Published in Biophys J on March 04, 2009
Imaging with total internal reflection fluorescence microscopy for the cell biologist. J Cell Sci (2010) 1.69
The power of correlative microscopy: multi-modal, multi-scale, multi-dimensional. Curr Opin Struct Biol (2011) 1.50
Mechanobiology of bone marrow stem cells: from myosin-II forces to compliance of matrix and nucleus in cell forms and fates. Differentiation (2013) 1.04
Combined optical and topographic imaging reveals different arrangements of human RAD54 with presynaptic and postsynaptic RAD51-DNA filaments. Proc Natl Acad Sci U S A (2013) 0.81
Spectroscopic investigation of local mechanical impedance of living cells. PLoS One (2014) 0.80
Structural basis for myopathic defects engendered by alterations in the myosin rod. J Mol Biol (2011) 0.79
Controlling the Electromagnetic Field Confinement with Metamaterials. Sci Rep (2016) 0.75
Far-field optical nanoscopy. Science (2007) 13.17
ELECTRON MICROSCOPE STUDIES ON THE STRUCTURE OF NATURAL AND SYNTHETIC PROTEIN FILAMENTS FROM STRIATED MUSCLE. J Mol Biol (1963) 7.08
Preparation of myosin and its subfragments from rabbit skeletal muscle. Methods Enzymol (1982) 6.29
Nonequilibrium mechanics of active cytoskeletal networks. Science (2007) 3.94
Nonmuscle myosin II moves in new directions. J Cell Sci (2008) 3.39
Actin stress fibres. J Cell Sci (2007) 3.28
A quantitative analysis of contractility in active cytoskeletal protein networks. Biophys J (2008) 2.05
Image averaging of flexible fibrous macromolecules: the clathrin triskelion has an elastic proximal segment. J Struct Biol (1991) 1.94
Polarity and velocity of sliding filaments: control of direction by actin and of speed by myosin. Science (1990) 1.76
Myosin filamentogenesis: effects of pH and ionic concentration. J Mol Biol (1966) 1.48
Vesicle transport: the role of actin filaments and myosin motors. Microsc Res Tech (1999) 1.46
New fluorescent tools for watching nanometer-scale conformational changes of single molecules. Annu Rev Biophys Biomol Struct (2007) 1.38
Assembly processes in vertebrate skeletal thick filament formation. Annu Rev Biophys Biophys Chem (1988) 1.28
Arrangement of myosin heads in relaxed thick filaments from frog skeletal muscle. J Mol Biol (1986) 1.28
Dynamic exchange of myosin molecules between thick filaments. Proc Natl Acad Sci U S A (1986) 1.26
Assembly dynamics of Mycobacterium tuberculosis FtsZ. J Biol Chem (2007) 1.22
Protein machines and self assembly in muscle organization. Bioessays (1999) 0.99
Movement of actin away from the center of reconstituted rabbit myosin filament is slower than in the opposite direction. Biophys J (1993) 0.94
Visualization of myosin exchange between synthetic thick filaments. J Muscle Res Cell Motil (1991) 0.93
Actin sliding on reconstituted myosin filaments containing only one myosin heavy chain isoform. J Muscle Res Cell Motil (2003) 0.91
Periodically arranged interactions within the myosin filament backbone revealed by mechanical unzipping. J Mol Biol (2008) 0.90
Myosin thick filaments and subunit exchange: a stochastic simulation based on the kinetics of assembly. Biochemistry (1993) 0.87
Location of SH1 and SH2 along a heavy chain of myosin subfragment 1. Biochemistry (1981) 0.86
Physical integrity of smooth muscle myosin filaments is enhanced by phosphorylation of the regulatory myosin light chain. Cell Physiol Biochem (2007) 0.85
The myosin filament. XII. Effect of MgATP on assembly. J Muscle Res Cell Motil (1986) 0.82
Myosin monomer density and exchange in synthetic thick filaments investigated using fluorescence microscopy with single molecule sensitivity. Proc Biol Sci (2000) 0.78
Matrix elasticity directs stem cell lineage specification. Cell (2006) 43.00
