PubRank

David S Roos

Author PubWeight™ 239.85‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genome sequence of the human malaria parasite Plasmodium falciparum. Nature 2002 37.89
2 OrthoMCL: identification of ortholog groups for eukaryotic genomes. Genome Res 2003 33.03
3 OrthoMCL-DB: querying a comprehensive multi-species collection of ortholog groups. Nucleic Acids Res 2006 11.43
4 PlasmoDB: a functional genomic database for malaria parasites. Nucleic Acids Res 2008 6.73
5 PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data. Nucleic Acids Res 2003 6.19
6 Assessing performance of orthology detection strategies applied to eukaryotic genomes. PLoS One 2007 5.62
7 Chemical genetics of Plasmodium falciparum. Nature 2010 5.52
8 The Plasmodium genome database. Nature 2002 4.36
9 Creating a honey bee consensus gene set. Genome Biol 2007 4.17
10 ToxoDB: an integrated Toxoplasma gondii database resource. Nucleic Acids Res 2007 3.96
11 Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast. Nat Rev Microbiol 2004 3.85
12 TriTrypDB: a functional genomic resource for the Trypanosomatidae. Nucleic Acids Res 2009 3.79
13 ToxoDB: accessing the Toxoplasma gondii genome. Nucleic Acids Res 2003 3.24
14 Dissecting apicoplast targeting in the malaria parasite Plasmodium falciparum. Science 2003 3.08
15 Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii. Nucleic Acids Res 2005 2.64
16 Genomic-scale prioritization of drug targets: the TDR Targets database. Nat Rev Drug Discov 2008 2.58
17 The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology. Immunity 2012 2.52
18 Cytoskeletal components of an invasion machine--the apical complex of Toxoplasma gondii. PLoS Pathog 2006 2.43
19 ApiDB: integrated resources for the apicomplexan bioinformatics resource center. Nucleic Acids Res 2006 2.37
20 PlasmoDB: the Plasmodium genome resource. An integrated database providing tools for accessing, analyzing and mapping expression and sequence data (both finished and unfinished). Nucleic Acids Res 2002 2.37
21 GiardiaDB and TrichDB: integrated genomic resources for the eukaryotic protist pathogens Giardia lamblia and Trichomonas vaginalis. Nucleic Acids Res 2008 2.35
22 Daughter cell assembly in the protozoan parasite Toxoplasma gondii. Mol Biol Cell 2002 2.19
23 Using OrthoMCL to assign proteins to OrthoMCL-DB groups or to cluster proteomes into new ortholog groups. Curr Protoc Bioinformatics 2011 2.15
24 EuPathDB: a portal to eukaryotic pathogen databases. Nucleic Acids Res 2009 2.11
25 The Plasmodium eukaryotic initiation factor-2alpha kinase IK2 controls the latency of sporozoites in the mosquito salivary glands. J Exp Med 2010 2.08
26 The transcriptome of Toxoplasma gondii. BMC Biol 2005 2.06
27 Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii. Proc Natl Acad Sci U S A 2006 1.95
28 Integrative genomic approaches highlight a family of parasite-specific kinases that regulate host responses. Cell Host Microbe 2010 1.90
29 Apicomplexan parasites co-opt host calpains to facilitate their escape from infected cells. Science 2009 1.77
30 Gene discovery in the apicomplexa as revealed by EST sequencing and assembly of a comparative gene database. Genome Res 2003 1.75
31 Organellar dynamics during the cell cycle of Toxoplasma gondii. J Cell Sci 2008 1.70
32 Golgi biogenesis in Toxoplasma gondii. Nature 2002 1.67
33 A novel polymer of tubulin forms the conoid of Toxoplasma gondii. J Cell Biol 2002 1.56
34 Measuring tubulin content in Toxoplasma gondii: a comparison of laser-scanning confocal and wide-field fluorescence microscopy. Proc Natl Acad Sci U S A 2002 1.55
35 EuPathDB: the eukaryotic pathogen database. Nucleic Acids Res 2012 1.53
36 Functional inactivation of immature dendritic cells by the intracellular parasite Toxoplasma gondii. J Immunol 2004 1.49
37 Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy. PLoS Pathog 2012 1.44
38 Toxoplasma gondii scavenges host-derived lipoic acid despite its de novo synthesis in the apicoplast. EMBO J 2006 1.42
