PubRank

Stephen C Strom

Author PubWeight™ 110.21‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mapping the genetic architecture of gene expression in human liver. PLoS Biol 2008 19.44
2 Differentiation and transplantation of human embryonic stem cell-derived hepatocytes. Gastroenterology 2008 3.99
3 Concise review: isolation and characterization of cells from human term placenta: outcome of the first international Workshop on Placenta Derived Stem Cells. Stem Cells 2007 3.39
4 Human hepatocyte transplantation: worldwide results. Transplantation 2006 3.02
5 Stem cell characteristics of amniotic epithelial cells. Stem Cells 2005 2.66
6 Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver. Genome Res 2010 2.06
7 A whole-organ regenerative medicine approach for liver replacement. Tissue Eng Part C Methods 2011 1.60
8 Maintenance of human hepatocyte function in vitro by liver-derived extracellular matrix gels. Tissue Eng Part A 2010 1.50
9 Isolated hepatocyte transplantation in an infant with a severe urea cycle disorder. Pediatrics 2003 1.49
10 Amnion-derived pluripotent/multipotent stem cells. Stem Cell Rev 2006 1.48
11 Identification of oxysterol 7alpha-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor alpha (RORalpha) (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3). Mol Pharmacol 2007 1.46
12 Barriers to the successful treatment of liver disease by hepatocyte transplantation. J Hepatol 2010 1.41
13 The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor. Biochemistry 2010 1.32
14 Improving the techniques for human hepatocyte transplantation: report from a consensus meeting in London. Cell Transplant 2012 1.31
15 Frequent aneuploidy among normal human hepatocytes. Gastroenterology 2011 1.30
16 Gene expression profiling and differentiation assessment in primary human hepatocyte cultures, established hepatoma cell lines, and human liver tissues. Toxicol Appl Pharmacol 2007 1.29
17 Induction and inhibition of cytochromes P450 by the St. John's wort constituent hyperforin in human hepatocyte cultures. Drug Metab Dispos 2004 1.19
18 Human hepatocyte transplantation. Methods Mol Biol 2010 1.17
19 Development and application of purified tissue dissociation enzyme mixtures for human hepatocyte isolation. Cell Transplant 2011 1.16
20 Regulation of human hepatic hydroxysteroid sulfotransferase gene expression by the peroxisome proliferator-activated receptor alpha transcription factor. Mol Pharmacol 2005 1.14
21 Isolated hepatocyte transplantation for Crigler-Najjar syndrome type 1. Cell Transplant 2005 1.12
22 Evaluation of hepatotoxic potential of drugs by inhibition of bile-acid transport in cultured primary human hepatocytes and intact rats. Toxicol Sci 2003 1.08
23 ChREBP mediates glucose-stimulated pancreatic β-cell proliferation. Diabetes 2012 1.08
24 Positive and negative regulation of human hepatic hydroxysteroid sulfotransferase (SULT2A1) gene transcription by rifampicin: roles of hepatocyte nuclear factor 4alpha and pregnane X receptor. J Pharmacol Exp Ther 2007 1.07
25 Identification of stem cell marker-positive cells by immunofluorescence in term human amnion. J Reprod Immunol 2007 1.06
26 MicroRNA hsa-miR-613 targets the human LXRα gene and mediates a feedback loop of LXRα autoregulation. Mol Endocrinol 2011 1.05
27 Effects of bergamottin on human and monkey drug-metabolizing enzymes in primary cultured hepatocytes. Drug Metab Dispos 2002 1.04
28 Sulforaphane- and phenethyl isothiocyanate-induced inhibition of aflatoxin B1-mediated genotoxicity in human hepatocytes: role of GSTM1 genotype and CYP3A4 gene expression. Toxicol Sci 2010 1.03
29 Isolation of amniotic epithelial stem cells. Curr Protoc Stem Cell Biol 2010 1.03
30 Side population cells derived from adult human liver generate hepatocyte-like cells in vitro. Dig Dis Sci 2005 1.02
31 Inhibition of hepatobiliary transport as a predictive method for clinical hepatotoxicity of nefazodone. Toxicol Sci 2006 0.99
