Published in Science on December 07, 2007
The Corynebacterium diphtheriae shaft pilin SpaA is built of tandem Ig-like modules with stabilizing isopeptide and disulfide bonds. Proc Natl Acad Sci U S A (2009) 1.79
The molecular switch that activates the cell wall anchoring step of pilus assembly in gram-positive bacteria. Proc Natl Acad Sci U S A (2008) 1.75
Intramolecular isopeptide bonds give thermodynamic and proteolytic stability to the major pilin protein of Streptococcus pyogenes. J Biol Chem (2009) 1.45
Isopeptide bonds block the mechanical extension of pili in pathogenic Streptococcus pyogenes. J Biol Chem (2010) 1.38
Crystal structure of the minor pilin FctB reveals determinants of Group A streptococcal pilus anchoring. J Biol Chem (2010) 1.16
Autocatalytic intramolecular isopeptide bond formation in gram-positive bacterial pili: a QM/MM simulation. J Am Chem Soc (2010) 0.97
Mutational analysis of a conserved glutamic acid required for self-catalyzed cross-linking of bacteriophage HK97 capsids. J Virol (2008) 0.94
Structure of the full-length major pilin from Streptococcus pneumoniae: implications for isopeptide bond formation in gram-positive bacterial pili. PLoS One (2011) 0.93
Structure and assembly of group B streptococcus pilus 2b backbone protein. PLoS One (2015) 0.80
CnaA domains in bacterial pili are efficient dissipaters of large mechanical shocks. Proc Natl Acad Sci U S A (2016) 0.77
Unusually high mechanical stability of bacterial adhesin extender domains having calcium clamps. PLoS One (2017) 0.75
A comparative genome analysis identifies distinct sorting pathways in gram-positive bacteria. Infect Immun (2004) 2.04
Functionally distinct NEAT (NEAr Transporter) domains within the Staphylococcus aureus IsdH/HarA protein extract heme from methemoglobin. J Biol Chem (2008) 1.39
Solution structure of the NEAT (NEAr Transporter) domain from IsdH/HarA: the human hemoglobin receptor in Staphylococcus aureus. J Mol Biol (2006) 1.37
Sortase enzymes in Gram-positive bacteria. Mol Microbiol (2011) 1.37
The structure of the Staphylococcus aureus sortase-substrate complex reveals how the universally conserved LPXTG sorting signal is recognized. J Biol Chem (2009) 1.37
Crystal structure of the excisionase-DNA complex from bacteriophage lambda. J Mol Biol (2004) 1.31
The IsdC protein from Staphylococcus aureus uses a flexible binding pocket to capture heme. J Biol Chem (2008) 1.30
Arm-site binding by lambda -integrase: solution structure and functional characterization of its amino-terminal domain. Proc Natl Acad Sci U S A (2002) 1.23
Staphylococcus aureus Sortase A transpeptidase. Calcium promotes sorting signal binding by altering the mobility and structure of an active site loop. J Biol Chem (2005) 1.21
Structure of the dimerization domain of DiGeorge critical region 8. Protein Sci (2010) 1.16
Transient weak protein-protein complexes transfer heme across the cell wall of Staphylococcus aureus. J Am Chem Soc (2011) 1.13
Identification and solution structure of a highly conserved C-terminal domain within ORF1p required for retrotransposition of long interspersed nuclear element-1. J Biol Chem (2007) 1.12
Discovery and structure-activity relationship analysis of Staphylococcus aureus sortase A inhibitors. Bioorg Med Chem (2009) 1.12
Structural basis for hemoglobin capture by Staphylococcus aureus cell-surface protein, IsdH. J Biol Chem (2011) 1.11
Structure of the cooperative Xis-DNA complex reveals a micronucleoprotein filament that regulates phage lambda intasome assembly. Proc Natl Acad Sci U S A (2007) 1.11
The structure of the Dead ringer-DNA complex reveals how AT-rich interaction domains (ARIDs) recognize DNA. EMBO J (2002) 1.08
Regulation of directionality in bacteriophage lambda site-specific recombination: structure of the Xis protein. J Mol Biol (2002) 1.08
Fis targets assembly of the Xis nucleoprotein filament to promote excisive recombination by phage lambda. J Mol Biol (2007) 1.06
Identification of the lambda integrase surface that interacts with Xis reveals a residue that is also critical for Int dimer formation. Proc Natl Acad Sci U S A (2003) 1.03
Identifying and characterizing a functional HIV-1 reverse transcriptase-binding site on integrase. J Biol Chem (2009) 1.03
