Published in Appl Physiol Nutr Metab on October 01, 2007
Hypoxia-inducible factors and the response to hypoxic stress. Mol Cell (2010) 7.20
Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance. Diabetes (2008) 2.14
Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model. J Hepatol (2010) 2.09
Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption. Diabetes (2010) 1.97
The role of mitochondria in the pathophysiology of skeletal muscle insulin resistance. Endocr Rev (2009) 1.57
Daily exercise vs. caloric restriction for prevention of nonalcoholic fatty liver disease in the OLETF rat model. Am J Physiol Gastrointest Liver Physiol (2011) 1.41
Intramuscular triacylglycerol and insulin resistance: guilty as charged or wrongly accused? Biochim Biophys Acta (2009) 1.34
Global gene expression profiles of subcutaneous adipose and muscle from glucose-tolerant, insulin-sensitive, and insulin-resistant individuals matched for BMI. Diabetes (2011) 1.31
Opposite regulation of CD36 ubiquitination by fatty acids and insulin: effects on fatty acid uptake. J Biol Chem (2008) 1.22
Exercise training-induced regulation of mitochondrial quality. Exerc Sport Sci Rev (2012) 1.11
A high-fat diet elicits differential responses in genes coordinating oxidative metabolism in skeletal muscle of lean and obese individuals. J Clin Endocrinol Metab (2010) 1.09
Muscle-specific inositide phosphatase (MIP/MTMR14) is reduced with age and its loss accelerates skeletal muscle aging process by altering calcium homeostasis. Aging (Albany NY) (2010) 1.08
Intermuscular and intramuscular adipose tissues: Bad vs. good adipose tissues. Adipocyte (2014) 1.08
Atypical antipsychotics rapidly and inappropriately switch peripheral fuel utilization to lipids, impairing metabolic flexibility in rodents. Schizophr Bull (2010) 1.06
Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity. Diabetes (2013) 1.06
Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis. Biochim Biophys Acta (2011) 1.05
Apelin treatment increases complete Fatty Acid oxidation, mitochondrial oxidative capacity, and biogenesis in muscle of insulin-resistant mice. Diabetes (2011) 1.05
IL-6 induces lipolysis and mitochondrial dysfunction, but does not affect insulin-mediated glucose transport in 3T3-L1 adipocytes. J Bioenerg Biomembr (2011) 1.04
New insights from rodent models of fatty liver disease. Antioxid Redox Signal (2011) 1.03
Expression of oxidative phosphorylation components in mitochondria of long-living Ames dwarf mice. Age (Dordr) (2011) 0.95
Effect of caloric restriction with and without exercise on metabolic intermediates in nonobese men and women. J Clin Endocrinol Metab (2010) 0.95
Protective effects of Acyl-coA thioesterase 1 on diabetic heart via PPARα/PGC1α signaling. PLoS One (2012) 0.95
Carcinoembryonic antigen-related cell adhesion molecule 2 controls energy balance and peripheral insulin action in mice. Gastroenterology (2010) 0.93
Skeletal muscle lipid flux: running water carries no poison. Am J Physiol Endocrinol Metab (2011) 0.91
Exercise reduces appetite and traffics excess nutrients away from energetically efficient pathways of lipid deposition during the early stages of weight regain. Am J Physiol Regul Integr Comp Physiol (2011) 0.90
Mechanisms governing the health and performance benefits of exercise. Br J Pharmacol (2013) 0.89
Mitochondrial fatty acid oxidation in obesity. Antioxid Redox Signal (2012) 0.88
Comparative studies of skeletal muscle proteome and transcriptome profilings between pig breeds. Mamm Genome (2010) 0.87
Drugs in sport: a scientist-athlete's perspective: from ambition to neurochemistry. Br J Pharmacol (2008) 0.86
Elevated FGF21 secretion, PGC-1α and ketogenic enzyme expression are hallmarks of iron-sulfur cluster depletion in human skeletal muscle. Hum Mol Genet (2013) 0.85
Alterations in peroxisome proliferator-activated receptor mRNA expression in skeletal muscle after acute and repeated bouts of exercise. Mol Cell Biochem (2009) 0.84
Hydroxypropyl methylcellulose, a viscous soluble fiber, reduces insulin resistance and decreases fatty liver in Zucker Diabetic Fatty rats. Nutr Metab (Lond) (2012) 0.84
Muscle-Specific Overexpression of PGC-1α Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction. Diabetes (2014) 0.81
Altered fetal skeletal muscle nutrient metabolism following an adverse in utero environment and the modulation of later life insulin sensitivity. Nutrients (2015) 0.81
Metabolic adaptations to short-term every-other-day feeding in long-living Ames dwarf mice. Exp Gerontol (2013) 0.80
Lipid exposure elicits differential responses in gene expression and DNA methylation in primary human skeletal muscle cells from severely obese women. Physiol Genomics (2015) 0.79
The molecular and metabolic influence of long term agmatine consumption. J Biol Chem (2014) 0.78
Pentoxifylline ameliorates non-alcoholic fatty liver disease in hyperglycaemic and dyslipidaemic mice by upregulating fatty acid β-oxidation. Sci Rep (2016) 0.78
IL-15 Mediates Mitochondrial Activity through a PPARδ-Dependent-PPARα-Independent Mechanism in Skeletal Muscle Cells. PPAR Res (2016) 0.76
