Published in Biophys J on December 07, 2007
Calcium oscillations. Cold Spring Harb Perspect Biol (2011) 1.56
Exploring lung physiology in health and disease with lung slices. Pulm Pharmacol Ther (2011) 1.53
A multiscale, spatially distributed model of asthmatic airway hyper-responsiveness. J Theor Biol (2010) 1.18
Influence of airway wall stiffness and parenchymal tethering on the dynamics of bronchoconstriction. Am J Physiol Lung Cell Mol Physiol (2010) 1.16
Human airway contraction and formoterol-induced relaxation is determined by Ca2+ oscillations and Ca2+ sensitivity. Am J Respir Cell Mol Biol (2009) 1.11
Nitric oxide induces airway smooth muscle cell relaxation by decreasing the frequency of agonist-induced Ca2+ oscillations. J Gen Physiol (2010) 1.05
A multi-scale approach to airway hyperresponsiveness: from molecule to organ. Front Physiol (2012) 1.04
Ion channel regulation of intracellular calcium and airway smooth muscle function. Pulm Pharmacol Ther (2008) 1.01
Emergence of airway smooth muscle functions related to structural malleability. J Appl Physiol (1985) (2010) 0.96
A mathematical analysis of agonist- and KCl-induced Ca(2+) oscillations in mouse airway smooth muscle cells. Biophys J (2010) 0.95
Activation of store-operated calcium entry in airway smooth muscle cells: insight from a mathematical model. PLoS One (2013) 0.87
Modelling airway smooth muscle passive length adaptation via thick filament length distributions. J Theor Biol (2013) 0.87
Mathematical modeling of calcium signaling during sperm hyperactivation. Mol Hum Reprod (2011) 0.86
Calcium dynamics and vasomotion in arteries subject to isometric, isobaric, and isotonic conditions. Biophys J (2008) 0.84
Towards a virtual lung: multi-scale, multi-physics modelling of the pulmonary system. Philos Trans A Math Phys Eng Sci (2008) 0.84
Nonlinear compliance modulates dynamic bronchoconstriction in a multiscale airway model. Biophys J (2014) 0.83
Computational modeling of airway and pulmonary vascular structure and function: development of a "lung physiome". Crit Rev Biomed Eng (2011) 0.81
Quantifying parenchymal tethering in a finite element simulation of a human lung slice under bronchoconstriction. Respir Physiol Neurobiol (2012) 0.81
A biomechanical model for fluidization of cells under dynamic strain. Biophys J (2015) 0.81
The importance of synergy between deep inspirations and fluidization in reversing airway closure. PLoS One (2012) 0.80
Multiscale mathematical models of airway constriction and disease. Pulm Pharmacol Ther (2011) 0.80
Static and dynamic stress heterogeneity in a multiscale model of the asthmatic airway wall. J Appl Physiol (1985) (2016) 0.78
Airway and Parenchymal Strains during Bronchoconstriction in the Precision Cut Lung Slice. Front Physiol (2016) 0.78
A Ca2+- and PKC-driven regulatory network in airway smooth muscle. J Gen Physiol (2013) 0.78
Phenotype, endotype and patient-specific computational modelling for optimal treatment design in asthma. Drug Discov Today Dis Models (2014) 0.75
Muscle structure and theories of contraction. Prog Biophys Biophys Chem (1957) 32.09
Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol Rev (2003) 9.32
Calcium oscillations increase the efficiency and specificity of gene expression. Nature (1998) 9.19
Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II. J Physiol (2000) 5.24
NFAT functions as a working memory of Ca2+ signals in decoding Ca2+ oscillation. EMBO J (2003) 2.24
G protein-mediated inhibition of myosin light-chain phosphatase in vascular smooth muscle. Proc Natl Acad Sci U S A (1991) 2.21
