Published in Dev Biol on August 24, 2007
Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates. Dev Dyn (2013) 1.07
p160 Myb-binding protein interacts with Prep1 and inhibits its transcriptional activity. Mol Cell Biol (2007) 1.04
Induction of HoxB transcription by retinoic acid requires actin polymerization. Mol Biol Cell (2009) 1.03
Prep1 directly regulates the intrinsic apoptotic pathway by controlling Bcl-XL levels. Mol Cell Biol (2008) 1.01
Cytoplasmic Prep1 interacts with 4EHP inhibiting Hoxb4 translation. PLoS One (2009) 0.99
Homeodomain transcription factor and tumor suppressor Prep1 is required to maintain genomic stability. Proc Natl Acad Sci U S A (2011) 0.95
Cooperative transcriptional activation by Klf4, Meis2, and Pbx1. Mol Cell Biol (2011) 0.91
Cytosolic sequestration of Prep1 influences early stages of T cell development. PLoS One (2008) 0.86
Reduction of Prep1 levels affects differentiation of normal and malignant B cells and accelerates Myc driven lymphomagenesis. PLoS One (2012) 0.84
Acute molecular response of mouse hindlimb muscles to chronic stimulation. Am J Physiol Cell Physiol (2009) 0.83
An autoinhibitory effect of the homothorax domain of Meis2. FEBS J (2010) 0.80
ChIP-Seq and RNA-Seq analyses identify components of the Wnt and Fgf signaling pathways as Prep1 target genes in mouse embryonic stem cells. PLoS One (2015) 0.79
Zebrafish hoxd4a acts upstream of meis1.1 to direct vasculogenesis, angiogenesis and hematopoiesis. PLoS One (2013) 0.78
Prep1 (pKnox1) regulates mouse embryonic HSC cycling and self-renewal affecting the Stat1-Sca1 IFN-dependent pathway. PLoS One (2014) 0.78
Characterization of the regulatory region of the zebrafish Prep1.1 gene: analogies to the promoter of the human PREP1. PLoS One (2010) 0.76
The role of Pbx1 in T cells. Protein Cell (2011) 0.75
Loss of the Homeodomain Transcription Factor Prep1 Perturbs Adult Hematopoiesis in the Bone Marrow. PLoS One (2015) 0.75
The effect of telithromycin in acute exacerbations of asthma. N Engl J Med (2006) 5.35
Amoxicillin for acute lower-respiratory-tract infection in primary care when pneumonia is not suspected: a 12-country, randomised, placebo-controlled trial. Lancet Infect Dis (2012) 4.62
Hydrocortisone infusion for severe community-acquired pneumonia: a preliminary randomized study. Am J Respir Crit Care Med (2004) 4.58
Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells. Nat Med (2006) 3.11
Hot spots of retroviral integration in human CD34+ hematopoietic cells. Blood (2007) 2.79
Predicting Mycobacterium tuberculosis in patients with community-acquired pneumonia. Eur Respir J (2013) 2.69
Heated Humidified High-Flow Nasal Oxygen in Adults: Mechanisms of Action and Clinical Implications. Chest (2015) 2.66
Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination. Nat Cell Biol (2006) 2.40
Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets. Blood (2005) 2.39
Muscle-derived hematopoietic stem cells are hematopoietic in origin. Proc Natl Acad Sci U S A (2002) 2.39
Thrombocytopenia and thrombocytosis at time of hospitalization predict mortality in patients with community-acquired pneumonia. Chest (2009) 2.34
Anxiety and depression in COPD patients: The roles of gender and disease severity. Respir Med (2006) 2.28
Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation. Nat Cell Biol (2010) 2.25
The urokinase plasminogen activator system in cancer: recent advances and implication for prognosis and therapy. Cancer Metastasis Rev (2003) 2.22
Old ideas to innovate tuberculosis control: preventive treatment to achieve elimination. Eur Respir J (2013) 2.20
Impact of age and comorbidity on cause and outcome in community-acquired pneumonia. Chest (2013) 2.19
A worldwide perspective of atypical pathogens in community-acquired pneumonia. Am J Respir Crit Care Med (2007) 2.08
The European Respiratory Society plans its future: the 2013-2018 strategic plan. Eur Respir J (2014) 2.02
Stratifying risk factors for multidrug-resistant pathogens in hospitalized patients coming from the community with pneumonia. Clin Infect Dis (2011) 1.97
