Published in J Biol Chem on October 29, 2007
New insights into form and function of fibronectin splice variants. J Pathol (2008) 1.80
FibronectinEDA promotes chronic cutaneous fibrosis through Toll-like receptor signaling. Sci Transl Med (2014) 1.72
Fibronectins in vascular morphogenesis. Angiogenesis (2009) 1.66
Loss of integrin alpha9beta1 results in defects in proliferation, causing poor re-epithelialization during cutaneous wound healing. J Invest Dermatol (2008) 1.17
EMILIN1-α4/α9 integrin interaction inhibits dermal fibroblast and keratinocyte proliferation. J Cell Biol (2011) 1.05
Integrin alpha9beta1 mediates enhanced cell migration through nitric oxide synthase activity regulated by Src tyrosine kinase. J Cell Sci (2009) 1.03
Fibronectin extra domain A (EDA) sustains CD133(+)/CD44(+) subpopulation of colorectal cancer cells. Stem Cell Res (2013) 1.00
Polydom/SVEP1 is a ligand for integrin α9β1. J Biol Chem (2012) 0.93
Fibronectin extra domain-A promotes hepatic stellate cell motility but not differentiation into myofibroblasts. Gastroenterology (2011) 0.93
Integrin alpha9beta1: Unique signaling pathways reveal diverse biological roles. Cell Adh Migr (2010) 0.93
Fibronectin: functional character and role in alcoholic liver disease. World J Gastroenterol (2011) 0.89
The first type III repeat in fibronectin activates an inflammatory pathway in dermal fibroblasts. J Biol Chem (2010) 0.87
The group A streptococcal collagen-like protein-1, Scl1, mediates biofilm formation by targeting the extra domain A-containing variant of cellular fibronectin expressed in wounded tissue. Mol Microbiol (2012) 0.86
Integrin Regulation of Epidermal Functions in Wounds. Adv Wound Care (New Rochelle) (2014) 0.85
Changes in plasma fibronectin isoform levels predict distinct clinical outcomes in critically ill patients. Biomark Insights (2011) 0.84
Interaction between the extracellular matrix and lymphatics: consequences for lymphangiogenesis and lymphatic function. Matrix Biol (2010) 0.84
Fibronectin Mechanobiology Regulates Tumorigenesis. Cell Mol Bioeng (2015) 0.81
The TLR4 agonist fibronectin extra domain A is cryptic, exposed by elastase-2; use in a fibrin matrix cancer vaccine. Sci Rep (2015) 0.80
Regulation of the innate immune response by fibronectin: synergism between the III-1 and EDA domains. PLoS One (2014) 0.80
Eukaryotic translation elongation factor 1A induces anoikis by triggering cell detachment. J Biol Chem (2012) 0.80
EDA-containing fibronectin increases proliferation of embryonic stem cells. PLoS One (2013) 0.78
The α4β1 integrin and the EDA domain of fibronectin regulate a profibrotic phenotype in dermal fibroblasts. Matrix Biol (2014) 0.77
EDA Fibronectin in Keloids Create a Vicious Cycle of Fibrotic Tumor Formation. J Invest Dermatol (2015) 0.76
Integrin-mediated regulation of epidermal wound functions. Cell Tissue Res (2016) 0.75
Collagen-like proteins of pathogenic streptococci. Mol Microbiol (2017) 0.75
Biochemical characterization of PE_PGRS61 family protein of Mycobacterium tuberculosis H37Rv reveals the binding ability to fibronectin. Iran J Basic Med Sci (2016) 0.75
The Phosphorylation and Distribution of Cortactin Downstream of Integrin α9β1 Affects Cancer Cell Behaviour. Sci Rep (2016) 0.75
Suppression of integrin α3β1 by α9β1 in the epidermis controls the paracrine resolution of wound angiogenesis. J Cell Biol (2017) 0.75
Irigenin, a novel lead from Western Himalayan chemiome inhibits Fibronectin-Extra Domain A induced metastasis in Lung cancer cells. Sci Rep (2016) 0.75
Differences between the early and advanced stages of rheumatoid arthritis in the expression of EDA-containing fibronectin. Rheumatol Int (2009) 0.75
Complete replication of hepatitis C virus in cell culture. Science (2005) 18.59
The genome of the sea urchin Strongylocentrotus purpuratus. Science (2006) 6.41
Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis. Cancer Cell (2011) 6.21
Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins. Nat Med (2002) 4.87
Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhere. Mol Biol Cell (2002) 4.27
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease. Nat Med (2008) 3.69
Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin. Cancer Cell (2003) 3.68
Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells. J Cell Biol (2003) 3.39
Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis. Proc Natl Acad Sci U S A (2002) 3.10
CD40L stabilizes arterial thrombi by a beta3 integrin--dependent mechanism. Nat Med (2002) 2.77
The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain. Proc Natl Acad Sci U S A (2012) 2.51
The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices. Mol Cell Proteomics (2011) 2.43
p120-Catenin regulates clathrin-dependent endocytosis of VE-cadherin. Mol Biol Cell (2005) 2.37
The Alzheimer's peptides Abeta40 and 42 adopt distinct conformations in water: a combined MD / NMR study. J Mol Biol (2007) 2.35
Tumstatin, an endothelial cell-specific inhibitor of protein synthesis. Science (2002) 2.28
Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins. Proc Natl Acad Sci U S A (2007) 2.18
Selective ablation of alphav integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death. Development (2004) 2.14
GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis. Proc Natl Acad Sci U S A (2006) 2.08
Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases. Mol Cancer Res (2008) 1.99
Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies. Arterioscler Thromb Vasc Biol (2002) 1.97
GPR56 regulates pial basement membrane integrity and cortical lamination. J Neurosci (2008) 1.93
A system for Cre-regulated RNA interference in vivo. Proc Natl Acad Sci U S A (2008) 1.87
Decreased plasma fibronectin leads to delayed thrombus growth in injured arterioles. Arterioscler Thromb Vasc Biol (2006) 1.84
The EIIIA segment of fibronectin is a ligand for integrins alpha 9beta 1 and alpha 4beta 1 providing a novel mechanism for regulating cell adhesion by alternative splicing. J Biol Chem (2002) 1.81
Plasma fibronectin promotes thrombus growth and stability in injured arterioles. Proc Natl Acad Sci U S A (2003) 1.74
The echinoderm adhesome. Dev Biol (2006) 1.71
Fibronectins in vascular morphogenesis. Angiogenesis (2009) 1.66
Abeta42 is more rigid than Abeta40 at the C terminus: implications for Abeta aggregation and toxicity. J Mol Biol (2006) 1.64
Defective associations between blood vessels and brain parenchyma lead to cerebral hemorrhage in mice lacking alphav integrins. Mol Cell Biol (2002) 1.55
Manganese superoxide dismutase enhances the invasive and migratory activity of tumor cells. Cancer Res (2007) 1.52
VE-cadherin-p120 interaction is required for maintenance of endothelial barrier function. Am J Physiol Lung Cell Mol Physiol (2003) 1.50
Orai1-mediated I (CRAC) is essential for neointima formation after vascular injury. Circ Res (2011) 1.50
p120-catenin binding masks an endocytic signal conserved in classical cadherins. J Cell Biol (2012) 1.48
RhoA and Rho-kinase dependent and independent signals mediate TGF-beta-induced pulmonary endothelial cytoskeletal reorganization and permeability. Am J Physiol Lung Cell Mol Physiol (2004) 1.48
Identifying the subproteome of kinetically stable proteins via diagonal 2D SDS/PAGE. Proc Natl Acad Sci U S A (2007) 1.47
A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis. Nat Commun (2012) 1.47
NMR R1 rho rotating-frame relaxation with weak radio frequency fields. J Am Chem Soc (2004) 1.46
Endothelial alpha5 and alphav integrins cooperate in remodeling of the vasculature during development. Development (2010) 1.42
