Published in J Clin Endocrinol Metab on December 01, 2010
Acylcarnitines: reflecting or inflicting insulin resistance? Diabetes (2013) 1.54
Weight loss composition is one-fourth fat-free mass: a critical review and critique of this widely cited rule. Obes Rev (2014) 1.09
Postprandial changes in plasma acylcarnitine concentrations as markers of fatty acid flux in overweight and obesity. Metabolism (2011) 1.00
Daily Variation of Serum Acylcarnitines and Amino Acids. Metabolomics (2012) 0.92
Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial. PLoS One (2012) 0.85
Aerobic exercise training conserves insulin sensitivity for 1 yr following weight loss in overweight women. J Appl Physiol (1985) (2011) 0.82
The effects of age and dietary restriction on the tissue-specific metabolome of Drosophila. Aging Cell (2015) 0.82
Association between arterial stiffness and serum L-octanoylcarnitine and lactosylceramide in overweight middle-aged subjects: 3-year follow-up study. PLoS One (2015) 0.80
Sexual dimorphism in myocardial acylcarnitine and triglyceride metabolism. Biol Sex Differ (2016) 0.77
Analytes and Metabolites Associated with Muscle Quality in Young, Healthy Adults. Med Sci Sports Exerc (2015) 0.75
Effect of Exercise and Calorie Restriction on Tissue Acylcarnitines, Tissue Desaturase Indices, and Fat Accumulation in Diet-Induced Obese Rats. Sci Rep (2016) 0.75
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab (2009) 11.46
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metab (2008) 9.74
Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance. Nat Med (2004) 5.04
Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency. J Biol Chem (2005) 4.30
Calorie restriction increases muscle mitochondrial biogenesis in healthy humans. PLoS Med (2007) 3.92
Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women. Diabetes Care (2009) 3.69
Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men. Diabetologia (2010) 2.99
Effect of calorie restriction with or without exercise on insulin sensitivity, beta-cell function, fat cell size, and ectopic lipid in overweight subjects. Diabetes Care (2006) 2.86
Metabolomics applied to diabetes research: moving from information to knowledge. Diabetes (2009) 2.68
Metabolic and behavioral compensations in response to caloric restriction: implications for the maintenance of weight loss. PLoS One (2009) 2.56
Effect of calorie restriction with or without exercise on body composition and fat distribution. J Clin Endocrinol Metab (2007) 2.33
Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control. J Biol Chem (2009) 2.28
Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content. Diabetes (2008) 1.82
Caloric restriction alone and with exercise improves CVD risk in healthy non-obese individuals. Atherosclerosis (2008) 1.58
Skeletal muscle adaptation to fatty acid depends on coordinated actions of the PPARs and PGC1 alpha: implications for metabolic disease. Appl Physiol Nutr Metab (2007) 1.46
The STEDMAN project: biophysical, biochemical and metabolic effects of a behavioral weight loss intervention during weight loss, maintenance, and regain. OMICS (2009) 1.43
Skeletal muscle lipid oxidation and obesity: influence of weight loss and exercise. Am J Physiol Endocrinol Metab (2008) 1.29
Caloric restriction with or without exercise: the fitness versus fatness debate. Med Sci Sports Exerc (2010) 1.02
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab (2009) 11.46
Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med (2007) 9.83
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metab (2008) 9.74
Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science (2013) 8.81
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med (2011) 8.00
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature (2010) 6.48
Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial. JAMA (2009) 6.36
Mechanisms of disease:Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes. Nat Rev Mol Cell Biol (2008) 6.23
Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance. Nat Med (2004) 5.04
Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver. Cell Metab (2007) 4.51
Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency. J Biol Chem (2005) 4.30
The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins. Sci Transl Med (2011) 4.24
Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells. J Biol Chem (2003) 4.12
Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP. Cell (2005) 4.04
Calorie restriction increases muscle mitochondrial biogenesis in healthy humans. PLoS Med (2007) 3.92
Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. N Engl J Med (2016) 3.88
A guide to analysis of mouse energy metabolism. Nat Methods (2011) 3.82
Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women. Diabetes Care (2009) 3.69
Interventions to promote physical activity and dietary lifestyle changes for cardiovascular risk factor reduction in adults: a scientific statement from the American Heart Association. Circulation (2010) 3.63
Increased food energy supply is more than sufficient to explain the US epidemic of obesity. Am J Clin Nutr (2009) 3.59
Is it time to change the way we report and discuss weight loss? Obesity (Silver Spring) (2009) 3.57
Estimating the changes in energy flux that characterize the rise in obesity prevalence. Am J Clin Nutr (2009) 3.56
Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. Science (2012) 3.52
Racial differences in abdominal depot-specific adiposity in white and African American adults. Am J Clin Nutr (2009) 3.39
Death or hospitalization of patients on chronic hemodialysis is associated with a physician-based diagnosis of depression. Kidney Int (2008) 3.34
Heart failure and a controlled trial investigating outcomes of exercise training (HF-ACTION): design and rationale. Am Heart J (2007) 3.34
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome. Mol Cell (2011) 3.33
Lateral hypothalamic area deep brain stimulation for refractory obesity: a pilot study with preliminary data on safety, body weight, and energy metabolism. J Neurosurg (2013) 3.31
Effects of the amount of exercise on body weight, body composition, and measures of central obesity: STRRIDE--a randomized controlled study. Arch Intern Med (2004) 3.30
Leptin therapy in insulin-deficient type I diabetes. Proc Natl Acad Sci U S A (2010) 3.23
A futile metabolic cycle activated in adipocytes by antidiabetic agents. Nat Med (2002) 3.22
Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss. Sci Transl Med (2011) 3.20
Effect of the volume and intensity of exercise training on insulin sensitivity. J Appl Physiol (1985) (2003) 3.18
Multicenter validation of the diagnostic accuracy of a blood-based gene expression test for assessing obstructive coronary artery disease in nondiabetic patients. Ann Intern Med (2010) 3.17
Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease. Science (2008) 3.17
Obesity-related derangements in metabolic regulation. Annu Rev Biochem (2006) 3.14
Calorie restriction and aging: review of the literature and implications for studies in humans. Am J Clin Nutr (2003) 3.11
Hypothalamic CaMKK2 contributes to the regulation of energy balance. Cell Metab (2008) 3.04
Population approaches to improve diet, physical activity, and smoking habits: a scientific statement from the American Heart Association. Circulation (2012) 2.95
Effect of calorie restriction with or without exercise on insulin sensitivity, beta-cell function, fat cell size, and ectopic lipid in overweight subjects. Diabetes Care (2006) 2.86
Effects of exercise training on health status in patients with chronic heart failure: HF-ACTION randomized controlled trial. JAMA (2009) 2.83
Continuous electroencephalographic monitoring in critically ill patients: indications, limitations, and strategies. Crit Care Med (2013) 2.79
Body mass trajectories through adulthood: results from the National Longitudinal Survey of Youth 1979 Cohort (1981-2006). Int J Epidemiol (2010) 2.77
Metabolomics applied to diabetes research: moving from information to knowledge. Diabetes (2009) 2.68
Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling. PLoS Genet (2008) 2.63
Metabolic and behavioral compensations in response to caloric restriction: implications for the maintenance of weight loss. PLoS One (2009) 2.56
Main outcomes of the FRESH START trial: a sequentially tailored, diet and exercise mailed print intervention among breast and prostate cancer survivors. J Clin Oncol (2007) 2.50
Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice. Science (2013) 2.49
The relationship of waist circumference and BMI to visceral, subcutaneous, and total body fat: sex and race differences. Obesity (Silver Spring) (2010) 2.47
Genomic predictors of the maximal O₂ uptake response to standardized exercise training programs. J Appl Physiol (1985) (2010) 2.43
Dissecting the in vivo metabolic potential of two human gut acetogens. J Biol Chem (2010) 2.42
The effect of comorbid illness on receipt of cancer screening by older people. J Am Geriatr Soc (2002) 2.42
Coagulation and activation of inflammatory pathways in the development of functional decline and mortality in the elderly. Am J Med (2003) 2.41
Nitric oxide represses the Arabidopsis floral transition. Science (2004) 2.41
Inactivity, exercise, and visceral fat. STRRIDE: a randomized, controlled study of exercise intensity and amount. J Appl Physiol (1985) (2005) 2.38
Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events. Circ Cardiovasc Genet (2010) 2.34
Validation study of energy expenditure and intake during calorie restriction using doubly labeled water and changes in body composition. Am J Clin Nutr (2007) 2.33
Effect of calorie restriction with or without exercise on body composition and fat distribution. J Clin Endocrinol Metab (2007) 2.33
Presence and severity of intensive care unit-acquired paresis at time of awakening are associated with increased intensive care unit and hospital mortality. Crit Care Med (2009) 2.31
Factors related to morbidity and mortality in patients with chronic heart failure with systolic dysfunction: the HF-ACTION predictive risk score model. Circ Heart Fail (2011) 2.28
Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control. J Biol Chem (2009) 2.28
Comparison of aerobic versus resistance exercise training effects on metabolic syndrome (from the Studies of a Targeted Risk Reduction Intervention Through Defined Exercise - STRRIDE-AT/RT). Am J Cardiol (2011) 2.28
Prospective evaluation of pain and analgesic use following major elective intracranial surgery. J Neurosurg (2007) 2.26
Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta. J Biol Chem (2002) 2.25