Published in Protein Expr Purif on August 24, 2007
Microbial production of plant benzylisoquinoline alkaloids. Proc Natl Acad Sci U S A (2008) 1.89
'Dopamine-first' mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile. FEBS J (2015) 0.88
Enzyme catalysed Pictet-Spengler formation of chiral 1,1'-disubstituted- and spiro-tetrahydroisoquinolines. Nat Commun (2017) 0.79
Enlarging the toolbox for allergen epitope definition with an allergen-type model protein. PLoS One (2014) 0.78
A NusE:NusG complex links transcription and translation. Science (2010) 3.03
Alkaloid biosynthesis: metabolism and trafficking. Annu Rev Plant Biol (2008) 2.09
Two structurally independent domains of E. coli NusG create regulatory plasticity via distinct interactions with RNA polymerase and regulators. J Mol Biol (2009) 1.85
Mutational epitope analysis of Pru av 1 and Api g 1, the major allergens of cherry (Prunus avium) and celery (Apium graveolens): correlating IgE reactivity with three-dimensional structure. Biochem J (2003) 1.72
Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy. Nat Chem Biol (2010) 1.39
Molecular cloning and characterization of norcoclaurine synthase, an enzyme catalyzing the first committed step in benzylisoquinoline alkaloid biosynthesis. Plant J (2004) 1.37
An α helix to β barrel domain switch transforms the transcription factor RfaH into a translation factor. Cell (2012) 1.35
Transcriptome analysis based on next-generation sequencing of non-model plants producing specialized metabolites of biotechnological interest. J Biotechnol (2013) 1.32
Got milk? The secret life of laticifers. Trends Plant Sci (2008) 1.31
A tale of three cell types: alkaloid biosynthesis is localized to sieve elements in opium poppy. Plant Cell (2003) 1.28
Benzylisoquinoline alkaloid metabolism: a century of discovery and a brave new world. Plant Cell Physiol (2013) 1.21
Structural analysis of linear hydroxyproline-bound O-glycans of Chlamydomonas reinhardtii--conservation of the inner core in Chlamydomonas and land plants. Carbohydr Res (2007) 1.15
Mechanistic studies on norcoclaurine synthase of benzylisoquinoline alkaloid biosynthesis: an enzymatic Pictet-Spengler reaction. Biochemistry (2007) 1.15
Development of transcriptomic resources for interrogating the biosynthesis of monoterpene indole alkaloids in medicinal plant species. PLoS One (2012) 1.14
Molecular cloning and characterization of tetrahydroprotoberberine cis-N-methyltransferase, an enzyme involved in alkaloid biosynthesis in opium poppy. J Biol Chem (2007) 1.14
Quantitative 1H NMR metabolomics reveals extensive metabolic reprogramming of primary and secondary metabolism in elicitor-treated opium poppy cell cultures. BMC Plant Biol (2008) 1.14
Structure and stability of 2S albumin-type peanut allergens: implications for the severity of peanut allergic reactions. Biochem J (2006) 1.14
CD and NMR studies of prion protein (PrP) helix 1. Novel implications for its role in the PrPC-->PrPSc conversion process. J Biol Chem (2003) 1.13
Integration of deep transcriptome and proteome analyses reveals the components of alkaloid metabolism in opium poppy cell cultures. BMC Plant Biol (2010) 1.12
Structure and dynamics of helix-0 of the N-BAR domain in lipid micelles and bilayers. Biophys J (2008) 1.10
Quality assessment of ginseng by (1)H NMR metabolite fingerprinting and profiling analysis. J Agric Food Chem (2009) 1.08
Gene transcript and metabolite profiling of elicitor-induced opium poppy cell cultures reveals the coordinate regulation of primary and secondary metabolism. Planta (2006) 1.05
Fully metallated S134N Cu,Zn-superoxide dismutase displays abnormal mobility and intermolecular contacts in solution. J Biol Chem (2005) 1.05
Regulation of foamy virus protease activity by viral RNA: a novel and unique mechanism among retroviruses. J Virol (2011) 1.03
Domain interactions of the transcription-translation coupling factor Escherichia coli NusG are intermolecular and transient. Biochem J (2011) 1.03
The solution structure of the simian foamy virus protease reveals a monomeric protein. J Mol Biol (2008) 1.03
A stereoselective hydroxylation step of alkaloid biosynthesis by a unique cytochrome P450 in Catharanthus roseus. J Biol Chem (2011) 1.03
Integration of deep transcript and targeted metabolite profiles for eight cultivars of opium poppy. Plant Mol Biol (2012) 1.00
Plant defense responses in opium poppy cell cultures revealed by liquid chromatography-tandem mass spectrometry proteomics. Mol Cell Proteomics (2008) 0.99
Tissue-specific expression of FLOWERING LOCUS T in Arabidopsis is maintained independently of polycomb group protein repression. Plant Cell (2011) 0.99
NusA interaction with the α subunit of E. coli RNA polymerase is via the UP element site and releases autoinhibition. Structure (2011) 0.99
Purification and characterization of norcoclaurine synthase. The first committed enzyme in benzylisoquinoline alkaloid biosynthesis in plants. J Biol Chem (2002) 0.99
Evidence for the monophyletic evolution of benzylisoquinoline alkaloid biosynthesis in angiosperms. Phytochemistry (2005) 0.99
Systematic knockdown of morphine pathway enzymes in opium poppy using virus-induced gene silencing. Plant J (2011) 0.98
