PubRank

Bruce J Aronow

Author PubWeight™ 237.41‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Design and implementation of microarray gene expression markup language (MAGE-ML). Genome Biol 2002 16.75
2 ToppGene Suite for gene list enrichment analysis and candidate gene prioritization. Nucleic Acids Res 2009 7.34
3 Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. J Clin Invest 2006 5.48
4 Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling. Circ Res 2007 4.53
5 An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets. Genome Biol 2003 4.49
6 Cardiac-specific deletion of Gata4 reveals its requirement for hypertrophy, compensation, and myocyte viability. Circ Res 2006 4.41
7 ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo. Neuron 2004 4.21
8 Blockade of chronic type I interferon signaling to control persistent LCMV infection. Science 2013 4.14
9 Pattern of sequence variation across 213 environmental response genes. Genome Res 2004 3.93
10 The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor. Cell 2012 3.91
11 Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome. Physiol Genomics 2007 3.37
12 Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers. EMBO J 2004 3.32
13 Disease candidate gene identification and prioritization using protein interaction networks. BMC Bioinformatics 2009 3.03
14 Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. Genome Biol 2007 2.70
15 Detection and visualization of compositionally similar cis-regulatory element clusters in orthologous and coordinately controlled genes. Genome Res 2002 2.60
16 Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 2002 2.58
17 Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septic shock. Mol Med 2007 2.58
18 Improved human disease candidate gene prioritization using mouse phenotype. BMC Bioinformatics 2007 2.56
19 GUDMAP: the genitourinary developmental molecular anatomy project. J Am Soc Nephrol 2008 2.45
20 Atlas of gene expression in the developing kidney at microanatomic resolution. Dev Cell 2008 2.44
21 Genetic induction of proinflammatory immunity in children with biliary atresia. Lancet 2002 2.44
22 The GUDMAP database--an online resource for genitourinary research. Development 2011 2.20
23 Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays. Mol Cell Biol 2004 2.19
24 The retinoblastoma tumor suppressor modifies the therapeutic response of breast cancer. J Clin Invest 2006 2.18
25 The FaceBase Consortium: a comprehensive program to facilitate craniofacial research. Dev Biol 2011 2.16
26 Altered gene expression profiles in nasal respiratory epithelium reflect stable versus acute childhood asthma. J Allergy Clin Immunol 2005 2.16
27 Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart. J Clin Invest 2007 2.12
28 Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy. Nat Med 2002 2.05
29 Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease. Nature 2009 2.05
30 Independent and overlapping transcriptional activation during liver development and regeneration in mice. Hepatology 2002 2.02
31 MicroRNA-21 limits in vivo immune response-mediated activation of the IL-12/IFN-gamma pathway, Th1 polarization, and the severity of delayed-type hypersensitivity. J Immunol 2011 2.00
32 Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenic mice. J Biol Chem 2006 1.92
33 Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis. Proc Natl Acad Sci U S A 2007 1.86
34 A catalogue of gene expression in the developing kidney. Kidney Int 2003 1.83
35 MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors. J Clin Invest 2012 1.83
36 Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Dev Biol 2009 1.83
37 Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues. Cancer Res 2006 1.80
38 MicroRNA signature in patients with eosinophilic esophagitis, reversibility with glucocorticoids, and assessment as disease biomarkers. J Allergy Clin Immunol 2012 1.79
39 ToppCluster: a multiple gene list feature analyzer for comparative enrichment clustering and network-based dissection of biological systems. Nucleic Acids Res 2010 1.75
40 Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9. Bone 2005 1.68
41 Wnt/beta-catenin signaling is required for development of the exocrine pancreas. BMC Dev Biol 2007 1.68
42 Clonality analysis after retroviral-mediated gene transfer to CD34+ cells from the cord blood of ADA-deficient SCID neonates. Nat Med 2003 1.65
43 MiR-223 deficiency increases eosinophil progenitor proliferation. J Immunol 2013 1.60
44 Transcriptional profiles of intestinal tumors in Apc(Min) mice are unique from those of embryonic intestine and identify novel gene targets dysregulated in human colorectal tumors. Cancer Res 2005 1.58
