Published in Dev Growth Differ on December 07, 2007
Secreted and transmembrane wnt inhibitors and activators. Cold Spring Harb Perspect Biol (2013) 2.01
Cellular signaling and biological functions of R-spondins. Cell Signal (2011) 1.25
Atlas of Wnt and R-spondin gene expression in the developing male mouse lower urogenital tract. Dev Dyn (2011) 1.14
The R-spondin family of proteins: emerging regulators of WNT signaling. Int J Biochem Cell Biol (2012) 1.09
Wnt11 promotes osteoblast maturation and mineralization through R-spondin 2. J Biol Chem (2009) 1.01
The canonical Wnt signaling activator, R-spondin2, regulates craniofacial patterning and morphogenesis within the branchial arch through ectodermal-mesenchymal interaction. Dev Biol (2011) 1.00
Loss-of-function point mutations and two-furin domain derivatives provide insights about R-spondin2 structure and function. Cell Signal (2009) 0.90
Recombinant R-spondin2 and Wnt3a up- and down-regulate novel target genes in C57MG mouse mammary epithelial cells. PLoS One (2012) 0.86
Secreted factor R-Spondin 2 is involved in refinement of patterning of the mammalian cochlea. Dev Dyn (2013) 0.84
Identification and Functional Characterization of RSPO2 as a Susceptibility Gene for Ossification of the Posterior Longitudinal Ligament of the Spine. Am J Hum Genet (2016) 0.77
R-Spondins Are Expressed by the Intestinal Stroma and are Differentially Regulated during Citrobacter rodentium- and DSS-Induced Colitis in Mice. PLoS One (2016) 0.76
Different regulation of limb development by p63 transcript variants. PLoS One (2017) 0.75
R-spondin 2 promotes acetylcholine receptor clustering at the neuromuscular junction via Lgr5. Sci Rep (2016) 0.75
The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass. Dev Cell (2009) 5.19
Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis. Nat Cell Biol (2007) 3.85
IL-33 is a crucial amplifier of innate rather than acquired immunity. Proc Natl Acad Sci U S A (2010) 3.07
Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos. Mech Dev (2007) 2.29
Intrinsic transition of embryonic stem-cell differentiation into neural progenitors. Nature (2011) 2.29
HuC:Kaede, a useful tool to label neural morphologies in networks in vivo. Genesis (2006) 2.26
Laterotopic representation of left-right information onto the dorso-ventral axis of a zebrafish midbrain target nucleus. Curr Biol (2005) 2.03
MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci (2011) 2.03
Illuminating cell-cycle progression in the developing zebrafish embryo. Proc Natl Acad Sci U S A (2009) 1.88
Temporally regulated asymmetric neurogenesis causes left-right difference in the zebrafish habenular structures. Dev Cell (2007) 1.86
An analysis of skeletal development in osteoblast-specific and chondrocyte-specific runt-related transcription factor-2 (Runx2) knockout mice. J Bone Miner Res (2013) 1.85
The habenula is crucial for experience-dependent modification of fear responses in zebrafish. Nat Neurosci (2010) 1.82
Genetic single-cell mosaic analysis implicates ephrinB2 reverse signaling in projections from the posterior tectum to the hindbrain in zebrafish. J Neurosci (2007) 1.80
N-cadherin mediates retinal lamination, maintenance of forebrain compartments and patterning of retinal neurites. Development (2003) 1.79
Comparative functional genomics revealed conservation and diversification of three enhancers of the isl1 gene for motor and sensory neuron-specific expression. Dev Biol (2005) 1.72
Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance. J Exp Med (2008) 1.63
Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways. Development (2005) 1.62
Mutations in prickle orthologs cause seizures in flies, mice, and humans. Am J Hum Genet (2011) 1.60
Redundant roles of Tead1 and Tead2 in notochord development and the regulation of cell proliferation and survival. Mol Cell Biol (2008) 1.59
R-spondin3 is required for mouse placental development. Dev Biol (2006) 1.58
Establishment of conditional reporter mouse lines at ROSA26 locus for live cell imaging. Genesis (2011) 1.54
The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice. J Clin Invest (2012) 1.54
Forkhead transcription factor FoxO1 in adipose tissue regulates energy storage and expenditure. Diabetes (2007) 1.53
Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis. Development (2006) 1.50
Flow cytometric isolation and clonal identification of self-renewing bipotent hepatic progenitor cells in adult mouse liver. Hepatology (2008) 1.41