Increased 24-hour ad libitum food intake is associated with lower plasma irisin concentrations the following morning in adult humans. Appetite (2015) 0.76
Maternal Engineered Nanomaterial Exposure Disrupts Progeny Cardiac Function and Bioenergetics. Am J Physiol Heart Circ Physiol (2016) 0.75
Resistive Training and Molecular Regulators of Vascular-Metabolic Risk in Chronic Stroke. J Stroke Cerebrovasc Dis (2016) 0.75
The Human Skeletal Muscle Transcriptome in Response to Oral Shilajit Supplementation. J Med Food (2016) 0.75
Exercise training-induced improvement in skeletal muscle PGC-1α-mediated fat metabolism is independent of dietary glycemic index. Obesity (Silver Spring) (2017) 0.75
Overexpression of PGC-1α Increases Peroxisomal and Mitochondrial Fatty Acid Oxidation in Human Primary Myotubes. Am J Physiol Endocrinol Metab (2017) 0.75
PPARδ preserves a high resistance to fatigue in the mouse medial gastrocnemius after spinal cord transection. Muscle Nerve (2015) 0.75
Peroxisome Proliferator-Activated Receptor -β/δ, -γ Agonists and Resveratrol Modulate Hypoxia Induced Changes in Nuclear Receptor Activators of Muscle Oxidative Metabolism. PPAR Res (2010) 0.75
Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance. Nat Med (2004) 5.04
Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control. J Biol Chem (2009) 2.28
Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility. Cell Metab (2012) 2.11
Adipose acyl-CoA synthetase-1 directs fatty acids toward beta-oxidation and is required for cold thermogenesis. Cell Metab (2010) 2.00
Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption. Diabetes (2010) 1.97
Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs Fatty Acid oxidation and induces cardiac hypertrophy. Mol Cell Biol (2011) 1.55
Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition. J Biol Chem (2009) 1.54
SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase. Mol Cell (2013) 1.52
Metabolic profiling of PPARalpha-/- mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation. FASEB J (2008) 1.45
Evidence of a malonyl-CoA-insensitive carnitine palmitoyltransferase I activity in red skeletal muscle. Am J Physiol Endocrinol Metab (2002) 1.24
Contraction of insulin-resistant muscle normalizes insulin action in association with increased mitochondrial activity and fatty acid catabolism. Am J Physiol Cell Physiol (2006) 1.21
Receptor-selective coactivators as tools to define the biology of specific receptor-coactivator pairs. Mol Cell (2006) 1.18
Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase. Diabetes (2009) 1.16
Peroxisome proliferator-activated receptor-gamma coactivator-1alpha overexpression increases lipid oxidation in myocytes from extremely obese individuals. Diabetes (2010) 1.15
A lipidomics analysis of the relationship between dietary fatty acid composition and insulin sensitivity in young adults. Diabetes (2012) 1.14
Obesity and lipid stress inhibit carnitine acetyltransferase activity. J Lipid Res (2014) 1.10
Dietary intake of palmitate and oleate has broad impact on systemic and tissue lipid profiles in humans. Am J Clin Nutr (2014) 1.05
Alterations in skeletal muscle fatty acid handling predisposes middle-aged mice to diet-induced insulin resistance. Diabetes (2010) 1.00
Lipid-induced metabolic dysfunction in skeletal muscle. Novartis Found Symp (2007) 0.99
Targeted metabolomics connects thioredoxin-interacting protein (TXNIP) to mitochondrial fuel selection and regulation of specific oxidoreductase enzymes in skeletal muscle. J Biol Chem (2014) 0.91
Substituting dietary monounsaturated fat for saturated fat is associated with increased daily physical activity and resting energy expenditure and with changes in mood. Am J Clin Nutr (2013) 0.90
Metabolic profiling of muscle contraction in lean compared with obese rodents. Am J Physiol Regul Integr Comp Physiol (2010) 0.89
Effect of short-term exercise training on insulin-stimulated PI 3-kinase activity in middle-aged men. Am J Physiol Endocrinol Metab (2002) 0.89
Re-patterning of skeletal muscle energy metabolism by fat storage-inducing transmembrane protein 2. J Biol Chem (2011) 0.87
Metabolite signatures of exercise training in human skeletal muscle relate to mitochondrial remodelling and cardiometabolic fitness. Diabetologia (2014) 0.84
Identification of a novel malonyl-CoA IC(50) for CPT-I: implications for predicting in vivo fatty acid oxidation rates. Biochem J (2012) 0.84
Ectopic lipid deposition and the metabolic profile of skeletal muscle in ovariectomized mice. Am J Physiol Regul Integr Comp Physiol (2012) 0.84
Increased insulin sensitivity in mice lacking collectrin, a downstream target of HNF-1alpha. Mol Endocrinol (2009) 0.81
Glucose uptake in muscle cell cultures from endurance-trained men. Med Sci Sports Exerc (2005) 0.79
Treatment with the 3-ketoacyl-CoA thiolase inhibitor trimetazidine does not exacerbate whole-body insulin resistance in obese mice. J Pharmacol Exp Ther (2014) 0.76
Time-dependent recovery from the effects of 6-hydroxydopamine lesions of the rat nucleus accumbens on cocaine self-administration and the levels of dopamine in microdialysates. Psychopharmacology (Berl) (2003) 0.76