Published in Mol Endocrinol on October 11, 2007
The biology of activin: recent advances in structure, regulation and function. J Endocrinol (2009) 1.64
Accelerated ovarian aging in the absence of the transcription regulator TAF4B in mice. Biol Reprod (2009) 1.18
Follistatin improves skeletal muscle healing after injury and disease through an interaction with muscle regeneration, angiogenesis, and fibrosis. Am J Pathol (2011) 1.07
Inhibin at 90: from discovery to clinical application, a historical review. Endocr Rev (2014) 0.91
The follistatin-288 isoform alone is sufficient for survival but not for normal fertility in mice. Endocrinology (2009) 0.90
Maternal protein restriction induces early-onset glucose intolerance and alters hepatic genes expression in the peroxisome proliferator-activated receptor pathway in offspring. J Diabetes Investig (2014) 0.82
Cell-type specific modulation of pituitary cells by activin, inhibin and follistatin. Mol Cell Endocrinol (2012) 0.81
Keratinocyte-derived follistatin regulates epidermal homeostasis and wound repair. Lab Invest (2008) 0.81
The Local Control of the Pituitary by Activin Signaling and Modulation. Open Neuroendocrinol J (2011) 0.77
The effects of transforming growth factor-β2 on the expression of follistatin and activin A in normal and glaucomatous human trabecular meshwork cells and tissues. Invest Ophthalmol Vis Sci (2012) 0.76
Follistatin is critical for mouse uterine receptivity and decidualization. Proc Natl Acad Sci U S A (2017) 0.75
Clinical and Therapeutic Implications of Follistatin in Solid Tumours. Cancer Genomics Proteomics (2016) 0.75
Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes Dev (1995) 7.16
Regulation of myostatin activity and muscle growth. Proc Natl Acad Sci U S A (2001) 6.38
Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment. Mamm Genome (1997) 4.15
Determination of the estrous cycle phases of rats: some helpful considerations. Braz J Biol (2003) 3.88
Genetic analysis of the mammalian transforming growth factor-beta superfamily. Endocr Rev (2002) 3.06
Multiple defects and perinatal death in mice deficient in follistatin. Nature (1995) 2.96
Activin-binding protein from rat ovary is follistatin. Science (1990) 2.38
Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis. Dev Dyn (2004) 1.96
Activins, inhibins, and follistatins: from endocrinology to signaling. A paradigm for the new millennium. Exp Biol Med (Maywood) (2002) 1.67
Granulosa cell-specific inactivation of follistatin causes female fertility defects. Mol Endocrinol (2003) 1.62
Molecular heterogeneity of follistatin, an activin-binding protein. Higher affinity of the carboxyl-terminal truncated forms for heparan sulfate proteoglycans on the ovarian granulosa cell. J Biol Chem (1993) 1.44
Bone morphogenetic protein (BMP) ligands and receptors in bovine ovarian follicle cells: actions of BMP-4, -6 and -7 on granulosa cells and differential modulation of Smad-1 phosphorylation by follistatin. Reproduction (2004) 1.30
Isolation and partial characterization of follistatin: a single-chain Mr 35,000 monomeric protein that inhibits the release of follicle-stimulating hormone. Proc Natl Acad Sci U S A (1987) 1.29
Progesterone via its receptor antagonizes the pro-inflammatory activity of estrogen in the mouse uterus. Biol Reprod (1999) 1.26
Endometrial expression and secretion of activin A, but not follistatin, increase in the secretory phase of the menstrual cycle. J Soc Gynecol Investig (2003) 1.12
The isolation of polypeptides with FSH suppressing activity from bovine follicular fluid which are structurally different to inhibin. Biochem Biophys Res Commun (1987) 1.12
Differential distribution of follistatin isoforms: application of a new FS315-specific immunoassay. J Clin Endocrinol Metab (2004) 1.12
