Published in Invest Ophthalmol Vis Sci on June 12, 2013
Diabetic macular edema: new concepts in patho-physiology and treatment. Cell Biosci (2014) 0.95
Tight Junctions and the Tumor Microenvironment. Curr Pathobiol Rep (2016) 0.78
Identification of genes and transcription factors associated with glucocorticoid response in lens epithelial cells. Mol Med Rep (2015) 0.76
A novel mechanism for glucocorticoid-induced tightening of endothelial barriers. Invest Ophthalmol Vis Sci (2013) 0.75
Minireview: Steroid/nuclear receptor-regulated dynamics of occluding and anchoring junctions. Mol Endocrinol (2014) 0.75
Regulation of PCGEM1 by p54/nrb in prostate cancer. Sci Rep (2016) 0.75
Glucocorticoids in the management of peritumoral brain edema: a review of molecular mechanisms. Childs Nerv Syst (2016) 0.75
Astrocyte-endothelial interactions at the blood-brain barrier. Nat Rev Neurosci (2006) 12.23
Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice. J Cell Biol (2003) 5.74
The fate of dsRNA in the nucleus: a p54(nrb)-containing complex mediates the nuclear retention of promiscuously A-to-I edited RNAs. Cell (2001) 4.72
Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature. Science (2008) 3.86
Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells. J Cell Biol (1999) 3.78
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. Science (2011) 3.52
Molecular architecture of tight junctions. Annu Rev Physiol (1998) 3.40
Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5. Nat Cell Biol (2008) 3.15
Electrical method for detection of endothelial cell shape change in real time: assessment of endothelial barrier function. Proc Natl Acad Sci U S A (1992) 3.00
Occludin as a possible determinant of tight junction permeability in endothelial cells. J Cell Sci (1997) 2.97
Tight junction pore and leak pathways: a dynamic duo. Annu Rev Physiol (2011) 2.67
A 2-year prospective randomized controlled trial of intravitreal bevacizumab or laser therapy (BOLT) in the management of diabetic macular edema: 24-month data: report 3. Arch Ophthalmol (2012) 2.42
Intraocular pressure after intravitreal injection of triamcinolone acetonide. Br J Ophthalmol (2003) 2.39
Sustained delivery fluocinolone acetonide vitreous inserts provide benefit for at least 3 years in patients with diabetic macular edema. Ophthalmology (2012) 2.32
Treatment with intravitreal steroid reduces blood-retinal barrier breakdown due to retinal photocoagulation. Arch Ophthalmol (1992) 2.07
p54(nrb) associates with the 5' splice site within large transcription/splicing complexes. EMBO J (2004) 2.06
Tight junctions: molecular architecture and function. Int Rev Cytol (2006) 2.01
Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeability. J Biol Chem (2009) 1.81
The management of brain edema in brain tumors. Curr Opin Oncol (2004) 1.67
Mechanism of dexamethasone suppression of brain tumor-associated vascular permeability in rats. Involvement of the glucocorticoid receptor and vascular permeability factor. J Clin Invest (1996) 1.63
Expression from the human occludin promoter is affected by tumor necrosis factor alpha and interferon gamma. J Cell Sci (2000) 1.60
TNF-α signals through PKCζ/NF-κB to alter the tight junction complex and increase retinal endothelial cell permeability. Diabetes (2010) 1.60
Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function. J Cell Biol (2011) 1.58
Hydrocortisone decreases retinal endothelial cell water and solute flux coincident with increased content and decreased phosphorylation of occludin. J Neurochem (2002) 1.54
Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for diabetic macular oedema. Cochrane Database Syst Rev (2012) 1.52
Mapping the blood vessels with paracellular permeability in the retinas of diabetic rats. Invest Ophthalmol Vis Sci (2003) 1.45
A coactivator trap identifies NONO (p54nrb) as a component of the cAMP-signaling pathway. Proc Natl Acad Sci U S A (2007) 1.34
The Wisconsin epidemiological study of diabetic retinopathy: a review. Diabetes Metab Rev (1989) 1.33
The critical component to establish in vitro BBB model: Pericyte. Brain Res Brain Res Rev (2005) 1.32
Occludin as direct target for glucocorticoid-induced improvement of blood-brain barrier properties in a murine in vitro system. J Physiol (2005) 1.30
p54nrb acts as a transcriptional coactivator for activation function 1 of the human androgen receptor. Biochem Biophys Res Commun (2003) 1.29
Changes in cytoskeletal and tight junctional proteins correlate with decreased permeability induced by dexamethasone in cultured rat brain endothelial cells. Neurosci Lett (2003) 1.26
Paraspeckle protein p54nrb links Sox9-mediated transcription with RNA processing during chondrogenesis in mice. J Clin Invest (2008) 1.26
