Published in Am J Clin Nutr on January 15, 2014
Saturated Fat Versus Monounsaturated Fat and Insulin Action | NCT01612234
Dampened Mesolimbic Dopamine Function and Signaling by Saturated but not Monounsaturated Dietary Lipids. Neuropsychopharmacology (2015) 0.86
Valproate pretreatment protects pancreatic β-cells from palmitate-induced ER stress and apoptosis by inhibiting glycogen synthase kinase-3β. J Biomed Sci (2014) 0.83
Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism. Nat Commun (2016) 0.83
Effect of dietary Fatty acids on human lipoprotein metabolism: a comprehensive update. Nutrients (2015) 0.82
Plasma acylcarnitines and risk of cardiovascular disease: effect of Mediterranean diet interventions. Am J Clin Nutr (2016) 0.81
Lipidomic evidence that lowering the typical dietary palmitate to oleate ratio in humans decreases the leukocyte production of proinflammatory cytokines and muscle expression of redox-sensitive genes. J Nutr Biochem (2015) 0.81
Diet-Induced Obesity and Its Differential Impact on Periodontal Bone Loss. J Dent Res (2015) 0.80
Long-term dietary supplementation with saury oil attenuates metabolic abnormalities in mice fed a high-fat diet: combined beneficial effect of omega-3 fatty acids and long-chain monounsaturated fatty acids. Lipids Health Dis (2015) 0.78
Association of high dietary saturated fat intake and uncontrolled diabetes with constipation: evidence from the National Health and Nutrition Examination Survey. Neurogastroenterol Motil (2015) 0.78
Increased palmitate intake: higher acylcarnitine concentrations without impaired progression of β-oxidation. J Lipid Res (2015) 0.78
Arachidonic and oleic acid exert distinct effects on the DNA methylome. Epigenetics (2016) 0.77
Effects of canola and high-oleic-acid canola oils on abdominal fat mass in individuals with central obesity. Obesity (Silver Spring) (2016) 0.77
Role of cis-Monounsaturated Fatty Acids in the Prevention of Coronary Heart Disease. Curr Atheroscler Rep (2016) 0.77
Saturated fatty acids enhance TLR4 immune pathways in human trophoblasts. Hum Reprod (2015) 0.77
Diet-induced obesity impairs endometrial stromal cell decidualization: a potential role for impaired autophagy. Hum Reprod (2016) 0.77
Saturated Fatty Acids and Cardiovascular Disease: Replacements for Saturated Fat to Reduce Cardiovascular Risk. Healthcare (Basel) (2017) 0.76
Caryocar brasiliense oil improves cardiac function by increasing Serca2a/PLB ratio despite no significant changes in cardiovascular risk factors in rats. Lipids Health Dis (2017) 0.75
Dietary saturated fat and monounsaturated fat have reversible effects on brain function and the secretion of pro-inflammatory cytokines in young women. Metabolism (2016) 0.75
Dietary Fatty Acid Composition Modulates Obesity and Interacts with Obesity-Related Genes. Lipids (2017) 0.75
Heart disease and stroke statistics--2011 update: a report from the American Heart Association. Circulation (2010) 30.07
C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA (2001) 15.85
New methods for calculating metabolic rate with special reference to protein metabolism. J Physiol (1949) 13.56
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab (2009) 11.46
Diagnosis and classification of diabetes mellitus. Diabetes Care (2012) 9.03
Protein sensors for membrane sterols. Cell (2006) 8.62
International table of glycemic index and glycemic load values: 2002. Am J Clin Nutr (2002) 7.52
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat Immunol (2011) 6.53
Calculation of substrate oxidation rates in vivo from gaseous exchange. J Appl Physiol Respir Environ Exerc Physiol (1983) 6.45
Direct transesterification of all classes of lipids in a one-step reaction. J Lipid Res (1986) 6.42
Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency. J Biol Chem (2005) 4.30
Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry. Methods (2005) 3.42
Obesity-related derangements in metabolic regulation. Annu Rev Biochem (2006) 3.14
Identification of individuals with insulin resistance using routine clinical measurements. Diabetes (2005) 2.46
Nutrient modification of the innate immune response: a novel mechanism by which saturated fatty acids greatly amplify monocyte inflammation. Arterioscler Thromb Vasc Biol (2010) 2.42
Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways. J Biol Chem (2005) 2.33
