Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet.
|
N Engl J Med
|
2008
|
12.41
|
2
|
Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects.
|
N Engl J Med
|
2006
|
9.53
|
3
|
T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance.
|
Arterioscler Thromb Vasc Biol
|
2008
|
5.44
|
4
|
Antioxidants prevent health-promoting effects of physical exercise in humans.
|
Proc Natl Acad Sci U S A
|
2009
|
5.19
|
5
|
Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5.
|
Nature
|
2010
|
5.01
|
6
|
Evidence for a role of developmental genes in the origin of obesity and body fat distribution.
|
Proc Natl Acad Sci U S A
|
2006
|
4.81
|
7
|
Effects of Initiating Moderate Alcohol Intake on Cardiometabolic Risk in Adults With Type 2 Diabetes: A 2-Year Randomized, Controlled Trial.
|
Ann Intern Med
|
2015
|
3.78
|
8
|
Insulin-sensitive obesity.
|
Am J Physiol Endocrinol Metab
|
2010
|
3.46
|
9
|
A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism.
|
Nature
|
2012
|
3.35
|
10
|
Macrophage infiltration into omental versus subcutaneous fat across different populations: effect of regional adiposity and the comorbidities of obesity.
|
J Clin Endocrinol Metab
|
2007
|
2.81
|
11
|
Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat mass.
|
Cell Metab
|
2007
|
2.69
|
12
|
Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis.
|
Nat Genet
|
2007
|
2.48
|
13
|
Plasma visfatin concentrations and fat depot-specific mRNA expression in humans.
|
Diabetes
|
2005
|
2.34
|
14
|
Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance.
|
Diabetologia
|
2015
|
2.25
|
15
|
Variants in CPA1 are strongly associated with early onset chronic pancreatitis.
|
Nat Genet
|
2013
|
2.10
|
16
|
Serum levels of the adipokine progranulin depend on renal function.
|
Diabetes Care
|
2012
|
2.03
|
17
|
Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth.
|
Diabetes
|
2008
|
1.97
|
18
|
Serum vaspin concentrations in human obesity and type 2 diabetes.
|
Diabetes
|
2007
|
1.96
|
19
|
Gender differences of adiponectin levels develop during the progression of puberty and are related to serum androgen levels.
|
J Clin Endocrinol Metab
|
2004
|
1.92
|
20
|
Serum levels of adipokine retinol-binding protein-4 in relation to renal function.
|
Diabetes Care
|
2007
|
1.85
|
21
|
MicroRNA expression in human omental and subcutaneous adipose tissue.
|
PLoS One
|
2009
|
1.81
|
22
|
Glypican-4 enhances insulin signaling via interaction with the insulin receptor and serves as a novel adipokine.
|
Diabetes
|
2012
|
1.76
|
23
|
Effect of a 4 week physical training program on plasma concentrations of inflammatory markers in patients with abnormal glucose tolerance.
|
Eur J Endocrinol
|
2006
|
1.76
|
24
|
Altered fiber distribution and fiber-specific glycolytic and oxidative enzyme activity in skeletal muscle of patients with type 2 diabetes.
|
Diabetes Care
|
2006
|
1.63
|
25
|
Serum levels of fibroblast growth factor-21 are increased in chronic and acute renal dysfunction.
|
Clin Endocrinol (Oxf)
|
2014
|
1.49
|
26
|
Altered autophagy in human adipose tissues in obesity.
|
J Clin Endocrinol Metab
|
2010
|
1.47
|
27
|
Serum levels of the adipokine FGF21 depend on renal function.
|
Diabetes Care
|
2008
|
1.42
|
28
|
Serum progranulin concentrations may be associated with macrophage infiltration into omental adipose tissue.
|
Diabetes
|
2008
|
1.42
|
29
|
Vaspin gene expression in human adipose tissue: association with obesity and type 2 diabetes.
|
Biochem Biophys Res Commun
|
2005
|
1.30
|
30
|
Dietary intervention to reverse carotid atherosclerosis.
