol (1990) 1.05
Host range temperature-sensitive mutants of herpes simplex virus type 2. J Virol (1976) 1.05
Presence of herpes simplex virus-related antigens in transformed L cells. J Virol (1975) 1.02
Temperature-sensitive host range mutants of herpes simplex virus type 2. J Virol (1975) 1.02
Quantitative assay for transformation of 3T3 cells by herpes simplex virus type 2. J Virol (1975) 1.00
Transduction of the Chinese hamster ovary aprt gene by herpes simplex virus. J Virol (1984) 0.96
Factors governing expression of the herpes simplex virus gene for thymidine kinase in clonal derivatives of transformed mouse L cells. J Virol (1981) 0.94
Biochemical transformation of deoxythymidine kinase-deficient mouse cells with UV-irradiated equine herpesvirus type 1. J Virol (1978) 0.90
Beneficial effects of human viruses. Yale J Biol Med (1981) 0.89
Biochemical transformation by temperature-sensitive mutants of herpes simplex virus type 1. J Virol (1980) 0.88
Inhibition of herpes simplex virus type 1 replication in temperature-sensitive cell cycle mutants. J Virol (1978) 0.87
Consequences of herpes simplex virus type 2 and human cell interaction at supraoptimal temperatures. J Virol (1976) 0.83
Biochemical characterization of equine herpesvirus type 3-induced deoxythymidine kinase purified from lytically infected horse embryo dermal fibroblasts. J Virol (1980) 0.82
Purification and biochemical characterization of deoxythymidine kinase of deoxythymidine kinase-deficient mouse 3T3 cells biochemically transformed by equine herpesvirus type 1. Infect Immun (1979) 0.82
Adenovirus late sequences linked to herpes simplex virus thymidine kinase may be introduced into eukaryotic cells and transcribed. Nucleic Acids Res (1981) 0.81
Cell mediated immunity to herpesvirus type 1 in carcinoma and pre-cancerous lesions. Br J Cancer Suppl (1973) 0.79
Are viruses important in carcinogenesis? Am J Pathol (1974) 0.78
Thymidine kinaseless revertants of Ltk- cells transformed by herpes simplex virus type 1 are resistant to retransformation by homologous virus. Infect Immun (1977) 0.78
Properties of cells carrying the herpes simplex virus type 2 thymidine kinase gene: mechanisms of reversion to a thymidine kinase-negative phenotype. J Virol (1980) 0.77
Binding to chromosomes of herpes simplex-related antigens in biochemically transformed cells. Proc Natl Acad Sci U S A (1978) 0.77
Effect of actinomycin D on the expression of herpes simplex virus-common surface antigen in cells transformed by herpes simplex virus type 2. J Virol (1979) 0.77
Herpes simplex virus (type 1) thymidine kinase gene does not transform cells morphologically. Proc Natl Acad Sci U S A (1981) 0.76
Thymidine kinase of mouse spleen cells in vivo and in vitro. Biochem J (1975) 0.75
Site of latent herpes. Br Med J (1973) 0.75
Cross-reacting herpes simplex virus antigens in hamster and mouse cells transformed by ultraviolet light-inactivated herpes simplex virus type 2. Infect Immun (1976) 0.75
Inhibition of herpes simplex virus type 2-induced biochemical transformation by interferon. J Virol (1980) 0.75
Gene and virotherapy for hematological malignancies. Int J Hematol (2016) 0.75
Inhibition of mouse LM cell replication by trifluorothymidine: role of cytosolic deoxythymidine kinase. Antimicrob Agents Chemother (1981) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
Amino acid metabolism in mammalian cell cultures. Science (1959) 55.21
DELETION OF THYMIDINE KINASE ACTIVITY FROM L CELLS RESISTANT TO BROMODEOXYURIDINE. Exp Cell Res (1963) 11.23
Herpes-type virus and chromosome marker in normal leukocytes after growth with irradiated Burkitt cells. Science (1967) 8.62
MUTANT STRAINS OF HERPES SIMPLEX DEFICIENT IN THYMIDINE KINASE-INDUCING ACTIVITY. Virology (1964) 6.69
Electron microscopic observations on the development of herpes simplex virus. J Exp Med (1959) 6.59
Transformation of foetal human keukocytes in vitro by filtrates of a human leukaemic cell line containing herpes-like virus. Int J Cancer (1968) 6.29
Herpes simplex virus DNA. Virology (1968) 5.65
Radiological evidence for partial genetic homology between bacteriophage and host bacteria. Virology (1955) 5.51
A virus-specific thymidine kinase in BHK-21 cells infected with herpes simplex virus. Virology (1967) 5.22