NMR solution structure of SlyD from Escherichia coli: spatial separation of prolyl isomerase and chaperone function. J Mol Biol (2009) 0.98
Structural characterization of Lyn-SH3 domain in complex with a herpesviral protein reveals an extended recognition motif that enhances binding affinity. Protein Sci (2005) 0.97
Sanguinarine biosynthesis is associated with the endoplasmic reticulum in cultured opium poppy cells after elicitor treatment. Plant Physiol (2005) 0.97
RNA-binding specificity of E. coli NusA. Nucleic Acids Res (2009) 0.97
Pipecolic acid derivatives as small-molecule inhibitors of the Legionella MIP protein. J Med Chem (2010) 0.96
Dioxygenases catalyze O-demethylation and O,O-demethylenation with widespread roles in benzylisoquinoline alkaloid metabolism in opium poppy. J Biol Chem (2013) 0.96
Evidence for the monophyletic evolution of benzylisoquinoline alkaloid biosynthesis in angiosperms. Phytochemistry (2005) 0.96
High-yield expression in Escherichia coli, purification, and characterization of properly folded major peanut allergen Ara h 2. Protein Expr Purif (2003) 0.95
Systematic silencing of benzylisoquinoline alkaloid biosynthetic genes reveals the major route to papaverine in opium poppy. Plant J (2012) 0.95
AZT resistance of simian foamy virus reverse transcriptase is based on the excision of AZTMP in the presence of ATP. Nucleic Acids Res (2007) 0.95
Biophysical and enzymatic properties of the simian and prototype foamy virus reverse transcriptases. Retrovirology (2010) 0.95
Crystal structure of the human transcription elongation factor DSIF hSpt4 subunit in complex with the hSpt5 dimerization interface. Biochem J (2009) 0.95
Binding, domain orientation, and dynamics of the Lck SH3-SH2 domain pair and comparison with other Src-family kinases. Biochemistry (2005) 0.95
The solution structure of a chimeric LEKTI domain reveals a chameleon sequence. Biochemistry (2004) 0.94
Removal of substrate inhibition and increase in maximal velocity in the short chain dehydrogenase/reductase salutaridine reductase involved in morphine biosynthesis. J Biol Chem (2009) 0.94
Cure and curse: E. coli heat-stable enterotoxin and its receptor guanylyl cyclase C. Toxins (Basel) (2010) 0.94
Targeted metabolite and transcript profiling for elucidating enzyme function: isolation of novel N-methyltransferases from three benzylisoquinoline alkaloid-producing species. Plant J (2009) 0.94
Structural studies on the RNA-recognition motif of NELF E, a cellular negative transcription elongation factor involved in the regulation of HIV transcription. Biochem J (2006) 0.93
Biochemistry and occurrence of o-demethylation in plant metabolism. Front Physiol (2010) 0.93
Characterization of three O-methyltransferases involved in noscapine biosynthesis in opium poppy. Plant Physiol (2012) 0.93
Quantitative 1H nuclear magnetic resonance metabolite profiling as a functional genomics platform to investigate alkaloid biosynthesis in opium poppy. Plant Physiol (2008) 0.93
Benzylisoquinoline alkaloid biosynthesis in opium poppy. Planta (2014) 0.92
Transcript and metabolite profiling in cell cultures of 18 plant species that produce benzylisoquinoline alkaloids. Phytochemistry (2012) 0.91
The role of E. coli Nus-factors in transcription regulation and transcription:translation coupling: From structure to mechanism. Transcription (2011) 0.91
Characterization of Lck-binding elements in the herpesviral regulatory Tip protein. Biochemistry (2004) 0.91
The E. coli NusA carboxy-terminal domains are structurally similar and show specific RNAP- and lambdaN interaction. Protein Sci (2005) 0.90
Interaction of the intrinsically unstructured phage lambda N Protein with Escherichia coli NusA. Biochemistry (2006) 0.90
Formation of transient dimers by a retroviral protease. Biochem J (2010) 0.89
Subcellular localization and integration activities of rous sarcoma virus reverse transcriptase. J Virol (2002) 0.89
The prototype foamy virus protease is active independently of the integrase domain. Retrovirology (2012) 0.89
Interpreting conformational effects in protein nano-ESI-MS spectra. Anal Bioanal Chem (2003) 0.89
Homologous proteins with different folds: the three-dimensional structures of domains 1 and 6 of the multiple Kazal-type inhibitor LEKTI. J Mol Biol (2003) 0.89
Putative aggregation initiation sites in prion protein. FEBS Lett (2006) 0.89
Conformation, catalytic site, and enzymatic mechanism of the PR10 allergen-related enzyme norcoclaurine synthase. Biochem J (2008) 0.88
The role of phloem sieve elements and laticifers in the biosynthesis and accumulation of alkaloids in opium poppy. Plant J (2006) 0.88
Evolution of morphine biosynthesis in opium poppy. Phytochemistry (2009) 0.87
Natural variation of H3K27me3 distribution between two Arabidopsis accessions and its association with flanking transposable elements. Genome Biol (2012) 0.87
Tyrosine aminotransferase contributes to benzylisoquinoline alkaloid biosynthesis in opium poppy. Plant Physiol (2011) 0.87
Energy landscape of the prion protein helix 1 probed by metadynamics and NMR. Biophys J (2012) 0.86
Evolutionary and cellular webs in benzylisoquinoline alkaloid biosynthesis. Curr Opin Biotechnol (2008) 0.86
Fine tuning of the E. coli NusB:NusE complex affinity to BoxA RNA is required for processive antitermination. Nucleic Acids Res (2009) 0.86