Stephen F Konieczny

Author PubWeight™ 43.92‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice. Proc Natl Acad Sci U S A 2008 3.43
2 Acinar cells contribute to the molecular heterogeneity of pancreatic intraepithelial neoplasia. Am J Pathol 2007 2.87
3 The maturation of mucus-secreting gastric epithelial progenitors into digestive-enzyme secreting zymogenic cells requires Mist1. Development 2007 2.14
4 Mature chief cells are cryptic progenitors for metaplasia in the stomach. Gastroenterology 2010 2.02
5 Loss of the acinar-restricted transcription factor Mist1 accelerates Kras-induced pancreatic intraepithelial neoplasia. Gastroenterology 2009 1.89
6 A molecular signature of gastric metaplasia arising in response to acute parietal cell loss. Gastroenterology 2007 1.88
7 Extensive pancreas regeneration following acinar-specific disruption of Xbp1 in mice. Gastroenterology 2011 1.72
8 Mist1-KrasG12D knock-in mice develop mixed differentiation metastatic exocrine pancreatic carcinoma and hepatocellular carcinoma. Cancer Res 2006 1.69
9 The basic helix-loop-helix transcription factor E47 reprograms human pancreatic cancer cells to a quiescent acinar state with reduced tumorigenic potential. Pancreas 2015 1.42
10 XBP1 controls maturation of gastric zymogenic cells by induction of MIST1 and expansion of the rough endoplasmic reticulum. Gastroenterology 2010 1.37
11 Inhibition of Mist1 homodimer formation induces pancreatic acinar-to-ductal metaplasia. Mol Cell Biol 2004 1.33
12 Aberrant localization of intracellular organelles, Ca2+ signaling, and exocytosis in Mist1 null mice. J Biol Chem 2005 1.30
13 Identification and characterization of rain, a novel Ras-interacting protein with a unique subcellular localization. J Biol Chem 2004 1.20
14 Exocrine specific expression of Connexin32 is dependent on the basic helix-loop-helix transcription factor Mist1. J Cell Sci 2003 1.18
15 Identification of putative mammalian D-lactate dehydrogenase enzymes. Biochem Biophys Res Commun 2002 1.15
16 Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia. Gut 2012 1.14
17 Polo-like kinase 1 facilitates loss of Pten tumor suppressor-induced prostate cancer formation. J Biol Chem 2011 1.12
18 Missing pieces in understanding the intracellular trafficking of polycation/DNA complexes. J Control Release 2009 1.12
19 Induced Mist1 expression promotes remodeling of mouse pancreatic acinar cells. Gastroenterology 2012 1.07
20 Mist1 regulates pancreatic acinar cell proliferation through p21 CIP1/WAF1. Gastroenterology 2008 1.04
21 Plk1 phosphorylation of orc2 and hbo1 contributes to gemcitabine resistance in pancreatic cancer. Mol Cancer Ther 2012 1.02
22 Effects of the incorporation of a hydrophobic middle block into a PEG-polycation diblock copolymer on the physicochemical and cell interaction properties of the polymer-DNA complexes. Biomacromolecules 2008 1.02
23 Influence of nano-carrier architecture on in vitro siRNA delivery performance and in vivo biodistribution: polyplexes vs micelleplexes. ACS Nano 2011 0.98
24 MIST1 regulates the pancreatic acinar cell expression of Atp2c2, the gene encoding secretory pathway calcium ATPase 2. Exp Cell Res 2010 0.96
25 Identification of a basic helix-loop-helix transcription factor expressed in mammary gland alveolar cells and required for maintenance of the differentiated state. Mol Endocrinol 2006 0.96
26 Identification of novel MyoD gene targets in proliferating myogenic stem cells. Mol Cell Biol 2002 0.93
27 Epsins' novel role in cancer cell invasion. Commun Integr Biol 2011 0.87
28 Murine embryonic stem cell-derived pancreatic acinar cells recapitulate features of early pancreatic differentiation. Gastroenterology 2008 0.86
29 Nonproteolytic properties of murine alternatively spliced tissue factor: implications for integrin-mediated signaling in murine models. Mol Med 2012 0.85
30 The bHLH domain of Mistl is sufficient to activate gene transcription. Gene Expr 2007 0.84
31 RAS and the RAIN/RasIP1 effector. Methods Enzymol 2006 0.84
32 A fast fiber enhancer exists in the muscle regulatory factor 4 gene promoter. Biochem Biophys Res Commun 2002 0.81
33 Metaplastic metamorphoses in the mammalian pancreas. Gastroenterology 2007 0.81
34 A photo-degradable gene delivery system for enhanced nuclear gene transcription. Biomaterials 2013 0.78