|
Circulation
|
2010
|
1.28
|
31
|
Adipokine pattern in subjects with impaired fasting glucose and impaired glucose tolerance in comparison to normal glucose tolerance and diabetes.
|
PLoS One
|
2010
|
1.25
|
32
|
Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance.
|
PLoS Genet
|
2010
|
1.22
|
33
|
Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass changes.
|
J Proteome Res
|
2011
|
1.20
|
34
|
Serum levels of the adipokine vaspin in relation to metabolic and renal parameters.
|
J Clin Endocrinol Metab
|
2007
|
1.19
|
35
|
Serum levels of the atherosclerosis biomarker sTWEAK are decreased in type 2 diabetes and end-stage renal disease.
|
Atherosclerosis
|
2007
|
1.18
|
36
|
Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs.
|
Hum Mol Genet
|
2009
|
1.16
|
37
|
Positional cloning of zinc finger domain transcription factor Zfp69, a candidate gene for obesity-associated diabetes contributed by mouse locus Nidd/SJL.
|
PLoS Genet
|
2009
|
1.15
|
38
|
Gene expression of PPARgamma and PGC-1alpha in human omental and subcutaneous adipose tissues is related to insulin resistance markers and mediates beneficial effects of physical training.
|
Eur J Endocrinol
|
2009
|
1.14
|
39
|
Adipocyte dysfunction, inflammation and metabolic syndrome.
|
Rev Endocr Metab Disord
|
2014
|
1.12
|
40
|
Effects of genetic variation in the human retinol binding protein-4 gene (RBP4) on insulin resistance and fat depot-specific mRNA expression.
|
Diabetes
|
2007
|
1.12
|
41
|
Long-term exercise training decreases interleukin-6 (IL-6) serum levels in subjects with impaired glucose tolerance: effect of the -174G/C variant in IL-6 gene.
|
Eur J Endocrinol
|
2008
|
1.11
|
42
|
Effects of weight loss and exercise on chemerin serum concentrations and adipose tissue expression in human obesity.
|
Metabolism
|
2011
|
1.11
|
43
|
Adipose tissue expression and genetic variants of the bone morphogenetic protein receptor 1A gene (BMPR1A) are associated with human obesity.
|
Diabetes
|
2009
|
1.11
|
44
|
Molecular characteristics of serum visfatin and differential detection by immunoassays.
|
J Clin Endocrinol Metab
|
2007
|
1.11
|
45
|
Implication of progranulin and C1q/TNF-related protein-3 (CTRP3) on inflammation and atherosclerosis in subjects with or without metabolic syndrome.
|
PLoS One
|
2013
|
1.10
|
46
|
Insulin up-regulates natriuretic peptide clearance receptor expression in the subcutaneous fat depot in obese subjects: a missing link between CVD risk and obesity?
|
J Clin Endocrinol Metab
|
2012
|
1.10
|
47
|
Vaspin serum concentrations in patients with carotid stenosis.
|
Atherosclerosis
|
2008
|
1.08
|
48
|
Genomic insights into the origin of farming in the ancient Near East.
|
Nature
|
2016
|
1.07
|
49
|
Serum levels of adipocyte fatty acid-binding protein (AFABP) are increased in chronic haemodialysis (CD).
|
Clin Endocrinol (Oxf)
|
2008
|
1.07
|
50
|
Palmitate induced IL-6 and MCP-1 expression in human bladder smooth muscle cells provides a link between diabetes and urinary tract infections.
|
PLoS One
|
2010
|
1.06
|
51
|
Adiponectin expression in humans is dependent on differentiation of adipocytes and down-regulated by humoral serum components of high molecular weight.
|
Biochem Biophys Res Commun
|
2005
|
1.06
|
52
|
Extended longevity and insulin signaling in adipose tissue.
|
Exp Gerontol
|
2005
|
1.06
|
53
|
Mitogen-activated protein kinases, inhibitory-kappaB kinase, and insulin signaling in human omental versus subcutaneous adipose tissue in obesity.
