Published in J Cell Sci on October 15, 2007
Environmental sensing through focal adhesions. Nat Rev Mol Cell Biol (2009) 9.56
TGF-beta-induced epithelial to mesenchymal transition. Cell Res (2009) 7.88
Dual-objective STORM reveals three-dimensional filament organization in the actin cytoskeleton. Nat Methods (2012) 2.67
Tissue elongation requires oscillating contractions of a basal actomyosin network. Nat Cell Biol (2010) 2.15
Movers and shakers: cell cytoskeleton in cancer metastasis. Br J Pharmacol (2014) 1.74
United we stand: integrating the actin cytoskeleton and cell-matrix adhesions in cellular mechanotransduction. J Cell Sci (2012) 1.63
Actin filaments function as a tension sensor by tension-dependent binding of cofilin to the filament. J Cell Biol (2011) 1.54
RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes. Mol Biol Cell (2011) 1.39
Role of DLC-1, a tumor suppressor protein with RhoGAP activity, in regulation of the cytoskeleton and cell motility. Cancer Metastasis Rev (2009) 1.36
Self-organization of engineered epithelial tubules by differential cellular motility. Proc Natl Acad Sci U S A (2009) 1.36
Conformational changes and signaling in cell and matrix physics. Curr Biol (2009) 1.33
Retrograde flow and myosin II activity within the leading cell edge deliver F-actin to the lamella to seed the formation of graded polarity actomyosin II filament bundles in migrating fibroblasts. Mol Biol Cell (2008) 1.30
Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration. BMC Biol (2011) 1.30
NMII forms a contractile transcellular sarcomeric network to regulate apical cell junctions and tissue geometry. Curr Biol (2013) 1.29
A dynamic stochastic model of frequency-dependent stress fiber alignment induced by cyclic stretch. PLoS One (2009) 1.27
Actin cross-link assembly and disassembly mechanics for alpha-Actinin and fascin. J Biol Chem (2010) 1.21
Cytoskeletal dynamics and spermatogenesis. Philos Trans R Soc Lond B Biol Sci (2010) 1.19
Risk assessment, disease prevention and personalised treatments in breast cancer: is clinically qualified integrative approach in the horizon? EPMA J (2013) 1.17
Rapid endothelial cytoskeletal reorganization enables early blood-brain barrier disruption and long-term ischaemic reperfusion brain injury. Nat Commun (2016) 1.14
ASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasion. J Biol Chem (2008) 1.12
A role for myosin II in mammalian mitochondrial fission. Curr Biol (2014) 1.12
Emergence of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin axis in transforming growth factor-β-induced epithelial-mesenchymal transition. Cells Tissues Organs (2010) 1.11
FHOD1 interaction with nesprin-2G mediates TAN line formation and nuclear movement. Nat Cell Biol (2014) 1.09
CRL2(LRR-1) targets a CDK inhibitor for cell cycle control in C. elegans and actin-based motility regulation in human cells. Dev Cell (2010) 1.09
Deleted in liver cancer 1 (DLC1) negatively regulates Rho/ROCK/MLC pathway in hepatocellular carcinoma. PLoS One (2008) 1.08
N-cadherin ligation, but not Sonic hedgehog binding, initiates Cdo-dependent p38alpha/beta MAPK signaling in skeletal myoblasts. Proc Natl Acad Sci U S A (2010) 1.07
Lipofuscin redistribution and loss accompanied by cytoskeletal stress in retinal pigment epithelium of eyes with age-related macular degeneration. Invest Ophthalmol Vis Sci (2015) 1.06
Striated acto-myosin fibers can reorganize and register in response to elastic interactions with the matrix. Biophys J (2011) 1.06
Cross-correlated TIRF/AFM reveals asymmetric distribution of force-generating heads along self-assembled, "synthetic" myosin filaments. Biophys J (2009) 1.05
Rho-associated kinase-dependent contraction of stress fibres and the organization of focal adhesions. J R Soc Interface (2010) 1.05
Dependence of myoblast fusion on a cortical actin wall and nonmuscle myosin IIA. Dev Biol (2008) 1.04
Multi-scale mechanics from molecules to morphogenesis. Int J Biochem Cell Biol (2009) 1.03