45 PolyDoms: a whole genome database for the identification of non-synonymous coding SNPs with the potential to impact disease. Nucleic Acids Res 2006 1.58
46 Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism. Proc Natl Acad Sci U S A 2009 1.58
47 Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis. Arthritis Rheum 2009 1.56
48 Unbiased analysis of RB-mediated transcriptional repression identifies novel targets and distinctions from E2F action. Cancer Res 2002 1.55
49 Transcript signatures in experimental asthma: identification of STAT6-dependent and -independent pathways. J Immunol 2004 1.54
50 Genes that confer the identity of the renin cell. J Am Soc Nephrol 2011 1.52
51 Prolonged exposure to reduced levels of androgen accelerates prostate cancer progression in Nkx3.1; Pten mutant mice. Cancer Res 2007 1.51
52 High-throughput detection of mutations responsible for childhood hearing loss using resequencing microarrays. BMC Biotechnol 2010 1.45
53 A thrombospondin-dependent pathway for a protective ER stress response. Cell 2012 1.45
54 Activator protein-1 transcription factors are associated with progression and recurrence of prostate cancer. Cancer Res 2008 1.42
55 Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene. EMBO Mol Med 2009 1.41
56 Genomic responses of the brain to ischemic stroke, intracerebral haemorrhage, kainate seizures, hypoglycemia, and hypoxia. Eur J Neurosci 2002 1.37
57 Credentialing a preclinical mouse model of alveolar rhabdomyosarcoma. Cancer Res 2009 1.37
58 RB loss abrogates cell cycle control and genome integrity to promote liver tumorigenesis. Gastroenterology 2007 1.36
59 Novel resequencing chip customized to diagnose mutations in patients with inherited syndromes of intrahepatic cholestasis. Gastroenterology 2006 1.35
60 Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas. J Clin Invest 2010 1.35
61 Functional evolution of the p53 regulatory network through its target response elements. Proc Natl Acad Sci U S A 2008 1.34
62 The transcription factor GATA-6 regulates pathological cardiac hypertrophy. Circ Res 2010 1.32
63 Identification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease. EMBO Mol Med 2013 1.32
64 Genomics of the periinfarction cortex after focal cerebral ischemia. J Cereb Blood Flow Metab 2003 1.32
65 Microarray and comparative genomics-based identification of genes and gene regulatory regions of the mouse immune system. BMC Genomics 2004 1.25
66 Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo. Proc Natl Acad Sci U S A 2011 1.23
67 mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma. Sci Transl Med 2012 1.21
68 The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer. Cancer Res 2008 1.21
69 Shared gene expression profiles in developing heart valves and osteoblast progenitor cells. Physiol Genomics 2008 1.21
70 Essential requirement of apolipoprotein J (clusterin) signaling for IkappaB expression and regulation of NF-kappaB activity. J Biol Chem 2003 1.20
71 Dynamic interaction between T cell-mediated beta-cell damage and beta-cell repair in the run up to autoimmune diabetes of the NOD mouse. Physiol Genomics 2005 1.19
72 CisMols Analyzer: identification of compositionally similar cis-element clusters in ortholog conserved regions of coordinately expressed genes. Nucleic Acids Res 2005 1.18
73 GenomeTrafac: a whole genome resource for the detection of transcription factor binding site clusters associated with conventional and microRNA encoding genes conserved between mouse and human gene orthologs. Nucleic Acids Res 2006 1.17
74 Calcineurin Abeta gene targeting predisposes the myocardium to acute ischemia-induced apoptosis and dysfunction. Circ Res 2003 1.16
75 PhenoHM: human-mouse comparative phenome-genome server. Nucleic Acids Res 2010 1.16
76 Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets. Arthritis Rheum 2009 1.15
77 The p160 steroid receptor coactivator 2, SRC-2, regulates murine endometrial function and regulates progesterone-independent and -dependent gene expression. Endocrinology 2007 1.15
78 Novel genes and functional relationships in the adult mouse gastrointestinal tract identified by microarray analysis. Gastroenterology 2002 1.15
79 Inferring novel disease indications for known drugs by semantically linking drug action and disease mechanism relationships. BMC Bioinformatics 2009 1.12
80 Concerns over interspecies transcriptional comparisons in mice and humans after trauma. Proc Natl Acad Sci U S A 2013 1.12
81 Targeted imaging of colonic tumors in smad3-/- mice discriminates cancer and inflammation. Mol Cancer Res 2007 1.11
82 Microevolution of group A streptococci in vivo: capturing regulatory networks engaged in sociomicrobiology, niche adaptation, and hypervirulence. PLoS One 2010 1.09