|
Endocrinology
|
2007
|
1.06
|
54
|
Local proliferation of macrophages in adipose tissue during obesity-induced inflammation.
|
Diabetologia
|
2013
|
1.05
|
55
|
The ARF-like GTPase ARFRP1 is essential for lipid droplet growth and is involved in the regulation of lipolysis.
|
Mol Cell Biol
|
2009
|
1.03
|
56
|
Adipose dipeptidyl peptidase-4 and obesity: correlation with insulin resistance and depot-specific release from adipose tissue in vivo and in vitro.
|
Diabetes Care
|
2013
|
1.03
|
57
|
Extracellular fatty acid synthase: a possible surrogate biomarker of insulin resistance.
|
Diabetes
|
2010
|
1.02
|
58
|
Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance.
|
Nat Med
|
2013
|
1.02
|
59
|
Pro-inflammatory macrophages increase in skeletal muscle of high fat-fed mice and correlate with metabolic risk markers in humans.
|
Obesity (Silver Spring)
|
2013
|
1.01
|
60
|
Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesity.
|
PLoS One
|
2012
|
1.01
|
61
|
Genetic variation in the visfatin gene (PBEF1) and its relation to glucose metabolism and fat-depot-specific messenger ribonucleic acid expression in humans.
|
J Clin Endocrinol Metab
|
2006
|
1.01
|
62
|
Visfatin/PBEF/Nampt: structure, regulation and potential function of a novel adipokine.
|
Clin Sci (Lond)
|
2008
|
1.00
|
63
|
Serum levels of the adipokine zinc-α2-glycoprotein are increased in chronic hemodialysis.
|
Metabolism
|
2010
|
0.99
|
64
|
The genetics of fat distribution.
|
Diabetologia
|
2014
|
0.99
|
65
|
Serum levels of the myokine irisin in relation to metabolic and renal function.
|
Eur J Endocrinol
|
2014
|
0.99
|
66
|
Clinical inertia in individualising care for diabetes: is there time to do more in type 2 diabetes?
|
Diabetes Ther
|
2014
|
0.98
|
67
|
Renal function following three distinct weight loss dietary strategies during 2 years of a randomized controlled trial.
|
Diabetes Care
|
2013
|
0.97
|
68
|
Adipocyte size threshold matters: link with risk of type 2 diabetes and improved insulin resistance after gastric bypass.
|
J Clin Endocrinol Metab
|
2014
|
0.96
|
69
|
Serum fibroblast growth factor 21 levels in gestational diabetes mellitus in relation to insulin resistance and dyslipidemia.
|
Metabolism
|
2009
|
0.96
|
70
|
Adipose tissue foam cells are present in human obesity.
|
J Clin Endocrinol Metab
|
2013
|
0.96
|
71
|
Dairy calcium intake, serum vitamin D, and successful weight loss.
|
Am J Clin Nutr
|
2010
|
0.95
|
72
|
Defining the human adipose tissue proteome to reveal metabolic alterations in obesity.
|
J Proteome Res
|
2014
|
0.94
|
73
|
Serum levels of the adipokine chemerin in relation to renal function.
|
Diabetes Care
|
2009
|
0.93
|
74
|
An inflammatory micro-environment promotes human adipocyte apoptosis.
|
Mol Cell Endocrinol
|
2011
|
0.93
|
75
|
Low vs. higher-dose dark chocolate and blood pressure in cardiovascular high-risk patients.
|
Am J Hypertens
|
2010
|
0.93
|
76
|
Evaluation of a computer based interactive diabetes education program designed to train the estimation of the energy or carbohydrate contents of foods.
|
Patient Educ Couns
|
2002
|
0.92
|
77
|
The adipokine SAA3 is induced by interleukin-1beta in mouse adipocytes.
|
J Cell Biochem
|
2008
|
0.91
|
78
|
Lack of association between the tagging SNP A+930-->G of SOCS3 and type 2 diabetes mellitus: meta-analysis of four independent study populations.
