Published in PLoS One on July 08, 2011
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The pilin protein FimP from Actinomyces oris: crystal structure and sequence analyses. PLoS One (2012) 0.85
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Structural basis of pilus anchoring by the ancillary pilin RrgC of Streptococcus pneumoniae. J Biol Chem (2014) 0.85
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Platelet endothelial cell adhesion molecule-1, a putative receptor for the adhesion of Streptococcus pneumoniae to the vascular endothelium of the blood-brain barrier. Infect Immun (2014) 0.81
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A structural snapshot of type II pilus formation in Streptococcus pneumoniae. J Biol Chem (2015) 0.77
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RrgA is a pilus-associated adhesin in Streptococcus pneumoniae. Mol Microbiol (2007) 2.01
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Novel fold and assembly of the repetitive B region of the Staphylococcus aureus collagen-binding surface protein. Structure (2000) 1.87
The Corynebacterium diphtheriae shaft pilin SpaA is built of tandem Ig-like modules with stabilizing isopeptide and disulfide bonds. Proc Natl Acad Sci U S A (2009) 1.79
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An IgG-like domain in the minor pilin GBS52 of Streptococcus agalactiae mediates lung epithelial cell adhesion. Structure (2007) 1.64
Amide bonds assemble pili on the surface of bacilli. Proc Natl Acad Sci U S A (2008) 1.53
Intramolecular isopeptide bonds give thermodynamic and proteolytic stability to the major pilin protein of Streptococcus pyogenes. J Biol Chem (2009) 1.45
Isopeptide bonds block the mechanical extension of pili in pathogenic Streptococcus pyogenes. J Biol Chem (2010) 1.38
Intramolecular isopeptide bonds: protein crosslinks built for stress? Trends Biochem Sci (2010) 1.31
Intramolecular amide bonds stabilize pili on the surface of bacilli. Proc Natl Acad Sci U S A (2009) 1.31
Molecular architecture of Streptococcus pneumoniae TIGR4 pili. EMBO J (2009) 1.29
Sortase D forms the covalent bond that links BcpB to the tip of Bacillus cereus pili. J Biol Chem (2009) 1.25
A highly unusual thioester bond in a pilus adhesin is required for efficient host cell interaction. J Biol Chem (2010) 1.25
Crystal structure of the minor pilin FctB reveals determinants of Group A streptococcal pilus anchoring. J Biol Chem (2010) 1.16
Supramolecular organization of the repetitive backbone unit of the Streptococcus pneumoniae pilus. PLoS One (2010) 1.11
A model for group B Streptococcus pilus type 1: the structure of a 35-kDa C-terminal fragment of the major pilin GBS80. J Mol Biol (2011) 1.06
Stability and assembly of pilus subunits of Streptococcus pneumoniae. J Biol Chem (2010) 1.02
Biochemistry. How some pili pull. Science (2007) 0.98
Isopeptide bonds in bacterial pili and their characterization by X-ray crystallography and mass spectrometry. Biopolymers (2009) 0.95
Sortases make pili from three ingredients. Proc Natl Acad Sci U S A (2008) 0.94
Structural and functional characterization of the Streptococcus pneumoniae RrgB pilus backbone D1 domain. J Biol Chem (2011) 0.85
Stabilizing isopeptide bonds revealed in gram-positive bacterial pilus structure. Science (2007) 4.10
The Corynebacterium diphtheriae shaft pilin SpaA is built of tandem Ig-like modules with stabilizing isopeptide and disulfide bonds. Proc Natl Acad Sci U S A (2009) 1.79
Distant structural homology leads to the functional characterization of an archaeal PIN domain as an exonuclease. J Biol Chem (2004) 1.74
A flexible and economical medium-throughput strategy for protein production and crystallization. Acta Crystallogr D Biol Crystallogr (2005) 1.67
The crystal structure of aminoglycoside-3'-phosphotransferase-IIa, an enzyme responsible for antibiotic resistance. J Mol Biol (2003) 1.65
Intramolecular isopeptide bonds give thermodynamic and proteolytic stability to the major pilin protein of Streptococcus pyogenes. J Biol Chem (2009) 1.45
Dealing with iron: common structural principles in proteins that transport iron and heme. Proc Natl Acad Sci U S A (2003) 1.44
Crystal structure of LeuA from Mycobacterium tuberculosis, a key enzyme in leucine biosynthesis. Proc Natl Acad Sci U S A (2004) 1.44
Intramolecular isopeptide bonds: protein crosslinks built for stress? Trends Biochem Sci (2010) 1.31