Presence of EB virus nucleic acid homology in a "virus-free" line of Burkitt tumour cells. Nature (1970) 4.41
A physical difference between two strains of herpes simplex virus apparent on sedimentation in cesium chloride. Virology (1961) 4.38
Acquisition of thymidine kinase activity by herpes simplex-infected mouse fibroblast cells. Biochem Biophys Res Commun (1963) 3.62
Agent of Marek's disease in tissue culture. Nature (1967) 3.05
Incidence of EB virus-containing cells in primary and secondary clones of several Burkitt lymphoma cell lines. Cancer Res (1970) 2.99
Electron microscopic particle counts on herpes virus using the phosphotungstate negative staining technique. Virology (1963) 2.94
THE INOSINIC ACID PYROPHOSPHORYLASE ACTIVITY OF MOUSE FIBROBLASTS PARTIALLY RESISTANT TO 8-AZAGUANINE. Proc Natl Acad Sci U S A (1963) 2.75
THE INDUCTION AND REPRESSION OF THYMIDINE KINASE IN THE POXVIRUS-INFECTED HELA CELL. Virology (1963) 2.72
STUDIES ON THYMIDINE KINASE IN CULTURED MOUSE FIBROBLASTS. Biochim Biophys Acta (1965) 2.47
Isolation and characterization of thymidine transport mutants of Chinese hamster cells. Exp Cell Res (1969) 2.27
The feedback inhibition of thymidine kinase. Biochim Biophys Acta (1963) 2.10
EFFECTS OF 5-FLUOROURACIL, ACTINOMYCIN D AND MITOMYCIN C ON THE INDUCTION OF THYMIDINE KINASE BY VACCINIA-INFECTED L-CELLS. J Mol Biol (1963) 1.29
Enhancement of viral transformation by ultra-violet light. Int J Radiat Biol Relat Stud Phys Chem Med (1970) 0.93
Rapid hypothesis testing with Candida albicans through gene disruption with short homology regions. J Bacteriol (1999) 10.31
Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis. Arthritis Rheum (1998) 8.69
Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids. Nature (1992) 7.02
Purification and cloning of amyloid precursor protein beta-secretase from human brain. Nature (1999) 5.77
RNA polymerase activity in purified infectious vaccinia virus. Proc Natl Acad Sci U S A (1967) 5.49
Strategies for reducing coronary heart disease and desirable limits for blood lipid concentrations: guidelines of the British Hyperlipidaemia Association. Br Med J (Clin Res Ed) (1987) 5.01
The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88. EMBO J (1997) 4.65
beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci (1992) 4.10
Scoring system to improve cost effectiveness of open access endoscopy. Br Med J (Clin Res Ed) (1983) 4.09
Independent regulatory elements in the nestin gene direct transgene expression to neural stem cells or muscle precursors. Neuron (1994) 4.00
Simplified method for dissolved DNA determination in aquatic environments. Appl Environ Microbiol (1986) 3.69
Food for New Zealanders. N Z Med J (1991) 3.59
Survival, functional limitations, and self-rated health in the NHANES I Epidemiologic Follow-up Study, 1992. First National Health and Nutrition Examination Survey. Am J Epidemiol (2000) 3.58
Risk of thrombosis in human atherosclerotic plaques: role of extracellular lipid, macrophage, and smooth muscle cell content. Br Heart J (1993) 3.54
Successful linkage of medical care and community services for HIV-positive offenders being released from prison. J Urban Health (2001) 3.49
Increased thrombotic vascular events after change of statin. Lancet (1998) 3.34
Esophageal dilation after laparoscopic adjustable gastric banding. Surg Endosc (2007) 3.27
Electrophoresis of thymidine kinase activity synthesized by cells transformed by herpes simplex virus. Virology (1972) 3.05
Synthesis and biophysical studies of short oligodeoxynucleotides with novel modifications: a possible approach to the problem of mixed base oligodeoxynucleotide synthesis. Nucleic Acids Res (1984) 3.00
A recyclable Candida albicans URA3 cassette for PCR product-directed gene disruptions. Yeast (2000) 2.90
Mortality in vegetarians and nonvegetarians: detailed findings from a collaborative analysis of 5 prospective studies. Am J Clin Nutr (1999) 2.78
Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis. J Immunol (1999) 2.74
Risk of death from cancer and ischaemic heart disease in meat and non-meat eaters. BMJ (1994) 2.70
Fatty acid composition of erythrocytes and plasma triglyceride and cardiovascular risk in Asian diabetic patients. Lancet (1994) 2.65
Dosage effects on gene expression in a maize ploidy series. Genetics (1996) 2.43