32 Hepatic differentiation of amniotic epithelial cells. Hepatology 2011 0.99
33 Mouse fetal liver cells in artificial capillary beds in three-dimensional four-compartment bioreactors. Am J Pathol 2005 0.97
34 A functional polymorphism at the transcriptional initiation site in beta2-glycoprotein I (apolipoprotein H) associated with reduced gene expression and lower plasma levels of beta2-glycoprotein I. Eur J Biochem 2003 0.96
35 Hepatocyte transplantation improves phenotype and extends survival in a murine model of intermediate maple syrup urine disease. Mol Ther 2009 0.96
36 Expression profiling of interindividual variability following xenobiotic exposures in primary human hepatocyte cultures. Toxicol Appl Pharmacol 2008 0.96
37 Production of hepatocyte-like cells from human amnion. Methods Mol Biol 2009 0.95
38 Phenobarbital and phenytoin increased acetaminophen hepatotoxicity due to inhibition of UDP-glucuronosyltransferases in cultured human hepatocytes. Toxicol Sci 2005 0.94
39 Hepatocyte transplantation (HTx) corrects selected neurometabolic abnormalities in murine intermediate maple syrup urine disease (iMSUD). Biochim Biophys Acta 2009 0.94
40 Metabolism of 17alpha-hydroxyprogesterone caproate, an agent for preventing preterm birth, by fetal hepatocytes. Drug Metab Dispos 2010 0.93
41 Isolation of amniotic mesenchymal stem cells. Curr Protoc Stem Cell Biol 2010 0.92
42 New potential cell source for hepatocyte transplantation: discarded livers from metabolic disease liver transplants. Stem Cell Res 2013 0.92
43 A pregnane X receptor agonist with unique species-dependent stereoselectivity and its implications in drug development. Mol Pharmacol 2005 0.92
44 The second extracellular loop dictates Occludin-mediated HCV entry. Virology 2010 0.92
45 Regulation of CYP2B6 and CYP3A expression by hydroxymethylglutaryl coenzyme A inhibitors in primary cultured human hepatocytes. Drug Metab Dispos 2002 0.91
46 In vitro expansion of human hepatocytes is restricted by telomere-dependent replicative aging. Cell Transplant 2003 0.89
47 Effect of the St. John's wort constituent hyperforin on docetaxel metabolism by human hepatocyte cultures. Clin Cancer Res 2005 0.89
48 Placental stem cell correction of murine intermediate maple syrup urine disease. Hepatology 2013 0.89
49 Improved amino acid, bioenergetic metabolite and neurotransmitter profiles following human amnion epithelial cell transplant in intermediate maple syrup urine disease mice. Mol Genet Metab 2013 0.88
50 Preservation of hepatic phenotype in lentiviral-transduced primary human hepatocytes. Chem Biol Interact 2008 0.87
51 Hepatobiliary disposition of 17-OHPC and taurocholate in fetal human hepatocytes: a comparison with adult human hepatocytes. Drug Metab Dispos 2012 0.85
52 Genetic variation in aldo-keto reductase 1D1 (AKR1D1) affects the expression and activity of multiple cytochrome P450s. Drug Metab Dispos 2013 0.85
53 FoxO1 links hepatic insulin action to endoplasmic reticulum stress. Endocrinology 2010 0.84
54 Regulation of the human hydroxysteroid sulfotransferase (SULT2A1) by RORα and RORγ and its potential relevance to human liver diseases. Mol Endocrinol 2012 0.84
55 Clinical hepatocyte transplantation: practical limits and possible solutions. Eur Surg Res 2015 0.84
56 Study of the genetic determinants of UGT1A1 inducibility by phenobarbital in cultured human hepatocytes. Pharmacogenet Genomics 2006 0.84
57 Arsenite decreases CYP3A4 and RXRalpha in primary human hepatocytes. Drug Metab Dispos 2005 0.84
58 To be or not to be: generation of hepatocytes from cells outside the liver. Gastroenterology 2008 0.84
59 Status of bacterial colonization, Toll-like receptor expression and nuclear factor-kappa B activation in normal and diseased human livers. Clin Immunol 2010 0.83
60 Naive rat amnion-derived cell transplantation improved left ventricular function and reduced myocardial scar of postinfarcted heart. Cell Transplant 2009 0.83
