Published in Eur Heart J on January 29, 2010
Paracrine mechanisms of stem cell reparative and regenerative actions in the heart. J Mol Cell Cardiol (2010) 1.95
RISC RNA sequencing for context-specific identification of in vivo microRNA targets. Circ Res (2010) 1.66
Methodological challenges in utilizing miRNAs as circulating biomarkers. J Cell Mol Med (2014) 1.34
Induced pluripotent stem cells in cardiovascular drug discovery. Circ Res (2013) 1.22
Regulation of cardiac microRNAs by cardiac microRNAs. Circ Res (2013) 1.15
MicroRNAs in cardiac disease. Transl Res (2011) 1.13
MicroRNA let-7 establishes expression of beta2-adrenergic receptors and dynamically down-regulates agonist-promoted down-regulation. Proc Natl Acad Sci U S A (2011) 1.10
Circulating miR-30a, miR-195 and let-7b associated with acute myocardial infarction. PLoS One (2012) 1.03
BAF60 A, B, and Cs of muscle determination and renewal. Genes Dev (2012) 1.01
Ambient pollutants, polymorphisms associated with microRNA processing and adhesion molecules: the Normative Aging Study. Environ Health (2011) 1.00
Bone marrow mesenchymal stem cells for post-myocardial infarction cardiac repair: microRNAs as novel regulators. J Cell Mol Med (2012) 0.99
Mitochondria and Oxidative Stress in the Cardiorenal Metabolic Syndrome. Cardiorenal Med (2012) 0.98
MicroRNA-15a/b are up-regulated in response to myocardial ischemia/reperfusion injury. J Geriatr Cardiol (2012) 0.98
Cardiovascular microRNAs: as modulators and diagnostic biomarkers of diabetic heart disease. Cardiovasc Diabetol (2014) 0.96
Temporal analysis of mRNA and miRNA expression in transgenic mice overexpressing Arg- and Gly389 polymorphic variants of the β1-adrenergic receptor. Physiol Genomics (2011) 0.95
MicroRNAs and lipoproteins: a connection beyond atherosclerosis? Atherosclerosis (2012) 0.90
Restriction of big hearts by a small RNA. Circ Res (2011) 0.87
MicroRNAs: redefining mechanisms in cardiac disease. J Cardiovasc Pharmacol (2010) 0.87
Cardiac insulin resistance and microRNA modulators. Exp Diabetes Res (2011) 0.84
Atrial fibrillation alters the microRNA expression profiles of the left atria of patients with mitral stenosis. BMC Cardiovasc Disord (2014) 0.83
Menage a Trois: intimate relationship among a microRNA, long noncoding RNA, and mRNA. Circ Res (2014) 0.82
Transcriptome microRNA profiling of bovine mammary glands infected with Staphylococcus aureus. Int J Mol Sci (2015) 0.82
Novel concepts in HDL pharmacology. Cardiovasc Res (2014) 0.80
LIPCAR: a mitochondrial lnc in the noncoding RNA chain? Circ Res (2014) 0.79
Biological significance of miR-126 expression in atrial fibrillation and heart failure. Braz J Med Biol Res (2015) 0.78
Cardiac biomarkers in the intensive care unit. Ann Intensive Care (2012) 0.77
The expanding GRK interactome: Implications in cardiovascular disease and potential for therapeutic development. Pharmacol Res (2016) 0.75
The H3K9 dimethyltransferases EHMT1/2 protect against pathological cardiac hypertrophy. J Clin Invest (2016) 0.75
Calcific Aortic Valve Disease: Part 2-Morphomechanical Abnormalities, Gene Reexpression, and Gender Effects on Ventricular Hypertrophy and Its Reversibility. J Cardiovasc Transl Res (2016) 0.75
Role of microRNA in diabetic cardiomyopathy: From mechanism to intervention. Biochim Biophys Acta (2017) 0.75
Targeting EZH1 and EZH2 contributes to the suppression of fibrosis-associated genes by miR-214-3p in cardiac myofibroblasts. Oncotarget (2016) 0.75
Activation of miR-34a-5p/Sirt1/p66shc pathway contributes to doxorubicin-induced cardiotoxicity. Sci Rep (2017) 0.75
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59
MicroRNAs: target recognition and regulatory functions. Cell (2009) 92.17
MicroRNA expression profiles classify human cancers. Nature (2005) 69.12
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell (1993) 64.62
miRBase: tools for microRNA genomics. Nucleic Acids Res (2007) 38.61
The nuclear RNase III Drosha initiates microRNA processing. Nature (2003) 35.49
