Published in Eukaryot Cell on November 09, 2007
Efflux-mediated antifungal drug resistance. Clin Microbiol Rev (2009) 2.44
Statistical inference of the time-varying structure of gene-regulation networks. BMC Syst Biol (2010) 1.22
Structure and properties of transcriptional networks driving selenite stress response in yeasts. BMC Genomics (2008) 1.07
Genome adaptation to chemical stress: clues from comparative transcriptomics in Saccharomyces cerevisiae and Candida glabrata. Genome Biol (2008) 1.02
Calcineurin signaling and membrane lipid homeostasis regulates iron mediated multidrug resistance mechanisms in Candida albicans. PLoS One (2011) 1.00
Inference of sparse combinatorial-control networks from gene-expression data: a message passing approach. BMC Bioinformatics (2010) 0.99
Multidrug resistance in fungi: regulation of transporter-encoding gene expression. Front Physiol (2014) 0.98
Evolutionary divergence in the fungal response to fluconazole revealed by soft clustering. Genome Biol (2010) 0.97
RNA sequencing revealed novel actors of the acquisition of drug resistance in Candida albicans. BMC Genomics (2012) 0.96
In vitro effect of malachite green on Candida albicans involves multiple pathways and transcriptional regulators UPC2 and STP2. Antimicrob Agents Chemother (2011) 0.87
Novel Regulatory Mechanisms of Pathogenicity and Virulence to Combat MDR in Candida albicans. Int J Microbiol (2013) 0.86
Lipidome analysis reveals antifungal polyphenol curcumin affects membrane lipid homeostasis. Front Biosci (Elite Ed) (2012) 0.85
Curcumin targets cell wall integrity via calcineurin-mediated signaling in Candida albicans. Antimicrob Agents Chemother (2013) 0.83
Control of Plasma Membrane Permeability by ABC Transporters. Eukaryot Cell (2015) 0.77
Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A (2001) 132.88
Integrating functional genomic information into the Saccharomyces genome database. Nucleic Acids Res (2000) 18.52
Nosocomial bloodstream infections in United States hospitals: a three-year analysis. Clin Infect Dis (1999) 10.30
Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast. PLoS Biol (2004) 6.38
Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus. Antimicrob Agents Chemother (1997) 5.66
Rewiring of the yeast transcriptional network through the evolution of motif usage. Science (2005) 3.10
T-profiler: scoring the activity of predefined groups of genes using gene expression data. Nucleic Acids Res (2005) 2.88
TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2. Eukaryot Cell (2004) 2.61
Comparative gene expression analysis by differential clustering approach: application to the Candida albicans transcription program. PLoS Genet (2005) 2.36
Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans. Antimicrob Agents Chemother (2005) 2.35
Genome microarray analysis of transcriptional activation in multidrug resistance yeast mutants. FEBS Lett (2000) 2.22
A common drug-responsive element mediates the upregulation of the Candida albicans ABC transporters CDR1 and CDR2, two genes involved in antifungal drug resistance. Mol Microbiol (2002) 2.14
Role of Candida albicans transcription factor Upc2p in drug resistance and sterol metabolism. Eukaryot Cell (2004) 1.87
PDR3, a new yeast regulatory gene, is homologous to PDR1 and controls the multidrug resistance phenomenon. Mol Gen Genet (1994) 1.63
The Candida Genome Database (CGD), a community resource for Candida albicans gene and protein information. Nucleic Acids Res (2005) 1.61
Goulphar: rapid access and expertise for standard two-color microarray normalization methods. BMC Bioinformatics (2006) 1.57
Oxidative stress-activated zinc cluster protein Stb5 has dual activator/repressor functions required for pentose phosphate pathway regulation and NADPH production. Mol Cell Biol (2006) 1.46