61 Mice with chimeric livers are an improved model for human lipoprotein metabolism. PLoS One 2013 0.83
62 ATPase Class I Type 8B Member 1 and protein kinase C zeta induce the expression of the canalicular bile salt export pump in human hepatocytes. Pediatr Res 2010 0.83
63 Human pregnane X receptor activation and CYP3A4/CYP2B6 induction by 2,3-oxidosqualene:lanosterol cyclase inhibition. Drug Metab Dispos 2009 0.82
64 The history and use of human hepatocytes for the treatment of liver diseases: the first 100 patients. Curr Protoc Toxicol 2014 0.81
65 Rapid and sensitive assessment of human hepatocyte functions. Cell Transplant 2014 0.81
66 Ritonavir and efavirenz significantly alter the metabolism of erlotinib--an observation in primary cultures of human hepatocytes that is relevant to HIV patients with cancer. Drug Metab Dispos 2013 0.81
67 Hypothermic storage of human hepatocytes for transplantation. Cell Transplant 2014 0.81
68 Transport, metabolism, and hepatotoxicity of flutamide, drug-drug interaction with acetaminophen involving phase I and phase II metabolites. Chem Res Toxicol 2007 0.81
69 Regulation of CYP3A4 and CYP2B6 expression by liver X receptor agonists. Biochem Pharmacol 2007 0.81
70 Induction of cyp3a in primary cultures of human hepatocytes by ginkgolides a and B. Clin Exp Pharmacol Physiol 2007 0.80
71 Transactivation of a DR-1 PPRE by a human constitutive androstane receptor variant expressed from internal protein translation start sites. Nucleic Acids Res 2007 0.80
72 Hepatic organic anion transporting polypeptide transporter and thyroid hormone receptor interplay determines cholesterol and glucose homeostasis. Hepatology 2011 0.80
73 Pharmacokinetics of tacrolimus and mycophenolic acid are altered, but recover at different times during hepatic regeneration in rats. Drug Metab Dispos 2004 0.79
74 Potential barriers to human hepatocyte transplantation in MUP-uPAtg(⁺/⁺)Rag2⁻/⁻γC⁻/⁻ mice. Cell Transplant 2013 0.79
75 Modulation of aflatoxin B1-mediated genotoxicity in primary cultures of human hepatocytes by diindolylmethane, curcumin, and xanthohumols. Toxicol Sci 2009 0.79
76 A sensitive and specific CYP cocktail assay for the simultaneous assessment of human cytochrome P450 activities in primary cultures of human hepatocytes using LC-MS/MS. J Pharm Biomed Anal 2012 0.79
77 Bigger may not be better when it comes to hepatocytes. Liver Transpl 2006 0.79
78 The orphan nuclear receptor DAX-1 functions as a potent corepressor of the constitutive androstane receptor (NR1I3). Mol Pharmacol 2012 0.79
79 Long term cultures of primary human hepatocytes as an alternative to drug testing in animals. ALTEX 2009 0.78
80 Effect of rifampin and nelfinavir on the metabolism of methadone and buprenorphine in primary cultures of human hepatocytes. Drug Metab Dispos 2009 0.78
81 Activity and expression of various isoforms of uridine diphosphate glucuronosyltransferase are differentially regulated during hepatic regeneration in rats. Pharm Res 2005 0.77
82 Why do most human liver cytosol preparations lack xanthine oxidase activity? Drug Metab Dispos 2014 0.77
83 Embryonic and induced pluripotent stem cells as a model for liver disease. Crit Rev Biomed Eng 2009 0.77
84 Benzothiophene carboxylate derivatives as novel allosteric inhibitors of branched-chain α-ketoacid dehydrogenase kinase. J Biol Chem 2014 0.77
85 Regulation of the human cathepsin E gene by the constitutive androstane receptor. Arch Biochem Biophys 2007 0.76
86 Effects of green tea compounds on irinotecan metabolism. Drug Metab Dispos 2006 0.76
87 Increased reprogramming of human fetal hepatocytes compared with adult hepatocytes in feeder-free conditions. Cell Transplant 2013 0.76
88 Arsenic decreases RXRα-dependent transcription of CYP3A and suppresses immune regulators in hepatocytes. Int Immunopharmacol 2012 0.75