Published in Curr Opin Biotechnol on December 21, 2007
The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line. Nat Biotechnol (2011) 2.87
A review of the mammalian unfolded protein response. Biotechnol Bioeng (2011) 1.83
Generation and screening of Pichia pastoris strains with enhanced protein production by use of microengraving. Appl Environ Microbiol (2011) 0.88
Sustained productivity in recombinant Chinese hamster ovary (CHO) cell lines: proteome analysis of the molecular basis for a process-related phenotype. BMC Biotechnol (2011) 0.83
Combination of FACS and homologous recombination for the generation of stable and high-expression engineered cell lines. PLoS One (2014) 0.78
Advancement in bioprocess technology: parallels between microbial natural products and cell culture biologics. J Ind Microbiol Biotechnol (2017) 0.76
The relationship between mTOR signalling pathway and recombinant antibody productivity in CHO cell lines. BMC Biotechnol (2014) 0.76
A control strategy to investigate the relationship between specific productivity and high-mannose glycoforms in CHO cells. Appl Microbiol Biotechnol (2016) 0.75
Development of Genetically Modified Chinese Hamster Ovary Host Cells for the Enhancement of Recombinant Tissue Plasminogen Activator Expression. Malays J Med Sci (2016) 0.75
Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells. J Clin Invest (2002) 3.90
A kinetic model of quantitative real-time polymerase chain reaction. Biotechnol Bioeng (2005) 1.75
Uncovering genes with divergent mRNA-protein dynamics in Streptomyces coelicolor. PLoS One (2008) 1.46
Comparative transcriptome analysis of embryonic and adult stem cells with extended and limited differentiation capacity. Genome Biol (2007) 1.41
Improved development of human embryonic stem cell-derived embryoid bodies by stirred vessel cultivation. Biotechnol Bioeng (2006) 1.40
Engineering cell metabolism for high-density cell culture via manipulation of sugar transport. J Biotechnol (2007) 1.34
Structural polarity and functional bile canaliculi in rat hepatocyte spheroids. Exp Cell Res (2002) 1.33
Convergent transcription confers a bistable switch in Enterococcus faecalis conjugation. Proc Natl Acad Sci U S A (2011) 1.30
Growth cones turn and migrate up an immobilized gradient of the laminin IKVAV peptide. J Neurobiol (2005) 1.26
Endothelium-mediated hepatocyte recruitment in the establishment of liver-like tissue in vitro. Tissue Eng (2006) 1.23
Culture systems for pluripotent stem cells. J Biosci Bioeng (2005) 1.19
Defined conditions for development of functional hepatic cells from human embryonic stem cells. Stem Cells Dev (2005) 1.16
Genome-wide transcriptome analysis reveals that a pleiotropic antibiotic regulator, AfsS, modulates nutritional stress response in Streptomyces coelicolor A3(2). BMC Genomics (2008) 1.12
An auxin surge following fertilization in carrots: a mechanism for regulating plant totipotency. Planta (2002) 1.11
A diffusion-reaction model for DNA microarray assays. J Biotechnol (2004) 1.07
Tweaking biological switches through a better understanding of bistability behavior. Curr Opin Biotechnol (2008) 1.06
Multitagging proteomic strategy to estimate protein turnover rates in dynamic systems. J Proteome Res (2010) 1.06
Transcriptome and proteome profiling to understanding the biology of high productivity CHO cells. Mol Biotechnol (2006) 1.05
A framework to analyze multiple time series data: a case study with Streptomyces coelicolor. J Ind Microbiol Biotechnol (2005) 1.05
Systems analysis of N-glycan processing in mammalian cells. PLoS One (2007) 1.03
Antagonistic self-sensing and mate-sensing signaling controls antibiotic-resistance transfer. Proc Natl Acad Sci U S A (2013) 1.03
Transcriptional response of Escherichia coli to temperature shift. Biotechnol Prog (2005) 1.03
Transcriptome and proteome analysis of Chinese hamster ovary cells under low temperature and butyrate treatment. J Biotechnol (2009) 1.03
Comparative genomic hybridizations reveal absence of large Streptomyces coelicolor genomic islands in Streptomyces lividans. BMC Genomics (2007) 1.02