83 Apolipoprotein J/clusterin prevents a progressive glomerulopathy of aging. Mol Cell Biol 2002 1.09
84 Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity. J Clin Invest 2013 1.08
85 Human blood genomics: distinct profiles for gender, age and neurofibromatosis type 1. Brain Res Mol Brain Res 2004 1.08
86 Bridging the gap between systems biology and medicine. Genome Med 2009 1.07
87 Transcriptional response to persistent beta2-adrenergic receptor signaling reveals regulation of phospholamban, which alters airway contractility. Physiol Genomics 2006 1.05
88 Transcriptome signature of irreversible senescence in human papillomavirus-positive cervical cancer cells. Proc Natl Acad Sci U S A 2003 1.05
89 Gene expression profiles of Mst1r-deficient mice during nickel-induced acute lung injury. Am J Respir Cell Mol Biol 2005 1.03
90 Comprehensive microarray analysis of Hoxa11/Hoxd11 mutant kidney development. Dev Biol 2006 1.02
91 Transcriptional adaptation to cystic fibrosis transmembrane conductance regulator deficiency. J Biol Chem 2002 1.02
92 Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis. Arthritis Res Ther 2010 1.01
93 Microarray analysis of gene expression in cultured skin substitutes compared with native human skin. J Invest Dermatol 2005 1.01
94 Microarray analysis of gene expression during early stages of mild and severe cardiac hypertrophy. Physiol Genomics 2006 1.00
95 Modulation of chromatin position and gene expression by HDAC4 interaction with nucleoporins. J Cell Biol 2011 1.00
96 Staging of biliary atresia at diagnosis by molecular profiling of the liver. Genome Med 2010 0.99
97 Microarray-based discovery of highly expressed olfactory mucosal genes: potential roles in the various functions of the olfactory system. Physiol Genomics 2003 0.99
98 Absence of poly(ADP-ribose)polymerase-1 alters nuclear factor-kappa B activation and gene expression of apoptosis regulators after reperfusion injury. Mol Med 2003 0.98
99 Activation of a novel long-chain free fatty acid generation and export system in mitochondria of diabetic rat hearts. Am J Physiol Cell Physiol 2006 0.98
100 Ras-driven transcriptome analysis identifies aurora kinase A as a potential malignant peripheral nerve sheath tumor therapeutic target. Clin Cancer Res 2012 0.98
101 Protective role of clusterin/apolipoprotein J against neointimal hyperplasia via antiproliferative effect on vascular smooth muscle cells and cytoprotective effect on endothelial cells. Arterioscler Thromb Vasc Biol 2009 0.97
102 Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data. BMC Bioinformatics 2007 0.97
103 An overview of custom array sequencing. Curr Protoc Hum Genet 2009 0.96
104 Neural system-enriched gene expression: relationship to biological pathways and neurological diseases. Physiol Genomics 2004 0.96
105 Critical role for transcription factor AP-2alpha in human trophoblast differentiation. Physiol Genomics 2004 0.95
106 Genomic analysis of alachlor-induced oncogenesis in rat olfactory mucosa. Physiol Genomics 2002 0.95
107 Engineered human skin substitutes undergo large-scale genomic reprogramming and normal skin-like maturation after transplantation to athymic mice. J Invest Dermatol 2009 0.94
108 Genetic profiling reveals global changes in multiple biological pathways in the hearts of Na, K-ATPase alpha 1 isoform haploinsufficient mice. Cell Physiol Biochem 2005 0.94
109 Microarray analysis of focal segmental glomerulosclerosis. Am J Nephrol 2004 0.94
110 Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon. Proc Natl Acad Sci U S A 2008 0.93
111 Human coronary artery perivascular adipocytes overexpress genes responsible for regulating vascular morphology, inflammation, and hemostasis. Physiol Genomics 2013 0.93
112 Cyclin D1 is a selective modifier of androgen-dependent signaling and androgen receptor function. J Biol Chem 2011 0.92
113 Alternatively spliced tissue factor contributes to tumor spread and activation of coagulation in pancreatic ductal adenocarcinoma. Int J Cancer 2013 0.91
114 Inhibition of nitric oxide restores surfactant gene expression following nickel-induced acute lung injury. Am J Respir Cell Mol Biol 2003 0.91
115 LMO7 mediates cell-specific activation of the Rho-myocardin-related transcription factor-serum response factor pathway and plays an important role in breast cancer cell migration. Mol Cell Biol 2011 0.91
116 SPDEF functions as a colorectal tumor suppressor by inhibiting β-catenin activity. Gastroenterology 2013 0.91
117 Gene expression profile analysis of mouse colon embryonic development. Genesis 2005 0.91