The frequency of calcium oscillations induced by 5-HT, ACH, and KCl determine the contraction of smooth muscle cells of intrapulmonary bronchioles. J Gen Physiol (2005) 2.15
Cross-bridge phosphorylation and regulation of latch state in smooth muscle. Am J Physiol (1988) 2.10
Acetylcholine-induced calcium signaling and contraction of airway smooth muscle cells in lung slices. J Gen Physiol (2002) 1.82
Ca2+, crossbridge phosphorylation, and contraction. Annu Rev Physiol (1989) 1.78
Cyclic GMP causes Ca2+ desensitization in vascular smooth muscle by activating the myosin light chain phosphatase. J Biol Chem (1997) 1.62
Modulation of the Ca2+ sensitivity of airway smooth muscle cells in murine lung slices. Am J Physiol Lung Cell Mol Physiol (2006) 1.61
Perturbed equilibria of myosin binding in airway smooth muscle: bond-length distributions, mechanics, and ATP metabolism. Biophys J (2000) 1.52
The contraction of smooth muscle cells of intrapulmonary arterioles is determined by the frequency of Ca2+ oscillations induced by 5-HT and KCl. J Gen Physiol (2005) 1.42
Regulation of shortening velocity by cross-bridge phosphorylation in smooth muscle. Am J Physiol (1988) 1.40
Agonist-induced changes in the phosphorylation of the myosin- binding subunit of myosin light chain phosphatase and CPI17, two regulatory factors of myosin light chain phosphatase, in smooth muscle. Biochem J (2003) 1.38
'Sarcomeres' of smooth muscle: functional characteristics and ultrastructural evidence. J Cell Sci (2005) 1.35
Quantitative measurements of Ca(2+)/calmodulin binding and activation of myosin light chain kinase in cells. FEBS Lett (2004) 1.27
Parenchymal tethering, airway wall stiffness, and the dynamics of bronchoconstriction. J Appl Physiol (1985) (2007) 1.27
Acceleration of myosin light chain dephosphorylation and relaxation of smooth muscle by telokin. Synergism with cyclic nucleotide-activated kinase. J Biol Chem (1998) 1.26
Agonist- and depolarization-induced signals for myosin light chain phosphorylation and force generation of cultured vascular smooth muscle cells. J Cell Sci (2006) 1.13
What is special about smooth muscle? The significance of covalent crossbridge regulation. FASEB J (1994) 1.13
Contractility and Ca2+ signaling of smooth muscle cells in different generations of mouse airways. Am J Respir Cell Mol Biol (2006) 1.08
Mass determination of native smooth muscle myosin filaments by scanning transmission electron microscopy. J Mol Biol (2002) 0.96
Decoding of calcium oscillations by phosphorylation cycles: analytic results. Biophys J (2007) 0.96
Mathematical modeling of the myosin light chain kinase activation. J Chem Inf Model (2005) 0.87
A signal transduction pathway model prototype II: Application to Ca2+-calmodulin signaling and myosin light chain phosphorylation. Biophys J (2004) 0.84
Theoretical and experimental investigation of calcium-contraction coupling in airway smooth muscle. Cell Biochem Biophys (2006) 0.79
Angiosperm phylogeny: 17 genes, 640 taxa. Am J Bot (2011) 3.54
A phylogeny of legumes (Leguminosae) based on analysis of the plastid matK gene resolves many well-supported subclades within the family. Am J Bot (2004) 3.32
Testing for different rates of continuous trait evolution using likelihood. Evolution (2006) 2.78
Prospects for building the tree of life from large sequence databases. Science (2004) 2.56
The frequency of calcium oscillations induced by 5-HT, ACH, and KCl determine the contraction of smooth muscle cells of intrapulmonary bronchioles. J Gen Physiol (2005) 2.15
Mutations in Hydin impair ciliary motility in mice. J Cell Biol (2008) 2.06
Angiosperm divergence times: the effect of genes, codon positions, and time constraints. Evolution (2005) 2.04
