Published in J Mol Biol on October 22, 2007
Immunogenicity of anti-TNF biologic therapies for rheumatoid arthritis. Nat Rev Rheumatol (2013) 1.32
Differential risk of tuberculosis reactivation among anti-TNF therapies is due to drug binding kinetics and permeability. J Immunol (2012) 1.07
Identification of key processes that control tumor necrosis factor availability in a tuberculosis granuloma. PLoS Comput Biol (2010) 1.00
Structural basis for treating tumor necrosis factor α (TNFα)-associated diseases with the therapeutic antibody infliximab. J Biol Chem (2013) 0.99
Immunogenicity to Biotherapeutics - The Role of Anti-drug Immune Complexes. Front Immunol (2016) 0.83
Current approaches to fine mapping of antigen-antibody interactions. Immunology (2014) 0.82
A white paper--consensus and recommendations of a global harmonization team on assessing the impact of immunogenicity on pharmacokinetic measurements. AAPS J (2014) 0.81
Reconfigurable microfluidics with integrated aptasensors for monitoring intercellular communication. Lab Chip (2014) 0.81
Aggregation, immune complexes and immunogenicity. MAbs (2011) 0.80
One target, different effects: a comparison of distinct therapeutic antibodies against the same targets. Exp Mol Med (2011) 0.79
Engineering of a human kringle domain into agonistic and antagonistic binding proteins functioning in vitro and in vivo. Proc Natl Acad Sci U S A (2010) 0.78
Engineering of Immunoglobulin Fc Heterodimers Using Yeast Surface-Displayed Combinatorial Fc Library Screening. PLoS One (2015) 0.76
Affinity Maturation of an Epidermal Growth Factor Receptor Targeting Human Monoclonal Antibody ER414 by CDR Mutation. Immune Netw (2012) 0.76
Posttranslational Modifications and the Immunogenicity of Biotherapeutics. J Immunol Res (2016) 0.76
Therapeutic TNF Inhibitors can Differentially Stabilize Trimeric TNF by Inhibiting Monomer Exchange. Sci Rep (2016) 0.76
Characterization of the complex formed between a potent neutralizing ovine-derived polyclonal anti-TNFα Fab fragment and human TNFα. Biosci Rep (2013) 0.76
Distribution of eschars on the body of scrub typhus patients: a prospective study. Am J Trop Med Hyg (2007) 3.36
Spotted fever group and typhus group rickettsioses in humans, South Korea. Emerg Infect Dis (2005) 2.53
Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus. Arthritis Res Ther (2010) 1.93
Usefulness of nested PCR for the diagnosis of scrub typhus in clinical practice: A prospective study. Am J Trop Med Hyg (2006) 1.57
Identification of the spotted fever group rickettsiae detected from Haemaphysalis longicornis in Korea. Microbiol Immunol (2003) 1.56
Evaluation of PCR-based assay for diagnosis of spotted fever group rickettsiosis in human serum samples. Clin Diagn Lab Immunol (2005) 1.55
Regulating human Th17 cells via differential expression of IL-1 receptor. Blood (2009) 1.54
Expression profiling and subtype-specific expression of stomach cancer. Cancer Res (2003) 1.43
Domain-level antibody epitope mapping through yeast surface display of epidermal growth factor receptor fragments. J Immunol Methods (2004) 1.39
First serologic evidence of human spotted fever group rickettsiosis in Korea. J Clin Microbiol (2004) 1.38
Clinical usefulness of eschar polymerase chain reaction for the diagnosis of scrub typhus: a prospective study. Clin Infect Dis (2006) 1.36
Directed evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity. Proc Natl Acad Sci U S A (2006) 1.32
Application of a weights-of-evidence method and GIS to regional groundwater productivity potential mapping. J Environ Manage (2011) 1.28
Identification of the epitope for the epidermal growth factor receptor-specific monoclonal antibody 806 reveals that it preferentially recognizes an untethered form of the receptor. J Biol Chem (2004) 1.23
Screening and characterization of a novel esterase from a metagenomic library. Protein Expr Purif (2005) 1.22
Multiple large cysts arising from nevus comedonicus. Arch Plast Surg (2012) 1.22
A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells. Cancer Res (2007) 1.19
Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity. J Biol Chem (2006) 1.14
Role of the RAM network in cell polarity and hyphal morphogenesis in Candida albicans. Mol Biol Cell (2008) 1.13
DNA-encoded self-assembly of gold nanoparticles into one-dimensional arrays. Angew Chem Int Ed Engl (2005) 1.11
VDUP1 mediates nuclear export of HIF1alpha via CRM1-dependent pathway. Biochim Biophys Acta (2007) 1.08
Upregulation of Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved in the JNK-mediated autophagic cell death. Biochem Biophys Res Commun (2009) 1.05
Controlled trial of a 5-day course of telithromycin versus doxycycline for treatment of mild to moderate scrub typhus. Antimicrob Agents Chemother (2007) 1.04
A surface plasmon enhanced infrared photodetector based on InAs quantum dots. Nano Lett (2010) 1.01
