Published in Toxicon on October 24, 2007
Purification, molecular cloning and functional characterization of HelaTx1 (Heterometrus laoticus): the first member of a new κ-KTX subfamily. Biochem Pharmacol (2012) 0.86
Towards stereochemical control: A short formal enantioselective total synthesis of pumiliotoxins 251D and 237A. Beilstein J Org Chem (2013) 0.75
Chronic administration of anticholinergics in rats induces a shift from muscarinic to purinergic transmission in the bladder wall. Eur Urol (2013) 2.15
Inactivation in HCN channels results from reclosure of the activation gate: desensitization to voltage. Neuron (2004) 1.66
Myasthenic syndrome caused by mutation of the SCN4A sodium channel. Proc Natl Acad Sci U S A (2003) 1.50
Evolutionary origin of inhibitor cystine knot peptides. FASEB J (2003) 1.31
Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes. Mol Pharmacol (2005) 1.31
An overview of toxins and genes from the venom of the Asian scorpion Buthus martensi Karsch. Toxicon (2002) 1.29
Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC). J Biol Chem (2013) 1.22
Crystal structures of a cysteine-modified mutant in loop D of acetylcholine-binding protein. J Biol Chem (2010) 1.18
kappa-Hefutoxin1, a novel toxin from the scorpion Heterometrus fulvipes with unique structure and function. Importance of the functional diad in potassium channel selectivity. J Biol Chem (2002) 1.17
Neurotoxins and their binding areas on voltage-gated sodium channels. Front Pharmacol (2011) 1.15
The differential preference of scorpion alpha-toxins for insect or mammalian sodium channels: implications for improved insect control. Toxicon (2006) 1.12
Voltage-gated sodium channel modulation by scorpion alpha-toxins. Toxicon (2006) 1.12
Animal peptides targeting voltage-activated sodium channels. Curr Pharm Des (2008) 1.11
Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa. Eur J Biochem (2002) 1.09
Potent modulation of the voltage-gated sodium channel Nav1.7 by OD1, a toxin from the scorpion Odonthobuthus doriae. Mol Pharmacol (2006) 1.08
Biological activities of aqueous and organic extracts from tropical marine sponges. Mar Drugs (2010) 1.00
Function and solution structure of hainantoxin-I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana. FEBS Lett (2003) 1.00
Jellyfish and other cnidarian envenomations cause pain by affecting TRPV1 channels. FEBS Lett (2006) 1.00
Adaptive evolution of scorpion sodium channel toxins. J Mol Evol (2004) 0.99
A bifunctional sea anemone peptide with Kunitz type protease and potassium channel inhibiting properties. Biochem Pharmacol (2011) 0.98
Gambierol, a toxin produced by the dinoflagellate Gambierdiscus toxicus, is a potent blocker of voltage-gated potassium channels. Toxicon (2008) 0.97
A case of palytoxin poisoning due to contact with zoanthid corals through a skin injury. Toxicon (2008) 0.97
OdK2, a Kv1.3 channel-selective toxin from the venom of the Iranian scorpion Odonthobuthus doriae. Toxicon (2008) 0.96
Evolutionary epitopes of Hsp90 and p23: implications for their interaction. FASEB J (2004) 0.96
An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis. Biochem J (2005) 0.96
Solution structure and alanine scan of a spider toxin that affects the activation of mammalian voltage-gated sodium channels. J Biol Chem (2006) 0.96
OD1, the first toxin isolated from the venom of the scorpion Odonthobuthus doriae active on voltage-gated Na+ channels. FEBS Lett (2005) 0.96
The first potassium channel toxin from the venom of the Iranian scorpion Odonthobuthus doriae. FEBS Lett (2006) 0.95
Sea anemone venom as a source of insecticidal peptides acting on voltage-gated Na+ channels. Toxicon (2006) 0.94
Tetrodotoxin and its analogue 6-epitetrodotoxin in newts (Triturus spp.; Urodela, Salamandridae) from southern Germany. Toxicon (2007) 0.94
Turret and pore block of K+ channels: what is the difference? Trends Pharmacol Sci (2003) 0.93