The TB structural genomics consortium: providing a structural foundation for drug discovery. Curr Drug Targets Infect Disord (2002) 1.28
The Three-dimensional structure of a superantigen-like protein, SET3, from a pathogenicity island of the Staphylococcus aureus genome. J Biol Chem (2002) 1.28
The crystal structures of substrate and nucleotide complexes of Enterococcus faecium aminoglycoside-2''-phosphotransferase-IIa [APH(2'')-IIa] provide insights into substrate selectivity in the APH(2'') subfamily. J Bacteriol (2009) 1.27
Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism. Proc Natl Acad Sci U S A (2006) 1.27
Structure and assembly of Gram-positive bacterial pili: unique covalent polymers. Curr Opin Struct Biol (2012) 1.21
Aminoglycoside antibiotic resistance by enzymatic deactivation. Curr Drug Targets Infect Disord (2002) 1.17
Crystal structure of the minor pilin FctB reveals determinants of Group A streptococcal pilus anchoring. J Biol Chem (2010) 1.16
A new Gateway vector and expression protocol for fast and efficient recombinant protein expression in Mycobacterium smegmatis. Protein Expr Purif (2007) 1.14
Structure and inhibition of the human cell cycle checkpoint kinase, Wee1A kinase: an atypical tyrosine kinase with a key role in CDK1 regulation. Structure (2005) 1.13
Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of coenzyme and substrate binding. J Biol Chem (2008) 1.12
Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys peroxiredoxin. J Mol Biol (2005) 1.11
The structure of MbtI from Mycobacterium tuberculosis, the first enzyme in the biosynthesis of the siderophore mycobactin, reveals it to be a salicylate synthase. J Bacteriol (2006) 1.11
Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis expression system. Protein Expr Purif (2007) 1.10
The crystal structure of Rv1347c, a putative antibiotic resistance protein from Mycobacterium tuberculosis, reveals a GCN5-related fold and suggests an alternative function in siderophore biosynthesis. J Biol Chem (2005) 1.08
The crystal structure of staphylococcal superantigen-like protein 11 in complex with sialyl Lewis X reveals the mechanism for cell binding and immune inhibition. Mol Microbiol (2007) 1.07
Crystal structure of PAE0151 from Pyrobaculum aerophilum, a PIN-domain (VapC) protein from a toxin-antitoxin operon. Proteins (2008) 1.07
Crystal structure of MshB from Mycobacterium tuberculosis, a deacetylase involved in mycothiol biosynthesis. J Mol Biol (2004) 1.04
The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II enzymes. J Mol Biol (2005) 1.04
Lactoferrin is a potent regulator of bone cell activity and increases bone formation in vivo. Endocrinology (2004) 1.04
The TB Structural Genomics Consortium: a decade of progress. Tuberculosis (Edinb) (2011) 1.03
Lactoferrin and iron: structural and dynamic aspects of binding and release. Biometals (2004) 1.03
Roles of minor pilin subunits Spy0125 and Spy0130 in the serotype M1 Streptococcus pyogenes strain SF370. J Bacteriol (2010) 1.03
Crystal structures of the staphylococcal toxin SSL5 in complex with sialyl Lewis X reveal a conserved binding site that shares common features with viral and bacterial sialic acid binding proteins. J Mol Biol (2007) 1.02
Crystal structure of Epiphyas postvittana takeout 1 with bound ubiquinone supports a role as ligand carriers for takeout proteins in insects. J Biol Chem (2008) 1.02
Metabolic engineering of cofactor F420 production in Mycobacterium smegmatis. PLoS One (2010) 1.01
Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis. J Biol Chem (2010) 1.00
Citations in supplementary material. Acta Crystallogr D Biol Crystallogr (2010) 1.00
Structure and function of GlmU from Mycobacterium tuberculosis. Acta Crystallogr D Biol Crystallogr (2009) 0.99
Autocatalytically generated Thr-Gln ester bond cross-links stabilize the repetitive Ig-domain shaft of a bacterial cell surface adhesin. Proc Natl Acad Sci U S A (2013) 0.98
Crystal structure of Spy0129, a Streptococcus pyogenes class B sortase involved in pilus assembly. PLoS One (2011) 0.98
Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation. Mol Microbiol (2014) 0.95
The laminin-binding protein Lbp from Streptococcus pyogenes is a zinc receptor. J Bacteriol (2009) 0.95
Isopeptide bonds in bacterial pili and their characterization by X-ray crystallography and mass spectrometry. Biopolymers (2009) 0.95
Structural model for covalent adhesion of the Streptococcus pyogenes pilus through a thioester bond. J Biol Chem (2013) 0.95