Identification of tissue-specific microRNAs from mouse. Curr Biol (2002) 34.55
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell (1993) 33.79
Silencing of microRNAs in vivo with 'antagomirs'. Nature (2005) 32.56
The impact of microRNAs on protein output. Nature (2008) 32.39
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet (2008) 32.08
Widespread changes in protein synthesis induced by microRNAs. Nature (2008) 31.44
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science (2001) 31.33
Origins and Mechanisms of miRNAs and siRNAs. Cell (2009) 20.77
Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol (2009) 19.99
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev (2003) 17.64
Switching from repression to activation: microRNAs can up-regulate translation. Science (2007) 17.00
Dicer is essential for mouse development. Nat Genet (2003) 15.87
MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat Methods (2007) 13.94
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell (2007) 12.72
Control of stress-dependent cardiac growth and gene expression by a microRNA. Science (2007) 12.08
MicroRNA-133 controls cardiac hypertrophy. Nat Med (2007) 11.68
Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA (2004) 11.52
microRNA target predictions in animals. Nat Genet (2006) 10.76
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature (2008) 10.73
Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice. Proc Natl Acad Sci U S A (2006) 10.65
miR-145 and miR-143 regulate smooth muscle cell fate and plasticity. Nature (2009) 10.26
A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proc Natl Acad Sci U S A (2006) 10.09
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci U S A (2008) 9.86
Intronic microRNA precursors that bypass Drosha processing. Nature (2007) 9.65
Argonaute proteins: key players in RNA silencing. Nat Rev Mol Cell Biol (2008) 8.96
The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell (2007) 7.70
Widespread translational inhibition by plant miRNAs and siRNAs. Science (2008) 7.51
The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis. Dev Cell (2008) 7.26
Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs. Genes Dev (2008) 7.07
RNA polymerase III transcribes human microRNAs. Nat Struct Mol Biol (2006) 6.81
miR-126 regulates angiogenic signaling and vascular integrity. Dev Cell (2008) 6.59
MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation. Mol Cell (2008) 6.58
MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure. Circulation (2007) 6.41
AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2. Cell (2007) 5.87
Mammalian mirtron genes. Mol Cell (2007) 5.75
MicroRNAs play an essential role in the development of cardiac hypertrophy. Circ Res (2007) 5.65
Altered microRNA expression in human heart disease. Physiol Genomics (2007) 5.64
microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. Genes Dev (2008) 5.39
Strategies for silencing human disease using RNA interference. Nat Rev Genet (2007) 5.19
A biochemical approach to identifying microRNA targets. Proc Natl Acad Sci U S A (2007) 5.16
MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice. Science (2009) 5.07
Dicer dependent microRNAs regulate gene expression and functions in human endothelial cells. Circ Res (2007) 4.72
MicroRNAs are aberrantly expressed in hypertrophic heart: do they play a role in cardiac hypertrophy? Am J Pathol (2007) 4.65
MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury. Genes Dev (2009) 4.62
A human, ATP-independent, RISC assembly machine fueled by pre-miRNA. Genes Dev (2005) 4.55
Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis. RNA (2004) 4.50
MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest (2009) 4.39
Revisiting the principles of microRNA target recognition and mode of action. Nat Rev Mol Cell Biol (2009) 4.38
MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation. Circ Res (2009) 4.25
microRNA-122 stimulates translation of hepatitis C virus RNA. EMBO J (2008) 4.24
