Published in J Biol Chem on February 28, 2005
Life cycle of connexins in health and disease. Biochem J (2006) 3.44
Zonula occludens-1 alters connexin43 gap junction size and organization by influencing channel accretion. Mol Biol Cell (2005) 2.62
Inhibition of gap junction communication at ectopic Eph/ephrin boundaries underlies craniofrontonasal syndrome. PLoS Biol (2006) 2.43
Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. J Clin Invest (2009) 1.98
Implications and challenges of connexin connections to cancer. Nat Rev Cancer (2010) 1.85
Molecular composition of the intercalated disc in a spontaneous canine animal model of arrhythmogenic right ventricular dysplasia/cardiomyopathy. Heart Rhythm (2007) 1.70
Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy. Mol Cell Biol (2007) 1.63
Electrophysiological mechanisms of antiarrhythmic protection during hypothermia in winter hibernating versus nonhibernating mammals. Heart Rhythm (2008) 1.56
Conduction remodeling in human end-stage nonischemic left ventricular cardiomyopathy. Circulation (2012) 1.53
Cx43 CT domain influences infarct size and susceptibility to ventricular tachyarrhythmias in acute myocardial infarction. Cardiovasc Res (2009) 1.51
Connexins: a myriad of functions extending beyond assembly of gap junction channels. Cell Commun Signal (2009) 1.49
Gap junctions in the control of vascular function. Antioxid Redox Signal (2009) 1.47
N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility. J Mol Cell Cardiol (2007) 1.30
The myoendothelial junction: breaking through the matrix? Microcirculation (2009) 1.30
Glial connexins and gap junctions in CNS inflammation and disease. J Neurochem (2008) 1.17
Adhesive properties of connexin hemichannels. Glia (2008) 1.14
Connexins and pannexins: Coordinating cellular communication in the testis and epididymis. Spermatogenesis (2011) 1.13
Connexin 43 regulates epicardial cell polarity and migration in coronary vascular development. Development (2009) 1.10
N-cadherin ligation, but not Sonic hedgehog binding, initiates Cdo-dependent p38alpha/beta MAPK signaling in skeletal myoblasts. Proc Natl Acad Sci U S A (2010) 1.07
The connexin43 carboxyl terminus and cardiac gap junction organization. Biochim Biophys Acta (2011) 1.05
Connexin43 modulates cell polarity and directional cell migration by regulating microtubule dynamics. PLoS One (2011) 1.05
Cell adhesion and its endocytic regulation in cell migration during neural development and cancer metastasis. Int J Mol Sci (2012) 1.04
Increased coherence of circadian rhythms in mature fibroblast cultures. J Biol Rhythms (2008) 1.03
Reduction and redistribution of gap and adherens junction proteins after ischemia and reperfusion. Ann Thorac Surg (2006) 1.02
Connexon-mediated cell adhesion drives microtissue self-assembly. FASEB J (2010) 1.01
Dysregulation of cell adhesion proteins and cardiac arrhythmogenesis. Clin Med Res (2006) 1.01
Mechanisms of gap junction traffic in health and disease. J Cardiovasc Pharmacol (2009) 1.00
Incidence of protein on actin bridges between endothelium and smooth muscle in arterioles demonstrates heterogeneous connexin expression and phosphorylation. Am J Physiol Heart Circ Physiol (2008) 0.95
In vitro cardiomyogenic potential of human amniotic fluid stem cells. J Tissue Eng Regen Med (2011) 0.95
Heteromerization of innexin gap junction proteins regulates epithelial tissue organization in Drosophila. Mol Biol Cell (2006) 0.93
Cx50 requires an intact PDZ-binding motif and ZO-1 for the formation of functional intercellular channels. Mol Biol Cell (2011) 0.93
Gap junctions and blood-tissue barriers. Adv Exp Med Biol (2012) 0.92
Reciprocal influence of connexins and apical junction proteins on their expressions and functions. Biochim Biophys Acta (2008) 0.91