Molecular detection of various rickettsiae in mites (acari: trombiculidae) in southern Jeolla Province, Korea. Microbiol Immunol (2007) 1.01
High-resolution structure of ybfF from Escherichia coli K12: a unique substrate-binding crevice generated by domain arrangement. J Mol Biol (2008) 1.01
Improved mutants from directed evolution are biased to orthologous substitutions. Protein Eng Des Sel (2006) 1.00
Differentiation of rickettsiae by groEL gene analysis. J Clin Microbiol (2003) 1.00
Sub-10-nm nanochannels by self-sealing and self-limiting atomic layer deposition. Nano Lett (2010) 0.99
Effects of solutes on solubilization and refolding of proteins from inclusion bodies with high hydrostatic pressure. Protein Sci (2005) 0.98
Novel candidate targets of Wnt/beta-catenin signaling in hepatoma cells. Life Sci (2006) 0.98
Gender-dependent hepatic alterations in H-ras12V transgenic mice. J Hepatol (2005) 0.98
High prevalence of RET, RAS, and ERK expression in Hashimoto's thyroiditis and in papillary thyroid carcinoma in the Korean population. Thyroid (2007) 0.98
1,25-Dihyroxyvitamin D3 promotes FOXP3 expression via binding to vitamin D response elements in its conserved noncoding sequence region. J Immunol (2012) 0.97
Identification of the Coxiella sp. detected from Haemaphysalis longicornis ticks in Korea. Microbiol Immunol (2004) 0.97
A DNA nanomachine based on a duplex-triplex transition. Angew Chem Int Ed Engl (2004) 0.97
Work environments and exposure to hazardous substances in korean tire manufacturing. Saf Health Work (2012) 0.95
Tear production and ocular surface changes in experimental dry eye after elimination of desiccating stress. Invest Ophthalmol Vis Sci (2011) 0.94
Therapeutic effect of subconjunctival injection of bevacizumab in the treatment of corneal neovascularization. Acta Ophthalmol (2008) 0.94
Homomeric and heteromeric interactions of the extracellular domains of death receptors and death decoy receptors. Biochem Biophys Res Commun (2005) 0.94
Phylogenetic analysis of the 56 kDa protein genes of Orientia tsutsugamushi in Southwest Area of Korea. Am J Trop Med Hyg (2011) 0.94
DNA as nanoscale building blocks. J Nanosci Nanotechnol (2005) 0.93
High-level production of arachidonic acid by fed-batch culture of Mortierella alpina using NH4OH as a nitrogen source and pH control. Biotechnol Lett (2005) 0.93
Characteristics of Occupational Exposure to Benzene during Turnaround in the Petrochemical Industries. Saf Health Work (2010) 0.93
The association between the vascular endothelial growth factor-to-cancer antigen 125 ratio in peritoneal dialysis effluent and the epithelial-to-mesenchymal transition in continuous ambulatory peritoneal dialysis. Perit Dial Int (2008) 0.91
An agonistic antibody to human death receptor 4 induces apoptotic cell death in head and neck cancer cells through mitochondrial ROS generation. Cancer Lett (2012) 0.91
Rapid and simple identification of Orientia tsutsugamushi from other group rickettsiae by duplex PCR assay using groEL gene. Microbiol Immunol (2005) 0.90
A heterodimeric Fc-based bispecific antibody simultaneously targeting VEGFR-2 and Met exhibits potent antitumor activity. Mol Cancer Ther (2013) 0.90
Effects of switching to long-acting injectable risperidone from oral atypical antipsychotics on cognitive function in patients with schizophrenia. Hum Psychopharmacol (2009) 0.90
Temperature adaptation in Gillichthys (Teleost: Gobiidae) A(4)-lactate dehydrogenases: identical primary structures produce subtly different conformations. J Exp Biol (2002) 0.90
A novel anti-EGFR monoclonal antibody inhibiting tumor cell growth by recognizing different epitopes from cetuximab. J Biotechnol (2010) 0.90
Expression of soluble and functional human neonatal Fc receptor in Pichia pastoris. Protein Expr Purif (2009) 0.90
Sexual dysfunction in male stroke patients: correlation between brain lesions and sexual function. Urology (2008) 0.89
Regulation of glycogen synthase kinase-3 by thymosin beta-4 is associated with gastric cancer cell migration. Int J Cancer (2012) 0.88
Direct observation of quasi-coherent thermal emission by a three-dimensional metallic photonic crystal. Opt Lett (2013) 0.88
Construction and characterization of a pseudo-immune human antibody library using yeast surface display. Biochem Biophys Res Commun (2006) 0.88
Characterization of effector memory CD8+ T cells in the synovial fluid of rheumatoid arthritis. J Clin Immunol (2012) 0.88
Molecular characterization of enteroviruses detected in Gyeong-Ju and Po-Hang provinces of Korea in 2003. Arch Virol (2010) 0.86
Expression of CCR5 and its ligands CCL3, -4, and -5 in the tear film and ocular surface of patients with dry eye disease. Curr Eye Res (2011) 0.86
Enhancement of the tumor penetration of monoclonal antibody by fusion of a neuropilin-targeting peptide improves the antitumor efficacy. Mol Cancer Ther (2014) 0.86