microRNA-124 inhibits migration and invasion by down-regulating ROCK1 in glioma. PLoS One (2013) 1.02
Clathrin-independent endocytosis of ErbB2 in geldanamycin-treated human breast cancer cells. J Cell Sci (2008) 1.02
Muscarinic receptor agonists stimulate human colon cancer cell migration and invasion. Am J Physiol Gastrointest Liver Physiol (2011) 1.01
Tiam1 and Rac1 are required for platelet-activating factor-induced endothelial junctional disassembly and increase in vascular permeability. J Biol Chem (2008) 1.00
Nanoparticle tension probes patterned at the nanoscale: impact of integrin clustering on force transmission. Nano Lett (2014) 1.00
Actin stress fibre subtypes in mesenchymal-migrating cells. Open Biol (2013) 0.99
Diversification of caldesmon-linked actin cytoskeleton in cell motility. Cell Adh Migr (2011) 0.99
Rearrangements of the actin cytoskeleton and E-cadherin-based adherens junctions caused by neoplasic transformation change cell-cell interactions. PLoS One (2009) 0.99
LKB1 tumor suppressor protein regulates actin filament assembly through Rho and its exchange factor Dbl independently of kinase activity. BMC Cell Biol (2010) 0.98
Polarity-regulating kinase partitioning-defective 1b (PAR1b) phosphorylates guanine nucleotide exchange factor H1 (GEF-H1) to regulate RhoA-dependent actin cytoskeletal reorganization. J Biol Chem (2011) 0.96
Actin cytoskeleton in myofibroblast differentiation: ultrastructure defining form and driving function. Transl Res (2011) 0.96
Mesenchymal stem cell mechanobiology and emerging experimental platforms. J R Soc Interface (2013) 0.96
Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancer. Pharmacol Rev (2014) 0.96
Identification of an FHL1 protein complex containing ACTN1, ACTN4, and PDLIM1 using affinity purifications and MS-based protein-protein interaction analysis. Mol Biosyst (2011) 0.95
The small GTPase Rif is an alternative trigger for the formation of actin stress fibers in epithelial cells. J Cell Sci (2010) 0.95
Important but differential roles for actin in trafficking of Epstein-Barr virus in B cells and epithelial cells. J Virol (2011) 0.94
The Rho kinase inhibitor Fasudil up-regulates astrocytic glutamate transport subsequent to actin remodelling in murine cultured astrocytes. Br J Pharmacol (2011) 0.93
MicroRNA-584 and the protein phosphatase and actin regulator 1 (PHACTR1), a new signaling route through which transforming growth factor-β Mediates the migration and actin dynamics of breast cancer cells. J Biol Chem (2013) 0.93
Regulation of integrin trafficking, cell adhesion, and cell migration by WASH and the Arp2/3 complex. Cytoskeleton (Hoboken) (2012) 0.92
How linear tension converts to curvature: geometric control of bone tissue growth. PLoS One (2012) 0.92
Junb regulates arterial contraction capacity, cellular contractility, and motility via its target Myl9 in mice. J Clin Invest (2010) 0.92
Actin binding proteins and spermiogenesis: Some unexpected findings. Spermatogenesis (2011) 0.91
Expression and function of matrix metalloproteinase (MMP)-28. Matrix Biol (2009) 0.91
Simvastatin induces apoptosis and alters cytoskeleton in endometrial stromal cells. J Clin Endocrinol Metab (2010) 0.91
Mechanochemical regulation of oscillatory follicle cell dynamics in the developing Drosophila egg chamber. Mol Biol Cell (2014) 0.91
KSHV-TK is a tyrosine kinase that disrupts focal adhesions and induces Rho-mediated cell contraction. EMBO J (2014) 0.90
Caveolin-1 induces formation of membrane tubules that sense actomyosin tension and are inhibited by polymerase I and transcript release factor/cavin-1. Mol Biol Cell (2010) 0.90
Myocilin, a glaucoma-associated protein, promotes cell migration through activation of integrin-focal adhesion kinase-serine/threonine kinase signaling pathway. J Cell Physiol (2011) 0.90
Mechanotransduction: use the force(s). BMC Biol (2015) 0.90
Protein kinase C, focal adhesions and the regulation of cell migration. J Histochem Cytochem (2013) 0.89