Targeting Cx43 and N-cadherin, which are abnormally upregulated in venous leg ulcers, influences migration, adhesion and activation of Rho GTPases. PLoS One (2012) 0.90
Connexin 43 expression is associated with increased malignancy in prostate cancer cell lines and functions to promote migration. Oncotarget (2015) 0.89
HuR regulates gap junctional intercellular communication by controlling beta-catenin levels and adherens junction integrity. Hepatology (2009) 0.89
Xin proteins and intercalated disc maturation, signaling and diseases. Front Biosci (Landmark Ed) (2012) 0.88
Assembly of connexin43 into gap junctions is regulated differentially by E-cadherin and N-cadherin in rat liver epithelial cells. Mol Biol Cell (2010) 0.86
Intracellular Cleavage of the Cx43 C-Terminal Domain by Matrix-Metalloproteases: A Novel Contributor to Inflammation? Mediators Inflamm (2015) 0.85
Cell-cell junction remodeling in the heart: possible role in cardiac conduction system function and arrhythmias? Life Sci (2011) 0.85
Angiomotin is a novel component of cadherin-11/β-catenin/p120 complex and is critical for cadherin-11-mediated cell migration. FASEB J (2014) 0.83
Cross-talk between tight and anchoring junctions-lesson from the testis. Adv Exp Med Biol (2008) 0.83
Adaptive calcified matrix response of dental pulp to bacterial invasion is associated with establishment of a network of glial fibrillary acidic protein+/glutamine synthetase+ cells. Am J Pathol (2010) 0.82
Stat3 is a positive regulator of gap junctional intercellular communication in cultured, human lung carcinoma cells. BMC Cancer (2012) 0.81
Stat3 and gap junctions in normal and lung cancer cells. Cancers (Basel) (2014) 0.78
Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression. Carcinogenesis (2015) 0.77
Thermo-responsive methylcellulose hydrogels as temporary substrate for cell sheet biofabrication. J Mater Sci Mater Med (2016) 0.77
Inhibition of histone deacetylase (HDAC) by 4-phenylbutyrate results in increased junctional conductance between rat corpora smooth muscle cells. Front Pharmacol (2015) 0.77
Involvement of Rictor/mTORC2 in cardiomyocyte differentiation of mouse embryonic stem cells in vitro. Int J Biol Sci (2017) 0.77
Neuronal cadherin (NCAD) increases sensory neurite formation and outgrowth on astrocytes. Neurosci Lett (2012) 0.76
The role of the C-terminus in functional expression and internalization of rat connexin46 (rCx46). J Bioenerg Biomembr (2012) 0.76
Changes in endothelial connexin 43 expression inversely correlate with microvessel permeability and VE-cadherin expression in endotoxin-challenged lungs. Am J Physiol Lung Cell Mol Physiol (2015) 0.76
Novel methods of automated quantification of gap junction distribution and interstitial collagen quantity from animal and human atrial tissue sections. PLoS One (2014) 0.75
The assembly of developing motor neurons depends on an interplay between spontaneous activity, type II cadherins and gap junctions. Development (2017) 0.75
Microdomain-specific localization of functional ion channels in cardiomyocytes: an emerging concept of local regulation and remodelling. Biophys Rev (2015) 0.75
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics. Genet Epidemiol (2004) 5.57
RePS: a sequence assembler that masks exact repeats identified from the shotgun data. Genome Res (2002) 4.35
A multivariate family-based association test using generalized estimating equations: FBAT-GEE. Biostatistics (2003) 3.52
Th1-Th17 cells mediate protective adaptive immunity against Staphylococcus aureus and Candida albicans infection in mice. PLoS Pathog (2009) 3.05
DAPK1 interaction with NMDA receptor NR2B subunits mediates brain damage in stroke. Cell (2010) 2.87
A common haplotype of the nicotine acetylcholine receptor alpha 4 subunit gene is associated with vulnerability to nicotine addiction in men. Am J Hum Genet (2004) 2.47
