Published in J Immunol on December 15, 2007
Regulation of immune responses by prostaglandin E2. J Immunol (2012) 3.93
Cyclic AMP: master regulator of innate immune cell function. Am J Respir Cell Mol Biol (2008) 2.00
Resolvins, specialized proresolving lipid mediators, and their potential roles in metabolic diseases. Cell Metab (2013) 1.45
An inflammatory mediator, prostaglandin E2, in colorectal cancer. Cancer J (2013) 1.01
Protease-activated receptors and prostaglandins in inflammatory lung disease. Br J Pharmacol (2009) 1.00
Prostaglandin E2 and the suppression of phagocyte innate immune responses in different organs. Mediators Inflamm (2012) 0.97
Phosphoinositide 3-kinases gamma and delta, linkers of coordinate C5a receptor-Fcgamma receptor activation and immune complex-induced inflammation. J Biol Chem (2008) 0.96
Leukotrienes target F-actin/cofilin-1 to enhance alveolar macrophage anti-fungal activity. J Biol Chem (2011) 0.92
PTEN directly activates the actin depolymerization factor cofilin-1 during PGE2-mediated inhibition of phagocytosis of fungi. Sci Signal (2012) 0.92
Beta1-adrenergic receptors promote focal adhesion signaling downregulation and myocyte apoptosis in acute volume overload. J Mol Cell Cardiol (2012) 0.90
Regulation of alveolar macrophage p40phox: hierarchy of activating kinases and their inhibition by PGE2. J Leukoc Biol (2012) 0.88
Rap1 activation is required for Fc gamma receptor-dependent phagocytosis. J Immunol (2008) 0.87
Impaired pulmonary immunity post-bone marrow transplant. Immunol Res (2011) 0.84
PTEN limits alveolar macrophage function against Pseudomonas aeruginosa after bone marrow transplantation. Am J Respir Cell Mol Biol (2011) 0.84
Defective pulmonary innate immune responses post-stem cell transplantation; review and results from one model system. Front Immunol (2013) 0.83
High constitutive Akt2 activity in U937 promonocytes: effective reduction of Akt2 phosphorylation by the histamine H2-receptor and the β2-adrenergic receptor. Naunyn Schmiedebergs Arch Pharmacol (2015) 0.77
Impaired neonatal macrophage phagocytosis is not explained by overproduction of prostaglandin E2. Respir Res (2011) 0.77
Implications of chemokine receptors and inflammatory lipids in cancer. Immunotargets Ther (2013) 0.75
Prostaglandin E2 As a Modulator of Viral Infections. Front Physiol (2017) 0.75
Mechanisms of pulmonary fibrosis. Annu Rev Med (2004) 4.37
Clostridium difficile ribotype does not predict severe infection. Clin Infect Dis (2012) 4.34
Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase. J Biol Chem (2003) 3.51
Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10). Am J Respir Crit Care Med (2005) 2.86
Acellular normal and fibrotic human lung matrices as a culture system for in vitro investigation. Am J Respir Crit Care Med (2012) 2.65
Prostaglandin E2 inhibits alveolar macrophage phagocytosis through an E-prostanoid 2 receptor-mediated increase in intracellular cyclic AMP. J Immunol (2004) 2.51
Leptin-deficient mice exhibit impaired host defense in Gram-negative pneumonia. J Immunol (2002) 2.27
Combinatorial activation of FAK and AKT by transforming growth factor-beta1 confers an anoikis-resistant phenotype to myofibroblasts. Cell Signal (2006) 2.22
Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis. Am J Respir Crit Care Med (2009) 2.15
Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E. prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation. Am J Respir Cell Mol Biol (2003) 2.14
Cutting edge: macrophage inhibition by cyclic AMP (cAMP): differential roles of protein kinase A and exchange protein directly activated by cAMP-1. J Immunol (2005) 2.01
Cyclic AMP: master regulator of innate immune cell function. Am J Respir Cell Mol Biol (2008) 2.00
Differential stem- and progenitor-cell trafficking by prostaglandin E2. Nature (2013) 1.99
Leptin corrects host defense defects after acute starvation in murine pneumococcal pneumonia. Am J Respir Crit Care Med (2005) 1.97
An essential role for fibronectin extra type III domain A in pulmonary fibrosis. Am J Respir Crit Care Med (2007) 1.91
Evidence for tissue-resident mesenchymal stem cells in human adult lung from studies of transplanted allografts. J Clin Invest (2007) 1.87