Positive autoregulation of the yeast transcription factor Pdr3p, which is involved in control of drug resistance. Mol Cell Biol (1995) 1.45
Genome-wide expression and location analyses of the Candida albicans Tac1p regulon. Eukaryot Cell (2007) 1.35
Genome-wide expression profiling reveals genes associated with amphotericin B and fluconazole resistance in experimentally induced antifungal resistant isolates of Candida albicans. J Antimicrob Chemother (2004) 1.33
Candida albicans estrogen-binding protein gene encodes an oxidoreductase that is inhibited by estradiol. Proc Natl Acad Sci U S A (1994) 1.27
An artificial transcription activator mimics the genome-wide properties of the yeast Pdr1 transcription factor. EMBO Rep (2001) 1.21
Membrane sphingolipid-ergosterol interactions are important determinants of multidrug resistance in Candida albicans. Antimicrob Agents Chemother (2004) 1.20
Transcriptional control of multidrug resistance in the yeast Saccharomyces. Prog Nucleic Acid Res Mol Biol (2003) 1.19
Antagonism of azole activity against Candida albicans following induction of multidrug resistance genes by selected antimicrobial agents. Antimicrob Agents Chemother (1999) 1.12
Complex interplay among regulators of drug resistance genes in Saccharomyces cerevisiae. J Biol Chem (2004) 1.11
The central role of PDR1 in the foundation of yeast drug resistance. J Biol Chem (2006) 1.10
Cloning and expression of the gene from Candida albicans that encodes a high-affinity corticosteroid-binding protein. Proc Natl Acad Sci U S A (1993) 1.06
Genome-wide studies on the nuclear PDR3-controlled response to mitochondrial dysfunction in yeast. FEBS Lett (2002) 1.01
Transcription initiation of genes associated with azole resistance in Candida albicans. Med Mycol (2002) 1.01
Characterisation of human steroid hormone transport mediated by Cdr1p, a multidrug transporter of Candida albicans, belonging to the ATP binding cassette super family. FEMS Microbiol Lett (1998) 1.00
SRE1 and SRE2 are two specific steroid-responsive modules of Candida drug resistance gene 1 (CDR1) promoter. Yeast (2004) 0.99
Membrane raft lipid constituents affect drug susceptibilities of Candida albicans. Biochem Soc Trans (2005) 0.92
Antagonism between two mechanisms of antifungal drug resistance. Eukaryot Cell (2006) 0.89
Cellular and molecular biology of Candida albicans estrogen response. Eukaryot Cell (2006) 0.85
A genome-wide steroid response study of the major human fungal pathogen Candida albicans. Mycopathologia (2007) 0.84
Steroid binding protein(s) in yeasts. Biochem Int (1985) 0.82
Genome-wide expression profile of steroid response in Saccharomyces cerevisiae. Biochem Biophys Res Commun (2004) 0.81
Potent competitive inhibition of drug binding to the Saccharomyces cerevisiae ABC exporter Pdr5p by the hydrophobic estradiol-derivative RU49953. Biochim Biophys Acta (2003) 0.77
AP endonuclease-independent DNA base excision repair in human cells. Mol Cell (2004) 3.37
Population Health Metrics Research Consortium gold standard verbal autopsy validation study: design, implementation, and development of analysis datasets. Popul Health Metr (2011) 3.21
Genome-wide analysis of mRNAs targeted to yeast mitochondria. EMBO Rep (2002) 2.94
Base excision repair intermediates induce p53-independent cytotoxic and genotoxic responses. J Biol Chem (2003) 1.95
Yeast mitochondrial biogenesis: a role for the PUF RNA-binding protein Puf3p in mRNA localization. PLoS One (2008) 1.92
Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage. Mol Cell (2006) 1.79
DNA polymerase lambda mediates a back-up base excision repair activity in extracts of mouse embryonic fibroblasts. J Biol Chem (2005) 1.72