Endothelial cell recovery between comparator polymer-based drug-eluting stents. J Am Coll Cardiol (2008) 2.45
Pathway pathology: histological differences between ErbB/Ras and Wnt pathway transgenic mammary tumors. Am J Pathol (2002) 2.26
Klf2 is an essential regulator of vascular hemodynamic forces in vivo. Dev Cell (2006) 2.26
Connexins and cell signaling in development and disease. Annu Rev Cell Dev Biol (2004) 2.25
Extracellular superoxide dismutase deficiency exacerbates pressure overload-induced left ventricular hypertrophy and dysfunction. Hypertension (2007) 2.20
Upregulation of arginase by H2O2 impairs endothelium-dependent nitric oxide-mediated dilation of coronary arterioles. Arterioscler Thromb Vasc Biol (2006) 2.12
An MRI-based atlas and database of the developing mouse brain. Neuroimage (2010) 1.99
Disposition of caspofungin: role of distribution in determining pharmacokinetics in plasma. Antimicrob Agents Chemother (2004) 1.86
Peroxisome proliferator-activated receptor alpha agonists increase nitric oxide synthase expression in vascular endothelial cells. Arterioscler Thromb Vasc Biol (2004) 1.83
The Golgin GMAP210/TRIP11 anchors IFT20 to the Golgi complex. PLoS Genet (2008) 1.80
Synovial fibroblasts promote osteoclast formation by RANKL in a novel model of spontaneous erosive arthritis. Arthritis Rheum (2005) 1.79
miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis. Nat Cell Biol (2013) 1.79
Rapid high resolution three dimensional reconstruction of embryos with episcopic fluorescence image capture. Birth Defects Res C Embryo Today (2004) 1.74
Increased postoperative and respiratory complications in patients with congenital heart disease associated with heterotaxy. J Thorac Cardiovasc Surg (2010) 1.74
Inducible nitric oxide synthase deficiency protects the heart from systolic overload-induced ventricular hypertrophy and congestive heart failure. Circ Res (2007) 1.73
Downregulation of adipose glutathione S-transferase A4 leads to increased protein carbonylation, oxidative stress, and mitochondrial dysfunction. Diabetes (2010) 1.70
The effects of light on bleaching and tooth sensitivity during in-office vital bleaching: a systematic review and meta-analysis. J Dent (2012) 1.67
Effects of age at menarche, reproductive years, and menopause on metabolic risk factors for cardiovascular diseases. Atherosclerosis (2007) 1.67
Outflow tract cushions perform a critical valve-like function in the early embryonic heart requiring BMPRIA-mediated signaling in cardiac neural crest. Am J Physiol Heart Circ Physiol (2009) 1.66
IL-13 blockade reduces lung inflammation after Ascaris suum challenge in cynomolgus monkeys. J Allergy Clin Immunol (2007) 1.63
Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signaling. PLoS One (2008) 1.63
Stent graft-induced new entry after endovascular repair for Stanford type B aortic dissection. J Vasc Surg (2010) 1.62
ENU induced mutations causing congenital cardiovascular anomalies. Development (2004) 1.58
Anesthesia with nontracheal intubation in thoracic surgery. J Thorac Dis (2012) 1.56
Oxidative stress regulates left ventricular PDE5 expression in the failing heart. Circulation (2010) 1.54
AMP activated protein kinase-alpha2 deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction in mice. Hypertension (2008) 1.54
Kinase-inactive glycogen synthase kinase 3beta promotes Wnt signaling and mammary tumorigenesis. Cancer Res (2005) 1.50
Heterotaxy and complex structural heart defects in a mutant mouse model of primary ciliary dyskinesia. J Clin Invest (2007) 1.49
Eya1 is required for the morphogenesis of mammalian thymus, parathyroid and thyroid. Development (2002) 1.49
PGC-1 alpha regulates expression of myocardial mitochondrial antioxidants and myocardial oxidative stress after chronic systolic overload. Antioxid Redox Signal (2010) 1.48
