Published in Front Biosci on January 01, 2008
Cardiac fibroblast: the renaissance cell. Circ Res (2009) 4.01
NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis. Proc Natl Acad Sci U S A (2010) 2.36
S6 kinase 1 knockout inhibits uninephrectomy- or diabetes-induced renal hypertrophy. Am J Physiol Renal Physiol (2009) 1.74
In search of new therapeutic targets and strategies for heart failure: recent advances in basic science. Lancet (2011) 1.69
Glycogen synthase kinase 3 (GSK3) in the heart: a point of integration in hypertrophic signalling and a therapeutic target? A critical analysis. Br J Pharmacol (2008) 1.67
Insulin-like growth factor 1 alleviates high-fat diet-induced myocardial contractile dysfunction: role of insulin signaling and mitochondrial function. Hypertension (2012) 1.66
Redox signaling in cardiac myocytes. Free Radic Biol Med (2011) 1.62
Physiological activation of Akt by PHLPP1 deletion protects against pathological hypertrophy. Cardiovasc Res (2014) 1.46
Deep RNA sequencing reveals novel cardiac transcriptomic signatures for physiological and pathological hypertrophy. PLoS One (2012) 1.24
Transcriptional profile of isoproterenol-induced cardiomyopathy and comparison to exercise-induced cardiac hypertrophy and human cardiac failure. BMC Physiol (2009) 1.20
Myostatin represses physiological hypertrophy of the heart and excitation-contraction coupling. J Physiol (2009) 1.19
The adult heart responds to increased workload with physiologic hypertrophy, cardiac stem cell activation, and new myocyte formation. Eur Heart J (2012) 1.16
From tissue mechanics to transcription factors. Differentiation (2013) 1.16
Akt increases sarcoplasmic reticulum Ca2+ cycling by direct phosphorylation of phospholamban at Thr17. J Biol Chem (2009) 1.09
The Role of MicroRNAs in Human Diseases. Avicenna J Med Biotechnol (2010) 1.04
Cardiac overexpression of insulin-like growth factor 1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction but not hypertrophy: Roles of Akt, mTOR, GSK3beta, and PTEN. Free Radic Biol Med (2010) 1.01
Endocrine actions of myostatin: systemic regulation of the IGF and IGF binding protein axis. Endocrinology (2010) 0.93
Temporal alterations in cardiac fibroblast function following induction of pressure overload. Cell Tissue Res (2010) 0.90
Genome-wide expression patterns in physiological cardiac hypertrophy. BMC Genomics (2010) 0.89
Signaling responses after exposure to 5 alpha-dihydrotestosterone or 17 beta-estradiol in norepinephrine-induced hypertrophy of neonatal rat ventricular myocytes. J Appl Physiol (1985) (2009) 0.86
Normal lactational environment restores cardiomyocyte number after uteroplacental insufficiency: implications for the preterm neonate. Am J Physiol Regul Integr Comp Physiol (2012) 0.85
Neuronal nitric oxide synthase is indispensable for the cardiac adaptive effects of exercise. Basic Res Cardiol (2013) 0.84
The role of TGFβ1 and LRG1 in cardiac remodelling and heart failure. Biophys Rev (2015) 0.83
In vivo key role of reactive oxygen species and NHE-1 activation in determining excessive cardiac hypertrophy. Pflugers Arch (2011) 0.82
ERBB2 deficiency alters an E2F-1-dependent adaptive stress response and leads to cardiac dysfunction. Mol Cell Biol (2014) 0.80
Extracellular matrix-mediated cellular communication in the heart. J Mol Cell Cardiol (2016) 0.78
Mechanosensing and Regulation of Cardiac Function. J Clin Exp Cardiolog (2014) 0.78
Pik3ip1 modulates cardiac hypertrophy by inhibiting PI3K pathway. PLoS One (2015) 0.78
Effects of miRNA-455 on cardiac hypertrophy induced by pressure overload. Int J Mol Med (2015) 0.77
High AU content: a signature of upregulated miRNA in cardiac diseases. Bioinformation (2010) 0.76