MicroRNA-directed transcriptional gene silencing in mammalian cells. Proc Natl Acad Sci U S A (2008) 4.16
Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster. J Clin Invest (2009) 4.12
Retracted The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes. J Cell Sci (2007) 4.09
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A (2008) 4.00
miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling. Circ Res (2008) 3.96
Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy. J Mol Cell Cardiol (2007) 3.67
The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease. Cell Death Differ (2009) 3.43
MicroRNAs: novel regulators in cardiac development and disease. Cardiovasc Res (2008) 3.30
Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response. FASEB J (1991) 3.29
MicroRNA-320 is involved in the regulation of cardiac ischemia/reperfusion injury by targeting heat-shock protein 20. Circulation (2009) 3.19
MicroRNA-21 protects against the H(2)O(2)-induced injury on cardiac myocytes via its target gene PDCD4. J Mol Cell Cardiol (2009) 3.19
MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths. Mol Biol Cell (2008) 3.10
Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis. Proc Natl Acad Sci U S A (2008) 3.03
Conditional dicer gene deletion in the postnatal myocardium provokes spontaneous cardiac remodeling. Circulation (2008) 2.95
Reciprocal regulation of myocardial microRNAs and messenger RNA in human cardiomyopathy and reversal of the microRNA signature by biomechanical support. Circulation (2009) 2.70
Cloning and expression of new microRNAs from zebrafish. Nucleic Acids Res (2006) 2.58
Experimental validation of miRNA targets. Methods (2008) 2.57
Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure. Circ Res (2009) 2.44
miRNA expression in the failing human heart: functional correlates. J Mol Cell Cardiol (2008) 2.42
MicroRNA regulation of cardiovascular development. Circ Res (2009) 2.42
The GW182 protein family in animal cells: new insights into domains required for miRNA-mediated gene silencing. RNA (2009) 2.37
miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy. Proc Natl Acad Sci U S A (2009) 2.33
Phenotyping hypertrophy: eschew obfuscation. Circ Res (2003) 2.32
MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol (2009) 2.18
MicroRNA-1 regulates cardiomyocyte apoptosis by targeting Bcl-2. Int Heart J (2009) 2.01
Reciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions. Circulation (2009) 1.92
miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2. Circ Res (2009) 1.91
MicroRNAs make big impression in disease after disease. Science (2008) 1.67
Retracted Novel approaches for gene-specific interference via manipulating actions of microRNAs: examination on the pacemaker channel genes HCN2 and HCN4. J Cell Physiol (2007) 1.59
Multifaceted mammalian transcriptome. Curr Opin Cell Biol (2008) 1.52
Retracted Unique microRNA profile in end-stage heart failure indicates alterations in specific cardiovascular signaling networks. J Biol Chem (2009) 1.33
MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes. Biochem Biophys Res Commun (2009) 1.31
A single anti-microRNA antisense oligodeoxyribonucleotide (AMO) targeting multiple microRNAs offers an improved approach for microRNA interference. Nucleic Acids Res (2009) 1.23
MicroRNAs in diseases and drug response. Curr Opin Pharmacol (2008) 1.23
Computational challenges in miRNA target predictions: to be or not to be a true target? J Biomed Biotechnol (2009) 1.14
Changes in regulatory microRNA expression in myocardium of heart failure patients on left ventricular assist device support. J Heart Lung Transplant (2008) 1.03
Genomics, transcriptional profiling, and heart failure. J Am Coll Cardiol (2009) 0.98
Put your chips on transcriptomics. Circulation (2008) 0.93
RNA silencing: small RNA-mediated posttranscriptional regulation of mRNA and the implications for heart electropathophysiology. J Cardiovasc Electrophysiol (2008) 0.87