Disposition of caspofungin, a novel antifungal agent, in mice, rats, rabbits, and monkeys. Antimicrob Agents Chemother (2004) 1.48
High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy. Circulation (2012) 1.44
Doubly hybrid density functional xDH-PBE0 from a parameter-free global hybrid model PBE0. J Chem Phys (2012) 1.44
DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat Genet (2013) 1.44
Activation of different Wnt/beta-catenin signaling components in mammary epithelium induces transdifferentiation and the formation of pilar tumors. Oncogene (2002) 1.43
A potential probe set of fluorescence in situ hybridization for detection of lung cancer in bronchial brushing specimens. J Cancer Res Clin Oncol (2012) 1.43
A longitudinal assessment of coronary interventional program quality: a report from the American College of Cardiology-National Cardiovascular Data Registry. JACC Cardiovasc Interv (2009) 1.41
IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport. Dev Cell (2012) 1.40
Long-term outcome of hybrid surgical approach of video-assisted minithoracotomy sleeve lobectomy for non-small-cell lung cancer. Surg Endosc (2011) 1.40
Long-term outcome and cost-effectiveness of complete versus assisted video-assisted thoracic surgery for non-small cell lung cancer. J Surg Oncol (2011) 1.40
Origins of phase contrast in the atomic force microscope in liquids. Proc Natl Acad Sci U S A (2009) 1.38
Functional genomic screens identify CINP as a genome maintenance protein. Proc Natl Acad Sci U S A (2009) 1.38
A new multimarker test for family-based association studies. Genet Epidemiol (2007) 1.34
Retrograde type A aortic dissection after endovascular stent graft placement for treatment of type B dissection. Circulation (2009) 1.33
Role of the urate transporter SLC2A9 gene in susceptibility to gout in New Zealand Māori, Pacific Island, and Caucasian case-control sample sets. Arthritis Rheum (2009) 1.32
Power estimation of multiple SNP association test of case-control study and application. Genet Epidemiol (2004) 1.31
Differential regulation of membrane guanylyl cyclases in congestive heart failure: natriuretic peptide receptor (NPR)-B, Not NPR-A, is the predominant natriuretic peptide receptor in the failing heart. Endocrinology (2007) 1.31
Variation in genes involved in the RANKL/RANK/OPG bone remodeling pathway are associated with bone mineral density at different skeletal sites in men. Hum Genet (2005) 1.30
Amplification and overexpression of CTTN (EMS1) contribute to the metastasis of esophageal squamous cell carcinoma by promoting cell migration and anoikis resistance. Cancer Res (2006) 1.29
Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development. Dev Biol (2008) 1.29
Extracellular superoxide dismutase protects the heart against oxidative stress and hypertrophy after myocardial infarction. Free Radic Biol Med (2007) 1.29
Problems with the microbial production of butanol. J Ind Microbiol Biotechnol (2009) 1.28
Targeting Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) with small molecule inhibitors for the treatment of metabolic diseases. J Biol Chem (2011) 1.28
Cyclin-dependent kinase 2 dependent phosphorylation of ATRIP regulates the G2-M checkpoint response to DNA damage. Cancer Res (2007) 1.27
Connexin 43-mediated modulation of polarized cell movement and the directional migration of cardiac neural crest cells. Development (2006) 1.27
EPAC null mutation impairs learning and social interactions via aberrant regulation of miR-124 and Zif268 translation. Neuron (2012) 1.27
Elevated expression of p63 protein in human esophageal squamous cell carcinomas. Int J Cancer (2002) 1.26
New alkali doped pillared carbon materials designed to achieve practical reversible hydrogen storage for transportation. Phys Rev Lett (2004) 1.25
Prevalence of metabolic syndrome and its relation to body composition in a Chinese rural population. Obesity (Silver Spring) (2006) 1.24