Three sites and you are out: ternary synergistic allostery controls aromatic amino acid biosynthesis in Mycobacterium tuberculosis. J Mol Biol (2012) 0.92
Crystal structure and metal binding properties of the lipoprotein MtsA, responsible for iron transport in Streptococcus pyogenes. Biochemistry (2009) 0.92
Defining the potassium binding region in an apple terpene synthase. J Biol Chem (2009) 0.92
Crystal structure of a putative methyltransferase from Mycobacterium tuberculosis: misannotation of a genome clarified by protein structural analysis. J Bacteriol (2003) 0.91
Histidine phosphorylation in biological systems. Biochim Biophys Acta (2007) 0.91
High-resolution crystal structure of plant carboxylesterase AeCXE1, from Actinidia eriantha, and its complex with a high-affinity inhibitor paraoxon. Biochemistry (2007) 0.91
A structural perspective on lactoferrin function. Biochem Cell Biol (2012) 0.91
Structure of naphthoate synthase (MenB) from Mycobacterium tuberculosis in both native and product-bound forms. Acta Crystallogr D Biol Crystallogr (2005) 0.91
Structures of Mycobacterium tuberculosis folylpolyglutamate synthase complexed with ADP and AMPPCP. Acta Crystallogr D Biol Crystallogr (2008) 0.89
Structural and functional characterization of an RNase HI domain from the bifunctional protein Rv2228c from Mycobacterium tuberculosis. J Bacteriol (2010) 0.89
Inhibition studies of Mycobacterium tuberculosis salicylate synthase (MbtI). ChemMedChem (2010) 0.88
Structural and functional analysis of Rv3214 from Mycobacterium tuberculosis, a protein with conflicting functional annotations, leads to its characterization as a phosphatase. J Bacteriol (2006) 0.88
The potential impact of structural genomics on tuberculosis drug discovery. Drug Discov Today (2006) 0.87
Structure and function of human xylulokinase, an enzyme with important roles in carbohydrate metabolism. J Biol Chem (2012) 0.86
In defence of our science - validation now! Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.86
Crystallization and preliminary X-ray crystallographic analysis of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Mycobacterium tuberculosis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.85
Structures of glycinamide ribonucleotide transformylase (PurN) from Mycobacterium tuberculosis reveal a novel dimer with relevance to drug discovery. J Mol Biol (2009) 0.85
Making sense of a missense mutation: characterization of MutT2, a Nudix hydrolase from Mycobacterium tuberculosis, and the G58R mutant encoded in W-Beijing strains of M. tuberculosis. Biochemistry (2009) 0.85
The extracellular protein factor Epf from Streptococcus pyogenes is a cell surface adhesin that binds to cells through an N-terminal domain containing a carbohydrate-binding module. J Biol Chem (2012) 0.85
Structural and functional analysis of Rv0554 from Mycobacterium tuberculosis: testing a putative role in menaquinone biosynthesis. Acta Crystallogr D Biol Crystallogr (2010) 0.84
Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases. Eur J Med Chem (2007) 0.84
Structural and functional consequences of binding site mutations in transferrin: crystal structures of the Asp63Glu and Arg124Ala mutants of the N-lobe of human transferrin. Biochemistry (2003) 0.84
Crystallization and preliminary X-ray analysis of a conserved hypothetical protein PAE2754 from Pyrobaculum aerophilum and of a double Leu-->Met mutant engineered for MAD phasing. Acta Crystallogr D Biol Crystallogr (2004) 0.84
Crystallization and preliminary X-ray crystallographic analysis of MbtI, a protein essential for siderophore biosynthesis in Mycobacterium tuberculosis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2004) 0.84
Synthesis and evaluation of M. tuberculosis salicylate synthase (MbtI) inhibitors designed to probe plasticity in the active site. Org Biomol Chem (2012) 0.84
Tat-dependent translocation of an F420-binding protein of Mycobacterium tuberculosis. PLoS One (2012) 0.84
The structure and unusual protein chemistry of hypoxic response protein 1, a latency antigen and highly expressed member of the DosR regulon in Mycobacterium tuberculosis. J Mol Biol (2008) 0.83
Purification, crystallization and preliminary crystallographic analysis of mouse myo-inositol oxygenase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.82
Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis. Biochemistry (2012) 0.82
