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Expression of cone-photoreceptor-specific antigens in a cell line derived from retinal tumors in transgenic mice.
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PLoS One
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2006
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3
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Biochem J
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Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa.
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2009
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DNA nanoparticle-mediated ABCA4 delivery rescues Stargardt dystrophy in mice.
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J Clin Invest
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12
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Retinal stem cells transplanted into models of late stages of retinitis pigmentosa preferentially adopt a glial or a retinal ganglion cell fate.
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Invest Ophthalmol Vis Sci
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2007
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Differential requirements for retinal degeneration slow intermolecular disulfide-linked oligomerization in rods versus cones.
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Hum Mol Genet
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Biochemistry
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Invest Ophthalmol Vis Sci
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2003
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Ocular delivery of compacted DNA-nanoparticles does not elicit toxicity in the mouse retina.
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PLoS One
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Role of the second intradiscal loop of peripherin/rds in homo and hetero associations.
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Biochemistry
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18
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The role of Rds in outer segment morphogenesis and human retinal disease.
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Ophthalmic Genet
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Differences in RDS trafficking, assembly and function in cones versus rods: insights from studies of C150S-RDS.
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Hum Mol Genet
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Retinal angiogenesis in the Ins2(Akita) mouse model of diabetic retinopathy.
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Invest Ophthalmol Vis Sci
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S/MAR-containing DNA nanoparticles promote persistent RPE gene expression and improvement in RPE65-associated LCA.
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Hum Mol Genet
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Molecular characterization of the skate peripherin/rds gene: relationship to its orthologues and paralogues.
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Nanoparticle-mediated gene transfer specific to retinal pigment epithelial cells.
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Biomaterials
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Comparative analysis of DNA nanoparticles and AAVs for ocular gene delivery.
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Nanoparticles for retinal gene therapy.
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Prog Retin Eye Res
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Drug and gene delivery to the back of the eye: from bench to bedside.
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Invest Ophthalmol Vis Sci
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Direct gene transfer with compacted DNA nanoparticles in retinal pigment epithelial cells: expression, repeat delivery and lack of toxicity.
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Nanomedicine (Lond)
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Expression profiling after retinal detachment and reattachment: a possible role for aquaporin-0.
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Defects in the outer limiting membrane are associated with rosette development in the Nrl-/- retina.
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PLoS One
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Increased cone sensitivity to ABCA4 deficiency provides insight into macular vision loss in Stargardt's dystrophy.
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Biochim Biophys Acta
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Genetic supplementation of RDS alleviates a loss-of-function phenotype in C214S model of retinitis pigmentosa.
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Biochemical analysis of phenotypic diversity associated with mutations in codon 244 of the retinal degeneration slow gene.
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Biochemistry
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Late-onset cone photoreceptor degeneration induced by R172W mutation in Rds and partial rescue by gene supplementation.
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Structural and functional relationships between photoreceptor tetraspanins and other superfamily members.
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Cell Mol Life Sci
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Differential distribution of proteins and lipids in detergent-resistant and detergent-soluble domains in rod outer segment plasma membranes and disks.
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J Neurochem
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Absence of functional and structural abnormalities associated with expression of EGFP in the retina.
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Gene therapy for Stargardt disease associated with ABCA4 gene.
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A review of therapeutic prospects of non-viral gene therapy in the retinal pigment epithelium.
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Differential developmental deficits in retinal function in the absence of either protein tyrosine sulfotransferase-1 or -2.
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Persistence of non-viral vector mediated RPE65 expression: case for viability as a gene transfer therapy for RPE-based diseases.
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RDS in cones does not interact with the beta subunit of the cyclic nucleotide gated channel.
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Mouse models of human retinal disease caused by expression of mutant rhodopsin. A valuable tool for the assessment of novel gene therapies.
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Fibulin 2, a tyrosine O-sulfated protein, is up-regulated following retinal detachment.
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A perspective on the role of the extracellular matrix in progressive retinal degenerative disorders.
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Synthesis and characterization of glycol chitosan DNA nanoparticles for retinal gene delivery.
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AAV and compacted DNA nanoparticles for the treatment of retinal disorders: challenges and future prospects.
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Episomal maintenance of S/MAR-containing non-viral vectors for RPE-based diseases.
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A 350 bp region of the proximal promoter of Rds drives cell-type specific gene expression.
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Structural characterization of the second intra-discal loop of the photoreceptor tetraspanin RDS.
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In vitro analysis of ribozyme-mediated knockdown of an ADRP associated rhodopsin mutation.
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Overexpression of ROM-1 in the cone-dominant retina.
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