Published in Am J Physiol Heart Circ Physiol on December 07, 2007
Glucocorticoid induction of occludin expression and endothelial barrier requires transcription factor p54 NONO. Invest Ophthalmol Vis Sci (2013) 1.46
The atherosusceptible endothelium: endothelial phenotypes in complex haemodynamic shear stress regions in vivo. Cardiovasc Res (2013) 1.30
Developmental timing of CCM2 loss influences cerebral cavernous malformations in mice. J Exp Med (2011) 1.25
Wnt signaling mediates pathological vascular growth in proliferative retinopathy. Circulation (2011) 1.18
Glial influence on the blood brain barrier. Glia (2013) 1.12
ETS-related gene (ERG) controls endothelial cell permeability via transcriptional regulation of the claudin 5 (CLDN5) gene. J Biol Chem (2012) 1.11
Claudin and occludin expression and function in the seminiferous epithelium. Philos Trans R Soc Lond B Biol Sci (2010) 1.01
The blood-brain barrier. Cold Spring Harb Perspect Biol (2015) 1.00
Tumor lymphangiogenesis as a potential therapeutic target. J Oncol (2012) 0.97
Ligand binding and signaling of dendritic cell immunoreceptor (DCIR) is modulated by the glycosylation of the carbohydrate recognition domain. PLoS One (2013) 0.85
Anthrax lethal toxin downregulates claudin-5 expression in human endothelial tight junctions. PLoS One (2013) 0.84
The oncogenic MicroRNA Hsa-miR-155-5p targets the transcription factor ELK3 and links it to the hypoxia response. PLoS One (2014) 0.83
Early growth response protein 1 acts as an activator of SOX18 promoter. Exp Mol Med (2010) 0.82
The transcription factor SOX18 regulates the expression of matrix metalloproteinase 7 and guidance molecules in human endothelial cells. PLoS One (2012) 0.81
Interleukin-4 induces up-regulation of endothelial cell claudin-5 through activation of FoxO1: role in protection from complement-mediated injury. J Biol Chem (2013) 0.80
Opening tight junctions may be key to opening the blood-prostate barrier. Med Sci Monit (2014) 0.79
Rho kinase: A new target for treatment of cerebral ischemia/reperfusion injury. Neural Regen Res (2013) 0.79
Sox18 preserves the pulmonary endothelial barrier under conditions of increased shear stress. J Cell Physiol (2014) 0.75
Endothelial Cell Signaling and Ventilator-Induced Lung Injury (VILI): Molecular Mechanisms, Genomic Analyses & Therapeutic Targets. Am J Physiol Lung Cell Mol Physiol (2016) 0.75
Expression of the ALS-causing variant hSOD1(G93A) leads to an impaired integrity and altered regulation of claudin-5 expression in an in vitro blood-spinal cord barrier model. J Cereb Blood Flow Metab (2015) 0.75
Expression of Nitric Oxide-Transporting Aquaporin-1 Is Controlled by KLF2 and Marks Non-Activated Endothelium In Vivo. PLoS One (2015) 0.75
Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Nat Cell Biol (2012) 5.12
MicroRNA-34a regulates cardiac ageing and function. Nature (2013) 4.03
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. Science (2011) 3.52
Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Krüppel-like factor (KLF2). Blood (2002) 3.38
KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium. Blood (2006) 2.41
The range of adaptation by collateral vessels after femoral artery occlusion. Circ Res (2006) 2.31
The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue. Genomics (2002) 2.20
MicroRNA-29 in aortic dilation: implications for aneurysm formation. Circ Res (2011) 2.01
Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes. Am J Pathol (2005) 1.98
Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization. Cardiovasc Res (2006) 1.80
Macrophages and neurodegeneration. Brain Res Brain Res Rev (2005) 1.64
Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling. FASEB J (2007) 1.63
Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: identification of heat shock response as the major pathway activated by nitro-oleic acid. J Biol Chem (2009) 1.58
PPARγ activation but not PPARγ haplodeficiency affects proangiogenic potential of endothelial cells and bone marrow-derived progenitors. Cardiovasc Diabetol (2014) 1.48