Dissociation of angiogenesis and tumorigenesis in follistatin- and activin-expressing tumors. Cancer Res (2006) 1.10
Inhibition of vascular endothelial cell growth by activin-A. J Biol Chem (1993) 1.09
Activation and distribution of inflammatory cells in the mouse uterus during the preimplantation period. J Immunol (1992) 1.08
Immediate onset of DNA synthesis in remnant rat liver after 90% hepatectomy by an administration of follistatin. J Hepatol (1998) 1.04
Recruitment and development of the follicle; the roles of the transforming growth factor-beta superfamily. Mol Cell Endocrinol (2002) 1.04
The activin-binding protein follistatin regulates autocrine endothelial cell activity and induces angiogenesis. Lab Invest (1997) 1.03
The N-myc oncogene in human neuroblastoma cells: down-regulation of an angiogenesis inhibitor identified as activin A. Cancer Res (2000) 1.02
Activins as regulators of branching morphogenesis. Dev Biol (2001) 1.02
Influence of oestrogen and progesterone on macrophage distribution in the mouse uterus. J Endocrinol (1990) 1.02
Characterisation of the rapid release of activin A following acute lipopolysaccharide challenge in the ewe. J Endocrinol (2004) 1.01
Activin A suppresses neuroblastoma xenograft tumor growth via antimitotic and antiangiogenic mechanisms. Cancer Res (2005) 0.99
Semen activates the female immune response during early pregnancy in mice. Immunology (2004) 0.98
A single intraportal administration of follistatin accelerates liver regeneration in partially hepatectomized rats. Gastroenterology (1995) 0.97
Regulation of prostate branching morphogenesis by activin A and follistatin. Dev Biol (2001) 0.97
Role of high molecular weight seminal vesicle proteins in eliciting the uterine inflammatory response to semen in mice. J Reprod Fertil (1996) 0.95
Differential binding and neutralization of activins A and B by follistatin and follistatin like-3 (FSTL-3/FSRP/FLRG). Endocrinology (2003) 0.95
Follistatin is a candidate endogenous negative regulator of activin A in experimental allergic asthma. Clin Exp Allergy (2006) 0.93
Expression of activin receptors, follistatin and betaglycan by human endometrial stromal cells; consistent with a role for activins during decidualization. Mol Hum Reprod (2002) 0.93
Identification of a novel testis-specific member of the phosphatidylethanolamine binding protein family, pebp-2. Biol Reprod (2002) 0.93
High activin A-expression in human neuroblastoma: suppression of malignant potential and correlation with favourable clinical outcome. Oncogene (2005) 0.91
The role of activin and transforming growth factor-beta in the regulation of organ mass in the rat liver. Hepatology (2000) 0.89
Localization of follistatin in the rat testis. J Reprod Fertil (1998) 0.89
Activin a in the regulation of corneal neovascularization and vascular endothelial growth factor expression. Am J Pathol (2004) 0.86
Crucial role of activin a in tubulogenesis of endothelial cells induced by vascular endothelial growth factor. Endocrinology (2004) 0.85
Porcine follistatin gene structure supports two forms of mature follistatin produced by alternative splicing. Biochem Biophys Res Commun (1988) 0.85
Dynamics of inhibin subunit and follistatin mRNA during development of normal and polycystic ovary syndrome follicles. J Clin Endocrinol Metab (2001) 0.84
Stimulatory effects of lipopolysaccharide on endothelial cell activin and follistatin. Mol Cell Endocrinol (2006) 0.83
The activin binding proteins follistatin and follistatin-related protein are differentially regulated in vitro and during cutaneous wound repair. J Endocrinol (2001) 0.81
Ovarian regulation of endometrial gland morphogenesis and activin-follistatin system in the neonatal ovine uterus. Biol Reprod (2003) 0.80
Activin A as a critical mediator of capillary formation: interaction with the fibroblast growth factor action. Endocr J (2007) 0.78
