Published in Proc Natl Acad Sci U S A on April 01, 1980
Identification of kaposin (open reading frame K12) as a human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus) transforming gene. J Virol (1998) 2.02
Transformation of NIH 3T3 cells with cloned fragments of human cytomegalovirus strain AD169. J Virol (1982) 1.88
Transformation of rodent cells by a cloned DNA fragment of herpes simplex virus type 2. J Virol (1981) 1.54
Characterization of mRNAs that map in the BglII N fragment of the herpes simplex virus type 2 genome. J Virol (1984) 1.54
DNA sequence homology between two co-linear loci on the HSV genome which have different transforming abilities. EMBO J (1983) 1.52
Identification of proteins encoded by a fragment of herpes simplex virus type 2 DNA that has transforming activity. J Virol (1982) 1.42
Herpes simplex virus specifies two subunits of ribonucleotide reductase encoded by 3'-coterminal transcripts. J Virol (1986) 1.39
Small fragments of herpesvirus DNA with transforming activity contain insertion sequence-like structures. Proc Natl Acad Sci U S A (1984) 1.34
Identification of a virus-specific polypeptide associated with a transforming fragment (BglII-N) of herpes simplex virus type 2 DNA. J Virol (1981) 1.30
Neoplastic transformation by a cloned human cytomegalovirus DNA fragment uniquely homologous to one of the transforming regions of herpes simplex virus type 2. Proc Natl Acad Sci U S A (1983) 1.29
Protein kinase activity associated with the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10). J Virol (1989) 1.17
Organization of the left-hand end of the herpes simplex virus type 2 BglII N fragment. J Virol (1984) 1.15
Identification of immediate-early-type cis-response elements in the promoter for the ribonucleotide reductase large subunit from herpes simplex virus type 2. J Virol (1989) 1.04
Immortalization and neoplastic transformation of normal diploid cells by defined cloned DNA fragments of herpes simplex virus type 2. Proc Natl Acad Sci U S A (1983) 1.04
Multiple transforming regions of human cytomegalovirus DNA. J Virol (1986) 1.03
Cellular proteins expressed in herpes simplex virus transformed cells also accumulate on herpes simplex virus infection. EMBO J (1985) 0.99
Cervical cancer: is herpes simplex virus type II a cofactor? Clin Microbiol Rev (1995) 0.99
DNA amplification and neoplastic transformation mediated by a herpes simplex DNA fragment containing cell-related sequences. Proc Natl Acad Sci U S A (1986) 0.98
Localization and comparative nucleotide sequence analysis of the transforming domain in herpes simplex virus DNA containing repetitive genetic elements. Proc Natl Acad Sci U S A (1986) 0.95
Multistep transformation by defined fragments of herpes simplex virus type 2 DNA: oncogenic region and its gene product. Proc Natl Acad Sci U S A (1985) 0.93
Detection by RNA blot hybridization of RNA sequences homologous to the BglII-N fragment of herpes simplex virus type 2 DNA. J Virol (1982) 0.93
Detection of herpes simplex virus type-2 DNA restriction fragments in human cervical carcinoma tissue. EMBO J (1983) 0.89
Focus formation and neoplastic transformation by herpes simplex virus type 2 inactivated intracellularly by 5-bromo-2'-deoxyuridine and near UV light. J Virol (1981) 0.88
Characterization of the novel protein kinase activity present in the R1 subunit of herpes simplex virus ribonucleotide reductase. J Virol (1995) 0.85
Herpes simplex virus type 2 mutagenesis: characterization of mutants induced at the hprt locus of nonpermissive XC cells. Mol Cell Biol (1986) 0.84
Detection of herpes simplex virus type 2 glycoproteins expressed in virus-transformed rat cells. J Virol (1982) 0.82
Herpesvirus-specific RNA and protein in carcinoma of the uterine cervix. Proc Natl Acad Sci U S A (1982) 0.80
Retention of herpes simplex virus type II sequences in bglII n-transformed cells after co-transfection with a selectable marker. EMBO J (1985) 0.77
