Gab2 and Src co-operate in human mammary epithelial cells to promote growth factor independence and disruption of acinar morphogenesis.

PubWeight™: 0.99‹?› | Rank: Top 15%

🔗 View Article (PMID 17998934)

Published in Oncogene on November 12, 2007

Authors

H L Bennett1, T Brummer, A Jeanes, A S Yap, R J Daly

Author Affiliations

1: Cancer Research Program, Garvan Institute of Medical Research, Sydney, NSW, Australia.

Articles citing this

Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation. Physiol Rev (2011) 2.06

Kruppel-like factor 4 inhibits epithelial-to-mesenchymal transition through regulation of E-cadherin gene expression. J Biol Chem (2010) 1.79

Function, regulation and pathological roles of the Gab/DOS docking proteins. Cell Commun Signal (2009) 1.59

Gab2-mediated signaling promotes melanoma metastasis. Am J Pathol (2009) 1.21

Gab2 regulates the migratory behaviors and E-cadherin expression via activation of the PI3K pathway in ovarian cancer cells. Oncogene (2011) 1.11

GAB2--a scaffolding protein in cancer. Mol Cancer Res (2012) 1.09

Identification of a Src tyrosine kinase/SIAH2 E3 ubiquitin ligase pathway that regulates C/EBPδ expression and contributes to transformation of breast tumor cells. Mol Cell Biol (2011) 0.97

Cortactin is a functional target of E-cadherin-activated Src family kinases in MCF7 epithelial monolayers. J Biol Chem (2009) 0.95

A novel MCF-10A line allowing conditional oncogene expression in 3D culture. Cell Commun Signal (2011) 0.94

Oncogenic signaling by tyrosine kinases of the SRC family in advanced colorectal cancer. Am J Cancer Res (2012) 0.89

GAB2 induces tumor angiogenesis in NRAS-driven melanoma. Oncogene (2012) 0.89

Gab2 regulates cytoskeletal organization and migration of mammary epithelial cells by modulating RhoA activation. Mol Biol Cell (2010) 0.87

c-Jun N-terminal Kinase 2 Regulates Multiple Receptor Tyrosine Kinase Pathways in Mouse Mammary Tumor Growth and Metastasis. Genes Cancer (2011) 0.86

Alterations of Gab2 signalling complexes in imatinib and dasatinib treated chronic myeloid leukaemia cells. Cell Commun Signal (2013) 0.86

Binding of the cSH3 domain of Grb2 adaptor to two distinct RXXK motifs within Gab1 docker employs differential mechanisms. J Mol Recognit (2010) 0.81

Gab adapter proteins as therapeutic targets for hematologic disease. Adv Hematol (2011) 0.78

Articles by these authors

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling. Cell (1992) 8.20

A new modification of the carbazole analysis: application to heteropolysaccharides. Anal Biochem (1968) 5.56

Recycling of E-cadherin: a potential mechanism for regulating cadherin dynamics. J Cell Biol (1999) 4.89

Cadherins and cancer: how does cadherin dysfunction promote tumor progression? Oncogene (2008) 3.63

Lateral dimerization is required for the homophilic binding activity of C-cadherin. J Cell Biol (1996) 2.95

SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high-affinity binding site for SH2 domains of phospholipase C gamma. EMBO J (1992) 2.82

Colonial variation in Xanthomonas campestris NRRL B-1459 and characterization of the polysaccharide from a variant strain. Can J Microbiol (1976) 1.99

Mood and behavioural changes with progestational agents. Br J Psychiatry (1967) 1.72

The influence of age, gender and ABO blood group on soluble endothelial cell markers and adhesion molecules. Br J Haematol (1996) 1.64

Exposure of Gambian children to Anopheles gambiae malaria vectors in an irrigated rice production area. Med Vet Entomol (1995) 1.62

A dileucine motif targets E-cadherin to the basolateral cell surface in Madin-Darby canine kidney and LLC-PK1 epithelial cells. J Biol Chem (2001) 1.59

Severe invasive Panton-Valentine Leucocidin positive Staphylococcus aureus infections in children in London, UK. J Infect (2009) 1.55

Coal gas and the brain. Br Med J (1968) 1.52

Increased soluble interleukin 2 receptor levels in schizophrenia. Schizophr Res (1998) 1.45

Activation of the Ras signalling pathway in human breast cancer cells overexpressing erbB-2. Oncogene (1994) 1.44

Cleanyourhands Campaign: a critique of the critique. J Hosp Infect (2007) 1.42

Ability of Anopheles gambiae mosquitoes to transmit malaria during the dry and wet seasons in an area of irrigated rice cultivation in The Gambia. J Trop Med Hyg (1991) 1.39

Signaling pathways and structural domains required for phosphorylation of EMS1/cortactin. Cancer Res (1999) 1.39

Increased incidence of Clostridium difficile infection. J Hosp Infect (1997) 1.39