39 Identification of attractive drug targets in neglected-disease pathogens using an in silico approach. PLoS Negl Trop Dis 2010 1.39
40 FungiDB: an integrated functional genomics database for fungi. Nucleic Acids Res 2011 1.37
41 Dynamic Imaging of CD8(+) T cells and dendritic cells during infection with Toxoplasma gondii. PLoS Pathog 2009 1.37
42 Toward community standards in the quest for orthologs. Bioinformatics 2012 1.36
43 The proteome of Toxoplasma gondii: integration with the genome provides novel insights into gene expression and annotation. Genome Biol 2008 1.35
44 ApiEST-DB: analyzing clustered EST data of the apicomplexan parasites. Nucleic Acids Res 2004 1.30
45 Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii. Genome Res 2006 1.28
46 Cytotoxic T cells mediate pathology and metastasis in cutaneous leishmaniasis. PLoS Pathog 2013 1.28
47 Toxoplasma gondii Hsp90 is a potential drug target whose expression and subcellular localization are developmentally regulated. J Mol Biol 2005 1.27
48 Presentation of Toxoplasma gondii antigens via the endogenous major histocompatibility complex class I pathway in nonprofessional and professional antigen-presenting cells. Infect Immun 2007 1.26
49 Dynamics of Toxoplasma gondii differentiation. Eukaryot Cell 2004 1.26
50 Evolutionary constraints on structural similarity in orthologs and paralogs. Protein Sci 2009 1.23
51 A novel multifunctional oligonucleotide microarray for Toxoplasma gondii. BMC Genomics 2010 1.23
52 Secretory traffic in the eukaryotic parasite Toxoplasma gondii: less is more. J Cell Biol 2002 1.22
53 Purine salvage pathways in the apicomplexan parasite Toxoplasma gondii. J Biol Chem 2004 1.21
54 Identification and characterization of differentiation mutants in the protozoan parasite Toxoplasma gondii. Mol Microbiol 2002 1.20
55 TDR Targets: a chemogenomics resource for neglected diseases. Nucleic Acids Res 2011 1.15
56 Transcriptome of axenic liver stages of Plasmodium yoelii. Mol Biochem Parasitol 2004 1.14
57 Golgi and centrosome cycles in Toxoplasma gondii. Mol Biochem Parasitol 2005 1.12
58 Identification of surprisingly diverse type IV pili, across a broad range of gram-positive bacteria. PLoS One 2011 1.11
59 Kinetics and phenotype of vaccine-induced CD8+ T-cell responses to Toxoplasma gondii. Infect Immun 2009 1.10
60 Comparative genomics of the pathogenic ciliate Ichthyophthirius multifiliis, its free-living relatives and a host species provide insights into adoption of a parasitic lifestyle and prospects for disease control. Genome Biol 2011 1.09
61 Protozoan genomics for drug discovery. Nat Biotechnol 2005 1.09
62 A monomorphic haplotype of chromosome Ia is associated with widespread success in clonal and nonclonal populations of Toxoplasma gondii. MBio 2011 1.09
63 AmoebaDB and MicrosporidiaDB: functional genomic resources for Amoebozoa and Microsporidia species. Nucleic Acids Res 2010 1.08
64 Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8+ T cells. J Immunol 2010 1.07
65 Initiation and termination of NF-kappaB signaling by the intracellular protozoan parasite Toxoplasma gondii. J Cell Sci 2005 1.04
66 Fitness effects of DHFR-TS mutations associated with pyrimethamine resistance in apicomplexan parasites. Mol Microbiol 2003 1.04
67 Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways. PLoS One 2011 1.04
68 Variability and heritability of cell division pathways in Toxoplasma gondii. J Cell Sci 2004 1.03
69 PlasmoDB v5: new looks, new genomes. Trends Parasitol 2006 1.03
70 Evigan: a hidden variable model for integrating gene evidence for eukaryotic gene prediction. Bioinformatics 2008 1.01
71 The Strategies WDK: a graphical search interface and web development kit for functional genomics databases. Database (Oxford) 2011 1.01
72 N-terminal positively charged amino acids, but not their exact position, are important for apicoplast transit peptide fidelity in Toxoplasma gondii. Mol Biochem Parasitol 2006 0.96