Myosin V walks hand-over-hand: single fluorophore imaging with 1.5-nm localization. Science (2003) 20.21
Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments. J Cell Biol (2004) 7.38
Shape effects of filaments versus spherical particles in flow and drug delivery. Nat Nanotechnol (2007) 6.85
Substrate compliance versus ligand density in cell on gel responses. Biophys J (2004) 6.71
Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation. Science (2013) 6.43
Three-dimensional structural dynamics of myosin V by single-molecule fluorescence polarization. Nature (2003) 4.52
Physical plasticity of the nucleus in stem cell differentiation. Proc Natl Acad Sci U S A (2007) 4.30
Differential regulation of dynein and kinesin motor proteins by tau. Science (2008) 4.29
Forced unfolding of proteins within cells. Science (2007) 3.95
Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating. J Cell Sci (2008) 3.86
Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance. Am J Physiol Heart Circ Physiol (2006) 3.78
Processive bidirectional motion of dynein-dynactin complexes in vitro. Nat Cell Biol (2006) 3.56
Orientation and rotational motions of single molecules by polarized total internal reflection fluorescence microscopy (polTIRFM). Cold Spring Harb Protoc (2012) 2.71
The nuclear envelope lamina network has elasticity and a compressibility limit suggestive of a molecular shock absorber. J Cell Sci (2004) 2.47
Minimal "Self" peptides that inhibit phagocytic clearance and enhance delivery of nanoparticles. Science (2013) 2.42
Inhibition of "self" engulfment through deactivation of myosin-II at the phagocytic synapse between human cells. J Cell Biol (2008) 2.39
Bio-inspired, bioengineered and biomimetic drug delivery carriers. Nat Rev Drug Discov (2011) 2.32
Multiscale mechanics of fibrin polymer: gel stretching with protein unfolding and loss of water. Science (2009) 2.30
Defocused orientation and position imaging (DOPI) of myosin V. Proc Natl Acad Sci U S A (2006) 2.27
Power-law rheology of isolated nuclei with deformation mapping of nuclear substructures. Biophys J (2005) 2.19
Microtubule plus-end tracking by CLIP-170 requires EB1. Proc Natl Acad Sci U S A (2009) 2.15
Polymer vesicles in vivo: correlations with PEG molecular weight. J Control Release (2003) 2.07
Self-assembly and properties of diblock copolymers by coarse-grain molecular dynamics. Nat Mater (2004) 2.07
MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments. J Cell Biol (2002) 2.04
Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival. J Cell Biol (2014) 2.01
Forced unfolding of coiled-coils in fibrinogen by single-molecule AFM. Biophys J (2006) 1.96
Cell responses to the mechanochemical microenvironment--implications for regenerative medicine and drug delivery. Adv Drug Deliv Rev (2007) 1.94
Force generation in single conventional actomyosin complexes under high dynamic load. Biophys J (2005) 1.90
Measurement of single macromolecule orientation by total internal reflection fluorescence polarization microscopy. Biophys J (2005) 1.88
Adhesively-tensed cell membranes: lysis kinetics and atomic force microscopy probing. Biophys J (2003) 1.77
Local cytoskeletal and organelle interactions impact molecular-motor- driven early endosomal trafficking. Curr Biol (2013) 1.76
Protein synthesis by single ribosomes. RNA (2003) 1.74
Microtissue elasticity: measurements by atomic force microscopy and its influence on cell differentiation. Methods Cell Biol (2007) 1.74
Matrix elasticity, cytoskeletal forces and physics of the nucleus: how deeply do cells 'feel' outside and in? J Cell Sci (2010) 1.73
Cooperativity in forced unfolding of tandem spectrin repeats. Biophys J (2003) 1.70
Kinesin and dynein-dynactin at intersecting microtubules: motor density affects dynein function. Biophys J (2008) 1.70