Genetic analysis of the mammalian transforming growth factor-beta superfamily. Endocr Rev (2002) 3.06
Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice. Proc Natl Acad Sci U S A (2005) 2.84
NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression. Science (2004) 2.77
Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis. Proc Natl Acad Sci U S A (2005) 2.56
The mammalian ovary from genesis to revelation. Endocr Rev (2009) 2.31
Men in Australia Telephone Survey (MATeS): a national survey of the reproductive health and concerns of middle-aged and older Australian men. Lancet (2005) 2.25
Molecular profiling uncovers a p53-associated role for microRNA-31 in inhibiting the proliferation of serous ovarian carcinomas and other cancers. Cancer Res (2010) 2.16
A bioinformatics tool for linking gene expression profiling results with public databases of microRNA target predictions. RNA (2008) 2.16
Zygote arrest 1 (Zar1) is a novel maternal-effect gene critical for the oocyte-to-embryo transition. Nat Genet (2003) 2.09
GDF11 controls the timing of progenitor cell competence in developing retina. Science (2005) 2.04
Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal. Proc Natl Acad Sci U S A (2005) 2.04
High-grade serous ovarian cancer arises from fallopian tube in a mouse model. Proc Natl Acad Sci U S A (2012) 2.03
TEX14 is essential for intercellular bridges and fertility in male mice. Proc Natl Acad Sci U S A (2006) 2.01
Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis. Dev Dyn (2004) 1.96
A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer. Mol Endocrinol (2010) 1.94
Deletion of Dicer in somatic cells of the female reproductive tract causes sterility. Mol Endocrinol (2008) 1.91
Oogenesis requires germ cell-specific transcriptional regulators Sohlh1 and Lhx8. Proc Natl Acad Sci U S A (2006) 1.87
GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet (2009) 1.83
Regulation of muscle mass by follistatin and activins. Mol Endocrinol (2010) 1.79
Roles of NPM2 in chromatin and nucleolar organization in oocytes and embryos. Science (2003) 1.78
Knockout of pentraxin 3, a downstream target of growth differentiation factor-9, causes female subfertility. Mol Endocrinol (2002) 1.77
Targeted disruption of luteinizing hormone beta-subunit leads to hypogonadism, defects in gonadal steroidogenesis, and infertility. Proc Natl Acad Sci U S A (2004) 1.73
Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice. Mol Cell Biol (2007) 1.72
Absence of the DNA-/RNA-binding protein MSY2 results in male and female infertility. Proc Natl Acad Sci U S A (2005) 1.71
Oocyte regulation of metabolic cooperativity between mouse cumulus cells and oocytes: BMP15 and GDF9 control cholesterol biosynthesis in cumulus cells. Development (2007) 1.70
BMPR2 is required for postimplantation uterine function and pregnancy maintenance. J Clin Invest (2013) 1.70
Functional insights from the distribution and role of homopeptide repeat-containing proteins. Genome Res (2005) 1.70
MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing. PLoS Biol (2010) 1.68
Stable expression and characterization of N-terminal tagged recombinant human bone morphogenetic protein 15. Mol Hum Reprod (2009) 1.67
Mouse let-7 miRNA populations exhibit RNA editing that is constrained in the 5'-seed/ cleavage/anchor regions and stabilize predicted mmu-let-7a:mRNA duplexes. Genome Res (2008) 1.66
Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation. Dev Cell (2004) 1.65
Granulosa cell-specific inactivation of follistatin causes female fertility defects. Mol Endocrinol (2003) 1.62
Activin A is a critical component of the inflammatory response, and its binding protein, follistatin, reduces mortality in endotoxemia. Proc Natl Acad Sci U S A (2007) 1.62