|
PLoS One
|
2008
|
0.91
|
79
|
Serum levels of the adipokine chemerin are increased in preeclampsia during and 6 months after pregnancy.
|
Regul Pept
|
2011
|
0.91
|
80
|
Genetic and evolutionary analyses of the human bone morphogenetic protein receptor 2 (BMPR2) in the pathophysiology of obesity.
|
PLoS One
|
2011
|
0.90
|
81
|
Loss of function of Ifi202b by a microdeletion on chromosome 1 of C57BL/6J mice suppresses 11β-hydroxysteroid dehydrogenase type 1 expression and development of obesity.
|
Hum Mol Genet
|
2012
|
0.89
|
82
|
Quantitative measurement of full-length and C-terminal proteolyzed RBP4 in serum of normal and insulin-resistant humans using a novel mass spectrometry immunoassay.
|
Endocrinology
|
2012
|
0.89
|
83
|
Growth hormone is a positive regulator of adiponectin receptor 2 in 3T3-L1 adipocytes.
|
FEBS Lett
|
2004
|
0.88
|
84
|
Circulating levels of the adipokine chemerin in gestational diabetes mellitus.
|
Horm Res Paediatr
|
2010
|
0.88
|
85
|
Amyloid precursor protein expression is induced by tumor necrosis factor alpha in 3T3-L1 adipocytes.
|
J Cell Biochem
|
2009
|
0.88
|
86
|
Circulating chemerin decreases in response to a combined strength and endurance training.
|
Endocrine
|
2013
|
0.88
|
87
|
Dimerization of adiponectin receptor 1 is inhibited by adiponectin.
|
J Cell Sci
|
2010
|
0.88
|
88
|
TCF7L2 gene expression in human visceral and subcutaneous adipose tissue is differentially regulated but not associated with type 2 diabetes mellitus.
|
Metabolism
|
2008
|
0.88
|
89
|
The polygenetically inherited metabolic syndrome of WOKW rats is associated with insulin resistance and altered gene expression in adipose tissue.
|
Diabetes Metab Res Rev
|
2006
|
0.87
|
90
|
Effects of extended-release niacin on lipid profile and adipocyte biology in patients with impaired glucose tolerance.
|
Atherosclerosis
|
2008
|
0.87
|
91
|
Long- but not short-term multifactorial intervention with focus on exercise training improves coronary endothelial dysfunction in diabetes mellitus type 2 and coronary artery disease.
|
Eur Heart J
|
2009
|
0.86
|
92
|
Role of genetic variation in the cannabinoid type 1 receptor gene (CNR1) in the pathophysiology of human obesity.
|
Pharmacogenomics
|
2010
|
0.86
|
93
|
Serum levels of adipocyte fatty acid binding protein are increased in gestational diabetes mellitus.
|
Eur J Endocrinol
|
2008
|
0.86
|
94
|
Adipokines influencing metabolic and cardiovascular disease are differentially regulated in maintenance hemodialysis.
|
Metabolism
|
2008
|
0.86
|
95
|
Endocrine disrupting chemicals affect the adipogenic differentiation of mesenchymal stem cells in distinct ontogenetic windows.
|
Biochem Biophys Res Commun
|
2011
|
0.85
|
96
|
Retinol-binding protein 4 and new adipocytokines in nonalcoholic fatty liver disease.
|
Curr Pharm Des
|
2010
|
0.85
|
97
|
Carbonylated plasma proteins as potential biomarkers of obesity induced type 2 diabetes mellitus.
|
J Proteome Res
|
2014
|
0.85
|
98
|
Predictive accuracy of single- and multi-slice MRI for the estimation of total visceral adipose tissue in overweight to severely obese patients.
|
NMR Biomed
|
2015
|
0.85
|
99
|
Software for automated MRI-based quantification of abdominal fat and preliminary evaluation in morbidly obese patients.