Puromycin-purified rat brain microvascular endothelial cell cultures exhibit improved barrier properties in response to glucocorticoid induction. J Neurochem (2006) 1.43
Effect of additional treatment with EXenatide in patients with an Acute Myocardial Infarction: the EXAMI study. Int J Cardiol (2012) 1.41
Radical changes in multiple sclerosis pathogenesis. Biochim Biophys Acta (2010) 1.40
Pluriformity of inflammation in multiple sclerosis shown by ultra-small iron oxide particle enhancement. Brain (2008) 1.38
Diapedesis of monocytes is associated with MMP-mediated occludin disappearance in brain endothelial cells. FASEB J (2006) 1.34
Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration? Mitochondrion (2010) 1.34
Flavonoids influence monocytic GTPase activity and are protective in experimental allergic encephalitis. J Exp Med (2004) 1.34
Primary cilia sensitize endothelial cells for fluid shear stress. Dev Dyn (2008) 1.33
The blood-brain barrier and its role in immune privilege in the central nervous system. J Neuropathol Exp Neurol (2003) 1.32
Interferon-beta signaling is enhanced in patients with insufficient coronary collateral artery development and inhibits arteriogenesis in mice. Circ Res (2008) 1.32
KLF2 primes the antioxidant transcription factor Nrf2 for activation in endothelial cells. Arterioscler Thromb Vasc Biol (2008) 1.31
Lipoic acid affects cellular migration into the central nervous system and stabilizes blood-brain barrier integrity. J Immunol (2006) 1.30
Amyloid Beta induces oxidative stress-mediated blood-brain barrier changes in capillary amyloid angiopathy. Antioxid Redox Signal (2011) 1.29
Neurotrophin p75 receptor (p75NTR) promotes endothelial cell apoptosis and inhibits angiogenesis: implications for diabetes-induced impaired neovascularization in ischemic limb muscles. Circ Res (2008) 1.29
Comparison of SPIO and USPIO for in vitro labeling of human monocytes: MR detection and cell function. Radiology (2007) 1.28
Prolonged shear stress and KLF2 suppress constitutive proinflammatory transcription through inhibition of ATF2. Blood (2007) 1.27
Rosuvastatin reduces atherosclerosis development beyond and independent of its plasma cholesterol-lowering effect in APOE*3-Leiden transgenic mice: evidence for antiinflammatory effects of rosuvastatin. Circulation (2003) 1.27
Fingolimod attenuates ceramide-induced blood-brain barrier dysfunction in multiple sclerosis by targeting reactive astrocytes. Acta Neuropathol (2012) 1.22
Interferon-beta prevents cytokine-induced neutrophil infiltration and attenuates blood-brain barrier disruption. J Cereb Blood Flow Metab (2003) 1.21
The blood-brain barrier in cortical multiple sclerosis lesions. J Neuropathol Exp Neurol (2007) 1.20
Retinoic acid induces blood-brain barrier development. J Neurosci (2013) 1.17
RhoA activation promotes transendothelial migration of monocytes via ROCK. J Leukoc Biol (2003) 1.16
Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions. Glia (2010) 1.15
Inhibition of mammalian target of rapamycin reduces epileptogenesis and blood-brain barrier leakage but not microglia activation. Epilepsia (2012) 1.15
Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis. Neurobiol Dis (2005) 1.14
Matrix metalloproteinase-12 is expressed in phagocytotic macrophages in active multiple sclerosis lesions. J Neuroimmunol (2003) 1.14
Magnetic resonance imaging-defined areas of microvascular obstruction after acute myocardial infarction represent microvascular destruction and haemorrhage. Eur Heart J (2013) 1.11
Galectin-2 expression is dependent on the rs7291467 polymorphism and acts as an inhibitor of arteriogenesis. Eur Heart J (2011) 1.10
Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation. J Neuroinflammation (2012) 1.09
KLF2-induced actin shear fibers control both alignment to flow and JNK signaling in vascular endothelium. Blood (2009) 1.08
MRI of monocyte infiltration in an animal model of neuroinflammation using SPIO-labeled monocytes or free USPIO. J Cereb Blood Flow Metab (2007) 1.07