Gene expression profiling: canonical molecular changes and clinicopathological features in sporadic colorectal cancers. World J Gastroenterol (2008) 0.86
Seroepidemiology of spotted fever group and typhus group rickettsioses in humans, South Korea. Microbiol Immunol (2005) 0.86
Acute abdomen caused by an infected mesenteric cyst in the ascending colon: a case report. J Korean Soc Coloproctol (2011) 0.85
A novel agonistic antibody to human death receptor 4 induces apoptotic cell death in various tumor cells without cytotoxicity in hepatocytes. Mol Cancer Ther (2009) 0.85
Characterization of a novel anti-human TNF-alpha murine monoclonal antibody with high binding affinity and neutralizing activity. Exp Mol Med (2008) 0.85
Extensive alteration in the expression profiles of TGFB pathway signaling components and TP53 is observed along the gastric dysplasia-carcinoma sequence. Histol Histopathol (2008) 0.85
Amisulpride versus risperidone in the treatment of depression in patients with schizophrenia: a randomized, open-label, controlled trial. Prog Neuropsychopharmacol Biol Psychiatry (2007) 0.84
Death receptors 4 and 5 activate Nox1 NADPH oxidase through riboflavin kinase to induce reactive oxygen species-mediated apoptotic cell death. J Biol Chem (2011) 0.84
Elucidating interactions and conductivity of newly synthesised low bandgap polymer with protic and aprotic ionic liquids. PLoS One (2013) 0.84
Crystal structure of a minimal nitroreductase, ydjA, from Escherichia coli K12 with and without FMN cofactor. J Mol Biol (2008) 0.84
Design of roll-to-roll printing equipment with multiple printing methods for multi-layer printing. Rev Sci Instrum (2012) 0.84
Fatal systemic infection with multifocal liver and lung nodules caused by Brucella abortus. Am J Trop Med Hyg (2007) 0.84
Involvement of Ca2+/calmodulin kinase II (CaMK II) in genistein-induced potentiation of leucine/glutamine-stimulated insulin secretion. Mol Cells (2009) 0.83
Comparison of chemical compositions and antimicrobial activities of essential oils from three conifer trees; Pinus densiflora, Cryptomeria japonica, and Chamaecyparis obtusa. J Microbiol Biotechnol (2009) 0.83
Histone deacetylase inhibitors synergistically potentiate death receptor 4-mediated apoptotic cell death of human T-cell acute lymphoblastic leukemia cells. Apoptosis (2010) 0.83
Crystal structure of single-domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals. Proteins (2008) 0.83
Diagnosis of scrub typhus by immunohistochemical staining of Orientia tsutsugamushi in cutaneous lesions. Am J Clin Pathol (2008) 0.82
Differentiation of Anaplasmataceae through partial groEL gene analysis. Microbiol Immunol (2005) 0.82
Photodynamic therapy with verteporfin combined with subconjunctival injection of bevacizumab for corneal neovascularization. Cornea (2011) 0.82
Overexpression of CD24: association with invasiveness in urothelial carcinoma of the bladder. Arch Pathol Lab Med (2007) 0.82
Cellular internalization mechanism and intracellular trafficking of filamentous M13 phages displaying a cell-penetrating transbody and TAT peptide. PLoS One (2012) 0.82
Purification and characterization of two polymorphic variants of short chain acyl-CoA dehydrogenase reveal reduction of catalytic activity and stability of the Gly185Ser enzyme. Biochemistry (2002) 0.82
A case of esophageal achalasia compressing left atrium diagnosed by echocardiography in patient with acute chest pain. J Cardiovasc Ultrasound (2012) 0.82
Round-robin test on thermal conductivity measurement of ZnO nanofluids and comparison of experimental results with theoretical bounds. Nanoscale Res Lett (2011) 0.82
Pre-operative predictive factors for gallbladder cholesterol polyps using conventional diagnostic imaging. World J Gastroenterol (2008) 0.82
Efficient and directed Nano-LED emission by a complete elimination of transverse-electric guided modes. Nano Lett (2010) 0.81
First molecular detection of Borrelia afzelii in clinical samples in Korea. Microbiol Immunol (2007) 0.81
Role of Th1 and Th17 cells in the development and complexity of coronary artery disease: comparison analysis by the methods of flow cytometry and SYNTAX score. Coron Artery Dis (2015) 0.80
An RNA-hydrolyzing recombinant antibody exhibits an antiviral activity against classical swine fever virus. Biochem Biophys Res Commun (2010) 0.80
Humanization of an agonistic anti-death receptor 4 single chain variable fragment antibody and avidity-mediated enhancement of its cell death-inducing activity. Mol Immunol (2009) 0.80
Generation of humanized anti-DNA hydrolyzing catalytic antibodies by complementarity determining region grafting. Biochem Biophys Res Commun (2008) 0.80
Gene silencing by cell-penetrating, sequence-selective and nucleic-acid hydrolyzing antibodies. Nucleic Acids Res (2009) 0.80