Risk factors for community-acquired pneumonia in adults in Europe: a literature review. Thorax (2013) 1.92
Involvement of the urokinase-type plasminogen activator receptor in hematopoietic stem cell mobilization. Blood (2004) 1.83
Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement. Nat Med (2002) 1.80
Hedgehog controls neural stem cells through p53-independent regulation of Nanog. EMBO J (2010) 1.73
Proapoptotic function of the retinoblastoma tumor suppressor protein. Cancer Cell (2009) 1.73
uPA and uPAR in fibrinolysis, immunity and pathology. Trends Immunol (2004) 1.71
The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells. Proc Natl Acad Sci U S A (2007) 1.68
REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma. Proc Natl Acad Sci U S A (2004) 1.63
Bone marrow as an alternative site for islet transplantation. Blood (2009) 1.61
Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression. Development (2006) 1.56
Assessment of severity of ICU-acquired pneumonia and association with etiology. Crit Care Med (2014) 1.53
Dimerization controls the lipid raft partitioning of uPAR/CD87 and regulates its biological functions. EMBO J (2003) 1.52
Acute myocardial infarction in hospitalized patients with community-acquired pneumonia. Clin Infect Dis (2008) 1.49
Bronchiectasis: an update. Clin Respir J (2009) 1.48
Validation of predictors of adverse outcomes in hospital-acquired pneumonia in the ICU. Crit Care Med (2013) 1.48
In vivo selection of genetically modified erythroblastic progenitors leads to long-term correction of beta-thalassemia. Proc Natl Acad Sci U S A (2008) 1.48
Role of atypical bacteria and azithromycin therapy for children with recurrent respiratory tract infections. Pediatr Infect Dis J (2005) 1.47
Transcription factor binding sites are genetic determinants of retroviral integration in the human genome. PLoS One (2009) 1.46
Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype. Mol Cell Biol (2006) 1.46
Adrenomedullin refines mortality prediction by the BODE index in COPD: the "BODE-A" index. Eur Respir J (2013) 1.45
Tuberculosis elimination: theory and practice in Europe. Eur Respir J (2014) 1.42
Multidrug-resistant pathogens in hospitalised patients coming from the community with pneumonia: a European perspective. Thorax (2013) 1.41
ICU-acquired pneumonia with or without etiologic diagnosis: a comparison of outcomes. Crit Care Med (2013) 1.41
Towards Microsurgical Correction of Cleft Lip Ex Utero via Restoration of Craniofacial Developmental Programs. Plast Reconstr Surg (2017) 1.39
Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2. Development (2011) 1.37
Domain 2 of the urokinase receptor contains an integrin-interacting epitope with intrinsic signaling activity: generation of a new integrin inhibitor. J Biol Chem (2005) 1.33
Quantitatively different red cell/nucleated cell chimerism in patients with long-term, persistent hematopoietic mixed chimerism after bone marrow transplantation for thalassemia major or sickle cell disease. Haematologica (2010) 1.32
Monomer dimer dynamics and distribution of GPI-anchored uPAR are determined by cell surface protein assemblies. J Cell Biol (2007) 1.30
Electronic cigarettes. A position statement of the forum of international respiratory societies. Am J Respir Crit Care Med (2014) 1.29
Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons. J Neurosci (2010) 1.26
A Pbx1-dependent genetic and transcriptional network regulates spleen ontogeny. Development (2005) 1.25
MicroRNAs as biomarkers for CNS cancer and other disorders. Brain Res (2010) 1.25
Deletion of TMPRSS6 attenuates the phenotype in a mouse model of β-thalassemia. Blood (2012) 1.25
Urokinase regulates vitronectin binding by controlling urokinase receptor oligomerization. J Biol Chem (2002) 1.25
Nanoparticle-based delivery of small interfering RNA: challenges for cancer therapy. Int J Nanomedicine (2012) 1.24
MicroRNA and proliferation control in chronic lymphocytic leukemia: functional relationship between miR-221/222 cluster and p27. Blood (2010) 1.22
The urokinase receptor as an entertainer of signal transduction. Front Biosci (Landmark Ed) (2009) 1.21