Cardiac dissonance without conductors: how dicer depletion provokes chaos in the heart. Circulation (2008) 0.84
MiRNA-21: a key to controlling the cardiac fibroblast compartment? Cardiovasc Res (2009) 0.80
MicroRNA-133 controls cardiac hypertrophy. Nat Med (2007) 11.68
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature (2005) 11.22
Isolation and expansion of adult cardiac stem cells from human and murine heart. Circ Res (2004) 8.41
Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling. Circ Res (2007) 4.53
A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure. Nat Med (2008) 3.98
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria. Science (2013) 3.60
Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice. Proc Natl Acad Sci U S A (2002) 3.18
Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure. Circ Res (2011) 2.99
Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming. J Biol Chem (2010) 2.93
Beta 1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure. Nat Med (2003) 2.83
RAS point mutations and PAX8-PPAR gamma rearrangement in thyroid tumors: evidence for distinct molecular pathways in thyroid follicular carcinoma. J Clin Endocrinol Metab (2003) 2.72
Reciprocal regulation of myocardial microRNAs and messenger RNA in human cardiomyopathy and reversal of the microRNA signature by biomechanical support. Circulation (2009) 2.70
Inhibition of cardiac myocyte apoptosis improves cardiac function and abolishes mortality in the peripartum cardiomyopathy of Galpha(q) transgenic mice. Circulation (2003) 2.70
Cardiac myosin-binding protein-C phosphorylation and cardiac function. Circ Res (2005) 2.67
Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human. J Clin Invest (2003) 2.56
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet (2012) 2.53
MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts. Circ Res (2009) 2.40
Phenotyping hypertrophy: eschew obfuscation. Circ Res (2003) 2.32
MiR-15 family regulates postnatal mitotic arrest of cardiomyocytes. Circ Res (2011) 2.32
Mitochondrial fusion is essential for organelle function and cardiac homeostasis. Circ Res (2011) 2.27
Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice. J Clin Invest (2007) 2.23
G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure. Circ Res (2008) 2.22
Nix-mediated apoptosis links myocardial fibrosis, cardiac remodeling, and hypertrophy decompensation. Circulation (2008) 2.21
An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice. J Clin Invest (2008) 2.19
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet (2010) 2.15
Routine assessment of on-clopidogrel platelet reactivity and gene polymorphisms in predicting clinical outcome following drug-eluting stent implantation in patients with stable coronary artery disease. JACC Cardiovasc Interv (2013) 2.11
Cardiac-specific ablation of G-protein receptor kinase 2 redefines its roles in heart development and beta-adrenergic signaling. Circ Res (2006) 2.08
Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy. Nat Med (2002) 2.05
A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy. Proc Natl Acad Sci U S A (2006) 2.05
MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. J Clin Invest (2010) 2.04
Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis. Proc Natl Acad Sci U S A (2007) 1.86
Transforming growth factor beta in cardiovascular development and function. Cytokine Growth Factor Rev (2003) 1.84
Bax regulates primary necrosis through mitochondrial dynamics. Proc Natl Acad Sci U S A (2012) 1.80
Direct and indirect involvement of microRNA-499 in clinical and experimental cardiomyopathy. Circ Res (2012) 1.79
Decompensation of cardiac hypertrophy: cellular mechanisms and novel therapeutic targets. Physiology (Bethesda) (2007) 1.78
Pharmacological- and gene therapy-based inhibition of protein kinase Calpha/beta enhances cardiac contractility and attenuates heart failure. Circulation (2006) 1.73
Mitofusin 2-containing mitochondrial-reticular microdomains direct rapid cardiomyocyte bioenergetic responses via interorganelle Ca(2+) crosstalk. Circ Res (2012) 1.72