Use of food quotients to predict respiratory quotients for the doubly-labelled water method of measuring energy expenditure. Hum Nutr Clin Nutr (1986) 2.22
Gender and C-reactive protein: data from the Multiethnic Study of Atherosclerosis (MESA) cohort. Am Heart J (2006) 2.22
Comparison of effects of dietary saturated, monounsaturated, and polyunsaturated fatty acids on plasma lipids and lipoproteins in man. J Lipid Res (1985) 2.11
Diets high in palmitic acid (16:0), lauric and myristic acids (12:0 + 14:0), or oleic acid (18:1) do not alter postprandial or fasting plasma homocysteine and inflammatory markers in healthy Malaysian adults. Am J Clin Nutr (2011) 2.04
Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cells. J Biol Chem (2008) 1.95
Comparison of monounsaturated fatty acids and carbohydrates for lowering plasma cholesterol. N Engl J Med (1986) 1.75
Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion. J Biol Chem (2006) 1.74
Inhibition of stearoyl-coenzyme A desaturase 1 dissociates insulin resistance and obesity from atherosclerosis. Circulation (2008) 1.71
The role of reducing intakes of saturated fat in the prevention of cardiovascular disease: where does the evidence stand in 2010? Am J Clin Nutr (2011) 1.66
Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress. Am J Physiol Endocrinol Metab (2010) 1.63
The Mediterranean diet: science and practice. Public Health Nutr (2006) 1.61
Increasing dietary palmitic acid decreases fat oxidation and daily energy expenditure. Am J Clin Nutr (2005) 1.16
Dietary fatty acids and the regulation of plasma low density lipoprotein cholesterol concentrations. J Nutr (1998) 1.16
A lipidomics analysis of the relationship between dietary fatty acid composition and insulin sensitivity in young adults. Diabetes (2012) 1.14
Short-term effects of dietary fatty acids on muscle lipid composition and serum acylcarnitine profile in human subjects. Obesity (Silver Spring) (2010) 1.09
Lipidomics as a tool for the study of lipoprotein metabolism. Curr Atheroscler Rep (2010) 1.01
Comparison of monounsaturated fat with carbohydrates as a replacement for saturated fat in subjects with a high metabolic risk profile: studies in the fasting and postprandial states. Am J Clin Nutr (2007) 1.01
Ovariectomy in mice decreases lipid metabolism-related gene expression in adipose tissue and skeletal muscle with increased body fat. J Nutr Sci Vitaminol (Tokyo) (2005) 0.99
Dietary interventions for metabolic syndrome: role of modifying dietary fats. Curr Diab Rep (2009) 0.99
Clinical relevance of the biochemical, metabolic, and genetic factors that influence low-density lipoprotein heterogeneity. Am J Cardiol (2002) 0.98
Dietary fat saturation effects on low-density-lipoprotein concentrations and metabolism in various animal models. Am J Clin Nutr (1997) 0.95
Methodology for adding glycemic index values to 24-hour recalls. Nutrition (2010) 0.93
Gender alters the effects of palmitate and oleate on fat oxidation and energy expenditure. Obesity (Silver Spring) (2008) 0.92
Dietary saturated fat/cholesterol, but not unsaturated fat or starch, induces C-reactive protein associated early atherosclerosis and ectopic fat deposition in diabetic pigs. Cardiovasc Diabetol (2011) 0.91
Substituting dietary monounsaturated fat for saturated fat is associated with increased daily physical activity and resting energy expenditure and with changes in mood. Am J Clin Nutr (2013) 0.90
Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity. Diabetes (2013) 0.89
Liver fatty acid composition in mice with or without nonalcoholic fatty liver disease. Lipids Health Dis (2011) 0.88
Effect of diet saturation on growth performance, carcass characteristics and fat quality of heavy pigs. Food Sci Technol Int (2010) 0.86
Comparative lipid and lipoprotein responses to solid-food diets and defined liquid-formula diets. Am J Clin Nutr (1999) 0.86
Effects of isoenergetic, low-fat diets on energy metabolism in lean and obese women. Am J Clin Nutr (1994) 0.85
A lipidomic analysis approach to evaluate the response to cholesterol-lowering food intake. Metabolomics (2011) 0.85
Changes in phosphatidylcholine fatty acid composition are associated with altered skeletal muscle insulin responsiveness in normal man. Metabolism (2000) 0.79
The minimum information about a genome sequence (MIGS) specification. Nat Biotechnol (2008) 31.04