Involvement of local lamellipodia in endothelial barrier function. PLoS One (2015) 0.88
LIM proteins in actin cytoskeleton mechanoresponse. Trends Cell Biol (2014) 0.88
The retinoic acid inducible Cas-family signaling protein Nedd9 regulates neural crest cell migration by modulating adhesion and actin dynamics. Neuroscience (2009) 0.88
The Drosophila egg chamber-a new spin on how tissues elongate. Integr Comp Biol (2014) 0.88
Myozap, a novel intercalated disc protein, activates serum response factor-dependent signaling and is required to maintain cardiac function in vivo. Circ Res (2010) 0.88
Glucocorticoid receptor-mediated expression of caldesmon regulates cell migration via the reorganization of the actin cytoskeleton. J Biol Chem (2008) 0.87
Indole-3-carbinol inhibits MDA-MB-231 breast cancer cell motility and induces stress fibers and focal adhesion formation by activation of Rho kinase activity. Int J Cancer (2009) 0.87
A pathogenic relationship between a regulator of the actin cytoskeleton and serum response factor. Genetics (2010) 0.87
Genomic and proteomic studies on the effects of the insect growth regulator diflubenzuron in the model beetle species Tribolium castaneum. Insect Biochem Mol Biol (2011) 0.86
Optimization of Storage Temperature for Cultured ARPE-19 Cells. J Ophthalmol (2013) 0.86
Stromal regulation of embryonic and postnatal mammary epithelial development and differentiation. Semin Cell Dev Biol (2014) 0.86
Regulation of actin dynamics and protein trafficking during spermatogenesis--insights into a complex process. Crit Rev Biochem Mol Biol (2013) 0.86
Study of the actin cytoskeleton in live endothelial cells expressing GFP-actin. J Vis Exp (2011) 0.86
Slits affect the timely migration of neural crest cells via Robo receptor. Dev Dyn (2012) 0.86
Nanomechanics of vascular endothelium. Cell Tissue Res (2014) 0.86
A biomechanical perspective on stress fiber structure and function. Biochim Biophys Acta (2015) 0.85
Global architecture of the F-actin cytoskeleton regulates cell shape-dependent endothelial mechanotransduction. Integr Biol (Camb) (2014) 0.85
AKAP12 regulates vascular integrity in zebrafish. Exp Mol Med (2012) 0.85
Rho-associated kinase connects a cell cycle-controlling anchorage signal to the mammalian target of rapamycin pathway. J Biol Chem (2011) 0.85
The filament sensor for near real-time detection of cytoskeletal fiber structures. PLoS One (2015) 0.85
TGF-β autocrine pathway and MAPK signaling promote cell invasiveness and in vivo mammary adenocarcinoma tumor progression. Oncol Rep (2012) 0.84
Reflectivity and topography of cells grown on glass-coverslips measured with phase-shifted laser feedback interference microscopy. Biomed Opt Express (2011) 0.83
Modulation of Wound Healing and Scar Formation by MG53 Protein-mediated Cell Membrane Repair. J Biol Chem (2015) 0.83
A three-dimensional study of alveologenesis in mouse lung. Dev Biol (2015) 0.83
Enhanced ROCK1 dependent contractility in fibroblast from chronic obstructive pulmonary disease patients. J Transl Med (2012) 0.83
Genetic evidence for antagonism between Pak protein kinase and Rho1 small GTPase signaling in regulation of the actin cytoskeleton during Drosophila oogenesis. Genetics (2010) 0.83
Urokinase plasminogen activator receptor induced non-small cell lung cancer invasion and metastasis requires NHE1 transporter expression and transport activity. Cell Oncol (Dordr) (2012) 0.83
α-actinin1 and 4 tyrosine phosphorylation is critical for stress fiber establishment, maintenance and focal adhesion maturation. Exp Cell Res (2013) 0.83
Cell polarity signaling in the plasticity of cancer cell invasiveness. Oncotarget (2016) 0.82
Non-muscle myosin II induces disassembly of actin stress fibres independently of myosin light chain dephosphorylation. Interface Focus (2011) 0.82
Mechanical systems biology of C. elegans touch sensation. Bioessays (2015) 0.82
A collapsin response mediator protein 2 isoform controls myosin II-mediated cell migration and matrix assembly by trapping ROCK II. Mol Cell Biol (2012) 0.82