Biodegradable polymersomes loaded with both paclitaxel and doxorubicin permeate and shrink tumors, inducing apoptosis in proportion to accumulated drug. J Control Release (2006) 1.69
Preparation of filamentous actin for polarized total internal reflection fluorescence microscopy (polTIRFM) motility assays. Cold Spring Harb Protoc (2012) 1.69
Single-molecule fluorescence measurements of ribosomal translocation dynamics. Mol Cell (2011) 1.65
Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain. J Cell Biol (2012) 1.65
Species- and cell type-specific interactions between CD47 and human SIRPalpha. Blood (2005) 1.63
Rotational motions of macro-molecules by single-molecule fluorescence microscopy. Acc Chem Res (2005) 1.63
Shrinkage of a rapidly growing tumor by drug-loaded polymersomes: pH-triggered release through copolymer degradation. Mol Pharm (2006) 1.61
Indentation and adhesive probing of a cell membrane with AFM: theoretical model and experiments. Biophys J (2005) 1.56
The polarized total internal reflection fluorescence microscopy (polTIRFM) processive motility assay for myosin V. Cold Spring Harb Protoc (2012) 1.56
Self-porating polymersomes of PEG-PLA and PEG-PCL: hydrolysis-triggered controlled release vesicles. J Control Release (2004) 1.55
Myosin VI walks "wiggly" on actin with large and variable tilting. Mol Cell (2007) 1.54
The polarized total internal reflection fluorescence microscopy (polTIRFM) twirling filament assay. Cold Spring Harb Protoc (2012) 1.54
The acquisition and analysis of polarized total internal reflection fluorescence microscopy (polTIRFM) data. Cold Spring Harb Protoc (2012) 1.51
How deeply cells feel: methods for thin gels. J Phys Condens Matter (2010) 1.51
Unfolding a linker between helical repeats. J Mol Biol (2005) 1.48
Fluorescent labeling of myosin V for polarized total internal reflection fluorescence microscopy (polTIRFM) motility assays. Cold Spring Harb Protoc (2012) 1.48
Coordination of molecular motors: from in vitro assays to intracellular dynamics. Curr Opin Cell Biol (2010) 1.47
Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors. Proc Natl Acad Sci U S A (2012) 1.47
Kinetic characterization of the weak binding states of myosin V. Biochemistry (2002) 1.46
Pathway shifts and thermal softening in temperature-coupled forced unfolding of spectrin domains. Biophys J (2003) 1.46
Flexible filaments for in vivo imaging and delivery: persistent circulation of filomicelles opens the dosage window for sustained tumor shrinkage. Mol Pharm (2009) 1.45
Targeted worm micelles. Biomacromolecules (2004) 1.45
Orientation changes of the myosin light chain domain during filament sliding in active and rigor muscle. J Mol Biol (2002) 1.42
Myosin VI dimerization triggers an unfolding of a three-helix bundle in order to extend its reach. Mol Cell (2009) 1.42
Matrix elasticity, cytoskeletal tension, and TGF-beta: the insoluble and soluble meet. Sci Signal (2008) 1.42
Matrix strains induced by cells: Computing how far cells can feel. Cell Mol Bioeng (2009) 1.41
Adaptability of myosin V studied by simultaneous detection of position and orientation. EMBO J (2006) 1.40
Spotted vesicles, striped micelles and Janus assemblies induced by ligand binding. Nat Mater (2009) 1.40
Visualization of the dynamics of fibrin clot growth 1 molecule at a time by total internal reflection fluorescence microscopy. Blood (2012) 1.39
Micelles of different morphologies--advantages of worm-like filomicelles of PEO-PCL in paclitaxel delivery. Pharm Res (2007) 1.38
Cargo binding induces dimerization of myosin VI. Proc Natl Acad Sci U S A (2009) 1.34
Fluorescent labeling of calmodulin with bifunctional rhodamine. Cold Spring Harb Protoc (2012) 1.33