Taverna: a tool for building and running workflows of services. Nucleic Acids Res (2006) 14.90
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metab (2008) 9.74
Bio-ontologies: current trends and future directions. Brief Bioinform (2006) 5.96
Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance. Nat Med (2004) 5.04
BioCatalogue: a universal catalogue of web services for the life sciences. Nucleic Acids Res (2010) 4.67
Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency. J Biol Chem (2005) 4.30
Genome-wide chromatin state transitions associated with developmental and environmental cues. Cell (2013) 3.83
Phase II trial of sorafenib in metastatic thyroid cancer. J Clin Oncol (2009) 3.73
State of the nation in data integration for bioinformatics. J Biomed Inform (2008) 3.60
Development of FuGO: an ontology for functional genomics investigations. OMICS (2006) 3.59
Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. Cell Metab (2005) 3.47
TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. Science (2006) 3.26
Metabolomics applied to diabetes research: moving from information to knowledge. Diabetes (2009) 2.68
Effects of obesity and bariatric surgery on airway hyperresponsiveness, asthma control, and inflammation. J Allergy Clin Immunol (2011) 2.53
Dissecting the in vivo metabolic potential of two human gut acetogens. J Biol Chem (2010) 2.42
Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control. J Biol Chem (2009) 2.28
The effect of weight loss and exercise training on flow-mediated dilatation in coronary heart disease: a randomized trial. Chest (2011) 2.15
Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility. Cell Metab (2012) 2.11
High-calorie-expenditure exercise: a new approach to cardiac rehabilitation for overweight coronary patients. Circulation (2009) 2.08
ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease. J Clin Invest (2004) 2.08
Adipose acyl-CoA synthetase-1 directs fatty acids toward beta-oxidation and is required for cold thermogenesis. Cell Metab (2010) 2.00
Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. Proc Natl Acad Sci U S A (2008) 1.97
Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption. Diabetes (2010) 1.97
Data curation + process curation=data integration + science. Brief Bioinform (2008) 1.82
Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs. J Biol Chem (2005) 1.74
A systematic strategy for large-scale analysis of genotype phenotype correlations: identification of candidate genes involved in African trypanosomiasis. Nucleic Acids Res (2007) 1.73
Severe acute malnutrition in childhood: hormonal and metabolic status at presentation, response to treatment, and predictors of mortality. J Clin Endocrinol Metab (2014) 1.64
Annotation of environmental OMICS data: application to the transcriptomics domain. OMICS (2006) 1.62
The Study of the Effects of Diet on Metabolism and Nutrition (STEDMAN) weight loss project: Rationale and design. Contemp Clin Trials (2005) 1.57
Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs Fatty Acid oxidation and induces cardiac hypertrophy. Mol Cell Biol (2011) 1.55
Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition. J Biol Chem (2009) 1.54
Ontology Design Patterns for bio-ontologies: a case study on the Cell Cycle Ontology. BMC Bioinformatics (2008) 1.54
A clinical description of extubation failure in patients with primary brain injury. Neurocrit Care (2011) 1.54
SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase. Mol Cell (2013) 1.52
Skeletal muscle adaptation to fatty acid depends on coordinated actions of the PPARs and PGC1 alpha: implications for metabolic disease. Appl Physiol Nutr Metab (2007) 1.46
Metabolic profiling of PPARalpha-/- mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation. FASEB J (2008) 1.45
The STEDMAN project: biophysical, biochemical and metabolic effects of a behavioral weight loss intervention during weight loss, maintenance, and regain. OMICS (2009) 1.43
Aerobic capacity in patients entering cardiac rehabilitation. Circulation (2006) 1.42
Understanding and using the meaning of statements in a bio-ontology: recasting the Gene Ontology in OWL. BMC Bioinformatics (2007) 1.38
Measuring the level of activity in community built bio-ontologies. J Biomed Inform (2012) 1.38
Differential gene expression profiling of short and long term denervated muscle. FASEB J (2005) 1.36