Herpes simplex virus (type 1) thymidine kinase gene does not transform cells morphologically. Proc Natl Acad Sci U S A (1981) 0.76
Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol (1975) 503.08
Nucleotide sequence of the rightward operator of phage lambda. Proc Natl Acad Sci U S A (1975) 56.75
Anatomy of herpes simplex virus (HSV) DNA. X. Mapping of viral genes by analysis of polypeptides and functions specified by HSV-1 X HSV-2 recombinants. J Virol (1978) 11.19
The structure and isomerization of herpes simplex virus genomes. Cell (1979) 6.79
The transfer and stable integration of the HSV thymidine kinase gene into mouse cells. Cell (1978) 6.38
Anatomy of herpes simplex virus DNA. IX. Apparent exclusion of some parental DNA arrangements in the generation of intertypic (HSV-1 X HSV-2) recombinants. J Virol (1977) 5.98
Anatomy of herpes simplex virus DNA: strain differences and heterogeneity in the locations of restriction endonuclease cleavage sites. Proc Natl Acad Sci U S A (1975) 4.79
A new method for the isolation of herpes simplex virus type 2 DNA. Virology (1976) 4.61
Transformation of hamster embryo fibroblasts by a specific fragment of the herpes simplex virus genome. Cell (1978) 2.34
Herpes simplex virus DNA in transformed cells: sequence complexity in five hamster cell lines and one derived hamster tumor. J Virol (1976) 1.39
Antibody to HSV-2 induced tumor specific antigens in serums from patients with cervical carcinoma. Science (1973) 1.12
Neoplastic transformation of cultured Syrian hamster embryo cells by DNA of herpes simplex virus type 2. J Virol (1979) 1.05
Oncogenic transformation of rat embryo fibroblasts with photoinactivated herpes simplex virus: rapid in vitro cloning of transformed cells. J Gen Virol (1977) 0.98
Immunodiagnostic potential of a virus-coded, tumor-associated antigen (AG-4) in cervical cancer. Cancer (1977) 0.97
Experimental evidence for the oncogenic potential of herpes simplex virus. Cancer Res (1976) 0.95
Biochemical studies on bovine adenovirus type 3. III. Cleavage maps of viral DNA by restriction endoncleases EcoRI, BamHI, and HindIII. J Virol (1978) 0.94
Proteins of herpesvirus type 2. III. Isolation and immunologic characterization of a large molecular weight viral protein. Virology (1978) 0.94
Proteins of herpesvirus type 2. II. Studies demonstrating a correlation between a tumor-associated antigen (AG-4) and a virion protein. Virology (1976) 0.92
Biologic and immunologic comparison of two HSV-2 variants: one an isolate from cervical tumor cells. Arch Gesamte Virusforsch (1974) 0.88
Antiviral effect of an oligo(nucleoside methylphosphonate) complementary to the splice junction of herpes simplex virus type 1 immediate early pre-mRNAs 4 and 5. Proc Natl Acad Sci U S A (1986) 4.92
Biochemical and biological effects of nonionic nucleic acid methylphosphonates. Biochemistry (1981) 3.08
Hybridization arrest of globin synthesis in rabbit reticulocyte lysates and cells by oligodeoxyribonucleoside methylphosphonates. Biochemistry (1985) 2.60
Nonionic nucleic acid analogues. Synthesis and characterization of dideoxyribonucleoside methylphosphonates. Biochemistry (1979) 2.57
Control of ribonucleic acid function by oligonucleoside methylphosphonates. Biochimie (1986) 2.43
Inhibition of vesicular stomatitis virus protein synthesis and infection by sequence-specific oligodeoxyribonucleoside methylphosphonates. Biochemistry (1986) 2.26
Selective inhibition of Escherichia coli protein synthesis and growth by nonionic oligonucleotides complementary to the 3' end of 16S rRNA. Proc Natl Acad Sci U S A (1981) 2.20
The association of genital herpesvirus with cervical atypia and carcinoma in situ. Am J Epidemiol (1970) 2.17
Syntheses and properties of adenine and thymine nucleoside alkyl phosphotriesters, the neutral analogs of dinucleoside monophosphates. J Am Chem Soc (1971) 2.14
Evidence for the progressive nature of neoplastic transformation in vitro. Proc Natl Acad Sci U S A (1978) 2.00