RISC RNA sequencing for context-specific identification of in vivo microRNA targets. Circ Res (2010) 1.66
Endoplasmic reticulum-mitochondria crosstalk in NIX-mediated murine cell death. J Clin Invest (2008) 1.65
Proapoptotic effects of caspase-1/interleukin-converting enzyme dominate in myocardial ischemia. Circ Res (2005) 1.64
Deep mRNA sequencing for in vivo functional analysis of cardiac transcriptional regulators: application to Galphaq. Circ Res (2010) 1.61
Additive protection of the ischemic heart ex vivo by combined treatment with delta-protein kinase C inhibitor and epsilon-protein kinase C activator. Circulation (2003) 1.60
Protein kinase Calpha negatively regulates systolic and diastolic function in pathological hypertrophy. Circ Res (2003) 1.58
Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy. Proc Natl Acad Sci U S A (2010) 1.54
Cardiac G-protein-coupled receptor kinase 2 ablation induces a novel Ca2+ handling phenotype resistant to adverse alterations and remodeling after myocardial infarction. Circulation (2012) 1.52
Common variants in HSPB7 and FRMD4B associated with advanced heart failure. Circ Cardiovasc Genet (2010) 1.51
Sarcoplasmic reticulum calcium overloading in junctin deficiency enhances cardiac contractility but increases ventricular automaticity. Circulation (2007) 1.51
Distinct pathways regulate proapoptotic Nix and BNip3 in cardiac stress. J Biol Chem (2005) 1.48
Mediating ERK 1/2 signaling rescues congenital heart defects in a mouse model of Noonan syndrome. J Clin Invest (2007) 1.48
Novel and nondetected human signaling protein polymorphisms. Physiol Genomics (2002) 1.44
Clinical and genetic modifiers of long-term survival in heart failure. J Am Coll Cardiol (2009) 1.42
GRK2-dependent S1PR1 desensitization is required for lymphocytes to overcome their attraction to blood. Science (2011) 1.40
Inhibition of apoptosis-regulated signaling kinase-1 and prevention of congestive heart failure by estrogen. Circulation (2007) 1.39
Mitochondrial fusion directs cardiomyocyte differentiation via calcineurin and Notch signaling. Science (2013) 1.39
Physiological myocardial hypertrophy: how and why? Front Biosci (2008) 1.35
Physiological growth synergizes with pathological genes in experimental cardiomyopathy. Circ Res (2004) 1.34
Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy. J Clin Invest (2003) 1.33
Loss-of-function DNA sequence variant in the CLCNKA chloride channel implicates the cardio-renal axis in interindividual heart failure risk variation. Proc Natl Acad Sci U S A (2011) 1.33
Reduction of sympathetic activity via adrenal-targeted GRK2 gene deletion attenuates heart failure progression and improves cardiac function after myocardial infarction. J Biol Chem (2010) 1.32
Protein kinase D links Gq-coupled receptors to cAMP response element-binding protein (CREB)-Ser133 phosphorylation in the heart. J Biol Chem (2008) 1.29
Regulation of cardiac contractility by Rab4-modulated beta2-adrenergic receptor recycling. Proc Natl Acad Sci U S A (2004) 1.28
Histidine-rich Ca binding protein: a regulator of sarcoplasmic reticulum calcium sequestration and cardiac function. J Mol Cell Cardiol (2006) 1.26
Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure. Cardiovasc Res (2008) 1.26
G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia. Circulation (2011) 1.23
Cardiomyocyte degeneration with calpain deficiency reveals a critical role in protein homeostasis. Circ Res (2007) 1.23
Epitranscriptional orchestration of genetic reprogramming is an emergent property of stress-regulated cardiac microRNAs. Proc Natl Acad Sci U S A (2012) 1.20
Microglial/macrophage GRK2 determines duration of peripheral IL-1beta-induced hyperalgesia: contribution of spinal cord CX3CR1, p38 and IL-1 signaling. Pain (2010) 1.17
The Ser96Ala variant in histidine-rich calcium-binding protein is associated with life-threatening ventricular arrhythmias in idiopathic dilated cardiomyopathy. Eur Heart J (2008) 1.17