The blood-retinal barrier: structure and functional significance. Methods Mol Biol (2011) 1.20
p54nrb is a transcriptional corepressor of the progesterone receptor that modulates transcription of the labor-associated gene, connexin 43 (Gja1). Mol Endocrinol (2009) 1.18
Protein kinase cβ phosphorylates occludin regulating tight junction trafficking in vascular endothelial growth factor-induced permeability in vivo. Diabetes (2012) 1.13
Intravitreal dexamethasone implant in patients with persistent diabetic macular edema. Ophthalmologica (2012) 1.13
ETS-related gene (ERG) controls endothelial cell permeability via transcriptional regulation of the claudin 5 (CLDN5) gene. J Biol Chem (2012) 1.11
Five-year results of a randomized trial with open-label extension of triamcinolone acetonide for refractory diabetic macular edema. Ophthalmology (2009) 1.11
Glucocorticoid-induced formation of tight junctions in mouse mammary epithelial cells in vitro. Proc Natl Acad Sci U S A (1992) 1.08
SOX-18 controls endothelial-specific claudin-5 gene expression and barrier function. Am J Physiol Heart Circ Physiol (2007) 1.05
Altered expression of genes related to blood-retina barrier disruption in streptozotocin-induced diabetes. Exp Eye Res (2009) 1.03
Cloning and characterization of the murine claudin-5 promoter. Mol Cell Endocrinol (2008) 1.01
TNF-alpha induced NFκB signaling and p65 (RelA) overexpression repress Cldn5 promoter in mouse brain endothelial cells. Cytokine (2011) 1.01
Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1). J Biol Chem (2012) 0.99
Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-element. Exp Eye Res (2008) 0.98
Occludin independently regulates permeability under hydrostatic pressure and cell division in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (2008) 0.97
Corticosteroid use for diabetic macular edema: old fad or new trend? Curr Diab Rep (2012) 0.97
Maternal glucocorticoid exposure alters tight junction protein expression in the brain of fetal sheep. Am J Physiol Heart Circ Physiol (2009) 0.96
Treatment of macular edema due to retinal vein occlusions. Clin Ophthalmol (2011) 0.95
Isolation and characterization of retinal endothelial cells. Methods Mol Med (2003) 0.95
The gold standard of noninfectious uveitis: corticosteroids. Dev Ophthalmol (2012) 0.88
Transcriptional control of occludin expression in vascular endothelia: regulation by Sp3 and YY1. Biochim Biophys Acta (2009) 0.88
Hydrocortisone enhances the function of the blood-nerve barrier through the up-regulation of claudin-5. Neurochem Res (2011) 0.88
Transcriptional activity of the murine retinol-binding protein gene is regulated by a multiprotein complex containing HMGA1, p54 nrb/NonO, protein-associated splicing factor (PSF) and steroidogenic factor 1 (SF1)/liver receptor homologue 1 (LRH-1). Int J Biochem Cell Biol (2009) 0.87
Glucocorticoids regulate the human occludin gene through a single imperfect palindromic glucocorticoid response element. Mol Cell Endocrinol (2008) 0.86
VEGF increases paracellular transport without altering the solvent-drag reflection coefficient. Microvasc Res (2004) 0.84
The use of intravitreal etanercept in diabetic macular oedema. Semin Ophthalmol (2007) 0.84
A three-pore model describes transport properties of bovine retinal endothelial cells in normal and elevated glucose. Invest Ophthalmol Vis Sci (2011) 0.78
Diabetic retinopathy: more than meets the eye. Surv Ophthalmol (2002) 2.95
The Ins2Akita mouse as a model of early retinal complications in diabetes. Invest Ophthalmol Vis Sci (2005) 2.83
Regulation of tight junctions and loss of barrier function in pathophysiology. Int J Biochem Cell Biol (2004) 2.54
A diet-induced mouse model for glutaric aciduria type I. Brain (2006) 2.31
VEGF activation of protein kinase C stimulates occludin phosphorylation and contributes to endothelial permeability. Invest Ophthalmol Vis Sci (2006) 1.86
Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeability. J Biol Chem (2009) 1.81
TNF-α signals through PKCζ/NF-κB to alter the tight junction complex and increase retinal endothelial cell permeability. Diabetes (2010) 1.60
Diabetes reduces basal retinal insulin receptor signaling: reversal with systemic and local insulin. Diabetes (2006) 1.58
Mapping the blood vessels with paracellular permeability in the retinas of diabetic rats. Invest Ophthalmol Vis Sci (2003) 1.45
Vascular permeability in ocular disease and the role of tight junctions. Angiogenesis (2007) 1.44
Characterization of insulin signaling in rat retina in vivo and ex vivo. Am J Physiol Endocrinol Metab (2003) 1.29
Whole genome assessment of the retinal response to diabetes reveals a progressive neurovascular inflammatory response. BMC Med Genomics (2008) 1.23