Effects of Hatha yoga and Omkar meditation on cardiorespiratory performance, psychologic profile, and melatonin secretion. J Altern Complement Med (2004) 1.61
Ssu72 is a phosphatase essential for transcription termination of snoRNAs and specific mRNAs in yeast. EMBO J (2003) 1.59
DNA polymerase beta and flap endonuclease 1 enzymatic specificities sustain DNA synthesis for long patch base excision repair. J Biol Chem (2004) 1.59
Comparison of three incisions to repair complete unilateral cleft lip. Plast Reconstr Surg (2010) 1.51
Direct interaction between mammalian DNA polymerase beta and proliferating cell nuclear antigen. J Biol Chem (2002) 1.48
NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells. DNA Repair (Amst) (2006) 1.45
Ammonia pulses and metabolic oscillations guide yeast colony development. Mol Biol Cell (2002) 1.44
Erythropoietin levels in lowlanders and high-altitude natives at 3450 m. Aviat Space Environ Med (2007) 1.42
In Saccharomyces cerevisiae, ATP2 mRNA sorting to the vicinity of mitochondria is essential for respiratory function. EMBO J (2002) 1.41
Functional characterization of Candida albicans ABC transporter Cdr1p. Eukaryot Cell (2003) 1.40
In vitro low-level resistance to azoles in Candida albicans is associated with changes in membrane lipid fluidity and asymmetry. Antimicrob Agents Chemother (2002) 1.38
Recognition of and response to postpartum hemorrhage in rural northern India. J Midwifery Womens Health (2005) 1.38
Coordination between polymerase beta and FEN1 can modulate CAG repeat expansion. J Biol Chem (2009) 1.37
Drug susceptibilities of yeast cells are affected by membrane lipid composition. Antimicrob Agents Chemother (2002) 1.36
Coordination of steps in single-nucleotide base excision repair mediated by apurinic/apyrimidinic endonuclease 1 and DNA polymerase beta. J Biol Chem (2007) 1.34
The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase beta. Nucleic Acids Res (2006) 1.34
Stimulation of NEIL2-mediated oxidized base excision repair via YB-1 interaction during oxidative stress. J Biol Chem (2007) 1.32
Unexpected link between iron and drug resistance of Candida spp.: iron depletion enhances membrane fluidity and drug diffusion, leading to drug-susceptible cells. Antimicrob Agents Chemother (2006) 1.30
Domestication of wild Saccharomyces cerevisiae is accompanied by changes in gene expression and colony morphology. Mol Microbiol (2003) 1.28
yMGV: a cross-species expression data mining tool. Nucleic Acids Res (2004) 1.27
Pathogenicity and drug resistance in Candida albicans and other yeast species. A review. Acta Microbiol Immunol Hung (2007) 1.25
Long mRNAs coding for yeast mitochondrial proteins of prokaryotic origin preferentially localize to the vicinity of mitochondria. Genome Biol (2003) 1.24
Contribution of medical colleges to tuberculosis control in India under the Revised National Tuberculosis Control Programme (RNTCP): lessons learnt & challenges ahead. Indian J Med Res (2013) 1.21
New insights into the pleiotropic drug resistance network from genome-wide characterization of the YRR1 transcription factor regulation system. Mol Cell Biol (2002) 1.20
Activities and mechanism of DNA polymerase beta. Methods Enzymol (2006) 1.20
High-level expression and purification of untagged and histidine-tagged HIV-1 reverse transcriptase. Protein Expr Purif (2004) 1.20
Complete inventory of ABC proteins in human pathogenic yeast, Candida albicans. J Mol Microbiol Biotechnol (2005) 1.20
Membrane sphingolipid-ergosterol interactions are important determinants of multidrug resistance in Candida albicans. Antimicrob Agents Chemother (2004) 1.20
The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity. J Biol Chem (2003) 1.19