What do aquaporin knockout studies tell us about fluid transport in epithelia? J Membr Biol (2013) 2.03
Phylogenetic supermatrix analysis of GenBank sequences from 2228 papilionoid legumes. Syst Biol (2006) 2.00
Assessing the quality of molecular divergence time estimates by fossil calibrations and fossil-based model selection. Philos Trans R Soc Lond B Biol Sci (2004) 1.96
Acetylcholine-induced calcium signaling and contraction of airway smooth muscle cells in lung slices. J Gen Physiol (2002) 1.82
Intermolecular failure of L-type Ca2+ channel and ryanodine receptor signaling in hypertrophy. PLoS Biol (2007) 1.70
Genomic regions linked to alcohol consumption in the Framingham Heart Study. BMC Genet (2003) 1.63
Modulation of the Ca2+ sensitivity of airway smooth muscle cells in murine lung slices. Am J Physiol Lung Cell Mol Physiol (2006) 1.61
Evolution of genome size in pines (Pinus) and its life-history correlates: supertree analyses. Evolution (2004) 1.59
Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanism. Dev Cell (2010) 1.49
Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair. J Cell Biol (2010) 1.49
Coagulation under flow: the influence of flow-mediated transport on the initiation and inhibition of coagulation. Pathophysiol Haemost Thromb (2005) 1.46
The ciliary rootlet maintains long-term stability of sensory cilia. Mol Cell Biol (2005) 1.43
The contraction of smooth muscle cells of intrapulmonary arterioles is determined by the frequency of Ca2+ oscillations induced by 5-HT and KCl. J Gen Physiol (2005) 1.42
Regulation of airway smooth muscle cell contractility by Ca2+ signaling and sensitivity. Proc Am Thorac Soc (2008) 1.41
TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells. Proc Natl Acad Sci U S A (2008) 1.36
Oscillations in ciliary beat frequency and intracellular calcium concentration in rabbit tracheal epithelial cells induced by ATP. J Physiol (2003) 1.34
Intercellular Ca(2+) waves: mechanisms and function. Physiol Rev (2012) 1.32
Nuclear calcium/calmodulin-dependent protein kinase IIdelta preferentially transmits signals to histone deacetylase 4 in cardiac cells. J Biol Chem (2006) 1.32
Airway smooth muscle relaxation results from a reduction in the frequency of Ca2+ oscillations induced by a cAMP-mediated inhibition of the IP3 receptor. Respir Res (2006) 1.30
The small-world dynamics of tree networks and data mining in phyloinformatics. Bioinformatics (2003) 1.29
Phosphorylation-dependent degradation of p300 by doxorubicin-activated p38 mitogen-activated protein kinase in cardiac cells. Mol Cell Biol (2005) 1.27
KRAB zinc finger protein ZNF382 is a proapoptotic tumor suppressor that represses multiple oncogenes and is commonly silenced in multiple carcinomas. Cancer Res (2010) 1.26
MCMC estimation of Markov models for ion channels. Biophys J (2011) 1.25
Spontaneous resolution of silver double helicates consisting of achiral ligands with several aromatic rings. Chem Commun (Camb) (2006) 1.23
Bmp signaling regulates a dose-dependent transcriptional program to control facial skeletal development. Development (2012) 1.22
Performance of flip supertree construction with a heuristic algorithm. Syst Biol (2004) 1.20
Supertree bootstrapping methods for assessing phylogenetic variation among genes in genome-scale data sets. Syst Biol (2006) 1.19
Ciliary beat frequency is maintained at a maximal rate in the small airways of mouse lung slices. Am J Respir Cell Mol Biol (2006) 1.18
A multiscale, spatially distributed model of asthmatic airway hyper-responsiveness. J Theor Biol (2010) 1.18
Nematode small subunit phylogeny correlates with alignment parameters. Syst Biol (2006) 1.17
