Published in Trends Immunol on November 05, 2007
Exploring the full spectrum of macrophage activation. Nat Rev Immunol (2008) 26.08
Graves' ophthalmopathy. N Engl J Med (2010) 4.24
Identification of a physiologically relevant endogenous ligand for PPARalpha in liver. Cell (2009) 3.26
Post-transcriptional regulons coordinate the initiation and resolution of inflammation. Nat Rev Immunol (2010) 2.08
The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention. Nat Rev Cancer (2012) 2.06
The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity. J Exp Med (2009) 1.95
NF-kappaB signaling: multiple angles to target OA. Curr Drug Targets (2010) 1.89
Molecular recognition of nitrated fatty acids by PPAR gamma. Nat Struct Mol Biol (2008) 1.67
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation. Proc Natl Acad Sci U S A (2009) 1.64
Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice. J Clin Invest (2011) 1.58
Role of peroxisome-proliferator-activated receptor beta/delta (PPARbeta/delta) in gastrointestinal tract function and disease. Clin Sci (Lond) (2008) 1.53
Nuclear receptors as therapeutic targets for Alzheimer's disease. Expert Opin Ther Targets (2011) 1.46
Rosiglitazone monotherapy in mild-to-moderate Alzheimer's disease: results from a randomized, double-blind, placebo-controlled phase III study. Dement Geriatr Cogn Disord (2010) 1.45
Mycobacterium tuberculosis activates human macrophage peroxisome proliferator-activated receptor gamma linking mannose receptor recognition to regulation of immune responses. J Immunol (2010) 1.37
Innate immune signalling at the intestinal epithelium in homeostasis and disease. EMBO Rep (2012) 1.37
The metabolism of proline as microenvironmental stress substrate. J Nutr (2008) 1.28
Confronting the next influenza pandemic with anti-inflammatory and immunomodulatory agents: why they are needed and how they might work. Influenza Other Respir Viruses (2009) 1.26
Genome-wide mRNA expression analysis of hepatic adaptation to high-fat diets reveals switch from an inflammatory to steatotic transcriptional program. PLoS One (2009) 1.24
PPARγ is an E3 ligase that induces the degradation of NFκB/p65. Nat Commun (2012) 1.23
Inflammation and fibrogenesis in steatohepatitis. J Gastroenterol (2012) 1.21
Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver. J Clin Invest (2015) 1.19
PPARγ activation normalizes resolution of acute sterile inflammation in murine chronic granulomatous disease. Blood (2010) 1.18
The peroxisome proliferator-activated receptor gamma agonist rosiglitazone ameliorates murine lupus by induction of adiponectin. J Immunol (2009) 1.17
Liver X receptor and peroxisome proliferator-activated receptor as integrators of lipid homeostasis and immunity. Immunol Rev (2012) 1.15
Targeting PPAR receptors in the airway for the treatment of inflammatory lung disease. Br J Pharmacol (2009) 1.13
The role of T cell PPAR gamma in mice with experimental inflammatory bowel disease. BMC Gastroenterol (2010) 1.10
Targeting the PIAS1 SUMO ligase pathway to control inflammation. Trends Pharmacol Sci (2008) 1.10
Innate immunity and monocyte-macrophage activation in atherosclerosis. J Inflamm (Lond) (2011) 1.07
PPARs and lipid ligands in inflammation and metabolism. Chem Rev (2011) 1.06
Cerebral malaria: we have come a long way. Am J Pathol (2012) 1.04
Conjugated linoleic acid-mediated inflammation and insulin resistance in human adipocytes are attenuated by resveratrol. J Lipid Res (2008) 1.02
Resolution of inflammation: a new therapeutic frontier. Nat Rev Drug Discov (2016) 1.02
PPARgamma regulates trophoblast proliferation and promotes labyrinthine trilineage differentiation. PLoS One (2009) 1.01
Differential effects of high and low steroidogenic factor-1 expression on CYP11B2 expression and aldosterone production in adrenocortical cells. Endocrinology (2008) 0.99
Peroxisome proliferator-activated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunity. J Exp Med (2010) 0.99
Reduced peroxisome proliferator-activated receptor α expression is associated with decreased survival and increased tissue bacterial load in sepsis. Shock (2012) 0.99
Transcriptional regulation of T helper 17 cell differentiation. Yonsei Med J (2010) 0.98