Conformation and interaction of short nucleic acid double-stranded helices. I. Proton magnetic resonance studies on the nonexchangeable protons of ribosyl ApApGpCpUpU. Biochemistry (1975) 1.79
Duplex formation of a nonionic oligo(deoxythymidylate) analogue (heptadeoxythymidylyl-(3'-5')-deoxythymidine heptaethyl ester (d-(Tp(Et))7T)) with poly(deoxyadenylate). Evaluation of the electrostatic interaction. Biochemistry (1977) 1.78
Role of superoxide in deoxyribonucleic acid strand scission. Biochemistry (1980) 1.70
Effects of a trinucleotide ethyl phosphotriester, Gmp(Et)Gmp(Et)U, on mammalian cells in culture. Biochemistry (1977) 1.69
Virus-specific immunity in neonatal and adult mouse rotavirus infection. Infect Immun (1983) 1.60
The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) blocks apoptosis in hippocampal neurons, involving activation of the MEK/MAPK survival pathway. J Virol (2002) 1.54
Site specificity of the inhibitory effects of oligo(nucleoside methylphosphonate)s complementary to the acceptor splice junction of herpes simplex virus type 1 immediate early mRNA 4. Proc Natl Acad Sci U S A (1989) 1.54
Ring-current effects in the Nmr of nucleic acids: a graphical approach. Biopolymers (1976) 1.52
Preparation of oligodeoxyribonucleoside methylphosphonates on a polystyrene support. Nucleic Acids Res (1983) 1.51
Synthesis of oligodeoxyribonucleotide ethyl phosphotriesters and their specific complex formation with transfer ribonucleic acid. Biochemistry (1974) 1.49
Preparation of a decadeoxyribonucleotide helix for studies by nuclear magnetic resonance. Biochemistry (1980) 1.47
Interaction and association of bases and nucleosides in aqueous solutions. IV. Proton magnetic resonance studies of the association of pyrimidine nucleosides and their interactions with purine. J Am Chem Soc (1965) 1.45
A new approach to chemotherapy based on molecular biology and nucleic acid chemistry: Matagen (masking tape for gene expression). Anticancer Drug Des (1987) 1.43
Proton nuclear magnetic resonance studies on dideoxyribonucleoside methylphosphonates. Biochemistry (1980) 1.42
Studies of the conformation and interaction in dinucleoside mono- and diphosphates by proton magnetic resonance. Biochemistry (1969) 1.42
Identification and characterization of circulating prostate carcinoma cells. Cancer (2000) 1.41
Antisense inhibition of ras p21 expression that is sensitive to a point mutation. Biochemistry (1991) 1.39
Structural requirements of the rI n -rC n complex for induction of human interferon. J Mol Biol (1972) 1.33
Antibody to genital herpes simplex virus: association with cervical atypia and carcinoma in situ. J Natl Cancer Inst (1970) 1.32
Temporal acquistion of enhanced fibrinolytic activity by syrian hamster embryo cells following treatment with benzo(a)pyrene. Cancer Res (1977) 1.31
Studies of inter- and intramolecular interaction in mononucleotides by proton magnetic resonance. J Am Chem Soc (1968) 1.31
Neoplastic transformation by a cloned human cytomegalovirus DNA fragment uniquely homologous to one of the transforming regions of herpes simplex virus type 2. Proc Natl Acad Sci U S A (1983) 1.29
Nuclear Overhauser effect as a tool for the complete assignment of nonexchangeable proton resonances in short deoxyribonucleic acid helices. Biochemistry (1983) 1.25
Interaction of poly-L-lysine and nucleic acids. J Mol Biol (1966) 1.25
Immunofluorescent detection of herpesvirus antigens in exfoliated cells from human cervical carcinoma. Proc Natl Acad Sci U S A (1970) 1.25
Immunity to herpes simplex virus type 2. IV. Impaired lymphokine production during recrudescence correlates with an imbalance in T lymphocyte subsets. J Immunol (1982) 1.24
Prevention of rotavirus-induced diarrhea in neonatal mice born to dams immunized with empty capsids of simian rotavirus SA-11. J Infect Dis (1984) 1.23