Nucleotide phosphohydrolase in purified vaccinia virus. J Virol (1968) 2.35
Diet, nutrition and the prevention of type 2 diabetes. Public Health Nutr (2004) 2.25
Brain aging and midlife tofu consumption. J Am Coll Nutr (2000) 2.25
Global surveillance and forecasting of AIDS. Bull World Health Organ (1989) 2.17
Fatal myocardial infarction and use of psychotropic drugs in young women. Lancet (1992) 2.16
Virus type-specific thymidine kinase in cells biochemically transformed by herpes simplex virus types 1 and 2. J Virol (1974) 2.16
Expression of the viral thymidine kinase gene in herpes simplex virus-transformed L cells. J Virol (1974) 2.15
Randomised controlled trial of effect of fruit and vegetable consumption on plasma concentrations of lipids and antioxidants. BMJ (1997) 2.04
Role of alpha9 nicotinic ACh receptor subunits in the development and function of cochlear efferent innervation. Neuron (1999) 2.01
Bacteria lacking a multidrug pump: a sensitive tool for drug discovery. Proc Natl Acad Sci U S A (1998) 2.01
Use of hypertonic saline in the treatment of severe refractory posttraumatic intracranial hypertension in pediatric traumatic brain injury. Crit Care Med (2000) 1.98
Screening for noninsulin dependent diabetes mellitus and impaired glucose tolerance in a Dunedin general practice--is it worth it? N Z Med J (1992) 1.93
Dietary intake and plasma lipid levels: lessons from a study of the diet of health conscious groups. BMJ (1990) 1.88
Neuromotor precursors of schizophrenia. Schizophr Bull (1994) 1.88
Assessing guidelines for use in family practice. J Fam Pract (2001) 1.87
Risk factors for fatal venous thromboembolism in young women: a case-control study. Int J Epidemiol (1992) 1.82
Condom use and HIV infection among prostitutes in Zaire. N Engl J Med (1987) 1.82
Air pollution and exacerbation of asthma in African-American children in Los Angeles. Epidemiology (2001) 1.81
Relocation of the carboxyterminal part of CAN from the nuclear envelope to the nucleus as a result of leukemia-specific chromosome rearrangements. Oncogene (1995) 1.78
Report on activities and attitudes of organizations active in the clinical practice guidelines field. CMAJ (1995) 1.76
Successful use of oral diazoxide in the treatment of severe toxaemia of pregnancy. Br Med J (1972) 1.76
Dilated cardiomyopathy is associated with an increase in the type I/type III collagen ratio: a quantitative assessment. J Am Coll Cardiol (1995) 1.75
Pharmacokinetics and dosage recommendations for an oseltamivir oral suspension for the treatment of influenza in children. Paediatr Drugs (2001) 1.74
Choosing among health insurance options: a study of new employees. Inquiry (1990) 1.72
American families with Crohn's disease have strong evidence for linkage to chromosome 16 but not chromosome 12. Gastroenterology (1998) 1.71
Identification and typing of herpes simplex viruses with monoclonal antibodies. J Clin Microbiol (1982) 1.68
The effects of the AIDS epidemic on the tuberculosis problem and tuberculosis programmes. Bull Int Union Tuberc Lung Dis (1988) 1.66
Methodology and feasibility of a home-based examination in disabled older women: the Women's Health and Aging Study. J Gerontol A Biol Sci Med Sci (1997) 1.66
Immunosuppressive and monooxygenase induction activities of polychlorinated diphenyl ether congeners in C57BL/6N mice: quantitative structure-activity relationships. Toxicol Appl Pharmacol (1990) 1.65
Altered water metabolism in tuberculosis: role of vasopressin. Am J Med (1990) 1.60
Subclavian arterial injury associated with blunt trauma. Vasc Surg (2001) 1.56
Gamma interferon (IFN-gamma) receptor null-mutant mice are more susceptible to herpes simplex virus type 1 infection than IFN-gamma ligand null-mutant mice. J Virol (1999) 1.54
Major depression and all-cause mortality among white adults in the United States. Ann Epidemiol (1997) 1.50
Comparison of two azithromycin distribution strategies for controlling trachoma in Nepal. Bull World Health Organ (2003) 1.49
Presence of a herpes simplex virus DNA fragment in an L cell clone obtained after infection with irradiated herpes simplex virus I. J Mol Biol (1975) 1.49
Magnetic resonance imaging of children without sedation: preparation with simulation. J Am Acad Child Adolesc Psychiatry (1997) 1.46
Heart transplantation for tumor. Ann Thorac Surg (1993) 1.44