Localization and mutagenesis of the sorting signal binding site on sortase A from Staphylococcus aureus. FEBS Lett (2004) 1.03
The structure of the excisionase (Xis) protein from conjugative transposon Tn916 provides insights into the regulation of heterobivalent tyrosine recombinases. J Mol Biol (2005) 0.98
Staphylococcus aureus uses a novel multidomain receptor to break apart human hemoglobin and steal its heme. J Biol Chem (2012) 0.97
NMR structure of the amino-terminal domain of the lambda integrase protein in complex with DNA: immobilization of a flexible tail facilitates beta-sheet recognition of the major groove. J Mol Biol (2009) 0.93
Sortase from Staphylococcus aureus does not contain a thiolate-imidazolium ion pair in its active site. J Biol Chem (2003) 0.93
Assembly of minicellulosomes on the surface of Bacillus subtilis. Appl Environ Microbiol (2011) 0.92
The Sortase A enzyme that attaches proteins to the cell wall of Bacillus anthracis contains an unusual active site architecture. J Biol Chem (2010) 0.91
Structure of the hemoglobin-IsdH complex reveals the molecular basis of iron capture by Staphylococcus aureus. J Biol Chem (2014) 0.90
Discovery of Staphylococcus aureus sortase A inhibitors using virtual screening and the relaxed complex scheme. Chem Biol Drug Des (2013) 0.89
Synthesis of (2R,3S) 3-amino-4-mercapto-2-butanol, a threonine analogue for covalent inhibition of sortases. Bioorg Med Chem Lett (2005) 0.88
Crystallization, dehydration and preliminary X-ray analysis of excisionase (Xis) proteins cooperatively bound to DNA. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.87
The binding mechanism, multiple binding modes, and allosteric regulation of Staphylococcus aureus Sortase A probed by molecular dynamics simulations. Protein Sci (2012) 0.86
Xis protein binding to the left arm stimulates excision of conjugative transposon Tn916. J Bacteriol (2002) 0.86
Structural and computational studies of the Staphylococcus aureus sortase B-substrate complex reveal a substrate-stabilized oxyanion hole. J Biol Chem (2014) 0.85
Axial ligand replacement mechanism in heme transfer from streptococcal heme-binding protein Shp to HtsA of the HtsABC transporter. Biochemistry (2013) 0.83
Anthrax toxin receptor 1/tumor endothelial marker 8: mutation of conserved inserted domain residues overrides cytosolic control of protective antigen binding. Biochemistry (2010) 0.82
Retracted Recombinant Bacillus subtilis that grows on untreated plant biomass. Appl Environ Microbiol (2012) 0.82
Energetics of sequence-specific protein-DNA association: binding of integrase Tn916 to its target DNA. Biochemistry (2003) 0.81
Energetics of sequence-specific protein-DNA association: conformational stability of the DNA binding domain of integrase Tn916 and its cognate DNA duplex. Biochemistry (2003) 0.81
Backbone 1H, 13C and 15N resonance assignments of the 39 kDa staphylococcal hemoglobin receptor IsdH. Biomol NMR Assign (2011) 0.80
NMR resonance assignments of the NEAT (NEAr Transporter) domain from the Staphylococcus aureus IsdH protein. J Biomol NMR (2005) 0.80
Crystallization and preliminary X-ray crystallographic analysis of the excisionase-DNA complex from bacteriophage lambda. Acta Crystallogr D Biol Crystallogr (2003) 0.79
A heteronuclear zero quantum coherence Nz-exchange experiment that resolves resonance overlap and its application to measure the rates of heme binding to the IsdC protein. J Am Chem Soc (2010) 0.79
Compensating increases in protein backbone flexibility occur when the Dead ringer AT-rich interaction domain (ARID) binds DNA: a nitrogen-15 relaxation study. Protein Sci (2005) 0.79
Site-directed spin labeling electron paramagnetic resonance study of the ORF1 protein from a mouse L1 retrotransposon. Protein Sci (2011) 0.79
A sweet new role for LCP enzymes in protein glycosylation. Mol Microbiol (2014) 0.77
Solution structure of the sortase required for efficient production of infectious Bacillus anthracis spores. Biochemistry (2012) 0.77
Preparation and optimization of protein-DNA complexes suitable for detailed NMR studies. Methods Mol Biol (2012) 0.75
Correction: Energetics underlying hemin extraction from human hemoglobin by . J Biol Chem (2020) 0.75