The c-Jun N-terminal kinase activator dual leucine zipper kinase regulates axon growth and neuronal migration in the developing cerebral cortex. J Neurosci (2006) 1.40
The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance. J Clin Invest (2013) 1.39
Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse. Hum Mol Genet (2011) 1.36
How does Fgf signaling from the isthmic organizer induce midbrain and cerebellum development? Dev Growth Differ (2004) 1.35
The Zebrafish trilobite gene is essential for tangential migration of branchiomotor neurons. Dev Biol (2002) 1.33
Retinoic acid-metabolizing enzyme Cyp26a1 is essential for determining territories of hindbrain and spinal cord in zebrafish. Dev Biol (2005) 1.32
From the olfactory bulb to higher brain centers: genetic visualization of secondary olfactory pathways in zebrafish. J Neurosci (2009) 1.30
Mouse prickle1, the homolog of a PCP gene, is essential for epiblast apical-basal polarity. Proc Natl Acad Sci U S A (2009) 1.29
TIM1 is an endogenous ligand for LMIR5/CD300b: LMIR5 deficiency ameliorates mouse kidney ischemia/reperfusion injury. J Exp Med (2010) 1.29
Identification of the zebrafish ventral habenula as a homolog of the mammalian lateral habenula. J Neurosci (2010) 1.26
Dual roles of zygotic and maternal Scribble1 in neural migration and convergent extension movements in zebrafish embryos. Development (2005) 1.26
The zebrafish-secreted matrix protein you/scube2 is implicated in long-range regulation of hedgehog signaling. Curr Biol (2005) 1.26
Frizzled3a and Celsr2 function in the neuroepithelium to regulate migration of facial motor neurons in the developing zebrafish hindbrain. Development (2006) 1.26
Agonist-independent GPCR activity regulates anterior-posterior targeting of olfactory sensory neurons. Cell (2013) 1.21
Neutrophil direction sensing and superoxide production linked by the GTPase-activating protein GIT2. Nat Immunol (2006) 1.21
Lhx2 mediates the activity of Six3 in zebrafish forebrain growth. Dev Biol (2005) 1.20
Meiosis-specific cohesin mediates homolog recognition in mouse spermatocytes. Genes Dev (2014) 1.20
Regulation of Otx2 expression and its functions in mouse forebrain and midbrain. Development (2004) 1.17
Targeted disruption of the mouse ELYS gene results in embryonic death at peri-implantation development. Genes Cells (2004) 1.17
Draxin, a repulsive guidance protein for spinal cord and forebrain commissures. Science (2009) 1.17
Role of Lmx1b and Wnt1 in mesencephalon and metencephalon development. Development (2002) 1.16
ang is a novel gene expressed in early neuroectoderm, but its null mutant exhibits no obvious phenotype. Gene Expr Patterns (2004) 1.16
Repulsive guidance molecule plays multiple roles in neuronal differentiation and axon guidance. J Neurosci (2006) 1.16
The receptor LMIR3 negatively regulates mast cell activation and allergic responses by binding to extracellular ceramide. Immunity (2012) 1.15
Visualization of cell cycle in mouse embryos with Fucci2 reporter directed by Rosa26 promoter. Development (2012) 1.13
Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation. Development (2008) 1.13
Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm. Development (2004) 1.13
Putative "stemness" gene jam-B is not required for maintenance of stem cell state in embryonic, neural, or hematopoietic stem cells. Mol Cell Biol (2006) 1.12
Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex. Development (2005) 1.12
A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors. Nat Neurosci (2012) 1.12
Prox1 postmitotically defines dentate gyrus cells by specifying granule cell identity over CA3 pyramidal cell fate in the hippocampus. Development (2012) 1.11
Irbit mediates synergy between ca(2+) and cAMP signaling pathways during epithelial transport in mice. Gastroenterology (2013) 1.10
Migration of zebrafish spinal motor nerves into the periphery requires multiple myotome-derived cues. Dev Biol (2002) 1.10
Two divergent slit1 genes in zebrafish. Dev Dyn (2003) 1.10
Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme. Proc Natl Acad Sci U S A (2010) 1.09
Nardilysin regulates axonal maturation and myelination in the central and peripheral nervous system. Nat Neurosci (2009) 1.08
The hedgehog-PKA pathway regulates two distinct steps of the differentiation of retinal ganglion cells: the cell-cycle exit of retinoblasts and their neuronal maturation. Development (2005) 1.08
Phylogeny and ontogeny of the habenular structure. Front Neurosci (2011) 1.08
Molecular characterization of the subnuclei in rat habenula. J Comp Neurol (2012) 1.07