Fever and hypothermia in systemic inflammation: recent discoveries and revisions. Front Biosci (2005) 1.75
Misoprostol impairs female reproductive tract innate immunity against Clostridium sordellii. J Immunol (2008) 1.74
Efferocytosis impairs pulmonary macrophage and lung antibacterial function via PGE2/EP2 signaling. J Exp Med (2009) 1.74
The myofibroblast matrix: implications for tissue repair and fibrosis. J Pathol (2013) 1.73
FibronectinEDA promotes chronic cutaneous fibrosis through Toll-like receptor signaling. Sci Transl Med (2014) 1.72
Prostaglandin E(2) inhibits collagen expression and proliferation in patient-derived normal lung fibroblasts via E prostanoid 2 receptor and cAMP signaling. Am J Physiol Lung Cell Mol Physiol (2006) 1.66
Leukotrienes enhance the bactericidal activity of alveolar macrophages against Klebsiella pneumoniae through the activation of NADPH oxidase. Blood (2005) 1.62
Recipient-derived EDA fibronectin promotes cardiac allograft fibrosis. J Pathol (2012) 1.57
Critical role of prostaglandin E2 overproduction in impaired pulmonary host response following bone marrow transplantation. J Immunol (2006) 1.56
Fibrotic extracellular matrix activates a profibrotic positive feedback loop. J Clin Invest (2014) 1.54
Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report. Am J Respir Crit Care Med (2014) 1.54
Depression, antidepressant medications, and risk of Clostridium difficile infection. BMC Med (2013) 1.54
Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H(2) synthases. Proc Natl Acad Sci U S A (2002) 1.54
Prostaglandin E2 suppresses bacterial killing in alveolar macrophages by inhibiting NADPH oxidase. Am J Respir Cell Mol Biol (2007) 1.52
Roles of cysteinyl leukotrienes in airway inflammation, smooth muscle function, and remodeling. J Allergy Clin Immunol (2003) 1.52
Prostaglandin E2 as an inhibitory modulator of fibrogenesis in human lung allografts. Am J Respir Crit Care Med (2012) 1.47
Prostaglandin E2 synthesis and suppression of fibroblast proliferation by alveolar epithelial cells is cyclooxygenase-2-dependent. Am J Respir Cell Mol Biol (2002) 1.47
Prostaglandin E(2) inhibits fibroblast migration by E-prostanoid 2 receptor-mediated increase in PTEN activity. Am J Respir Cell Mol Biol (2004) 1.47
Prostaglandin E2 inhibits specific lung fibroblast functions via selective actions of PKA and Epac-1. Am J Respir Cell Mol Biol (2008) 1.45
Periostin promotes fibrosis and predicts progression in patients with idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol (2012) 1.44
Lung resident mesenchymal stem cells isolated from human lung allografts inhibit T cell proliferation via a soluble mediator. J Immunol (2008) 1.42
Prostaglandin E(2) induces fibroblast apoptosis by modulating multiple survival pathways. FASEB J (2009) 1.41
Microbiome data distinguish patients with Clostridium difficile infection and non-C. difficile-associated diarrhea from healthy controls. MBio (2014) 1.40
Plasminogen activator inhibitor-1 impairs alveolar epithelial repair by binding to vitronectin. Am J Respir Cell Mol Biol (2004) 1.34
Alveolar epithelial cell inhibition of fibroblast proliferation is regulated by MCP-1/CCR2 and mediated by PGE2. Am J Physiol Lung Cell Mol Physiol (2002) 1.33
Bleomycin-induced E prostanoid receptor changes alter fibroblast responses to prostaglandin E2. J Immunol (2005) 1.33
Human iPS cell-derived alveolar epithelium repopulates lung extracellular matrix. J Clin Invest (2013) 1.31
Cefoperazone-treated mice as an experimental platform to assess differential virulence of Clostridium difficile strains. Gut Microbes (2011) 1.29
Variable prostaglandin E2 resistance in fibroblasts from patients with usual interstitial pneumonia. Am J Respir Crit Care Med (2007) 1.29
Role of granulocyte macrophage colony-stimulating factor during gram-negative lung infection with Pseudomonas aeruginosa. Am J Respir Cell Mol Biol (2006) 1.28
The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in humans and mice. J Clin Invest (2010) 1.27
Leukotriene B4 amplifies NF-κB activation in mouse macrophages by reducing SOCS1 inhibition of MyD88 expression. J Clin Invest (2011) 1.24
Hypermethylation of PTGER2 confers prostaglandin E2 resistance in fibrotic fibroblasts from humans and mice. Am J Pathol (2010) 1.23