Inhibition of TLR4-induced IκB kinase activity by the RON receptor tyrosine kinase and its ligand, macrophage-stimulating protein. J Immunol (2010) 0.97
PPARgamma and LXR signaling inhibit dendritic cell-mediated HIV-1 capture and trans-infection. PLoS Pathog (2010) 0.97
Lipids derived from virulent Francisella tularensis broadly inhibit pulmonary inflammation via toll-like receptor 2 and peroxisome proliferator-activated receptor α. Clin Vaccine Immunol (2013) 0.97
Carbon Nanotubes and Chronic Granulomatous Disease. Nanomaterials (Basel) (2014) 0.97
Peroxisome proliferator-activated receptor-gamma ligands induce heme oxygenase-1 in lung fibroblasts by a PPARgamma-independent, glutathione-dependent mechanism. Am J Physiol Lung Cell Mol Physiol (2009) 0.96
Docosahexaenoic acid prevents dendritic cell maturation and in vitro and in vivo expression of the IL-12 cytokine family. Lipids Health Dis (2010) 0.96
Molecular cross-regulation between PPAR-γ and other signaling pathways: implications for lung cancer therapy. Lung Cancer (2011) 0.96
Peroxisome proliferator-activated receptor gamma ligands enhance human B cell antibody production and differentiation. J Immunol (2009) 0.95
The molecular pathways underlying host resistance and tolerance to pathogens. Front Genet (2012) 0.95
Peroxisome proliferator-activated receptor (PPAR)gamma can inhibit chronic renal allograft damage. Am J Pathol (2010) 0.95
PPAR signaling pathway and cancer-related proteins are involved in celiac disease-associated tissue damage. Mol Med (2010) 0.94
Pioglitazone restores phagocyte mitochondrial oxidants and bactericidal capacity in chronic granulomatous disease. J Allergy Clin Immunol (2014) 0.94
Transcription analysis on response of swine lung to H1N1 swine influenza virus. BMC Genomics (2011) 0.93
Cytokine signaling modulates blood-brain barrier function. Curr Pharm Des (2011) 0.92
DNA damage triggers a chronic autoinflammatory response, leading to fat depletion in NER progeria. Cell Metab (2013) 0.92
The plant-based immunomodulator curcumin as a potential candidate for the development of an adjunctive therapy for cerebral malaria. Malar J (2011) 0.91
Palmitoylethanolamide is a disease-modifying agent in peripheral neuropathy: pain relief and neuroprotection share a PPAR-alpha-mediated mechanism. Mediators Inflamm (2013) 0.90
Treatment of vascular risk factors in patients with a diagnosis of Alzheimer's disease: a systematic review. BMC Med (2014) 0.90
GW501516, a PPARδ agonist, ameliorates tubulointerstitial inflammation in proteinuric kidney disease via inhibition of TAK1-NFκB pathway in mice. PLoS One (2011) 0.89
Molecular regulation of tumor angiogenesis and perfusion via redox signaling. Chem Rev (2009) 0.89
T cell PPARγ is required for the anti-inflammatory efficacy of abscisic acid against experimental IBD. J Nutr Biochem (2010) 0.89
Novel mechanisms of endothelial mechanotransduction. Arterioscler Thromb Vasc Biol (2014) 0.89
Serum lipids regulate dendritic cell CD1 expression and function. Immunology (2008) 0.88
Obesity: New life for antidiabetic drugs. Nature (2010) 0.88
Association of PPARgamma allelic variation, osteoprotegerin and abdominal aortic aneurysm. Clin Endocrinol (Oxf) (2009) 0.87
Pioglitazone, a PPARγ agonist, suppresses CYP19 transcription: evidence for involvement of 15-hydroxyprostaglandin dehydrogenase and BRCA1. Cancer Prev Res (Phila) (2012) 0.87
PPAR-gamma: Therapeutic Potential for Multiple Sclerosis. PPAR Res (2008) 0.86
A pilot study of circulating PPAR-γ receptor protein in elderly patients with atrial fibrillation. Arch Med Sci (2012) 0.85
Do PPAR-Gamma Agonists Have a Future in Parkinson's Disease Therapy? Parkinsons Dis (2011) 0.85
Peroxisome proliferator-activated receptor gamma agonists in the prevention and treatment of murine systemic lupus erythematosus. Immunology (2014) 0.85
Lack of PPARγ in myeloid cells confers resistance to Listeria monocytogenes infection. PLoS One (2012) 0.85
Peroxisome proliferator-activated receptor (PPAR): balance for survival in parasitic infections. J Biomed Biotechnol (2010) 0.84
Peroxisome proliferator-activated receptors γ/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus. J Neuroinflammation (2012) 0.84
The role of PPARγ in carbon nanotube-elicited granulomatous lung inflammation. Respir Res (2013) 0.84