In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling. Cancer Cell (2013) 1.42
Disulfide bond isomerization in basic pancreatic trypsin inhibitor: multisite chemical exchange quantified by CPMG relaxation dispersion and chemical shift modeling. J Am Chem Soc (2003) 1.42
The initial hours of metastasis: the importance of cooperative host-tumor cell interactions during hematogenous dissemination. Cancer Discov (2012) 1.40
Multiple cardiovascular defects caused by the absence of alternatively spliced segments of fibronectin. Dev Biol (2007) 1.38
Src-induced tyrosine phosphorylation of VE-cadherin is not sufficient to decrease barrier function of endothelial monolayers. J Biol Chem (2010) 1.35
Alpha4beta1 integrin and erythropoietin mediate temporally distinct steps in erythropoiesis: integrins in red cell development. J Cell Biol (2007) 1.35
Direct test of potential roles of EIIIA and EIIIB alternatively spliced segments of fibronectin in physiological and tumor angiogenesis. Mol Cell Biol (2004) 1.34
Tumor-secreted vascular endothelial growth factor-C is necessary for prostate cancer lymphangiogenesis, but lymphangiogenesis is unnecessary for lymph node metastasis. Cancer Res (2005) 1.33
Increased primary tumor growth in mice null for beta3- or beta3/beta5-integrins or selectins. Proc Natl Acad Sci U S A (2004) 1.33
Requirement for the NF-kappaB family member RelA in the development of secondary lymphoid organs. J Exp Med (2002) 1.32
Activation of p38 has opposing effects on the proliferation and migration of endothelial cells. J Biol Chem (2005) 1.32
p120-catenin inhibits VE-cadherin internalization through a Rho-independent mechanism. Mol Biol Cell (2009) 1.32
Solution NMR and computer simulation studies of active site loop motion in triosephosphate isomerase. Biochemistry (2006) 1.31
Abeta40 protects non-toxic Abeta42 monomer from aggregation. J Mol Biol (2007) 1.28
Rational stabilization of enzymes by computational redesign of surface charge-charge interactions. Proc Natl Acad Sci U S A (2009) 1.27
{gamma}-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: IMPLICATIONS FOR ALZHEIMER DISEASE. J Biol Chem (2007) 1.27
Regulation of endothelial barrier function and growth by VE-cadherin, plakoglobin, and beta-catenin. Am J Physiol Cell Physiol (2002) 1.26
Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins. J Am Chem Soc (2011) 1.25
Predicting interresidue contacts using templates and pathways. Proteins (2003) 1.24
Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver. BMC Cancer (2014) 1.23
αv Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice. J Clin Invest (2010) 1.23
Atomic-level characterization of the ensemble of the Aβ(1-42) monomer in water using unbiased molecular dynamics simulations and spectral algorithms. J Mol Biol (2010) 1.23
Sphingosine 1-phosphate rapidly increases endothelial barrier function independently of VE-cadherin but requires cell spreading and Rho kinase. Am J Physiol Cell Physiol (2007) 1.22
Activated Ras induces a proangiogenic phenotype in primary endothelial cells. Oncogene (2004) 1.21
Lymphatic or hematogenous dissemination: how does a metastatic tumor cell decide? Cell Cycle (2006) 1.21
CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis. Proc Natl Acad Sci U S A (2011) 1.20
Solution NMR spin relaxation methods for characterizing chemical exchange in high-molecular-weight systems. Methods Enzymol (2005) 1.19
Structure-function analysis reveals discrete beta3 integrin inside-out and outside-in signaling pathways in platelets. Blood (2006) 1.19
Loss of integrin alpha9beta1 results in defects in proliferation, causing poor re-epithelialization during cutaneous wound healing. J Invest Dermatol (2008) 1.17
p120-Catenin is required for mouse vascular development. Circ Res (2010) 1.16
Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters. Elife (2014) 1.16
Complementation and reconstitution of fluorescence from circularly permuted and truncated green fluorescent protein. Biochemistry (2009) 1.16
Protein 4.1B suppresses prostate cancer progression and metastasis. Proc Natl Acad Sci U S A (2007) 1.16
Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner. Proc Natl Acad Sci U S A (2011) 1.13
Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis. Development (2011) 1.13
Effect of lapatinib on the development of estrogen receptor-negative mammary tumors in mice. J Natl Cancer Inst (2009) 1.13
Highly conserved histidine plays a dual catalytic role in protein splicing: a pKa shift mechanism. J Am Chem Soc (2009) 1.12
p38 MAPK activation by TGF-beta1 increases MLC phosphorylation and endothelial monolayer permeability. Am J Physiol Lung Cell Mol Physiol (2002) 1.12
Aβ monomers transiently sample oligomer and fibril-like configurations: ensemble characterization using a combined MD/NMR approach. J Mol Biol (2013) 1.12
GPR56 Regulates VEGF production and angiogenesis during melanoma progression. Cancer Res (2011) 1.11
Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies. Chem Rev (2015) 1.10
Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1. Int J Cancer (2009) 1.10
Efficient remote homology detection using local structure. Bioinformatics (2003) 1.10
Residues SFQ (173-175) in the large extracellular loop of CD9 are required for gamete fusion. Development (2002) 1.09
GPR56 and TG2: possible roles in suppression of tumor growth by the microenvironment. Cell Cycle (2007) 1.09
A direct test of potential roles for beta3 and beta5 integrins in growth and metastasis of murine mammary carcinomas. Cancer Res (2005) 1.08
Trends in blood pressure and hypertension among Chinese children and adolescents: China Health and Nutrition Surveys 1991-2004. Blood Press (2010) 1.07
Non-sequential structure-based alignments reveal topology-independent core packing arrangements in proteins. Bioinformatics (2004) 1.07
Influence of physical inactivity on associations between single nucleotide polymorphisms and genetic predisposition to childhood obesity. Am J Epidemiol (2011) 1.07
An interaction between {alpha}v{beta}8 integrin and Band 4.1B via a highly conserved region of the Band 4.1 C-terminal domain. Proc Natl Acad Sci U S A (2005) 1.05
Measuring gene functional similarity based on group-wise comparison of GO terms. Bioinformatics (2013) 1.05
The spatial and temporal expression patterns of integrin alpha9beta1 and one of its ligands, the EIIIA segment of fibronectin, in cutaneous wound healing. J Invest Dermatol (2004) 1.05
Association of glutathione S-transferases polymorphisms (GSTM1 and GSTT1) with senile cataract: a meta-analysis. Invest Ophthalmol Vis Sci (2010) 1.04
Comparison of three amyloid assembly inhibitors: the sugar scyllo-inositol, the polyphenol epigallocatechin gallate, and the molecular tweezer CLR01. ACS Chem Neurosci (2012) 1.04
Stimulation of extracellular matrix remodeling by the first type III repeat in fibronectin. J Cell Sci (2003) 1.04
A novel murine model of fetal and neonatal alloimmune thrombocytopenia: response to intravenous IgG therapy. Blood (2005) 1.03
pK(a) coupling at the intein active site: implications for the coordination mechanism of protein splicing with a conserved aspartate. J Am Chem Soc (2011) 1.02
Transforming growth factor-β1-induced transcript 1 protein, a novel marker for smooth muscle contractile phenotype, is regulated by serum response factor/myocardin protein. J Biol Chem (2011) 1.01
Surface plasmon resonance and nuclear magnetic resonance studies of ABAD-Abeta interaction. Biochemistry (2007) 1.01
Spirochete-platelet attachment and thrombocytopenia in murine relapsing fever borreliosis. Blood (2003) 1.01