Resistance to tyrosine kinase inhibitors: calling on extra forces. Drug Resist Updat (2005) 0.93
BmBKTx1, a novel Ca2+-activated K+ channel blocker purified from the Asian scorpion Buthus martensi Karsch. J Biol Chem (2004) 0.92
Experimental conversion of a defensin into a neurotoxin: implications for origin of toxic function. Mol Biol Evol (2014) 0.92
Synthesis, solution structure, and phylum selectivity of a spider delta-toxin that slows inactivation of specific voltage-gated sodium channel subtypes. J Biol Chem (2009) 0.91
'Venomics' or : The venomous systems genome project. Toxicon (2006) 0.90
An insecticidal peptide from the theraposid Brachypelma smithi spider venom reveals common molecular features among spider species from different genera. Peptides (2008) 0.89
Evolutionary trace analysis of scorpion toxins specific for K-channels. Proteins (2004) 0.89
Evolutionary diversification of Mesobuthus α-scorpion toxins affecting sodium channels. Mol Cell Proteomics (2011) 0.89
Purification, characterization and biosynthesis of parabutoxin 3, a component of Parabuthus transvaalicus venom. Eur J Biochem (2002) 0.89
A natural point mutation changes both target selectivity and mechanism of action of sea anemone toxins. FASEB J (2012) 0.89
Molecular basis of the mammalian potency of the scorpion alpha-like toxin, BmK M1. FASEB J (2005) 0.89
Distribution of tetrodotoxin in the body of the blue-ringed octopus (Hapalochlaena maculosa). Toxicon (2006) 0.88
Importance of position 8 in μ-conotoxin KIIIA for voltage-gated sodium channel selectivity. FEBS J (2011) 0.88
Jingzhaotoxin-I, a novel spider neurotoxin preferentially inhibiting cardiac sodium channel inactivation. J Biol Chem (2004) 0.88
Molecular diversity and functional evolution of scorpion potassium channel toxins. Mol Cell Proteomics (2010) 0.88
Importance of the conserved aromatic residues in the scorpion alpha-like toxin BmK M1: the hydrophobic surface region revisited. J Biol Chem (2003) 0.88
Crotamine pharmacology revisited: novel insights based on the inhibition of KV channels. Mol Pharmacol (2012) 0.87
TRPV1 as a key determinant in ciguatera and neurotoxic shellfish poisoning. Biochem Biophys Res Commun (2007) 0.87
Structural basis for the voltage-gated Na+ channel selectivity of the scorpion alpha-like toxin BmK M1. J Mol Biol (2005) 0.87
The sea anemone Bunodosoma granulifera contains surprisingly efficacious and potent insect-selective toxins. FEBS Lett (2002) 0.86
Early exercise training after myocardial infarction prevents contractile but not electrical remodelling or hypertrophy. Cardiovasc Res (2009) 0.86
Insecticidal peptides from the theraposid spider Brachypelma albiceps: an NMR-based model of Ba2. Biochim Biophys Acta (2009) 0.86
Two new scorpion toxins that target voltage-gated Ca2+ and Na+ channels. Biochem Biophys Res Commun (2002) 0.86
Molecular diversity of the telson and venom components from Pandinus cavimanus (Scorpionidae Latreille 1802): transcriptome, venomics and function. Proteomics (2012) 0.86
Purification, molecular cloning and functional characterization of HelaTx1 (Heterometrus laoticus): the first member of a new κ-KTX subfamily. Biochem Pharmacol (2012) 0.86
Variability of tetrodotoxin and of its analogues in the red-spotted newt, Notophthalmus viridescens (Amphibia: Urodela: Salamandridae). Toxicon (2011) 0.85
A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors. Br J Pharmacol (2012) 0.85
A polyether biotoxin binding site on the lipid-exposed face of the pore domain of Kv channels revealed by the marine toxin gambierol. Proc Natl Acad Sci U S A (2009) 0.85
Unique bell-shaped voltage-dependent modulation of Na+ channel gating by novel insect-selective toxins from the spider Agelena orientalis. J Biol Chem (2010) 0.85
The new kappa-KTx 2.5 from the scorpion Opisthacanthus cayaporum. Peptides (2011) 0.85