73 Differential localization of alternatively spliced hypoxanthine-xanthine-guanine phosphoribosyltransferase isoforms in Toxoplasma gondii. J Biol Chem 2005 0.96
74 cDNA cloning and expression of UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase T1 from Toxoplasma gondii. Mol Biochem Parasitol 2003 0.95
75 In silico identification of specialized secretory-organelle proteins in apicomplexan parasites and in vivo validation in Toxoplasma gondii. PLoS One 2008 0.95
76 Amino-terminal control of transgenic protein expression levels in Toxoplasma gondii. Mol Biochem Parasitol 2002 0.95
77 Multiple functionally redundant signals mediate targeting to the apicoplast in the apicomplexan parasite Toxoplasma gondii. Eukaryot Cell 2004 0.95
78 Cysteine and serine protease inhibitors block intracellular development and disrupt the secretory pathway of Toxoplasma gondii. Microbes Infect 2002 0.94
79 Plastid-associated porphobilinogen synthase from Toxoplasma gondii: kinetic and structural properties validate therapeutic potential. J Biol Chem 2010 0.94
80 The search for the missing link: a relic plastid in Perkinsus? Int J Parasitol 2011 0.92
81 Isolation and characterization of TgVP1, a type I vacuolar H+-translocating pyrophosphatase from Toxoplasma gondii. The dynamics of its subcellular localization and the cellular effects of a diphosphonate inhibitor. J Biol Chem 2002 0.91
82 Targeted disruption of Toxoplasma gondii serine protease inhibitor 1 increases bradyzoite cyst formation in vitro and parasite tissue burden in mice. Infect Immun 2011 0.91
83 SchistoDB: an updated genome resource for the three key schistosomes of humans. Nucleic Acids Res 2012 0.91
84 Functional characterization of a novel Toxoplasma gondii glycosyltransferase: UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-T3. Arch Biochem Biophys 2004 0.91
85 Transcript initiation, polyadenylation, and functional promoter mapping for the dihydrofolate reductase-thymidylate synthase gene of Toxoplasma gondii. Mol Biochem Parasitol 2004 0.90
86 Toxoplasma gondii purine nucleoside phosphorylase biochemical characterization, inhibitor profiles, and comparison with the Plasmodium falciparum ortholog. J Biol Chem 2006 0.90
87 Replication and distribution of Toxoplasma gondii in the small intestine after oral infection with tissue cysts. Infect Immun 2013 0.89
88 Reranking candidate gene models with cross-species comparison for improved gene prediction. BMC Bioinformatics 2008 0.88
89 Malaria vaccines: if at first you don't succeed... Trends Parasitol 2004 0.87
90 The Eukaryotic Pathogen Databases: a functional genomic resource integrating data from human and veterinary parasites. Methods Mol Biol 2015 0.86
91 Crystal structure of Toxoplasma gondii porphobilinogen synthase: insights on octameric structure and porphobilinogen formation. J Biol Chem 2011 0.86
92 A novel GDP-dependent pyruvate kinase isozyme from Toxoplasma gondii localizes to both the apicoplast and the mitochondrion. J Biol Chem 2008 0.86
93 Subcellular antigen location influences T-cell activation during acute infection with Toxoplasma gondii. PLoS One 2011 0.84
94 PlasmoDB: exploring genomics and post-genomics data of the malaria parasite, Plasmodium falciparum. Redox Rep 2003 0.83
95 Pyruvate kinase type-II isozyme in Plasmodium falciparum localizes to the apicoplast. Parasitol Int 2008 0.82
96 An insertional trap for conditional gene expression in Toxoplasma gondii: identification of TAF250 as an essential gene. Mol Biochem Parasitol 2010 0.82
97 A systems biological view of intracellular pathogens. Immunol Rev 2011 0.81
98 The genomics of malaria infection. Trends Parasitol 2004 0.80
99 Cryptic organelle homology in apicomplexan parasites: insights from evolutionary cell biology. Curr Opin Microbiol 2013 0.79
100 Identity crisis? The need for systematic gene IDs. Trends Parasitol 2011 0.79
101 Toxoplasma gondii seroprevalence in Mali. J Parasitol 2012 0.77
102 Curation of the Plasmodium falciparum genome. Trends Parasitol 2004 0.76