Serum IGF-I and hormonal responses to incremental exercise in athletes with and without left ventricular hypertrophy. J Sports Sci Med (2009) 0.75
Differential and conditional activation of PKC-isoforms dictates cardiac adaptation during physiological to pathological hypertrophy. PLoS One (2014) 0.75
Loss of Mouse P2Y6 Nucleotide Receptor Is Associated with Physiological Macrocardia and Amplified Pathological Cardiac Hypertrophy. J Biol Chem (2016) 0.75
Effect of exercise training and myocardial infarction on force development and contractile kinetics in isolated canine myocardium. J Appl Physiol (1985) (2016) 0.75
MicroRNA-133 controls cardiac hypertrophy. Nat Med (2007) 11.68
Isolation and expansion of adult cardiac stem cells from human and murine heart. Circ Res (2004) 8.41
Adult c-kit(pos) cardiac stem cells are necessary and sufficient for functional cardiac regeneration and repair. Cell (2013) 4.99
Cardiovascular risk factors emerge after artificial selection for low aerobic capacity. Science (2005) 4.76
ErbB2 is essential in the prevention of dilated cardiomyopathy. Nat Med (2002) 3.36
Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice. Proc Natl Acad Sci U S A (2002) 3.18
MicroRNAs and cardiac pathology. Nat Rev Cardiol (2009) 2.50
Emerging role of microRNAs in cardiovascular biology. Circ Res (2007) 2.41
MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts. Circ Res (2009) 2.40
Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study. Rejuvenation Res (2009) 2.24
CaMK4 Gene Deletion Induces Hypertension. J Am Heart Assoc (2012) 2.14
Relation of various plasma growth factor levels in patients with stable angina pectoris and total occlusion of a coronary artery to the degree of coronary collaterals. Am J Cardiol (2005) 2.14
Routine assessment of on-clopidogrel platelet reactivity and gene polymorphisms in predicting clinical outcome following drug-eluting stent implantation in patients with stable coronary artery disease. JACC Cardiovasc Interv (2013) 2.11
Akt mediates the cross-talk between beta-adrenergic and insulin receptors in neonatal cardiomyocytes. Circ Res (2004) 2.08
MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. J Clin Invest (2010) 2.04
Deregulation of microRNA-503 contributes to diabetes mellitus-induced impairment of endothelial function and reparative angiogenesis after limb ischemia. Circulation (2011) 1.99
Reciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions. Circulation (2009) 1.92
IkappaB kinase epsilon and TANK-binding kinase 1 activate AKT by direct phosphorylation. Proc Natl Acad Sci U S A (2011) 1.87
MicroRNAs: components of an integrated system controlling cardiac development, physiology, and disease pathogenesis. Cardiovasc Res (2008) 1.75
MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling. Nat Cell Biol (2010) 1.74
Translating cardioprotection for patient benefit: position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology. Cardiovasc Res (2013) 1.72
MicroRNA-133 controls vascular smooth muscle cell phenotypic switch in vitro and vascular remodeling in vivo. Circ Res (2011) 1.67
MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro. J Cell Biol (2010) 1.64
Direct intramyocardial percutaneous delivery of autologous bone marrow in patients with refractory myocardial angina. Am Heart J (2006) 1.59
Rheb is a critical regulator of autophagy during myocardial ischemia: pathophysiological implications in obesity and metabolic syndrome. Circulation (2012) 1.56
MiR-143/145 deficiency attenuates the progression of atherosclerosis in Ldlr-/-mice. Thromb Haemost (2014) 1.53
Nephrotoxicity of low-osmolality versus iso-osmolality contrast agents: impact of N-acetylcysteine. Kidney Int (2005) 1.52