Microarray analysis of the intestinal host response in Giardia duodenalis assemblage E infected calves. PLoS One (2012) 0.84
PPARγ as a Potential Target to Treat Airway Mucus Hypersecretion in Chronic Airway Inflammatory Diseases. PPAR Res (2012) 0.84
Opposing roles for mammary epithelial-specific PPARγ signaling and activation during breast tumour progression. Mol Cancer (2015) 0.83
Role of peroxisome proliferator-activated receptor gamma and its ligands in the treatment of hematological malignancies. PPAR Res (2008) 0.83
Peroxisome proliferator-activated receptor gamma is required for CD4+ T cell-mediated lymphopenia-associated autoimmunity. J Immunol (2011) 0.83
PPAR activation induces M1 macrophage polarization via cPLA₂-COX-2 inhibition, activating ROS production against Leishmania mexicana. Biomed Res Int (2013) 0.83
Virus-induced differential expression of nuclear receptors and coregulators in dendritic cells: implication to interferon production. FEBS Lett (2011) 0.83
Sequestration of fatty acids in triglycerides prevents endoplasmic reticulum stress in an in vitro model of cardiomyocyte lipotoxicity. Biochim Biophys Acta (2014) 0.83
PPARgamma Inhibitors as Novel Tubulin-Targeting Agents. PPAR Res (2008) 0.83
Macrophages, PPARs, and Cancer. PPAR Res (2008) 0.83
RhoA mediates defective stem cell function and heterotopic ossification in dystrophic muscle of mice. FASEB J (2013) 0.83
NKG2D receptor regulates human effector T-cell cytokine production. Blood (2011) 0.82
5, 8, 11, 14-eicosatetraynoic acid suppresses CCL2/MCP-1 expression in IFN-γ-stimulated astrocytes by increasing MAPK phosphatase-1 mRNA stability. J Neuroinflammation (2012) 0.82
Rosiglitazone and AS601245 decrease cell adhesion and migration through modulation of specific gene expression in human colon cancer cells. PLoS One (2012) 0.82
Dietary abscisic acid ameliorates influenza-virus-associated disease and pulmonary immunopathology through a PPARγ-dependent mechanism. J Nutr Biochem (2012) 0.82
Modulation of hepatic PPAR expression during Ft LVS LPS-induced protection from Francisella tularensis LVS infection. BMC Infect Dis (2010) 0.82
Macrophage PPARγ and impaired wound healing in type 2 diabetes. J Pathol (2015) 0.82
ARTD1-induced poly-ADP-ribose formation enhances PPARγ ligand binding and co-factor exchange. Nucleic Acids Res (2014) 0.82
Carbon monoxide induced PPARγ SUMOylation and UCP2 block inflammatory gene expression in macrophages. PLoS One (2011) 0.81
Peroxisome proliferator activating receptor (PPAR) in cerebral malaria (CM): a novel target for an additional therapy. Eur J Clin Microbiol Infect Dis (2010) 0.81
A subclass of acylated anti-inflammatory mediators usurp Toll-like receptor 2 to inhibit neutrophil recruitment through peroxisome proliferator-activated receptor gamma. Proc Natl Acad Sci U S A (2011) 0.81
Small heterodimer partner-targeting therapy inhibits systemic inflammatory responses through mitochondrial uncoupling protein 2. PLoS One (2013) 0.81
Effect of prostaglandin I2 analogs on cytokine expression in human myeloid dendritic cells via epigenetic regulation. Mol Med (2012) 0.81
Microglial phenotypes in Parkinson's disease and animal models of the disease. Prog Neurobiol (2016) 0.80
Kinase-SUMO networks in diabetes-mediated cardiovascular disease. Metabolism (2016) 0.80
Carbon nanotube-induced pulmonary granulomatous disease: Twist1 and alveolar macrophage M1 activation. Int J Mol Sci (2013) 0.80
Extension of the neuroprotective time window for thiazolidinediones in ischemic stroke is dependent on time of reperfusion. Neuroscience (2010) 0.80
The ω3-polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A(2) and suppress PGE(2) formation in mesangial cells. Br J Pharmacol (2012) 0.80
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell (2010) 23.97
Macrophages, inflammation, and insulin resistance. Annu Rev Physiol (2010) 11.77
Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription. Nature (2008) 7.18
A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma. Nature (2005) 6.83
A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription. Science (2006) 6.71
A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. J Biol Chem (2007) 6.58
A comprehensive classification system for lipids. J Lipid Res (2005) 6.52
Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. Genes Dev (2006) 6.32
LMSD: LIPID MAPS structure database. Nucleic Acids Res (2006) 6.21
Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA. Nature (2011) 6.10
Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer. Cell (2009) 5.74
Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein. Cell (2002) 5.15
Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones. J Clin Invest (2007) 4.86
A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell (2009) 4.60
A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors. Cell (2004) 4.39
Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma. Mol Cell (2007) 4.33
SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron. Nature (2007) 4.33
A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate. Nat Immunol (2010) 4.32
Concern Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules. Proc Natl Acad Sci U S A (2008) 4.31
Molecular determinants of crosstalk between nuclear receptors and toll-like receptors. Cell (2005) 4.30
Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β. Nature (2012) 4.15
Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature (2007) 4.12
An ADIOL-ERβ-CtBP transrepression pathway negatively regulates microglia-mediated inflammation. Cell (2011) 4.04
Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation. Nature (2013) 3.93
Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis. Proc Natl Acad Sci U S A (2012) 3.90
Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. Nature (2003) 3.72
Direct isolation and identification of promoters in the human genome. Genome Res (2005) 3.68
Anti-inflammatory therapy in chronic disease: challenges and opportunities. Science (2013) 3.64
Expression analysis of G Protein-Coupled Receptors in mouse macrophages. Immunome Res (2008) 3.54
International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors. Pharmacol Rev (2006) 3.48
Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development. Cell (2002) 3.37
Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. Nature (2009) 3.36
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. Nature (2013) 3.33
Deconstructing repression: evolving models of co-repressor action. Nat Rev Genet (2010) 3.29
Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma. J Clin Invest (2004) 3.23
Microglial cell origin and phenotypes in health and disease. Nat Rev Immunol (2011) 3.20
Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation. Mol Cell (2008) 3.18
Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway. Cell (2006) 3.12
Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux. Mol Cell Biol (2002) 3.02
The macrophage foam cell as a target for therapeutic intervention. Nat Med (2002) 2.98
PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression. Nature (2010) 2.91
Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4. J Lipid Res (2006) 2.85
Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis. Science (2007) 2.70
A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation. Proc Natl Acad Sci U S A (2004) 2.56
Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription. Mol Cell (2013) 2.55
Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways. Genes Dev (2009) 2.47
PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages. Proc Natl Acad Sci U S A (2003) 2.40
Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses. Cell (2012) 2.38
TH2 cytokines and allergic challenge induce Ym1 expression in macrophages by a STAT6-dependent mechanism. J Biol Chem (2002) 2.35
Nuclear receptor coregulators: multiple modes of modification. Trends Endocrinol Metab (2002) 2.33
Statins enhance formation of phagocyte extracellular traps. Cell Host Microbe (2010) 2.28
Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosis. Proc Natl Acad Sci U S A (2004) 2.18
Sensitive ChIP-DSL technology reveals an extensive estrogen receptor alpha-binding program on human gene promoters. Proc Natl Acad Sci U S A (2007) 2.17
Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate. Nat Immunol (2012) 2.16
A mouse macrophage lipidome. J Biol Chem (2010) 2.14
Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression. Mol Cell Biol (2003) 2.10
PPARs and molecular mechanisms of transrepression. Biochim Biophys Acta (2007) 2.10