|
J Magn Reson Imaging
|
2012
|
0.84
|
100
|
Regenerative capacity differs between micro- and macrovesicular hepatic steatosis.
|
Exp Toxicol Pathol
|
2007
|
0.84
|
101
|
Vaspin inhibits kallikrein 7 by serpin mechanism.
|
Cell Mol Life Sci
|
2013
|
0.84
|
102
|
Serum levels of angiopoietin-related growth factor in diabetes mellitus and chronic hemodialysis.
|
Metabolism
|
2009
|
0.83
|
103
|
COL6A3 expression in adipocytes associates with insulin resistance and depends on PPARγ and adipocyte size.
|
Obesity (Silver Spring)
|
2014
|
0.83
|
104
|
Association of glypican-4 with body fat distribution, insulin resistance, and nonalcoholic fatty liver disease.
|
J Clin Endocrinol Metab
|
2013
|
0.83
|
105
|
Shox2 is a molecular determinant of depot-specific adipocyte function.
|
Proc Natl Acad Sci U S A
|
2013
|
0.83
|
106
|
Effects of weight loss and exercise on apelin serum concentrations and adipose tissue expression in human obesity.
|
Obes Facts
|
2013
|
0.83
|
107
|
Preliminary report: circulating levels of the adipokine vaspin in gestational diabetes mellitus and preeclampsia.
|
Metabolism
|
2009
|
0.83
|
108
|
R1467H variant in the rho guanine nucleotide exchange factor 11 (ARHGEF11) is associated with impaired glucose tolerance and type 2 diabetes in German Caucasians.
|
J Hum Genet
|
2008
|
0.83
|
109
|
Circulating anandamide and blood pressure in patients with obstructive sleep apnea.
|
J Hypertens
|
2012
|
0.82
|
110
|
Fibroblast growth factor-21 serum concentrations are associated with metabolic and hepatic markers in humans.
|
J Endocrinol
|
2013
|
0.82
|
111
|
Association between plasma nonesterified fatty acids species and adipose tissue fatty acid composition.
|
PLoS One
|
2013
|
0.82
|
112
|
Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression.
|
Obesity (Silver Spring)
|
2013
|
0.82
|
113
|
Beneficial effects of a 4-week exercise program on plasma concentrations of adhesion molecules.
|
Diabetes Care
|
2007
|
0.82
|
114
|
Global DNA methylation levels in human adipose tissue are related to fat distribution and glucose homeostasis.
|
Diabetologia
|
2014
|
0.82
|
115
|
Serum levels of the adipokine fibroblast growth factor-21 are increased in preeclampsia.
|
Cytokine
|
2013
|
0.81
|
116
|
Repin1 maybe involved in the regulation of cell size and glucose transport in adipocytes.
|
Biochem Biophys Res Commun
|
2010
|
0.81
|
117
|
Short-term changes of the urine metabolome after bariatric surgery.
|
OMICS
|
2012
|
0.81
|
118
|
Serum vaspin concentrations are decreased after exercise-induced oxidative stress.
|
Obes Facts
|
2010
|
0.81
|
119
|
Autophagy in adipose tissue.
|
Obes Facts
|
2012
|
0.81
|
120
|
COMP-angiopoietin-1 recovers molecular biomarkers of neuropathy and improves vascularisation in sciatic nerve of ob/ob mice.
|
PLoS One
|
2012
|
0.81
|
121
|
Role of vaspin in human eating behaviour.
|
PLoS One
|
2013
|
0.81
|
122
|
Altered sciatic nerve fiber morphology and endoneural microvessels in mouse models relevant for obesity, peripheral diabetic polyneuropathy, and the metabolic syndrome.
|
J Neurosci Res
|
2011
|
0.81
|
123
|
C57BL/6JRj mice are protected against diet induced obesity (DIO).
|
Biochem Biophys Res Commun
|
2011
|
0.81
|
124
|
Defective peripheral nerve development is linked to abnormal architecture and metabolic activity of adipose tissue in Nscl-2 mutant mice.