Activation or inactivation of cardiac Akt/mTOR signaling diverges physiological from pathological hypertrophy. J Cell Physiol (2008) 1.48
SOCS1 gene transfer accelerates the transition to heart failure through the inhibition of the gp130/JAK/STAT pathway. Cardiovasc Res (2012) 1.48
Mechanism of enhanced cardiac function in mice with hypertrophy induced by overexpressed Akt. J Biol Chem (2003) 1.47
TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives. J Hypertens (2015) 1.43
Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail (2011) 1.40
Intrinsic aerobic capacity sets a divide for aging and longevity. Circ Res (2011) 1.33
MicroRNA and cardiac pathologies. Physiol Genomics (2008) 1.32
Interval training normalizes cardiomyocyte function, diastolic Ca2+ control, and SR Ca2+ release synchronicity in a mouse model of diabetic cardiomyopathy. Circ Res (2009) 1.29
Akt regulates L-type Ca2+ channel activity by modulating Cavalpha1 protein stability. J Cell Biol (2009) 1.28
microRNAs in heart disease: putative novel therapeutic targets? Eur Heart J (2010) 1.27
Transplantation of low dose CD34+KDR+ cells promotes vascular and muscular regeneration in ischemic limbs. FASEB J (2004) 1.27
Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure. Cardiovasc Res (2008) 1.26
Running speed and maximal oxygen uptake in rats and mice: practical implications for exercise training. Eur J Cardiovasc Prev Rehabil (2007) 1.22
Circulating microRNAs and aerobic fitness--the HUNT-Study. PLoS One (2013) 1.20
MicroRNAs in cardiovascular biology and heart disease. Circ Cardiovasc Genet (2009) 1.19
Regulation of cell size and contractile function by AKT in cardiomyocytes. Ann N Y Acad Sci (2004) 1.19
Induced pluripotent stem cell-derived cardiomyocytes in studies of inherited arrhythmias. J Clin Invest (2013) 1.17
Association study on long-living individuals from Southern Italy identifies rs10491334 in the CAMKIV gene that regulates survival proteins. Rejuvenation Res (2011) 1.17
Akt/protein kinase B and endothelial nitric oxide synthase mediate muscular neovascularization induced by tissue kallikrein gene transfer. Circulation (2004) 1.15
AKT participates in endothelial dysfunction in hypertension. Circulation (2004) 1.15
Time-course of endothelial adaptation following acute and regular exercise. Eur J Cardiovasc Prev Rehabil (2006) 1.14
Myocardial sarcoplasmic reticulum Ca2+ ATPase function is increased by aerobic interval training. Eur J Cardiovasc Prev Rehabil (2008) 1.13
Genome-wide analysis of histone marks identifying an epigenetic signature of promoters and enhancers underlying cardiac hypertrophy. Proc Natl Acad Sci U S A (2013) 1.13
Correlations between progression of coronary artery disease and circulating endothelial progenitor cells. FASEB J (2010) 1.10
Akt increases sarcoplasmic reticulum Ca2+ cycling by direct phosphorylation of phospholamban at Thr17. J Biol Chem (2009) 1.09
Heart infarct in NOD-SCID mice: therapeutic vasculogenesis by transplantation of human CD34+ cells and low dose CD34+KDR+ cells. FASEB J (2004) 1.09
MicroRNAs control gene expression: importance for cardiac development and pathophysiology. Ann N Y Acad Sci (2008) 1.09
Aerobic interval training enhances cardiomyocyte contractility and Ca2+ cycling by phosphorylation of CaMKII and Thr-17 of phospholamban. J Mol Cell Cardiol (2007) 1.08
MiR-133a regulates collagen 1A1: potential role of miR-133a in myocardial fibrosis in angiotensin II-dependent hypertension. J Cell Physiol (2012) 1.07
Long noncoding RNA: a new player of heart failure? J Cardiovasc Transl Res (2013) 1.05