Influence of airway wall stiffness and parenchymal tethering on the dynamics of bronchoconstriction. Am J Physiol Lung Cell Mol Physiol (2010) 1.16
Airway contractility and smooth muscle Ca(2+) signaling in lung slices from different mouse strains. J Appl Physiol (1985) (2003) 1.16
MCMC can detect nonidentifiable models. Biophys J (2012) 1.15
The contribution of Ca2+ signaling and Ca2+ sensitivity to the regulation of airway smooth muscle contraction is different in rats and mice. Am J Physiol Lung Cell Mol Physiol (2009) 1.15
Relationships among seed plants inferred from highly conserved genes: sorting conflicting phylogenetic signals among ancient lineages. Am J Bot (2002) 1.13
Family history of gallstones and the risk of biliary tract cancer and gallstones: a population-based study in Shanghai, China. Int J Cancer (2007) 1.13
Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor. Proc Natl Acad Sci U S A (2011) 1.12
Cytosolic Ca(2+) and Ca(2+)-activated Cl(-) current dynamics: insights from two functionally distinct mouse exocrine cells. J Physiol (2002) 1.11
Human airway contraction and formoterol-induced relaxation is determined by Ca2+ oscillations and Ca2+ sensitivity. Am J Respir Cell Mol Biol (2009) 1.11
ATP stimulates Ca2+ oscillations and contraction in airway smooth muscle cells of mouse lung slices. Am J Physiol Lung Cell Mol Physiol (2002) 1.09
Covarion structure in plastid genome evolution: a new statistical test. Mol Biol Evol (2004) 1.09
Surface decoration by Spirulina polysaccharide enhances the cellular uptake and anticancer efficacy of selenium nanoparticles. Int J Nanomedicine (2012) 1.08
Contractility and Ca2+ signaling of smooth muscle cells in different generations of mouse airways. Am J Respir Cell Mol Biol (2006) 1.08
A kinetic model for type I and II IP3R accounting for mode changes. Biophys J (2012) 1.08
Genomewide linkage screen for Waldenstrom macroglobulinemia susceptibility loci in high-risk families. Am J Hum Genet (2006) 1.08
Pitx2, an atrial fibrillation predisposition gene, directly regulates ion transport and intercalated disc genes. Circ Cardiovasc Genet (2014) 1.07
Mir-24 regulates junctophilin-2 expression in cardiomyocytes. Circ Res (2012) 1.07
In vivo suppression of microRNA-24 prevents the transition toward decompensated hypertrophy in aortic-constricted mice. Circ Res (2013) 1.07
Identification of small-molecule inhibitors of ricin and shiga toxin using a cell-based high-throughput screen. Toxicon (2010) 1.06
M1 muscarinic receptors inhibit L-type Ca2+ current and M-current by divergent signal transduction cascades. J Neurosci (2006) 1.06
Nitric oxide induces airway smooth muscle cell relaxation by decreasing the frequency of agonist-induced Ca2+ oscillations. J Gen Physiol (2010) 1.05
Aa TFL1 confers an age-dependent response to vernalization in perennial Arabis alpina. Plant Cell (2011) 1.05
A multi-scale approach to airway hyperresponsiveness: from molecule to organ. Front Physiol (2012) 1.04
Two slow calcium-activated afterhyperpolarization currents control burst firing dynamics in gonadotropin-releasing hormone neurons. J Neurosci (2010) 1.04
Markov chain Monte Carlo fitting of single-channel data from inositol trisphosphate receptors. J Theor Biol (2008) 1.03
A mathematical model of fluid secretion from a parotid acinar cell. J Theor Biol (2007) 1.01
Ion channel regulation of intracellular calcium and airway smooth muscle function. Pulm Pharmacol Ther (2008) 1.01
Selenium nanoparticles fabricated in Undaria pinnatifida polysaccharide solutions induce mitochondria-mediated apoptosis in A375 human melanoma cells. Colloids Surf B Biointerfaces (2008) 1.00