118 Targeted ablation of miR-21 decreases murine eosinophil progenitor cell growth. PLoS One 2013 0.90
119 Identifying disease-causal genes using Semantic Web-based representation of integrated genomic and phenomic knowledge. J Biomed Inform 2008 0.90
120 Genetic susceptibility to nickel-induced acute lung injury. Chemosphere 2003 0.89
121 Keloid-derived keratinocytes exhibit an abnormal gene expression profile consistent with a distinct causal role in keloid pathology. Wound Repair Regen 2013 0.89
122 Differential regulation of activator protein-1 and heat shock factor-1 in myocardial ischemia and reperfusion injury: role of poly(ADP-ribose) polymerase-1. Am J Physiol Heart Circ Physiol 2003 0.89
123 Comparative gene expression analysis of genital tubercle development reveals a putative appendicular Wnt7 network for the epidermal differentiation. Dev Biol 2010 0.88
124 Maternal influences on the transmission of leukocyte gene expression profiles in population samples from Brisbane, Australia. PLoS One 2010 0.88
125 Onecut-2 knockout mice fail to thrive during early postnatal period and have altered patterns of gene expression in small intestine. Physiol Genomics 2010 0.87
126 Gene expression analysis identifies potential biomarkers of neurofibromatosis type 1 including adrenomedullin. Clin Cancer Res 2010 0.86
127 Temperature-dependent modification and activation of B-MYB: implications for cell survival. J Biol Chem 2004 0.85
128 Large-scale reprogramming of cranial neural crest gene expression by retinoic acid exposure. Physiol Genomics 2004 0.85
129 Nonproteolytic properties of murine alternatively spliced tissue factor: implications for integrin-mediated signaling in murine models. Mol Med 2012 0.85
130 Cytomegalovirus infection of human syncytiotrophoblast cells strongly interferes with expression of genes involved in placental differentiation and tissue integrity. Pediatr Res 2007 0.85
131 Differential coupling of Arg- and Gly389 polymorphic forms of the beta1-adrenergic receptor leads to pathogenic cardiac gene regulatory programs. Physiol Genomics 2008 0.84
132 Multiple interactions between the alpha 2C- and beta1-adrenergic receptors influence heart failure survival. BMC Med Genet 2008 0.84
133 Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cells. J Clin Invest 2015 0.84
134 Computational drug repositioning through heterogeneous network clustering. BMC Syst Biol 2013 0.84
135 The differential effect of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers with respect to foot ulcer and limb amputation in those with diabetes. Wound Repair Regen 2010 0.84
136 G-CSF drives a posttraumatic immune program that protects the host from infection. J Immunol 2014 0.83
137 Temporal gene expression profiling reveals CEBPD as a candidate regulator of brain disease in prosaposin deficient mice. BMC Neurosci 2008 0.83
138 Essential role of clusterin in pancreas regeneration. Dev Dyn 2011 0.83
139 Growth factor independent-1 maintains Notch1-dependent transcriptional programming of lymphoid precursors. PLoS Genet 2013 0.83
140 Molecular engineering and validation of an oncolytic herpes simplex virus type 1 transcriptionally targeted to midkine-positive tumors. J Gene Med 2010 0.82
141 A Drosophila model of the neurodegenerative disease SCA17 reveals a role of RBP-J/Su(H) in modulating the pathological outcome. Hum Mol Genet 2011 0.82
142 Computational approaches for human disease gene prediction and ranking. Adv Exp Med Biol 2014 0.82
143 Deficiency of clusterin inhibits neointimal hyperplasia after vascular injury. J Atheroscler Thromb 2009 0.79
144 Embrace diversity! Systems genetics-enabled discovery of disease networks. Physiol Genomics 2009 0.79
145 Microarray analysis of active cardiac remodeling genes in a familial hypertrophic cardiomyopathy mouse model rescued by a phospholamban knockout. Physiol Genomics 2013 0.78
146 Mining human phenome to investigate modularity of complex disorders. Summit on Translat Bioinforma 2008 0.78
147 PRECISION MEDICINE: DATA AND DISCOVERY FOR IMPROVED HEALTH AND THERAPY. Pac Symp Biocomput 2016 0.78
148 Cellular expression patterns of genes upregulated in murine and human colonic neoplasms. J Histochem Cytochem 2008 0.75
149 Gene expression microarray data analysis of decidual and placental cell differentiation. Methods Mol Med 2006 0.75
150 Structure of the 5' portion of the human plakoglobin gene. J Invest Dermatol 2002 0.75
151 PRECISION MEDICINE: DATA AND DISCOVERY FOR IMPROVED HEALTH AND THERAPY. Pac Symp Biocomput 2016 0.75
152 Erratum: Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling. Nat Med 2017 0.75
153 PRECISION MEDICINE: FROM DIPLOTYPES TO DISPARITIES TOWARDS IMPROVED HEALTH AND THERAPIES. Pac Symp Biocomput 2018 0.75