Synthetic prostacyclin analogs differentially regulate macrophage function via distinct analog-receptor binding specificities. J Immunol (2007) 1.23
Procalcitonin levels associate with severity of Clostridium difficile infection. PLoS One (2013) 1.22
Cigarette smoke exposure impairs pulmonary bacterial clearance and alveolar macrophage complement-mediated phagocytosis of Streptococcus pneumoniae. Infect Immun (2009) 1.22
Impaired synthesis of prostaglandin E2 by lung fibroblasts and alveolar epithelial cells from GM-CSF-/- mice: implications for fibroproliferation. Am J Physiol Lung Cell Mol Physiol (2003) 1.20
Growth kinetics of extremely halophilic archaea (family halobacteriaceae) as revealed by arrhenius plots. J Bacteriol (2005) 1.19
PGE(2) inhibition of TGF-beta1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesion-dependent signaling. Am J Physiol Lung Cell Mol Physiol (2007) 1.19
Pulmonary sarcoidosis. Semin Respir Crit Care Med (2007) 1.19
Necrotizing fasciitis: pathogenesis and treatment. Expert Rev Anti Infect Ther (2005) 1.18
Leukotrienes are essential for the control of Leishmania amazonensis infection and contribute to strain variation in susceptibility. J Immunol (2006) 1.18
Short communication: differences between macrophages and dendritic cells in the cyclic AMP-dependent regulation of lipopolysaccharide-induced cytokine and chemokine synthesis. J Interferon Cytokine Res (2006) 1.16
Nuclear localization of 5-lipoxygenase as a determinant of leukotriene B4 synthetic capacity. Proc Natl Acad Sci U S A (2003) 1.15
The relationship between phenotype, ribotype, and clinical disease in human Clostridium difficile isolates. Anaerobe (2013) 1.14
Cysteinyl leukotrienes are autocrine and paracrine regulators of fibrocyte function. J Immunol (2007) 1.14
Leukotriene B4 is a physiologically relevant endogenous peroxisome proliferator-activated receptor-alpha agonist. J Biol Chem (2010) 1.14
Understanding increased mortality in Clostridium difficile-infected older adults. Clin Infect Dis (2013) 1.13
Inhibition of leukotriene biosynthesis abrogates the host control of Mycobacterium tuberculosis. Microbes Infect (2007) 1.13
EDA-containing cellular fibronectin induces fibroblast differentiation through binding to alpha4beta7 integrin receptor and MAPK/Erk 1/2-dependent signaling. FASEB J (2010) 1.11
Prostaglandin E2 mediates IL-1beta-related fibroblast mitogenic effects in acute lung injury through differential utilization of prostanoid receptors. J Immunol (2008) 1.11
Epidemiology of Clostridium difficile infection. J Pharm Pract (2013) 1.10
E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection. J Immunol (2009) 1.10
The class A scavenger receptor, macrophage receptor with collagenous structure, is the major phagocytic receptor for Clostridium sordellii expressed by human decidual macrophages. J Immunol (2010) 1.08
Resident tissue-specific mesenchymal progenitor cells contribute to fibrogenesis in human lung allografts. Am J Pathol (2011) 1.07
Prostaglandin E₂ increases fibroblast gene-specific and global DNA methylation via increased DNA methyltransferase expression. FASEB J (2012) 1.07
Leptin modulates neutrophil phagocytosis of Klebsiella pneumoniae. Infect Immun (2003) 1.06
Leptin augments alveolar macrophage leukotriene synthesis by increasing phospholipase activity and enhancing group IVC iPLA2 (cPLA2gamma) protein expression. Am J Physiol Lung Cell Mol Physiol (2004) 1.05
Blocking macrophage leukotriene b4 prevents endothelial injury and reverses pulmonary hypertension. Sci Transl Med (2013) 1.05
Poor functional status as a risk factor for severe Clostridium difficile infection in hospitalized older adults. J Am Geriatr Soc (2013) 1.05
Coevolution of TH1, TH2, and TH17 responses during repeated pulmonary exposure to Aspergillus fumigatus conidia. Infect Immun (2010) 1.05
Extensive phenotyping of individuals at risk for familial interstitial pneumonia reveals clues to the pathogenesis of interstitial lung disease. Am J Respir Crit Care Med (2015) 1.04
Clostridium difficile ribotype diversity at six health care institutions in the United States. J Clin Microbiol (2013) 1.04
Eicosanoid lipid mediators in fibrotic lung diseases: ready for prime time? Chest (2008) 1.04