In vivo regulation of Grp78/BiP transcription in the embryonic heart: role of the endoplasmic reticulum stress response element and GATA-4. J Biol Chem (2006) 1.00
Entanglement of individual coordination polymers having helicates as building intermediates. Dalton Trans (2007) 1.00
A dynamic model of saliva secretion. J Theor Biol (2010) 0.99
The contribution of inositol 1,4,5-trisphosphate and ryanodine receptors to agonist-induced Ca(2+) signaling of airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol (2009) 0.99
MicroRNA-17-92, a direct Ap-2α transcriptional target, modulates T-box factor activity in orofacial clefting. PLoS Genet (2013) 0.98
A continuous-binding cross-linker model for passive airway smooth muscle. Biophys J (2010) 0.98
Effects of formoterol on contraction and Ca2+ signaling of mouse airway smooth muscle cells. Am J Respir Cell Mol Biol (2009) 0.98
Critical role of nuclear calcium/calmodulin-dependent protein kinase IIdeltaB in cardiomyocyte survival in cardiomyopathy. J Biol Chem (2009) 0.98
Relaxed molecular clocks, the bias-variance trade-off, and the quality of phylogenetic inference. Syst Biol (2009) 0.97
Large-scale patterns of diversification in the widespread legume genus Senna and the evolutionary role of extrafloral nectaries. Evolution (2010) 0.97
Could an increase in airway smooth muscle shortening velocity cause airway hyperresponsiveness? Am J Physiol Lung Cell Mol Physiol (2010) 0.97
Locating evolutionary precursors on a phylogenetic tree. Evolution (2012) 0.97
Bitter tasting compounds dilate airways by inhibiting airway smooth muscle calcium oscillations and calcium sensitivity. Br J Pharmacol (2014) 0.97
Spindle pole body-anchored Kar3 drives the nucleus along microtubules from another nucleus in preparation for nuclear fusion during yeast karyogamy. Genes Dev (2013) 0.96
Integration of left-right Pitx2 transcription and Wnt signaling drives asymmetric gut morphogenesis via Daam2. Dev Cell (2013) 0.96
Endothelin-induced contraction of bronchiole and pulmonary arteriole smooth muscle cells is regulated by intracellular Ca2+ oscillations and Ca2+ sensitization. Am J Physiol Lung Cell Mol Physiol (2007) 0.96
Reduction of Na/K-ATPase potentiates marinobufagenin-induced cardiac dysfunction and myocyte apoptosis. J Biol Chem (2012) 0.95
A mathematical analysis of agonist- and KCl-induced Ca(2+) oscillations in mouse airway smooth muscle cells. Biophys J (2010) 0.95
Development and validation of small-diameter vascular tissue from a decellularized scaffold coated with heparin and vascular endothelial growth factor. Artif Organs (2009) 0.95
A buffering SERCA pump in models of calcium dynamics. Biophys J (2006) 0.95
Effects of albuterol isomers on the contraction and Ca2+ signaling of small airways in mouse lung slices. Am J Respir Cell Mol Biol (2007) 0.95
Cell signaling associated with Na(+)/K(+)-ATPase: activation of phosphatidylinositide 3-kinase IA/Akt by ouabain is independent of Src. Biochemistry (2013) 0.94
The significance of few versus many in the tree of life. Science (2004) 0.93
A stochastic model of calcium puffs based on single-channel data. Biophys J (2013) 0.93
A kinetic model of the inositol trisphosphate receptor based on single-channel data. Biophys J (2009) 0.93
CD28 and ITK signals regulate autoreactive T cell trafficking. Nat Med (2013) 0.93
Targeting antigen to MHC class II molecules promotes efficient cross-presentation and enhances immunotherapy. J Immunol (2009) 0.93
Synergistic and sequential effects of BMP-2, bFGF and VEGF on osteogenic differentiation of rat osteoblasts. J Bone Miner Metab (2013) 0.92