Characterization of Amm VIII from Androctonus mauretanicus mauretanicus: a new scorpion toxin that discriminates between neuronal and skeletal sodium channels. Biochem J (2003) 0.85
Design of bioactive peptides from naturally occurring μ-conotoxin structures. J Biol Chem (2012) 0.85
Assignment of voltage-gated potassium channel blocking activity to kappa-KTx1.3, a non-toxic homologue of kappa-hefutoxin-1, from Heterometrus spinifer venom. Biochem Pharmacol (2004) 0.84
Phylogeography of Australia's king brown snake (Pseudechis australis) reveals Pliocene divergence and Pleistocene dispersal of a top predator. Naturwissenschaften (2005) 0.84
Venom components from Citharischius crawshayi spider (Family Theraphosidae): exploring transcriptome, venomics, and function. Cell Mol Life Sci (2010) 0.84
A novel conotoxin from Conus betulinus, kappa-BtX, unique in cysteine pattern and in function as a specific BK channel modulator. J Biol Chem (2003) 0.84
An aqueous extract of the marine sponge Ectyoplasia ferox stimulates L-type Ca2+-current by direct interaction with the Cav1.2 subunit. Naunyn Schmiedebergs Arch Pharmacol (2004) 0.83
Investigation of the relationship between the structure and function of Ts2, a neurotoxin from Tityus serrulatus venom. FEBS J (2012) 0.83
Detection of hemolytic bacteria from Palythoa caribaeorum (Cnidaria, Zoantharia) using a novel palytoxin-screening assay. Antonie Van Leeuwenhoek (2009) 0.83
Molecular divergence of two orthologous scorpion toxins affecting potassium channels. Comp Biochem Physiol A Mol Integr Physiol (2011) 0.83
Snake fangs from the Lower Miocene of Germany: evolutionary stability of perfect weapons. Naturwissenschaften (2006) 0.82
Voltage-gated sodium channel isoform-specific effects of pompilidotoxins. FEBS J (2010) 0.82
Multiple actions of phi-LITX-Lw1a on ryanodine receptors reveal a functional link between scorpion DDH and ICK toxins. Proc Natl Acad Sci U S A (2013) 0.82
BmTx3, a scorpion toxin with two putative functional faces separately active on A-type K+ and HERG currents. Biochem J (2004) 0.82
Comment on "Impaired respiratory and body temperature control upon acute serotonergic neuron inhibition". Science (2012) 0.82
Direct cDNA cloning of novel conopeptide precursors of the O-superfamily. Peptides (2005) 0.82
New "Birtoxin analogs" from Androctonus australis venom. Biochem Biophys Res Commun (2005) 0.82
Novel potassium channel blocker venom peptides from Mesobuthus gibbosus (Scorpiones: Buthidae). Toxicon (2012) 0.82
Biochemical and electrophysiological characterization of two sea anemone type 1 potassium toxins from a geographically distant population of Bunodosoma caissarum. Mar Drugs (2013) 0.82
Novel conopeptides of the I-superfamily occur in several clades of cone snails. Toxicon (2004) 0.82
Differential effects of five 'classical' scorpion beta-toxins on rNav1.2a and DmNav1 provide clues on species-selectivity. Toxicol Appl Pharmacol (2006) 0.82
MeuTXKbeta1, a scorpion venom-derived two-domain potassium channel toxin-like peptide with cytolytic activity. Biochim Biophys Acta (2010) 0.82
Occurrence of 11-oxotetrodotoxin in the red-spotted newt, Notophthalmus viridescens, and further studies on the levels of tetrodotoxin and its analogues in the newt's efts. Toxicon (2003) 0.82
The poison Dart frog's batrachotoxin modulates Nav1.8. FEBS Lett (2004) 0.81
Structure-function elucidation of a new α-conotoxin, Lo1a, from Conus longurionis. J Biol Chem (2014) 0.81
The depressant scorpion neurotoxin LqqIT2 selectively modulates the insect voltage-gated sodium channel. Toxicon (2005) 0.81
A novel toxin from the venom of the scorpion Tityus trivittatus, is the first member of a new alpha-KTX subfamily. FEBS Lett (2006) 0.81
A new Kaliotoxin selective towards Kv1.3 and Kv1.2 but not Kv1.1 channels expressed in oocytes. Biochem Biophys Res Commun (2008) 0.81