BNip3 regulates mitochondrial function and lipid metabolism in the liver. Mol Cell Biol (2012) 1.17
Molecular MRI detects low levels of cardiomyocyte apoptosis in a transgenic model of chronic heart failure. Circ Cardiovasc Imaging (2009) 1.16
GRK2: a novel cell-specific regulator of severity and duration of inflammatory pain. J Neurosci (2010) 1.15
Regulation of cardiac microRNAs by cardiac microRNAs. Circ Res (2013) 1.15
Polymorphisms of the beta1-adrenergic receptor predict exercise capacity in heart failure. Am Heart J (2002) 1.14
Mitochondrial contagion induced by Parkin deficiency in Drosophila hearts and its containment by suppressing mitofusin. Circ Res (2013) 1.13
Genome-wide analysis of histone marks identifying an epigenetic signature of promoters and enhancers underlying cardiac hypertrophy. Proc Natl Acad Sci U S A (2013) 1.13
RhoA protects the mouse heart against ischemia/reperfusion injury. J Clin Invest (2011) 1.12
Targeting cyclophilin D and the mitochondrial permeability transition enhances beta-cell survival and prevents diabetes in Pdx1 deficiency. Proc Natl Acad Sci U S A (2010) 1.12
Nuclear effects of G-protein receptor kinase 5 on histone deacetylase 5-regulated gene transcription in heart failure. Circ Heart Fail (2011) 1.12
Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease. J Clin Invest (2009) 1.10
Mitochondrial localization unveils a novel role for GRK2 in organelle biogenesis. Cell Signal (2011) 1.10
Akt increases sarcoplasmic reticulum Ca2+ cycling by direct phosphorylation of phospholamban at Thr17. J Biol Chem (2009) 1.09
MicroRNAs control gene expression: importance for cardiac development and pathophysiology. Ann N Y Acad Sci (2008) 1.09
Abnormal neurodevelopment, neurosignaling and behaviour in Npas3-deficient mice. Eur J Neurosci (2005) 1.09
Cardiac-specific overexpression of catalase identifies hydrogen peroxide-dependent and -independent phases of myocardial remodeling and prevents the progression to overt heart failure in G(alpha)q-overexpressing transgenic mice. Circ Heart Fail (2009) 1.09
Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report. Am J Respir Crit Care Med (2010) 1.09
Akt-mediated cardiomyocyte survival pathways are compromised by G alpha q-induced phosphoinositide 4,5-bisphosphate depletion. J Biol Chem (2003) 1.05
Long noncoding RNA: a new player of heart failure? J Cardiovasc Transl Res (2013) 1.05
Myeloid-specific GPCR kinase-2 negatively regulates NF-κB1p105-ERK pathway and limits endotoxemic shock in mice. J Cell Physiol (2011) 1.05
Loss of Nix in Pdx1-deficient mice prevents apoptotic and necrotic β cell death and diabetes. J Clin Invest (2010) 1.02
Cell-specific roles of GRK2 in onset and severity of hypoxic-ischemic brain damage in neonatal mice. Brain Behav Immun (2009) 1.01
Gi-biased β2AR signaling links GRK2 upregulation to heart failure. Circ Res (2011) 1.01
Myocardial Ablation of G Protein-Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic Pathway. PLoS One (2013) 1.00
Receptor-independent protein kinase C alpha (PKCalpha) signaling by calpain-generated free catalytic domains induces HDAC5 nuclear export and regulates cardiac transcription. J Biol Chem (2011) 1.00
Ca2+ dysregulation induces mitochondrial depolarization and apoptosis: role of Na+/Ca2+ exchanger and AKT. J Biol Chem (2005) 1.00
Cardiac miR-133a overexpression prevents early cardiac fibrosis in diabetes. J Cell Mol Med (2014) 1.00
Receptor-independent cardiac protein kinase Calpha activation by calpain-mediated truncation of regulatory domains. Circ Res (2010) 1.00
The presence of Lys27 instead of Asn27 in human phospholamban promotes sarcoplasmic reticulum Ca2+-ATPase superinhibition and cardiac remodeling. Circulation (2006) 1.00
MicroRNA-155 tunes both the threshold and extent of NK cell activation via targeting of multiple signaling pathways. J Immunol (2013) 0.98
Fatty acid synthase modulates homeostatic responses to myocardial stress. J Biol Chem (2011) 0.98