Conformational changes and signaling in cell and matrix physics. Curr Biol (2009) 1.33
Self inhibition of phagocytosis: the affinity of 'marker of self' CD47 for SIRPalpha dictates potency of inhibition but only at low expression levels. Blood Cells Mol Dis (2010) 1.31
Single-molecule stepping and structural dynamics of myosin X. Nat Struct Mol Biol (2010) 1.31
Motor number controls cargo switching at actin-microtubule intersections in vitro. Curr Biol (2010) 1.30
Hydrolytic degradation of poly(ethylene oxide)-block-polycaprolactone worm micelles. J Am Chem Soc (2005) 1.30
Elasticity of native and cross-linked polyelectrolyte multilayer films. Biomacromolecules (2004) 1.30
Patterning, prestress, and peeling dynamics of myocytes. Biophys J (2004) 1.29
Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes. Proc Natl Acad Sci U S A (2011) 1.28
Single-molecule structural dynamics of EF-G--ribosome interaction during translocation. Biochemistry (2007) 1.27
Construction of flow chambers for polarized total internal reflection fluorescence microscopy (polTIRFM) motility assays. Cold Spring Harb Protoc (2012) 1.25
Myosin Va and myosin VI coordinate their steps while engaged in an in vitro tug of war during cargo transport. Proc Natl Acad Sci U S A (2011) 1.23
Effect of inorganic phosphate on the force and number of myosin cross-bridges during the isometric contraction of permeabilized muscle fibers from rabbit psoas. Biophys J (2008) 1.23
Pathogenic proline mutation in the linker between spectrin repeats: disease caused by spectrin unfolding. Blood (2006) 1.22
Topographical pattern dynamics in passive adhesion of cell membranes. Biophys J (2004) 1.21
Polymersome carriers: from self-assembly to siRNA and protein therapeutics. Eur J Pharm Biopharm (2008) 1.21
Calcium-dependent lateral organization in phosphatidylinositol 4,5-bisphosphate (PIP2)- and cholesterol-containing monolayers. Biochemistry (2009) 1.21
Phylogenetic divergence of CD47 interactions with human signal regulatory protein alpha reveals locus of species specificity. Implications for the binding site. J Biol Chem (2006) 1.20
Adhesion-contractile balance in myocyte differentiation. J Cell Sci (2004) 1.20
Hyaluronic acid matrices show matrix stiffness in 2D and 3D dictates cytoskeletal order and myosin-II phosphorylation within stem cells. Integr Biol (Camb) (2012) 1.20
Allosteric vs. spontaneous exit-site (E-site) tRNA dissociation early in protein synthesis. Proc Natl Acad Sci U S A (2011) 1.18
Polymeric worm micelles as nano-carriers for drug delivery. Nanotechnology (2005) 1.17
The effect of CD47 modified polymer surfaces on inflammatory cell attachment and activation. Biomaterials (2011) 1.17
Mechanism of inhibition of skeletal muscle actomyosin by N-benzyl-p-toluenesulfonamide. Biochemistry (2003) 1.17
Heart-specific stiffening in early embryos parallels matrix and myosin expression to optimize beating. Curr Biol (2013) 1.17
Mechanical studies of single ribosome/mRNA complexes. Biophys J (2005) 1.16
Dynein tethers and stabilizes dynamic microtubule plus ends. Curr Biol (2012) 1.16
Orientation of the myosin light chain region by single molecule total internal reflection fluorescence polarization microscopy. Biophys J (2005) 1.15
Twirling of actin by myosins II and V observed via polarized TIRF in a modified gliding assay. Biophys J (2008) 1.15
Parallax: high accuracy three-dimensional single molecule tracking using split images. Nano Lett (2009) 1.13
Dynamics of translation by single ribosomes through mRNA secondary structures. Nat Struct Mol Biol (2013) 1.13
Electron tomography of cryofixed, isometrically contracting insect flight muscle reveals novel actin-myosin interactions. PLoS One (2010) 1.13