Expression, purification, crystallization and preliminary crystallographic analysis of SpaA, a major pilin from Corynebacterium diphtheriae. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.82
Crystallization and preliminary X-ray analysis of alpha-isopropylmalate synthase from Mycobacterium tuberculosis. Acta Crystallogr D Biol Crystallogr (2004) 0.82
The crystal structure of TrpD, a metabolic enzyme essential for lung colonization by Mycobacterium tuberculosis, in complex with its substrate phosphoribosylpyrophosphate. J Mol Biol (2005) 0.81
Structure of Escherichia coli UDP-N-acetylmuramoyl:L-alanine ligase (MurC). Acta Crystallogr D Biol Crystallogr (2006) 0.81
Potent inhibitors of a shikimate pathway enzyme from Mycobacterium tuberculosis: combining mechanism- and modeling-based design. J Biol Chem (2011) 0.81
Purification, crystallization and preliminary crystallographic analysis of human dihydrodipicolinate synthase-like protein (DHDPSL). Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.81
Crystallization and preliminary diffraction studies of the C-terminal domain of the DipZ homologue from Mycobacterium tuberculosis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.80
Three-dimensional structure and ligand binding properties of trichosurin, a metatherian lipocalin from the milk whey of the common brushtail possum Trichosurus vulpecula. Biochem J (2007) 0.80
Production of recombinant proteins in Mycobacterium smegmatis for structural and functional studies. Protein Sci (2014) 0.80
Structural and functional properties of staphylococcal superantigen-like protein 4. Infect Immun (2012) 0.80
Purification, crystallization and preliminary crystallographic analysis of the minor pilin FctB from Streptococcus pyogenes. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.79
Purification, crystallization and preliminary X-ray analysis of Enterococcus faecium aminoglycoside-2''-phosphotransferase-Ib [APH(2'')-Ib]. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.79
The substrate capture mechanism of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase provides a mode for inhibition. Biochemistry (2013) 0.79
An arm-swapped dimer of the Streptococcus pyogenes pilin specific assembly factor SipA. J Struct Biol (2013) 0.79
Repurposing the chemical scaffold of the anti-arthritic drug Lobenzarit to target tryptophan biosynthesis in Mycobacterium tuberculosis. Chembiochem (2014) 0.78
Cloning, expression, purification and preliminary crystallographic data for Rv3214 (EntD), a predicted cofactor-dependent phosphoglycerate mutase from Mycobacterium tuberculosis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.78
Expectation bias and information content. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.78
Cloning, expression, purification and preliminary crystallographic analysis of the RNase HI domain of the Mycobacterium tuberculosis protein Rv2228c as a maltose-binding protein fusion. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.78
Synthesis and structure-activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases. Bioorg Med Chem Lett (2008) 0.78
Removal of the C-terminal regulatory domain of α-isopropylmalate synthase disrupts functional substrate binding. Biochemistry (2012) 0.78
Structure of a domain-opened mutant (R121D) of the human lactoferrin N-lobe refined from a merohedrally twinned crystal form. Acta Crystallogr D Biol Crystallogr (2002) 0.78
Inhibition studies on Mycobacterium tuberculosis N-acetylglucosamine-1-phosphate uridyltransferase (GlmU). Org Biomol Chem (2013) 0.78
"Dilysine trigger" in transferrins probed by mutagenesis of lactoferrin: crystal structures of the R210G, R210E, and R210L mutants of human lactoferrin. Biochemistry (2002) 0.78
Use of a repetitive seeding protocol to obtain diffraction-quality crystals of a putative human D-xylulokinase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.78
Structures of two mutants that probe the role in iron release of the dilysine pair in the N-lobe of human transferrin. Acta Crystallogr D Biol Crystallogr (2007) 0.77
Crystallographic and mutational data show that the streptococcal pyrogenic exotoxin J can use a common binding surface for T-cell receptor binding and dimerization. J Biol Chem (2004) 0.77
The structure of an ancient conserved domain establishes a structural basis for stable histidine phosphorylation and identifies a new family of adenosine-specific kinases. J Biol Chem (2006) 0.77