The N-BAR domain protein, Bin3, regulates Rac1- and Cdc42-dependent processes in myogenesis. Dev Biol (2013) 0.82
The role of cholesterol-sphingomyelin membrane nanodomains in the stability of intercellular membrane nanotubes. Int J Nanomedicine (2012) 0.82
Rotavirus infection of cells in culture induces activation of RhoA and changes in the actin and tubulin cytoskeleton. PLoS One (2012) 0.82
Simvastatin decreases invasiveness of human endometrial stromal cells. Biol Reprod (2012) 0.81
Myosin activity drives actomyosin bundle formation and organization in contractile cells of the C. elegans spermatheca. Mol Biol Cell (2017) 0.81
Histamine activates p38 MAP kinase and alters local lamellipodia dynamics, reducing endothelial barrier integrity and eliciting central movement of actin fibers. Am J Physiol Cell Physiol (2015) 0.81
Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high- curvature membranes and 3-phosphoinositides. Curr Biol (2004) 3.76
The Rho family GTPase Rif induces filopodia through mDia2. Curr Biol (2005) 2.58
RhoB and actin polymerization coordinate Src activation with endosome-mediated delivery to the membrane. Dev Cell (2004) 2.13
VEGF regulates the mobilization of VEGFR2/KDR from an intracellular endothelial storage compartment. Blood (2006) 1.87
Co-ordinate regulation of distinct host cell signalling pathways by multifunctional enteropathogenic Escherichia coli effector molecules. Mol Microbiol (2002) 1.71
Regulation of endocytic traffic by Rho GTPases. Biochem J (2003) 1.31
The Rho GTPase family: a Racs to Wrchs story. J Cell Sci (2002) 1.29
Farnesyltransferase inhibitors disrupt EGF receptor traffic through modulation of the RhoB GTPase. J Cell Sci (2004) 1.16
Synergistic roles for the Map and Tir effector molecules in mediating uptake of enteropathogenic Escherichia coli (EPEC) into non-phagocytic cells. Cell Microbiol (2003) 1.05
Rho GTPase activation assays. Curr Protoc Cell Biol (2008) 0.99
VEGF receptor trafficking in angiogenesis. Biochem Soc Trans (2009) 0.98
The small GTPase Rif is an alternative trigger for the formation of actin stress fibers in epithelial cells. J Cell Sci (2010) 0.95
VEGFR1 (Flt1) regulates Rab4 recycling to control fibronectin polymerization and endothelial vessel branching. Traffic (2009) 0.94
Small interfering RNAs as a tool to assign Rho GTPase exchange-factor function in vivo. Biochem J (2002) 0.94
RhoG protein regulates platelet granule secretion and thrombus formation in mice. J Biol Chem (2013) 0.90
The formin FMNL3 is a cytoskeletal regulator of angiogenesis. J Cell Sci (2012) 0.89
The small GTPase Rif is dispensable for platelet filopodia generation in mice. PLoS One (2013) 0.89
Uses of the in vitro endothelial-fibroblast organotypic co-culture assay in angiogenesis research. Biochem Soc Trans (2011) 0.85
Identification and characterization of a novel activated RhoB binding protein containing a PDZ domain whose expression is specifically modulated in thyroid cells by cAMP. Eur J Biochem (2002) 0.84
Farnesyltransferase inhibitors target multiple endothelial cell functions in angiogenesis. Angiogenesis (2008) 0.84
S1P and LPA trigger Schwann cell actin changes and migration. Eur J Neurosci (2004) 0.84
Translocation of the cell-penetrating Tat peptide across artificial bilayers and into living cells. Biochem Soc Symp (2005) 0.81
Escherichia coli isolated from bovine mastitis invade mammary cells by a modified endocytic pathway. Vet Microbiol (2008) 0.80
Site recognition and substrate screens for PKN family proteins. Biochem J (2011) 0.80
Scanning electron microscopy of cell surface morphology. Curr Protoc Cell Biol (2007) 0.79
The small Rho GTPase Rif and actin cytoskeletal remodelling. Biochem Soc Trans (2012) 0.79
RNA interference approaches to examine Golgi function in animal cell culture. Methods Cell Biol (2013) 0.75
The coculture organotypic assay of angiogenesis. Methods Mol Biol (2015) 0.75