Synergistic roles of BMP15 and GDF9 in the development and function of the oocyte-cumulus cell complex in mice: genetic evidence for an oocyte-granulosa cell regulatory loop. Dev Biol (2004) 1.58
Men in Australia Telephone Survey (MATeS): predictors of men's help-seeking behaviour for reproductive health disorders. Med J Aust (2006) 1.55
Nobox is a homeobox-encoding gene preferentially expressed in primordial and growing oocytes. Mech Dev (2002) 1.52
Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells. Development (2007) 1.50
Evidence that androgens regulate early developmental events, prior to sexual differentiation. Endocrinology (2007) 1.49
Growth differentiation factor 9:bone morphogenetic protein 15 heterodimers are potent regulators of ovarian functions. Proc Natl Acad Sci U S A (2013) 1.42
The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo. Development (2006) 1.40
As the world grows: contraception in the 21st century. J Clin Invest (2008) 1.37
Functional microRNA involved in endometriosis. Mol Endocrinol (2011) 1.36
Thyroid hormone, retinoic acid, and testosterone suppress proliferation and induce markers of differentiation in cultured rat sertoli cells. Endocrinology (2003) 1.36
Conversion of midbodies into germ cell intercellular bridges. Dev Biol (2007) 1.36
MRG15 regulates embryonic development and cell proliferation. Mol Cell Biol (2005) 1.35
Premature luteinization and cumulus cell defects in ovarian-specific Smad4 knockout mice. Mol Endocrinol (2006) 1.33
Loss of zona pellucida binding proteins in the acrosomal matrix disrupts acrosome biogenesis and sperm morphogenesis. Mol Cell Biol (2007) 1.31
HILS1 is a spermatid-specific linker histone H1-like protein implicated in chromatin remodeling during mammalian spermiogenesis. Proc Natl Acad Sci U S A (2003) 1.28
Major chromatin remodeling in the germinal vesicle (GV) of mammalian oocytes is dispensable for global transcriptional silencing but required for centromeric heterochromatin function. Dev Biol (2004) 1.28
Identification of Gasz, an evolutionarily conserved gene expressed exclusively in germ cells and encoding a protein with four ankyrin repeats, a sterile-alpha motif, and a basic leucine zipper. Mol Endocrinol (2002) 1.27
Intraovarian activins are required for female fertility. Mol Endocrinol (2007) 1.26
Discovery of novel microRNAs in female reproductive tract using next generation sequencing. PLoS One (2010) 1.26
Altered excitation-contraction coupling with skeletal muscle specific FKBP12 deficiency. FASEB J (2004) 1.24
Haploinsufficiency of kelch-like protein homolog 10 causes infertility in male mice. Proc Natl Acad Sci U S A (2004) 1.24
Activin and related proteins in inflammation: not just interested bystanders. Cytokine Growth Factor Rev (2009) 1.23
Non-invasive genetic diagnosis of male infertility using spermatozoal RNA: KLHL10 mutations in oligozoospermic patients impair homodimerization. Hum Mol Genet (2006) 1.23
Regulation of ovarian function by the TGF-beta superfamily and follistatin. Reproduction (2003) 1.23
Transforming growth factor β receptor type 1 is essential for female reproductive tract integrity and function. PLoS Genet (2011) 1.20
A mutation in the inner mitochondrial membrane peptidase 2-like gene (Immp2l) affects mitochondrial function and impairs fertility in mice. Biol Reprod (2007) 1.20
Fat aussie--a new Alström syndrome mouse showing a critical role for ALMS1 in obesity, diabetes, and spermatogenesis. Mol Endocrinol (2006) 1.18
The ubiquitin ligase component Siah1a is required for completion of meiosis I in male mice. Mol Cell Biol (2002) 1.18
Role of satellite cells versus myofibers in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway. Proc Natl Acad Sci U S A (2012) 1.18
Obox, a family of homeobox genes preferentially expressed in germ cells. Genomics (2002) 1.18