|
PLoS One
|
2009
|
0.81
|
125
|
Benefits of foods supplemented with vegetable oils rich in α-linolenic, stearidonic or docosahexaenoic acid in hypertriglyceridemic subjects: a double-blind, randomized, controlled trail.
|
Eur J Nutr
|
2014
|
0.81
|
126
|
Does retinol-binding protein 4 cause or reflect fatty liver disease?
|
Hepatology
|
2008
|
0.80
|
127
|
Glycation sites of human plasma proteins are affected to different extents by hyperglycemic conditions in type 2 diabetes mellitus.
|
Anal Bioanal Chem
|
2014
|
0.80
|
128
|
Access to gram scale amounts of functional globular adiponectin from E. coli inclusion bodies by alkaline-shock solubilization.
|
Biochem Biophys Res Commun
|
2010
|
0.80
|
129
|
Circulating high-molecular-weight adiponectin is upregulated in preeclampsia and is related to insulin sensitivity and renal function.
|
Eur J Endocrinol
|
2008
|
0.80
|
130
|
Nicotinamide nucleotide transhydrogenase mRNA expression is related to human obesity.
|
Obesity (Silver Spring)
|
2013
|
0.80
|
131
|
Adipose tissue depot specific promoter methylation of TMEM18.
|
J Mol Med (Berl)
|
2014
|
0.80
|
132
|
An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects.
|
PLoS One
|
2013
|
0.80
|
133
|
A common variant of PNPLA3 (p.I148M) is not associated with alcoholic chronic pancreatitis.
|
PLoS One
|
2012
|
0.79
|
134
|
Fas (CD95) expression in myeloid cells promotes obesity‐induced muscle insulin resistance.
|
EMBO Mol Med
|
2014
|
0.79
|
135
|
Insulin administration acutely decreases vaspin serum concentrations in humans.
|
Obes Facts
|
2013
|
0.79
|
136
|
SORLA facilitates insulin receptor signaling in adipocytes and exacerbates obesity.
|
J Clin Invest
|
2016
|
0.79
|
137
|
TSH compensates thyroid-specific IGF-I receptor knockout and causes papillary thyroid hyperplasia.
|
Mol Endocrinol
|
2011
|
0.78
|
138
|
Complete analysis of the human mesotrypsinogen gene (PRSS3) in patients with chronic pancreatitis.
|
Pancreatology
|
2010
|
0.78
|
139
|
Exercise training restores the endothelial response to vascular growth factors in patients with stable coronary artery disease.
|
Eur J Prev Cardiol
|
2011
|
0.78
|
140
|
Serum levels of the adipokine adipocyte fatty acid-binding protein are increased in preeclampsia.
|
Am J Hypertens
|
2008
|
0.78
|
141
|
Vaspin--a link of obesity and psoriasis?
|
Exp Dermatol
|
2012
|
0.78
|
142
|
Adiponectin promotes the migration of circulating angiogenic cells through p38-mediated induction of the CXCR4 receptor.
|
Int J Cardiol
|
2012
|
0.78
|
143
|
Effect of genetic variation in the human fatty acid synthase gene (FASN) on obesity and fat depot-specific mRNA expression.
|
Obesity (Silver Spring)
|
2009
|
0.78
|
144
|
Genetic analyses of heme oxygenase 1 (HMOX1) in different forms of pancreatitis.
|
PLoS One
|
2012
|
0.78
|
145
|
Differential expression of novel adiponectin receptor-1 transcripts in skeletal muscle of subjects with normal glucose tolerance and type 2 diabetes.
|
Diabetes
|
2011
|
0.78
|
146
|
Efficacy and safety of the weight-loss drug rimonabant.
|
Lancet
|
2008
|
0.77
|
147
|
Mutational analysis of the gene encoding the zymogen granule membrane glycoprotein 2 (GP2) in patients with chronic pancreatitis.
|
Pancreas
|
2010
|
0.77
|
148
|
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