A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation. Mol Cell (2007) 1.98
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. Immunity (2012) 1.96
Evidence mandating earlier and more aggressive treatment of hypercholesterolemia. Circulation (2008) 1.91
Non-coding RNAs as regulators of gene expression and epigenetics. Cardiovasc Res (2011) 1.85
Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation. Mol Cell Biol (2010) 1.75
Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Nature (2011) 1.74
Conserved role for autophagy in Rho1-mediated cortical remodeling and blood cell recruitment. Proc Natl Acad Sci U S A (2010) 1.71
PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis. J Lipid Res (2004) 1.70
Regulated subset of G1 growth-control genes in response to derepression by the Wnt pathway. Proc Natl Acad Sci U S A (2003) 1.68
Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic progenitors. Immunity (2011) 1.66
TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints. Mol Cell (2008) 1.65
MOZ-TIF2-induced acute myeloid leukemia requires the MOZ nucleosome binding motif and TIF2-mediated recruitment of CBP. Cancer Cell (2003) 1.65
Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint. Mol Cell (2009) 1.64
An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation. Cell (2002) 1.63
FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages. EMBO J (2010) 1.60
Maternal hypercholesterolemia during pregnancy promotes early atherogenesis in LDL receptor-deficient mice and alters aortic gene expression determined by microarray. Circulation (2002) 1.58
Mechanisms establishing TLR4-responsive activation states of inflammatory response genes. PLoS Genet (2011) 1.58
Nuclear receptors versus inflammation: mechanisms of transrepression. Trends Endocrinol Metab (2006) 1.57
Efficient regulation of VEGF expression by promoter-targeted lentiviral shRNAs based on epigenetic mechanism: a novel example of epigenetherapy. Circ Res (2009) 1.55
Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Mol Endocrinol (2009) 1.49
Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors. J Immunol (2002) 1.44
The long arm of long noncoding RNAs: roles as sensors regulating gene transcriptional programs. Cold Spring Harb Perspect Biol (2011) 1.43
Sterols and oxysterols in immune cell function. Nat Immunol (2013) 1.41
Roles of peroxisome proliferator-activated receptor gamma in lipid homeostasis and inflammatory responses of macrophages. Curr Opin Lipidol (2002) 1.36
Pharmacological correction of a defect in PPAR-gamma signaling ameliorates disease severity in Cftr-deficient mice. Nat Med (2010) 1.36
Decoding transcriptional programs regulated by PPARs and LXRs in the macrophage: effects on lipid homeostasis, inflammation, and atherosclerosis. Arterioscler Thromb Vasc Biol (2003) 1.33
Regulation of macrophage function in inflammation and atherosclerosis. J Lipid Res (2008) 1.32
Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20. Mol Cell (2012) 1.29
Kdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagy. J Biol Chem (2010) 1.29
Retracted Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules. Cell (2008) 1.27
Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate. Proc Natl Acad Sci U S A (2012) 1.24
Migration of fibrocytes in fibrogenic liver injury. Am J Pathol (2011) 1.17
PE-1/METS, an antiproliferative Ets repressor factor, is induced by CREB-1/CREM-1 during macrophage differentiation. J Biol Chem (2004) 1.17
Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter. BMC Mol Biol (2006) 1.15
Serum response factor utilizes distinct promoter- and enhancer-based mechanisms to regulate cytoskeletal gene expression in macrophages. Mol Cell Biol (2010) 1.15
The type I interferon signaling pathway is a target for glucocorticoid inhibition. Mol Cell Biol (2010) 1.14
Regulation of microglia activation and deactivation by nuclear receptors. Glia (2012) 1.13
Retinoid X receptor alpha controls innate inflammatory responses through the up-regulation of chemokine expression. Proc Natl Acad Sci U S A (2010) 1.13
Macrophages, oxysterols and atherosclerosis. Circ J (2010) 1.13
Nuclear receptors and inflammation control: molecular mechanisms and pathophysiological relevance. Arterioscler Thromb Vasc Biol (2010) 1.11