Granulosa cell-expressed BMPR1A and BMPR1B have unique functions in regulating fertility but act redundantly to suppress ovarian tumor development. Mol Endocrinol (2010) 1.17
Control of pelage hair follicle development and cycling by complex interactions between follistatin and activin. FASEB J (2003) 1.17
Follistatin attenuates early liver fibrosis: effects on hepatic stellate cell activation and hepatocyte apoptosis. Am J Physiol Gastrointest Liver Physiol (2005) 1.16
Redundant roles of SMAD2 and SMAD3 in ovarian granulosa cells in vivo. Mol Cell Biol (2008) 1.16
Germ cell intercellular bridges. Cold Spring Harb Perspect Biol (2011) 1.15
Effects of testosterone plus medroxyprogesterone acetate on semen quality, reproductive hormones, and germ cell populations in normal young men. J Clin Endocrinol Metab (2002) 1.15
RFPL4 interacts with oocyte proteins of the ubiquitin-proteasome degradation pathway. Proc Natl Acad Sci U S A (2003) 1.14
Bidirectional communication between oocytes and ovarian follicular somatic cells is required for meiotic arrest of mammalian oocytes. Proc Natl Acad Sci U S A (2013) 1.14
Sox8 is a critical regulator of adult Sertoli cell function and male fertility. Dev Biol (2008) 1.13
Previously uncharacterized roles of platelet-activating factor acetylhydrolase 1b complex in mouse spermatogenesis. Proc Natl Acad Sci U S A (2003) 1.13
Growth differentiation factor 9 regulates expression of the bone morphogenetic protein antagonist gremlin. J Biol Chem (2004) 1.12
Activin A and follistatin in systemic inflammation. Mol Cell Endocrinol (2004) 1.12
Minireview: genetic models for the study of gonadotropin actions. Endocrinology (2002) 1.12
Deficiency of growth differentiation factor 3 protects against diet-induced obesity by selectively acting on white adipose. Mol Endocrinol (2008) 1.11
Mouse TEX14 is required for embryonic germ cell intercellular bridges but not female fertility. Biol Reprod (2008) 1.11
TEX14 interacts with CEP55 to block cell abscission. Mol Cell Biol (2010) 1.10
Activin and GDF11 collaborate in feedback control of neuroepithelial stem cell proliferation and fate. Development (2011) 1.09
Analysis of microRNA expression in the prepubertal testis. PLoS One (2010) 1.08
Absence of tektin 4 causes asthenozoospermia and subfertility in male mice. FASEB J (2007) 1.08
The regulation and functions of activin and follistatin in inflammation and immunity. Vitam Horm (2011) 1.08
Inhibin, activin, follistatin and FSH serum levels and testicular production are highly modulated during the first spermatogenic wave in mice. Reproduction (2008) 1.07
A mouse model of spinal and bulbar muscular atrophy. Hum Mol Genet (2002) 1.06
Tektin3 encodes an evolutionarily conserved putative testicular microtubules-related protein expressed preferentially in male germ cells. Mol Reprod Dev (2004) 1.06
SMAD3 regulates gonadal tumorigenesis. Mol Endocrinol (2007) 1.05
High-throughput discovery of germ-cell-specific genes. Semin Reprod Med (2005) 1.05
FGFR-1 [corrected] signaling is involved in spermiogenesis and sperm capacitation. J Cell Sci (2005) 1.05
Sequence and expression of testis-expressed gene 14 (Tex14): a gene encoding a protein kinase preferentially expressed during spermatogenesis. Gene Expr Patterns (2003) 1.04
The testis-enriched histone demethylase, KDM4D, regulates methylation of histone H3 lysine 9 during spermatogenesis in the mouse but is dispensable for fertility. Biol Reprod (2011) 1.04
Mice deficient in oocyte-specific oligoadenylate synthetase-like protein OAS1D display reduced fertility. Mol Cell Biol (2005) 1.04
Deconstructing mammalian reproduction: using knockouts to define fertility pathways. Reproduction (2006) 1.02
The art and artifact of GDF9 activity: cumulus expansion and the cumulus expansion-enabling factor. Biol Reprod (2005) 1.02