Effect of malnutrition at the time of diagnosis on the survival of children treated for cancer in El Salvador and Northern Brazil. J Pediatr Hematol Oncol (2000) 1.44
Kinetics and free energy gaps of electron-transfer reactions in Rhodobacter sphaeroides reaction centers. Biochemistry (1993) 1.43
Comprehensive MR imaging protocol for stroke management: tissue sodium concentration as a measure of tissue viability in nonhuman primate studies and in clinical studies. Radiology (1999) 1.42
Clinical anatomy of the atrioventricular junctions. J Am Coll Cardiol (1994) 1.41
Mice transgenic for human carcinoembryonic antigen as a model for immunotherapy. Cancer Res (1998) 1.40
Linkage heterogeneity for the IBD1 locus in Crohn's disease pedigrees by disease onset and severity. Gastroenterology (2000) 1.40
Human carbonyl reductase overexpression in the heart advances the development of doxorubicin-induced cardiotoxicity in transgenic mice. Cancer Res (2000) 1.39
Should folate be added to flour to prevent neural tube defects? N Z Med J (1998) 1.39
Dietary management of patients with familial hypercholesterolaemia treated with simvastatin. Q J Med (1993) 1.39
Food for New Zealanders. N Z Med J (1993) 1.39
Mouse model for the lysosomal disorder galactosialidosis and correction of the phenotype with overexpressing erythroid precursor cells. Genes Dev (1995) 1.37
Oedema Disease (Entero-Toxaemia) In Swine-II. Experiments Conducted In A Susceptible Herd. Can J Comp Med Vet Sci (1955) 1.37
Endoplasmic reticulum dynamics, inheritance, and cytoskeletal interactions in budding yeast. Mol Biol Cell (2002) 1.37
Virulence of a live dengue virus vaccine candidate: a possible new marker of dengue virus attenuation. J Infect Dis (1988) 1.37
Physical activity patterns associated with cardiorespiratory fitness and reduced mortality: the Aerobics Center Longitudinal Study. Am J Public Health (1998) 1.36
Magnetic resonance imaging detects suppression of tumor vascular permeability after administration of antibody to vascular endothelial growth factor. Cancer Invest (1998) 1.36
Solid phase synthesis of somatostatin-28. Biochem Biophys Res Commun (1980) 1.34
The longitudinal course of recurrent affective illness: life chart data from research patients at the NIMH. Acta Psychiatr Scand Suppl (1985) 1.31
A randomized controlled trial assessing the impact of problem-based versus didactic teaching methods in CME. Res Med Educ (1988) 1.28
The osteoarthritis initiative (OAI) magnetic resonance imaging quality assurance methods and results. Osteoarthritis Cartilage (2008) 1.27
15N-labeled Escherichia coli tRNAfMet, tRNAGlu, tRNATyr, and tRNAPhe. Double resonance and two-dimensional NMR of N1-labeled pseudouridine. J Biol Chem (1985) 1.27
Cardiac rehabilitation as secondary prevention. Agency for Health Care Policy and Research and National Heart, Lung, and Blood Institute. Clin Pract Guidel Quick Ref Guide Clin (1995) 1.26
The nature of androgen action on male sexuality: a combined laboratory-self-report study on hypogonadal men. J Clin Endocrinol Metab (1983) 1.25
Growth and intracellular development of a new respiratory virus. J Virol (1967) 1.23
New insights into the epidemiology of childhood atopic dermatitis. Allergy (2013) 1.22
Effects of illness attribution and depression on the quality of life among persons with serious mental illness. Soc Sci Med (1994) 1.22
The impact of reference pricing on clinical lipid control. N Z Med J (1998) 1.20
beta-chemokines and neutralizing antibody titers correlate with sterilizing immunity generated in HIV-1 vaccinated macaques. Proc Natl Acad Sci U S A (1998) 1.20
Acute fluoride poisoning in a New Mexico elementary school. Pediatrics (1980) 1.20
Social evolution in toothed whales. Trends Ecol Evol (1998) 1.20
Pathogenesis of FOLFOX induced sinusoidal obstruction syndrome in a murine chemotherapy model. J Hepatol (2013) 1.20
Assessment of the biological and pharmacological effects of the alpha nu beta3 and alpha nu beta5 integrin receptor antagonist, cilengitide (EMD 121974), in patients with advanced solid tumors. Ann Oncol (2007) 1.19
Diazepam and lidocaine plasma protein binding in renal disease. Clin Pharmacol Ther (1982) 1.19
Quantitative tissue sodium concentration mapping of the growth of focal cerebral tumors with sodium magnetic resonance imaging. Magn Reson Med (1999) 1.18