Identification of a novel human tankyrase through its interaction with the adaptor protein Grb14. J Biol Chem (2001) 1.38

Psychosis associated with the use of a sequential oral contraceptive. Lancet (1967) 1.31

Analysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3. J Biol Chem (1998) 1.21

Functional analysis of the regulatory requirements of B-Raf and the B-Raf(V600E) oncoprotein. Oncogene (2006) 1.18

Rational protocols for testing faeces in the investigation of sporadic hospital-acquired diarrhoea. J Hosp Infect (2001) 1.14

Structural determinants of the interaction between the erbB2 receptor and the Src homology 2 domain of Grb7. J Biol Chem (1997) 1.08

EMS1 amplification can occur independently of CCND1 or INT-2 amplification at 11q13 and may identify different phenotypes in primary breast cancer. Oncogene (1997) 1.08

Detection of a nosocomial outbreak of salmonellosis may be delayed by application of a protocol for rejection of stool cultures. J Hosp Infect (2004) 1.08

The ras signaling pathway in mammary tumorigenesis and metastasis. J Mammary Gland Biol Neoplasia (2001) 1.07

Gab2 signaling in chronic myeloid leukemia cells confers resistance to multiple Bcr-Abl inhibitors. Leukemia (2012) 1.06

Impact of rapid molecular screening for meticillin-resistant Staphylococcus aureus in surgical wards. Br J Surg (2008) 1.05

Interpersonal problem-solving skills training in the treatment of self-poisoning patients. Suicide Life Threat Behav (1994) 1.05

EMS1 gene expression in primary breast cancer: relationship to cyclin D1 and oestrogen receptor expression and patient survival. Oncogene (1998) 1.05

Inhibition of the MAP kinase cascade blocks heregulin-induced cell cycle progression in T-47D human breast cancer cells. Oncogene (1998) 1.04

Effects of oestrogen on the expression of a 4.4 kb mRNA in the ZR-75-1 human breast cancer cell line. Mol Cell Endocrinol (1988) 1.02

Immunochemical and related interactions with dextrans reviewed in terms of improved structural information. Mol Immunol (1986) 1.00

Annexin A6 inhibits Ras signalling in breast cancer cells. Oncogene (2008) 1.00

Determination of the composition of uronic acid mixtures. Anal Biochem (1968) 0.99

Up-regulation of the protein tyrosine phosphatase SHP-1 in human breast cancer and correlation with GRB2 expression. Int J Cancer (2000) 0.98

Reaction of sodium hypochlorite with amines and amides. A new method for quantitating polysaccharides containing hexosamines. Anal Biochem (1971) 0.97

Marketing hand hygiene in hospitals--a case study. J Hosp Infect (2002) 0.97

Functional characterization of cancer-associated Gab1 mutations. Oncogene (2012) 0.97

The human GRB2 and Drosophila Drk genes can functionally replace the Caenorhabditis elegans cell signaling gene sem-5. Mol Biol Cell (1993) 0.96

The effects of L-methionine (without MAOI) in schizophrenia. J Psychiatr Res (1971) 0.96

Early communication: does a national campaign to improve hand hygiene in the NHS work? Initial English and Welsh experience from the NOSEC study (National Observational Study to Evaluate the CleanYourHandsCampaign). J Hosp Infect (2007) 0.95

Reaction of sodium hypochlorite with amines and amides: a new method for quantitating amino sugars in monomeric form. Anal Biochem (1971) 0.95

Lupus anticoagulant. Ann Intern Med (1989) 0.93

Annexin A6 is a scaffold for PKCα to promote EGFR inactivation. Oncogene (2012) 0.93

Hostility and chronic intermittent haemodialysis. J Psychosom Res (1969) 0.89

Removing bacteria from hospital surfaces: a laboratory comparison of ultramicrofibre and standard cloths. J Hosp Infect (2008) 0.89

Flying phobia: phobia: phenomenological study. Proc R Soc Med (1970) 0.88

Performance of ultramicrofibre cleaning technology with or without addition of a novel copper-based biocide. J Hosp Infect (2009) 0.87

Eradication of persistent environmental MRSA. J Hosp Infect (2005) 0.86

Expression and tyrosine phosphorylation of EMS1 in human breast cancer cell lines. Int J Cancer (1996) 0.86

Approaches to studying the role of growth factors in the progression of breast tumours from the steroid sensitive to insensitive state. J Steroid Biochem (1989) 0.85

Extracellular polysaccharide from the black yeast NRRL Y-6272: improved methods for preparing a high-viscosity, pigment-free product. Appl Microbiol (1975) 0.85

The antiproliferative effects of progestins in T47D breast cancer cells are tempered by progestin induction of the ETS transcription factor Elf5. Mol Endocrinol (2010) 0.83

Granulosa cell tumors express erbB4 and are sensitive to the cytotoxic action of heregulin-beta2/PE40. Cancer Res (1998) 0.83