AP endonuclease and poly(ADP-ribose) polymerase-1 interact with the same base excision repair intermediate. DNA Repair (Amst) (2004) 1.19
Human base excision repair enzymes apurinic/apyrimidinic endonuclease1 (APE1), DNA polymerase beta and poly(ADP-ribose) polymerase 1: interplay between strand-displacement DNA synthesis and proofreading exonuclease activity. Nucleic Acids Res (2005) 1.16
Interplay between DNA polymerases beta and lambda in repair of oxidation DNA damage in chicken DT40 cells. DNA Repair (Amst) (2007) 1.14
Development of bilateral chylothorax in a younger female secondary to tuberculosis. Lung India (2011) 1.13
Hemoglobin receptor in Leishmania is a hexokinase located in the flagellar pocket. J Biol Chem (2004) 1.12
Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts. Antimicrob Agents Chemother (2007) 1.12
A general strategy to uncover transcription factor properties identifies a new regulator of drug resistance in yeast. J Biol Chem (2003) 1.11
Identification of small molecule synthetic inhibitors of DNA polymerase beta by NMR chemical shift mapping. J Biol Chem (2004) 1.11
The central role of PDR1 in the foundation of yeast drug resistance. J Biol Chem (2006) 1.10
Incidence of cleft Lip and palate in the state of Andhra Pradesh, South India. Indian J Plast Surg (2010) 1.10
Functional analysis of CaIPT1, a sphingolipid biosynthetic gene involved in multidrug resistance and morphogenesis of Candida albicans. Antimicrob Agents Chemother (2005) 1.09
Structure and function analysis of CaMdr1p, a major facilitator superfamily antifungal efflux transporter protein of Candida albicans: identification of amino acid residues critical for drug/H+ transport. Eukaryot Cell (2007) 1.09
Mutagenic conformation of 8-oxo-7,8-dihydro-2'-dGTP in the confines of a DNA polymerase active site. Nat Struct Mol Biol (2010) 1.08
Ady2p is essential for the acetate permease activity in the yeast Saccharomyces cerevisiae. Yeast (2004) 1.08
HMGB1: roles in base excision repair and related function. Biochim Biophys Acta (2010) 1.07
yMGV: helping biologists with yeast microarray data mining. Nucleic Acids Res (2002) 1.07
Structure and properties of transcriptional networks driving selenite stress response in yeasts. BMC Genomics (2008) 1.07
Multi-drug resistant tuberculosis: an iatrogenic problem. Biosci Trends (2010) 1.07
Physicians' knowledge regarding the recommended anti-tuberculosis prescribed medication regimen: a cross-sectional survey from Lucknow, India. Southeast Asian J Trop Med Public Health (2008) 1.06
Susceptibility pattern and molecular type of species-specific Candida in oropharyngeal lesions of Indian human immunodeficiency virus-positive patients. J Clin Microbiol (2004) 1.05
Hydronephrosis due to pelviureteric junction narrowing: Utility of urinary enzymes to predict the need for surgical management and follow-up. J Indian Assoc Pediatr Surg (2012) 1.05
Sok2p transcription factor is involved in adaptive program relevant for long term survival of Saccharomyces cerevisiae colonies. J Biol Chem (2004) 1.05
Adverse drug reactions to antiretroviral therapy (ART): an experience of spontaneous reporting and intensive monitoring from ART centre in India. Pharmacoepidemiol Drug Saf (2010) 1.05
DNA polymerase beta-dependent long patch base excision repair in living cells. DNA Repair (Amst) (2009) 1.05
MFS transportome of the human pathogenic yeast Candida albicans. BMC Genomics (2008) 1.04
Purification and characterization of the N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: uncommon cysteine 193 of Walker A is critical for ATP hydrolysis. Biochemistry (2003) 1.04
Competitive promoter occupancy by two yeast paralogous transcription factors controlling the multidrug resistance phenomenon. J Biol Chem (2003) 1.03