Possible role of Herpesvirus hominis, type 2, in human cervical cancer. Fed Proc (1973) 1.22
Proteins of herpesvirus type 2: I. Virion, nonvirion, and antigenic polypeptides in infected cells. Virology (1976) 1.21
Use of EDTA derivatization to characterize interactions between oligodeoxyribonucleoside methylphosphonates and nucleic acids. Biochemistry (1989) 1.18
RNA polymerase from Micrococcus luteus: comparative effect of ribosyl and deoxyribosyl oligomers on the homopolymer. Directed reaction. Biochem Biophys Res Commun (1971) 1.18
L'adenylyl-(3'-5')-L-adenosine and L-adenylyl-(2'-5')-L-adenosine. Biochemistry (1970) 1.17
Protein kinase activity associated with the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10). J Virol (1989) 1.17
Herpesvirus type 2 isolated from cervical tumor cells grown in tissue culture. Science (1971) 1.17
An alternative view of mammalian DNA sequence organization. II. Short repetitive sequences are organized into scrambled tandem clusters in Syrian hamster DNA. J Mol Biol (1981) 1.15
Synthesis and properties of the dinucleoside monophosphate of adenine 8-thiocyclonucleoside. J Am Chem Soc (1972) 1.15
Herpes simplex virus associated erythema multiforme (HAEM) is mechanistically distinct from drug-induced erythema multiforme: interferon-gamma is expressed in HAEM lesions and tumor necrosis factor-alpha in drug-induced erythema multiforme lesions. J Invest Dermatol (1999) 1.14
Neoplastic transformation induced by a direct perturbation of DNA. Nature (1978) 1.14
Antibody to HSV-2 induced tumor specific antigens in serums from patients with cervical carcinoma. Science (1973) 1.12
Erythema multiforme lesions are associated with expression of a herpes simplex virus (HSV) gene and qualitative alterations in the HSV-specific T-cell response. Br J Dermatol (1998) 1.12
A novel procedure for the synthesis of 2'-O-alkyl nucleotides. Biochemistry (1972) 1.12
Activation of 2',5'-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells by 2'-O-methylated poly (inosinic acid) . poly(cytidylic acid), Correlations with interferon-inducing activity. J Biol Chem (1980) 1.11
Correlation of in vitro growth properties and tumorigenicity of Syrian hamster cell lines. Cancer Res (1979) 1.10
Relationship between somatic mutation and neoplastic transformation. Proc Natl Acad Sci U S A (1978) 1.09
Immunity to herpes simplex virus type 2: recurrent lesions are associated with the induction of suppressor cells and soluble suppressor factors. Infect Immun (1983) 1.09
Cellulose acetate phthalate (CAP): an 'inactive' pharmaceutical excipient with antiviral activity in the mouse model of genital herpesvirus infection. Antivir Chem Chemother (1999) 1.07
A mammalian cellular system for the concomitant study of neoplastic transformation and somatic mutation. Mutat Res (1978) 1.07
Conformation and interaction of short nucleic acid double-stranded helices. II. Proton magnetic resonance studies on the hydrogen-bonded NH-N protons of ribosyl ApApGpCpUpU helix. Biochemistry (1975) 1.07
Quantitation of fibrinolytic activity of Syrian hamster fibroblasts using 3H-labeled fibrinogen prepared by reductive alkylation. Cancer Res (1977) 1.07
Localization and DNA sequence analysis of the transforming domain (mtrII) of human cytomegalovirus. Proc Natl Acad Sci U S A (1988) 1.07
Proton nuclear magnetic resonance study of a self-complementary decadeoxyribonucleotide, C-C-A-A-G-C-T-T-G-G. Biochemistry (1982) 1.07
Influence of the furanose on the conformation of adenine dinucleoside monophosphates in solution. Biochemistry (1972) 1.06
1H nuclear magnetic resonance studies of transfer RNA: the methyl and methylene resonances of baker's yeast phenylalanine transfer RNA and its fragments. Biochemistry (1977) 1.06
A probabilistic analysis of DNA sequence organization. J Mol Biol (1981) 1.06
Conformational properties of the furanose phosphate backbone in nucleic acids. A carbon-13 nuclear magnetic resonance study. Biochemistry (1977) 1.05