Characterization of cell polarity and epithelial junctions in the choriocarcinoma cell line, JAR. Placenta (1995) 0.83

The RhoGAP protein Deleted in Liver Cancer 3 (DLC3) is essential for adherens junctions integrity. Oncogenesis (2012) 0.83

Mianserin in the treatment of depressive illness: a comparison with amitriptyline. Ir J Med Sci (1979) 0.82

Extracellular black yeast polysaccharide composed of N-acetyl glucosamine and N-acetyl glucosaminuronic acid. Nat New Biol (1971) 0.81

Use of first line bronchoalveolar lavage in the immunosuppressed oncology patient. Bone Marrow Transplant (2001) 0.80

Interpersonal problem-solving deficits in self-poisoning patients. Suicide Life Threat Behav (1987) 0.80

Effectiveness of short-term, enhanced, infection control support in improving compliance with infection control guidelines and practice in nursing homes: a cluster randomized trial. Epidemiol Infect (2009) 0.78

Tyrosine kinase signalling in breast cancer: modulation of tyrosine kinase signalling in human breast cancer through altered expression of signalling intermediates. Breast Cancer Res (2000) 0.78

Heregulin (HRG)-induced mitogenic signaling and cytotoxic activity of a HRG/PE40 ligand toxin in human breast cancer cells. Cell Growth Differ (1995) 0.78

Prognostic factors of advanced colorectal cancer patients. Eur J Cancer Clin Oncol (1986) 0.78

Two severe reactions to benzodiazepine compounds. Am J Psychiatry (1965) 0.77

Transition of human breast cancer cells from an oestrogen responsive to unresponsive state. J Steroid Biochem Mol Biol (1990) 0.76

Role of cell-cell contact in the preservation of differentiation and response to thyrotrophin in cultured porcine thyroid cells. J Endocrinol (1987) 0.76

Assignment of the human GRB14 gene to chromosome 2q22-q24 by fluorescence in situ hybridization. Genomics (1996) 0.76

Liaison psychiatry in an Irish hospital: a survey of a year's experience. Gen Hosp Psychiatry (1986) 0.76

Samuel Pepys and post-traumatic stress disorder. Br J Psychiatry (1983) 0.76

Reported sleep on maintenance haemodialysis. Br Med J (1970) 0.76

Handwashing: answering questions and pursuing compliance. J Hosp Infect (2001) 0.75

Treatment of flying phobia in trained aircrew. Proc R Soc Med (1970) 0.75

Hydrogen peroxide vapour decontamination of a critical care unit room used to treat a patient with Lassa fever. J Hosp Infect (2010) 0.75

Response to: Griffith CJ, Dancer SJ. 'Hospital cleaning: problems with steam cleaning and microfibre'. J Hosp Infect (2009) 0.75

Microbiological evaluation of South Australian rock lobster meat. J Hyg (Lond) (1977) 0.75

Amelioration of premenstrual mood disturbance with a progestational agent (enovid). Dis Nerv Syst (1966) 0.75

Multiple endocrine neoplasia type 2b: long-term follow-up of a case. Med J Aust (1990) 0.75

Drugs update. Stopping the drugs trolley. Nurs Times (1992) 0.75

Selective liquid chromatographic assay for propylthiouracil in plasma. J Chromatogr (1991) 0.75

Koro-like syndrome associated with brief reactive psychosis in an Irish male. Ir Med J (1996) 0.75

Different expression of adhesion molecules ICAM-1 and VCAM-1 and activation markers MHC class II and IL-2R in acute and chronic rejection of rat kidney allografts. Transplant Proc (1997) 0.75

Compensation and rehabilitation of victims of torture. An example of preventive psychiatry. Dan Med Bull (1980) 0.75

The after-hours psychiatric emergency. Health Bull (Edinb) (1970) 0.75

Urine volume and pink spots in schizophrenia and health. Nature (1969) 0.75

Some observations concerning the "pink spot" reacting substances in urine. Acta Psychiatr Scand (1970) 0.75

Hyperkalemia associated with diarrhea. Ann Intern Med (1990) 0.75

Draft hand hygiene standards. J Hosp Infect (2001) 0.75

Panic disorder. Ir Med J (1993) 0.75

Endocrine profiles in premenstrual tension. Clin Endocrinol (Oxf) (1972) 0.75

Affect ive disorder taxonomies in middle-aged females. Br J Psychiatry (1968) 0.75

Soluble interleukin 2 receptor levels in acute and stable schizophrenia. Schizophr Res (2001) 0.75

An extracellular fungal polysaccharide composed of 2-acetamido-2-deoxy-D-glucuronic acid residues. Carbohydr Res (1976) 0.75

Treatment of flying phobia in aircrew. Am J Psychother (1971) 0.75

Stress in medical students. Ir Med J (1997) 0.75