Down-regulation of DNA polymerase beta accompanies somatic hypermutation in human BL2 cell lines. DNA Repair (Amst) (2006) 1.03
Characterization of Cdr1p, a major multidrug efflux protein of Candida albicans: purified protein is amenable to intrinsic fluorescence analysis. Biochemistry (2006) 1.03
Pulmonary mucormycosis mimicking as pulmonary tuberculosis: a case report. Lung India (2008) 1.03
Genome adaptation to chemical stress: clues from comparative transcriptomics in Saccharomyces cerevisiae and Candida glabrata. Genome Biol (2008) 1.02
Clustering of Fournier (male genital) gangrene cases in a pediatric cancer ward. Med Pediatr Oncol (2003) 1.02
Different structural states in oligonucleosomes are required for early versus late steps of base excision repair. Nucleic Acids Res (2007) 1.02
Genome-wide studies on the nuclear PDR3-controlled response to mitochondrial dysfunction in yeast. FEBS Lett (2002) 1.01
Interactions between bacteria and Candida in the burn wound. Burns (2005) 1.01
Alanine scanning of transmembrane helix 11 of Cdr1p ABC antifungal efflux pump of Candida albicans: identification of amino acid residues critical for drug efflux. J Antimicrob Chemother (2005) 1.01
Identification of a negative regulatory element which regulates basal transcription of a multidrug resistance gene CDR1 of Candida albicans. FEMS Yeast Res (2004) 1.01
Metabolic diversification of cells during the development of yeast colonies. Environ Microbiol (2009) 1.01
Transcriptional regulation by Lge1p requires a function independent of its role in histone H2B ubiquitination. J Biol Chem (2004) 1.01
Synergistic anticandidal activity of pure polyphenol curcumin I in combination with azoles and polyenes generates reactive oxygen species leading to apoptosis. FEMS Yeast Res (2010) 1.01
The domain organization and properties of individual domains of DNA topoisomerase V, a type 1B topoisomerase with DNA repair activities. J Biol Chem (2001) 1.00
Mitochondrial presequence and open reading frame mediate asymmetric localization of messenger RNA. EMBO Rep (2010) 1.00
The pattern of the maxillofacial fractures - A multicentre retrospective study. J Craniomaxillofac Surg (2011) 1.00
Calcineurin signaling and membrane lipid homeostasis regulates iron mediated multidrug resistance mechanisms in Candida albicans. PLoS One (2011) 1.00
Dosage-dependent functions of fatty acid desaturase Ole1p in growth and morphogenesis of Candida albicans. Microbiology (2004) 0.99
Study of serum calcium and trace elements in chronic cholelithiasis. ANZ J Surg (2002) 0.99
SRE1 and SRE2 are two specific steroid-responsive modules of Candida drug resistance gene 1 (CDR1) promoter. Yeast (2004) 0.99
Squalene epoxidase encoded by ERG1 affects morphogenesis and drug susceptibilities of Candida albicans. J Antimicrob Chemother (2005) 0.98
Antifungal curcumin induces reactive oxygen species and triggers an early apoptosis but prevents hyphae development by targeting the global repressor TUP1 in Candida albicans. Biosci Rep (2010) 0.98
Functional characterization of Helicobacter pylori DnaB helicase. Nucleic Acids Res (2003) 0.97
Spatio-temporal dynamics of yeast mitochondrial biogenesis: transcriptional and post-transcriptional mRNA oscillatory modules. PLoS Comput Biol (2009) 0.96
Prevalence of multidrug resistant Mycobacterium tuberculosis in Lucknow, Uttar Pradesh. Indian J Med Res (2008) 0.96
Structure of DNA polymerase beta with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic features. Proc Natl Acad Sci U S A (2006) 0.96
RNA sequencing revealed novel actors of the acquisition of drug resistance in Candida albicans. BMC Genomics (2012) 0.96
Association of inducible nitric oxide synthase with asthma severity, total serum immunoglobulin E and blood eosinophil levels. Thorax (2007) 0.96