Ultrasound and microbubble-induced intra- and intercellular bioeffects in primary endothelial cells. Ultrasound Med Biol (2009) 1.07
MicroRNAs regulate human brain endothelial cell-barrier function in inflammation: implications for multiple sclerosis. J Neurosci (2013) 1.07
Comparative proteomics of human endothelial cell caveolae and rafts using two-dimensional gel electrophoresis and mass spectrometry. Electrophoresis (2004) 1.06
Kruppel-like factor 2 improves neovascularization capacity of aged proangiogenic cells. Eur Heart J (2010) 1.04
Therapeutic potential and biological role of endogenous antioxidant enzymes in multiple sclerosis pathology. Brain Res Rev (2007) 1.04
Actin-binding rho activating protein (Abra) is essential for fluid shear stress-induced arteriogenesis. Arterioscler Thromb Vasc Biol (2009) 1.03
Distinctive expression of chemokines and transforming growth factor-beta signaling in human arterial endothelium during atherosclerosis. Am J Pathol (2007) 1.03
Basement membrane proteins in multiple sclerosis-associated inflammatory cuffs: potential role in influx and transport of leukocytes. J Neuropathol Exp Neurol (2005) 1.03
Extensive extracellular matrix depositions in active multiple sclerosis lesions. Neurobiol Dis (2006) 1.02
KLF2 suppresses TGF-beta signaling in endothelium through induction of Smad7 and inhibition of AP-1. Arterioscler Thromb Vasc Biol (2006) 1.01
Tissue-type plasminogen activator is a multiligand cross-beta structure receptor. Curr Biol (2002) 1.01
Nrf2 and DJ1 are consistently upregulated in inflammatory multiple sclerosis lesions. Free Radic Biol Med (2010) 1.00
Functions of lipid raft membrane microdomains at the blood-brain barrier. J Mol Med (Berl) (2009) 0.99
Characterization of the differential response of endothelial cells exposed to normal and elevated laminar shear stress. J Cell Physiol (2011) 0.99
Soluble helminth products suppress clinical signs in murine experimental autoimmune encephalomyelitis and differentially modulate human dendritic cell activation. Mol Immunol (2012) 0.98
Dead or alive: gene expression profiles of advanced atherosclerotic plaques from autopsy and surgery. Physiol Genomics (2007) 0.98
Suppression of inflammatory signaling in monocytes from patients with coronary artery disease. J Mol Cell Cardiol (2008) 0.98
Spatial segregation of transport and signalling functions between human endothelial caveolae and lipid raft proteomes. Biochem J (2006) 0.98
Heme oxygenase-1 is required for angiogenic function of bone marrow-derived progenitor cells: role in therapeutic revascularization. Antioxid Redox Signal (2014) 0.98
Macrophages migrate in an activation-dependent manner to chemokines involved in neuroinflammation. J Neuroinflammation (2014) 0.97
Leukemia inhibitory factor modulates production of inflammatory mediators and myelin phagocytosis by macrophages. J Neuroimmunol (2008) 0.97
Mycophenolate mofetil attenuates plaque inflammation in patients with symptomatic carotid artery stenosis. Atherosclerosis (2010) 0.96
Tissue-type plasminogen activator is a regulator of monocyte diapedesis through the brain endothelial barrier. J Immunol (2008) 0.95
Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma. FASEB J (2012) 0.95
Tumor infiltrating macrophages reduce development of peritoneal colorectal carcinoma metastases. Cancer Lett (2008) 0.95
Reduced expression of PGC-1α partly underlies mitochondrial changes and correlates with neuronal loss in multiple sclerosis cortex. Acta Neuropathol (2012) 0.95
Recombinant endostatin forms amyloid fibrils that bind and are cytotoxic to murine neuroblastoma cells in vitro. FEBS Lett (2003) 0.94
Limited contribution of claudin-5-dependent tight junction strands to endothelial barrier function. Eur J Cell Biol (2006) 0.94
Flavonoids inhibit myelin phagocytosis by macrophages; a structure-activity relationship study. Biochem Pharmacol (2003) 0.93
Antioxidative defense mechanisms controlled by Nrf2: state-of-the-art and clinical perspectives in neurodegenerative diseases. Arch Toxicol (2014) 0.92
The extracellular matrix in multiple sclerosis pathology. J Neurochem (2007) 0.91