Demonstration by plaque reduction technique of immunologic relationship between canine herpes virus and herpes simplex virus. Proc Soc Exp Biol Med (1968) 1.05
Neoplastic transformation of cultured Syrian hamster embryo cells by DNA of herpes simplex virus type 2. J Virol (1979) 1.05
Identification of immediate-early-type cis-response elements in the promoter for the ribonucleotide reductase large subunit from herpes simplex virus type 2. J Virol (1989) 1.04
Immortalization and neoplastic transformation of normal diploid cells by defined cloned DNA fragments of herpes simplex virus type 2. Proc Natl Acad Sci U S A (1983) 1.04
Suppression of human immunodeficiency virus replication by ascorbate in chronically and acutely infected cells. Proc Natl Acad Sci U S A (1990) 1.03
A truncated protein kinase domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) expressed in Escherichia coli. J Biol Chem (1991) 1.02
Proton magnetic resonance studies on the conformation of the hexanucleotide, GmpApApYpApsiP, and Related fragments from the anticodong loop of baker's yeast phenylalanine transfer ribonucleic acid. Biochemistry (1975) 1.00
Toxicity of metabolic benzo(a)pyrenediones to cultured cells and the dependence upon molecular oxygen. Cancer Res (1979) 0.99
The PK domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is required for immediate-early gene expression and virus growth. J Virol (1998) 0.99
Conformation of oligoinosinates: chain-length dependence and comparison to other oligonucleotides. Biochemistry (1972) 0.99
Viruses and gynecologic cancers: herpesvirus protein (ICP 10/AG-4), a cervical tumor antigen that fulfills the criteria for a marker of carcinogenicity. Cancer (1981) 0.99
Comparative circular dichroism and fluorescence studies of oligodeoxyribonucleotide and oligodeoxyribonucleoside methylphosphonate pyrimidine strands in duplex and triplex formation. Biochemistry (1991) 0.98
DNA amplification and neoplastic transformation mediated by a herpes simplex DNA fragment containing cell-related sequences. Proc Natl Acad Sci U S A (1986) 0.98
Interaction of nucleic acids. 8. Binding of magnesium ions by nucleic acids. J Mol Biol (1971) 0.98
Benzo[a]yrenedione/benzo[a]pyrenediol oxidation-reduction couples and the generation of reactive reduced molecular oxygen. Biochemistry (1977) 0.97
1H NMR studies of transfer RNA III: the observed and the computed spectra of the hydrogen-bonded NH resonances of baker's yeast transfer-RNA Phe. Nucleic Acids Res (1977) 0.97
Inhibition of RNA directed DNA polymerase of murine leukemia virus by 2'-O-alkylated polyadenylic acids. Biochem Biophys Res Commun (1974) 0.97
Immunodiagnostic potential of a virus-coded, tumor-associated antigen (AG-4) in cervical cancer. Cancer (1977) 0.97
Longitudinal study of a patient with herpes-simplex-virus-associated erythema multiforme: viral gene expression and T cell repertoire usage. Dermatology (1999) 0.97
Immunity to herpes simplex virus type 2: cell-mediated immunity in latently infected guinea pigs. Infect Immun (1980) 0.97
Inhibitory effect of complex formation with oligodeoxyribonucleotide ethyl phosphotriesters on transfer ribonucleic acid aminoacylation. Biochemistry (1974) 0.96
Herpesvirus type 2-related antigens and their relevance to humoral and cell-mediated immunity in patients with cervical cancer. Cancer Res (1976) 0.96
Interaction of nucleic acids. IV. The physical binding of 3,4-benzpyrene to nucleosides, nucleotides, nucleic acids, and nucleoprotein. Biochemistry (1968) 0.96
Contributions of the PO ester and CO torsion angles of the phosphate group to 31P-nuclear magnetic shielding constant in nucleic acids: theoretical and experimental study of model compounds. Biopolymers (1984) 0.96
Localization and comparative nucleotide sequence analysis of the transforming domain in herpes simplex virus DNA containing repetitive genetic elements. Proc Natl Acad Sci U S A (1986) 0.95