A murine model of neonatal diabetes mellitus in Glis3-deficient mice. FEBS Lett (2009) 1.07
Foxp1 and lhx1 coordinate motor neuron migration with axon trajectory choice by gating Reelin signalling. PLoS Biol (2010) 1.07
Canopy1, a novel regulator of FGF signaling around the midbrain-hindbrain boundary in zebrafish. Curr Biol (2006) 1.07
Glioblastoma formation from cell population depleted of Prominin1-expressing cells. PLoS One (2009) 1.05
Chemokine signaling guides axons within the retina in zebrafish. J Neurosci (2005) 1.03
Involvement of Islet-2 in the Slit signaling for axonal branching and defasciculation of the sensory neurons in embryonic zebrafish. Mech Dev (2004) 1.03
Cartilage acidic protein-1B (LOTUS), an endogenous Nogo receptor antagonist for axon tract formation. Science (2011) 1.03
Differential roles of Epac in regulating cell death in neuronal and myocardial cells. J Biol Chem (2010) 1.02
Arid5a controls IL-6 mRNA stability, which contributes to elevation of IL-6 level in vivo. Proc Natl Acad Sci U S A (2013) 1.02
Angiopoietin-1 guides directional angiogenesis through integrin αvβ5 signaling for recovery of ischemic retinopathy. Sci Transl Med (2013) 1.02
Neuroepithelial cells require fucosylated glycans to guide the migration of vagus motor neuron progenitors in the developing zebrafish hindbrain. Development (2009) 1.01
Gene disruption/knock-in analysis of mONT3: vector construction by employing both in vivo and in vitro recombinations. Int J Dev Biol (2005) 1.00
NBRP databases: databases of biological resources in Japan. Nucleic Acids Res (2009) 0.99
Canopy1, a positive feedback regulator of FGF signaling, controls progenitor cell clustering during Kupffer's vesicle organogenesis. Proc Natl Acad Sci U S A (2011) 0.99
Robo2 is required for establishment of a precise glomerular map in the zebrafish olfactory system. Development (2005) 0.98
Development of the mouse amygdala as revealed by enhanced green fluorescent protein gene transfer by means of in utero electroporation. J Comp Neurol (2009) 0.98
The Fgf8 signal causes cerebellar differentiation by activating the Ras-ERK signaling pathway. Development (2004) 0.97
Lymphotoxin signal promotes thymic organogenesis by eliciting RANK expression in the embryonic thymic stroma. J Immunol (2011) 0.97
Mutation of cGMP phosphodiesterase 6alpha'-subunit gene causes progressive degeneration of cone photoreceptors in zebrafish. Mech Dev (2008) 0.97
Gene silencing in chick embryos with a vector-based small interfering RNA system. Dev Growth Differ (2003) 0.97
Roles of noncanonical Wnt/PCP pathway genes in neuronal migration and neurulation in zebrafish. Zebrafish (2009) 0.97
Dual roles of Notch in regulation of apically restricted mitosis and apicobasal polarity of neuroepithelial cells. Neuron (2011) 0.97
Local caspase activation interacts with Slit-Robo signaling to restrict axonal arborization. J Cell Biol (2013) 0.96
Short limbs, cleft palate, and delayed formation of flat proliferative chondrocytes in mice with targeted disruption of a putative protein kinase gene, Pkdcc (AW548124). Dev Dyn (2009) 0.95
Targeted disruption of Sept3, a heteromeric assembly partner of Sept5 and Sept7 in axons, has no effect on developing CNS neurons. J Neurochem (2007) 0.95
Asymmetric distribution of dynamic calcium signals in the node of mouse embryo during left-right axis formation. Dev Biol (2013) 0.95
Characterization of neural stem cells and their progeny in the adult zebrafish optic tectum. Dev Biol (2010) 0.95
Osterix regulates calcification and degradation of chondrogenic matrices through matrix metalloproteinase 13 (MMP13) expression in association with transcription factor Runx2 during endochondral ossification. J Biol Chem (2012) 0.94
Loss of a Rho-regulated actin nucleator, mDia2, impairs cytokinesis during mouse fetal erythropoiesis. Cell Rep (2013) 0.93
A type I DnaJ homolog, DjA1, regulates androgen receptor signaling and spermatogenesis. EMBO J (2005) 0.93
Chemerin regulates β-cell function in mice. Sci Rep (2011) 0.93
Isx participates in the maintenance of vitamin A metabolism by regulation of beta-carotene 15,15'-monooxygenase (Bcmo1) expression. J Biol Chem (2007) 0.93
A mouse reporter line to conditionally mark nuclei and cell membranes for in vivo live-imaging. Genesis (2011) 0.92
Molecular identification of t(w5): Vps52 promotes pluripotential cell differentiation through cell-cell interactions. Cell Rep (2012) 0.91
Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis. Dev Biol (2012) 0.91