Analysis of the DNA-binding profile and function of TALE homeoproteins reveals their specialization and specific interactions with Hox genes/proteins. Cell Rep (2013) 1.21
Hedgehog antagonist REN(KCTD11) regulates proliferation and apoptosis of developing granule cell progenitors. J Neurosci (2005) 1.19
Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells. J Clin Invest (2009) 1.19
Lentiviral vector integration in the human genome induces alternative splicing and generates aberrant transcripts. J Clin Invest (2012) 1.19
Overexpression of PREP-1 in F9 teratocarcinoma cells leads to a functionally relevant increase of PBX-2 by preventing its degradation. J Biol Chem (2003) 1.19
Involvement of Prep1 in the alphabeta T-cell receptor T-lymphocytic potential of hematopoietic precursors. Mol Cell Biol (2005) 1.17
Expression of Hoxa2 in rhombomere 4 is regulated by a conserved cross-regulatory mechanism dependent upon Hoxb1. Dev Biol (2006) 1.17
Guidelines for empiric antimicrobial prescribing in community-acquired pneumonia. Chest (2004) 1.17
MAPK and JNK transduction pathways can phosphorylate Sp1 to activate the uPA minimal promoter element and endogenous gene transcription. Blood (2004) 1.15
Protein kinase A-mediated synapsin I phosphorylation is a central modulator of Ca2+-dependent synaptic activity. J Neurosci (2006) 1.15
An uncleavable uPAR mutant allows dissection of signaling pathways in uPA-dependent cell migration. Mol Biol Cell (2005) 1.15
Vismodegib, a small-molecule inhibitor of the hedgehog pathway for the treatment of advanced cancers. Curr Opin Investig Drugs (2010) 1.15
The soluble D2D3(88-274) fragment of the urokinase receptor inhibits monocyte chemotaxis and integrin-dependent cell adhesion. J Cell Sci (2004) 1.14
Hoxb1 enhancer and control of rhombomere 4 expression: complex interplay between PREP1-PBX1-HOXB1 binding sites. Mol Cell Biol (2005) 1.14
Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells. Proc Natl Acad Sci U S A (2013) 1.12
Follow-up of low risk patients with papillary thyroid cancer: role of neck ultrasonography in detecting lymph node metastases. J Clin Endocrinol Metab (2004) 1.12
Prep1.1 has essential genetic functions in hindbrain development and cranial neural crest cell differentiation. Development (2004) 1.12
Cup is a nucleocytoplasmic shuttling protein that interacts with the eukaryotic translation initiation factor 4E to modulate Drosophila ovary development. Proc Natl Acad Sci U S A (2004) 1.11
Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication. Virology (2013) 1.11
Correction of beta-thalassemia major by gene transfer in haematopoietic progenitors of pediatric patients. EMBO Mol Med (2010) 1.10
FOG1 requires NuRD to promote hematopoiesis and maintain lineage fidelity within the megakaryocytic-erythroid compartment. Blood (2010) 1.09
An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma. Neoplasia (2008) 1.09
Leukemogenesis induced by wild-type and STI571-resistant BCR/ABL is potently suppressed by C/EBPalpha. Blood (2006) 1.08
Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia. J Cereb Blood Flow Metab (2012) 1.08
Hox and Pbx factors control retinoic acid synthesis during hindbrain segmentation. Dev Cell (2011) 1.07
Inhibition of medulloblastoma tumorigenesis by the antiproliferative and pro-differentiative gene PC3. FASEB J (2007) 1.07
Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma. Neoplasia (2011) 1.07
Mesenchymal cells appearing in pancreatic tissue culture are bone marrow-derived stem cells with the capacity to improve transplanted islet function. Stem Cells (2010) 1.07
Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates. Dev Dyn (2013) 1.07
Prep1 deficiency induces protection from diabetes and increased insulin sensitivity through a p160-mediated mechanism. Mol Cell Biol (2008) 1.07
Inhibition of interleukin-8 (CXCL8/IL-8) responses by repertaxin, a new inhibitor of the chemokine receptors CXCR1 and CXCR2. Biochem Pharmacol (2004) 1.06
Clathrin and LRP-1-independent constitutive endocytosis and recycling of uPAR. PLoS One (2008) 1.06