Subsarcolemmal and intermyofibrillar mitochondria play distinct roles in regulating skeletal muscle fatty acid metabolism. Am J Physiol Cell Physiol (2005) 1.36
Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA. PLoS Genet (2010) 1.34
BioGateway: a semantic systems biology tool for the life sciences. BMC Bioinformatics (2009) 1.32
Cancer associated fibroblasts stimulated by transforming growth factor beta1 (TGF-beta 1) increase invasion rate of tumor cells: a population study. Breast Cancer Res Treat (2007) 1.32
Elevation of IL-6 in the allergic asthmatic airway is independent of inflammation but associates with loss of central airway function. Respir Res (2010) 1.29
Cellular markers of muscle atrophy in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol (2009) 1.26
Evidence of a malonyl-CoA-insensitive carnitine palmitoyltransferase I activity in red skeletal muscle. Am J Physiol Endocrinol Metab (2002) 1.24
PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans. J Lipid Res (2012) 1.23
Contraction of insulin-resistant muscle normalizes insulin action in association with increased mitochondrial activity and fatty acid catabolism. Am J Physiol Cell Physiol (2006) 1.21
Receptor-selective coactivators as tools to define the biology of specific receptor-coactivator pairs. Mol Cell (2006) 1.18
Evidence that the Y chromosome influences autoimmune disease in male and female mice. Proc Natl Acad Sci U S A (2006) 1.18
Decreased limits of stability in response to postural perturbations in subjects with low back pain. Clin Biomech (Bristol, Avon) (2006) 1.18
A role for peroxisome proliferator-activated receptor γ coactivator-1 in the control of mitochondrial dynamics during postnatal cardiac growth. Circ Res (2013) 1.18
Increasing dietary palmitic acid decreases fat oxidation and daily energy expenditure. Am J Clin Nutr (2005) 1.16
Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase. Diabetes (2009) 1.16
A new case of human atransferrinemia with a previously undescribed mutation in the transferrin gene. Acta Haematol (2007) 1.16
Peroxisome proliferator-activated receptor-gamma coactivator-1alpha overexpression increases lipid oxidation in myocytes from extremely obese individuals. Diabetes (2010) 1.15
A lipidomics analysis of the relationship between dietary fatty acid composition and insulin sensitivity in young adults. Diabetes (2012) 1.14
Malignant-lesion segmentation using 4D co-occurrence texture analysis applied to dynamic contrast-enhanced magnetic resonance breast image data. J Magn Reson Imaging (2007) 1.14
Developing a kidney and urinary pathway knowledge base. J Biomed Semantics (2011) 1.13
Obesity and lipid stress inhibit carnitine acetyltransferase activity. J Lipid Res (2014) 1.10
Zinc-finger nuclease editing of human cxcr4 promotes HIV-1 CD4(+) T cell resistance and enrichment. Mol Ther (2012) 1.10
Populous: a tool for building OWL ontologies from templates. BMC Bioinformatics (2012) 1.10
Short-term effects of dietary fatty acids on muscle lipid composition and serum acylcarnitine profile in human subjects. Obesity (Silver Spring) (2010) 1.09
Distinct roles of specific fatty acids in cellular processes: implications for interpreting and reporting experiments. Am J Physiol Endocrinol Metab (2012) 1.09
Adding a little reality to building ontologies for biology. PLoS One (2010) 1.08
bioNerDS: exploring bioinformatics' database and software use through literature mining. BMC Bioinformatics (2013) 1.08
Metabolic remodeling of human skeletal myocytes by cocultured adipocytes depends on the lipolytic state of the system. Diabetes (2011) 1.05
Antibodies in action: role of human opsonins in killing Salmonella enterica serovar Typhi. Infect Immun (2011) 1.05
Cutting edge: the Y chromosome controls the age-dependent experimental allergic encephalomyelitis sexual dimorphism in SJL/J mice. J Immunol (2009) 1.03
The TriTryp phosphatome: analysis of the protein phosphatase catalytic domains. BMC Genomics (2007) 1.03
Logical Gene Ontology Annotations (GOAL): exploring gene ontology annotations with OWL. J Biomed Semantics (2012) 1.03
Lipid partitioning, incomplete fatty acid oxidation, and insulin signal transduction in primary human muscle cells: effects of severe obesity, fatty acid incubation, and fatty acid translocase/CD36 overexpression. J Clin Endocrinol Metab (2010) 1.03
ISPIDER Central: an integrated database web-server for proteomics. Nucleic Acids Res (2008) 1.03