Adenosine A3 receptor deficiency exerts unanticipated protective effects on the pressure-overloaded left ventricle. Circulation (2008) 1.24
Predominance of nontypeable Haemophilus influenzae in children with otitis media following introduction of a 3+0 pneumococcal conjugate vaccine schedule. Vaccine (2011) 1.24
Overexpression of PLK1 is associated with poor survival by inhibiting apoptosis via enhancement of survivin level in esophageal squamous cell carcinoma. Int J Cancer (2009) 1.23
Mechanism for antibody catalysis of the oxidation of water by singlet dioxygen. Proc Natl Acad Sci U S A (2002) 1.23
A candidate gene association study on preterm delivery: application of high-throughput genotyping technology and advanced statistical methods. Hum Mol Genet (2004) 1.23
In situ growth of Co(0.85)Se and Ni(0.85)Se on conductive substrates as high-performance counter electrodes for dye-sensitized solar cells. J Am Chem Soc (2012) 1.22
Treatment of symptomatic isolated dissection of superior mesenteric artery. J Vasc Surg (2013) 1.22
Amplification of PRKCI, located in 3q26, is associated with lymph node metastasis in esophageal squamous cell carcinoma. Genes Chromosomes Cancer (2008) 1.20
Collaborative development of 2-hydroxypropyl-β-cyclodextrin for the treatment of Niemann-Pick type C1 disease. Curr Top Med Chem (2014) 1.19
Massively parallel sequencing identifies the gene Megf8 with ENU-induced mutation causing heterotaxy. Proc Natl Acad Sci U S A (2009) 1.19
Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine. Arterioscler Thromb Vasc Biol (2011) 1.19
USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase. J Exp Med (2014) 1.18
Disruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndrome. Dis Model Mech (2010) 1.18
ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry. Am J Hum Genet (2013) 1.17
Spermatogenesis of mice lacking CK2alpha': failure of germ cell survival and characteristic modifications of the spermatid nucleus. Mol Reprod Dev (2003) 1.17
Revealing the molecular structure of single-molecule junctions in different conductance states by fishing-mode tip-enhanced Raman spectroscopy. Nat Commun (2011) 1.17
Dimethylarginine dimethylaminohydrolase and endothelial dysfunction in failing hearts. Am J Physiol Heart Circ Physiol (2005) 1.16
Age-related increase of tumor susceptibility is associated with myeloid-derived suppressor cell mediated suppression of T cell cytotoxicity in recombinant inbred BXD12 mice. Mech Ageing Dev (2007) 1.14
Feasibility of complete video-assisted thoracoscopic surgery following neoadjuvant therapy for locally advanced non-small cell lung cancer. J Thorac Dis (2013) 1.13
Renal hyporesponsiveness to atrial natriuretic peptide in congestive heart failure results from reduced atrial natriuretic peptide receptor concentrations. Am J Physiol Renal Physiol (2007) 1.13
High-frequency ultrasound database profiling growth, development, and cardiovascular function in C57BL/6J mouse fetuses. J Am Soc Echocardiogr (2004) 1.13
miR-26a inhibits proliferation and motility in bladder cancer by targeting HMGA1. FEBS Lett (2013) 1.12
Visual saliency based on scale-space analysis in the frequency domain. IEEE Trans Pattern Anal Mach Intell (2013) 1.12
MicroRNA-124-3p inhibits cell migration and invasion in bladder cancer cells by targeting ROCK1. J Transl Med (2013) 1.11
Optimization of fatty alcohol biosynthesis pathway for selectively enhanced production of C12/14 and C16/18 fatty alcohols in engineered Escherichia coli. Microb Cell Fact (2012) 1.11
Three isoforms of annexin I are preferentially expressed in normal esophageal epithelia but down-regulated in esophageal squamous cell carcinomas. Oncogene (2002) 1.11
Connexin 43 regulates epicardial cell polarity and migration in coronary vascular development. Development (2009) 1.10