The effect of exercise training on transverse tubules in normal, remodeled, and reverse remodeled hearts. J Cell Physiol (2011) 1.05
Age and gender differences of endothelial function in 4739 healthy adults: the HUNT3 Fitness Study. Eur J Prev Cardiol (2012) 1.03
MicroRNA-134 as a potential plasma biomarker for the diagnosis of acute pulmonary embolism. J Transl Med (2011) 1.01
Doubly heterozygous LMNA and TTN mutations revealed by exome sequencing in a severe form of dilated cardiomyopathy. Eur J Hum Genet (2013) 1.00
c-Myc oncoprotein: cell cycle-related events and new therapeutic challenges in cancer and cardiovascular diseases. Cell Cycle (2003) 1.00
Cardiotoxic effects, or lack thereof, of anti-ErbB2 immunoagents. FASEB J (2009) 0.95
Opposing roles of Akt and STAT3 in the protection of the maternal heart from peripartum stress. Cardiovasc Res (2014) 0.95
Effects of Akt on cardiac myocytes: location counts. Circ Res (2006) 0.94
Molecular determinants of the physiological adaptation to stress in the cardiomyocyte: a focus on AKT. J Mol Cell Cardiol (2004) 0.94
Epigenetics: a new mechanism of regulation of heart failure? Basic Res Cardiol (2013) 0.94
Th1 and Th2 cytokines exert regulatory effects upon islet microvascular areas in the NOD mouse. J Cell Biochem (2002) 0.94
Efficacy and age-related effects of nitric oxide-releasing aspirin on experimental restenosis. Proc Natl Acad Sci U S A (2002) 0.93
Aetiology-specific patterns in end-stage heart failure patients identified by functional annotation and classification of microarray data. Eur J Heart Fail (2006) 0.93
Fatty acid percentage in erythrocyte membranes of atrial flutter/fibrillation patients and controls. J Interv Card Electrophysiol (2010) 0.93
Circulating microRNAs as potential biomarkers of coronary artery disease: a promise to be fulfilled? Circ Res (2010) 0.93
microRNAs in hypertrophy and heart failure. Exp Biol Med (Maywood) (2011) 0.92
Stem cell therapy in heart diseases: a review of selected new perspectives, practical considerations and clinical applications. Curr Cardiol Rev (2011) 0.91
Assessment of the 9p21.3 locus in severity of coronary artery disease in the presence and absence of type 2 diabetes. BMC Med Genet (2013) 0.90
Exercise-induced changes in calcium handling in left ventricular cardiomyocytes. Front Biosci (2008) 0.90
MicroRNA-1 downregulation increases connexin 43 displacement and induces ventricular tachyarrhythmias in rodent hypertrophic hearts. PLoS One (2013) 0.89
Role of microRNAs in haemopoiesis, heart hypertrophy and cancer. Biochem Soc Trans (2008) 0.89
TNF-alpha signal transduction in rat neonatal cardiac myocytes: definition of pathways generating from the TNF-alpha receptor. FASEB J (2002) 0.88
RNA silencing: small RNA-mediated posttranscriptional regulation of mRNA and the implications for heart electropathophysiology. J Cardiovasc Electrophysiol (2008) 0.87
Exercise training restores aerobic capacity and energy transfer systems in heart failure treated with losartan. Cardiovasc Res (2007) 0.86
Reliable resequencing of the human dystrophin locus by universal long polymerase chain reaction and massive pyrosequencing. Anal Biochem (2010) 0.85
Unexpectedly low mutation rates in beta-myosin heavy chain and cardiac myosin binding protein genes in Italian patients with hypertrophic cardiomyopathy. J Cell Physiol (2011) 0.85
Exercise training corrects control of spontaneous calcium waves in hearts from myocardial infarction heart failure rats. J Cell Physiol (2012) 0.85
Human embryonic stem cell-derived cardiomyocytes: inducing strategies. Regen Med (2006) 0.84
Effects of cariporide and losartan on hypertrophy, calcium transients, contractility, and gene expression in congestive heart failure. Circulation (2002) 0.84