The blood-retinal barrier: structure and functional significance. Methods Mol Biol (2011) 1.20
Platelet-derived growth factor mediates tight junction redistribution and increases permeability in MDCK cells. J Cell Physiol (2002) 1.16
Glucocorticoid regulation of endothelial cell tight junction gene expression: novel treatments for diabetic retinopathy. Curr Eye Res (2005) 1.15
Protein kinase cβ phosphorylates occludin regulating tight junction trafficking in vascular endothelial growth factor-induced permeability in vivo. Diabetes (2012) 1.13
Alterations to the blood-retinal barrier in diabetes: cytokines and reactive oxygen species. Antioxid Redox Signal (2011) 1.11
Minocycline prevents retinal inflammation and vascular permeability following ischemia-reperfusion injury. J Neuroinflammation (2013) 1.08
Ocular Anti-VEGF therapy for diabetic retinopathy: the role of VEGF in the pathogenesis of diabetic retinopathy. Diabetes Care (2014) 1.07
Evaluation of the role of P-glycoprotein in the uptake of paroxetine, clozapine, phenytoin and carbamazapine by bovine retinal endothelial cells. Neuropharmacology (2005) 1.07
Identification and analysis of occludin phosphosites: a combined mass spectrometry and bioinformatics approach. J Proteome Res (2009) 1.05
Efficacy of interleukin-13 receptor-targeted liposomal doxorubicin in the intracranial brain tumor model. Mol Cancer Ther (2009) 1.04
Regulation of the copper chaperone CCS by XIAP-mediated ubiquitination. Mol Cell Biol (2010) 1.03
Effects of ischemic preconditioning and bevacizumab on apoptosis and vascular permeability following retinal ischemia-reperfusion injury. Invest Ophthalmol Vis Sci (2010) 1.02
A transmural pressure gradient induces mechanical and biological adaptive responses in endothelial cells. Am J Physiol Heart Circ Physiol (2003) 1.01
Insulin promotes rat retinal neuronal cell survival in a p70S6K-dependent manner. J Biol Chem (2003) 1.00
Novel atypical PKC inhibitors prevent vascular endothelial growth factor-induced blood-retinal barrier dysfunction. Biochem J (2012) 1.00
Pharmacologic manipulation of sphingosine kinase in retinal endothelial cells: implications for angiogenic ocular diseases. Invest Ophthalmol Vis Sci (2006) 0.99
Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1). J Biol Chem (2012) 0.99
Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-element. Exp Eye Res (2008) 0.98
Occludin independently regulates permeability under hydrostatic pressure and cell division in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (2008) 0.97
Novel potential mechanisms for diabetic macular edema: leveraging new investigational approaches. Curr Diab Rep (2008) 0.96
Alterations in expression of angiopoietins and the Tie-2 receptor in the retina of streptozotocin induced diabetic rats. Mol Vis (2004) 0.94
Using the past to inform the future: anti-VEGF therapy as a road map to develop novel therapies for diabetic retinopathy. Diabetes (2013) 0.94
Ablation of 4E-BP1/2 prevents hyperglycemia-mediated induction of VEGF expression in the rodent retina and in Muller cells in culture. Diabetes (2010) 0.93
The occludin and ZO-1 complex, defined by small angle X-ray scattering and NMR, has implications for modulating tight junction permeability. Proc Natl Acad Sci U S A (2012) 0.93
A prize catch for diabetic retinopathy. Nat Med (2007) 0.92
Shear stress regulates HUVEC hydraulic conductivity by occludin phosphorylation. Ann Biomed Eng (2005) 0.86
Occludin localizes to centrosomes and modifies mitotic entry. J Biol Chem (2011) 0.84
VEGF increases paracellular transport without altering the solvent-drag reflection coefficient. Microvasc Res (2004) 0.84
Mixing ALD/MLD-grown ZnO and Zn-4-aminophenol layers into various thin-film structures. Dalton Trans (2013) 0.82
Mechanism of metabolic stroke and spontaneous cerebral hemorrhage in glutaric aciduria type I. Acta Neuropathol Commun (2014) 0.80
Polychromatic angiography for the assessment of VEGF-induced BRB dysfunction in the rabbit retina. Invest Ophthalmol Vis Sci (2013) 0.80
Phosphorylation site mapping of endogenous proteins: a combined MS and bioinformatics approach. J Proteome Res (2009) 0.79
A three-pore model describes transport properties of bovine retinal endothelial cells in normal and elevated glucose. Invest Ophthalmol Vis Sci (2011) 0.78
A role for systemic inflammation in diabetic retinopathy. Invest Ophthalmol Vis Sci (2013) 0.77
Atomic/molecular layer deposited thin-film alloys of Ti-4,4'-oxydianiline hybrid-TiO2 with tunable properties. Dalton Trans (2012) 0.76
Synthesis and structure-activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors. Bioorg Med Chem Lett (2013) 0.75
Ruboxistaurin for diabetic retinopathy. Ophthalmology (2006) 0.75
New insights for glutaric aciduria type I. Brain (2006) 0.75