Non-linear reduction for kinetic models of metabolic reaction networks. Metab Eng (2004) 1.02
Transcriptome dynamics-based operon prediction and verification in Streptomyces coelicolor. Nucleic Acids Res (2007) 1.00
On metabolic shift to lactate consumption in fed-batch culture of mammalian cells. Metab Eng (2012) 0.99
Fedbatch culture and dynamic nutrient feeding. Adv Biochem Eng Biotechnol (2006) 0.99
Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells. PLoS One (2010) 0.99
Three-dimensional co-culture of hepatocytes and stellate cells. Cytotechnology (2004) 0.98
A bistable gene switch for antibiotic biosynthesis: the butyrolactone regulon in Streptomyces coelicolor. PLoS One (2008) 0.97
Analysis of cellular metabolism of hybridoma cells at distinct physiological states. J Biosci Bioeng (2003) 0.97
Genomic and proteomic exploration of CHO and hybridoma cells under sodium butyrate treatment. Biotechnol Bioeng (2008) 0.97
Reaching the depth of the Chinese hamster ovary cell transcriptome. Biotechnol Bioeng (2010) 0.96
Mining manufacturing data for discovery of high productivity process characteristics. J Biotechnol (2010) 0.96
Conserved microRNAs in Chinese hamster ovary cell lines. Biotechnol Bioeng (2011) 0.95
Mining bioprocess data: opportunities and challenges. Trends Biotechnol (2008) 0.94
An analysis of the use of genomic DNA as a universal reference in two channel DNA microarrays. BMC Genomics (2005) 0.94
Isolation and characterization of a novel population of progenitor cells from unmanipulated rat liver. Liver Transpl (2008) 0.94
Spheroid culture for enhanced differentiation of human embryonic stem cells to hepatocyte-like cells. Stem Cells Dev (2013) 0.93
Deletion of the signalling molecule synthase ScbA has pleiotropic effects on secondary metabolite biosynthesis, morphological differentiation and primary metabolism in Streptomyces coelicolor A3(2). Microb Biotechnol (2010) 0.93
Molecular portrait of high productivity in recombinant NS0 cells. Biotechnol Bioeng (2007) 0.93
Glucose metabolism in mammalian cell culture: new insights for tweaking vintage pathways. Trends Biotechnol (2010) 0.92
Biofilm growth alters regulation of conjugation by a bacterial pheromone. Mol Microbiol (2011) 0.91
Large scale gene expression profiling of metabolic shift of mammalian cells in culture. J Biotechnol (2004) 0.91
Engineering cells for cell culture bioprocessing--physiological fundamentals. Adv Biochem Eng Biotechnol (2006) 0.91
Activation of hypoxic response in human embryonic stem cell-derived embryoid bodies. Exp Biol Med (Maywood) (2008) 0.91
Isolation procedure and characterization of multipotent adult progenitor cells from rat bone marrow. Methods Mol Biol (2010) 0.90
EST sequencing for gene discovery in Chinese hamster ovary cells. Biotechnol Bioeng (2005) 0.90
Advancing mammalian cell culture engineering using genome-scale technologies. Trends Biotechnol (2007) 0.89
Low-glutamine fed-batch cultures of 293-HEK serum-free suspension cells for adenovirus production. Biotechnol Prog (2003) 0.88
A mathematical model for suppression subtractive hybridization. Comp Funct Genomics (2002) 0.88
Genome-wide inference of regulatory networks in Streptomyces coelicolor. BMC Genomics (2010) 0.88
Bistability versus bimodal distributions in gene regulatory processes from population balance. PLoS Comput Biol (2011) 0.88
Comparative transcriptional analysis of mouse hybridoma and recombinant Chinese hamster ovary cells undergoing butyrate treatment. J Biosci Bioeng (2007) 0.88
Developing genomic platforms for Chinese hamster ovary cells. Biotechnol Adv (2009) 0.87
A scaffold for the Chinese hamster genome. Biotechnol Bioeng (2007) 0.86
Stem cell culture engineering - process scale up and beyond. Biotechnol J (2011) 0.85
Quality assessment of cross-species hybridization of CHO transcriptome on a mouse DNA oligo microarray. Biotechnol Bioeng (2008) 0.85
A Boolean algorithm for reconstructing the structure of regulatory networks. Metab Eng (2004) 0.85
Global assessment of protein turnover in recombinant antibody producing myeloma cells. J Biotechnol (2010) 0.84
MAPC culture conditions support the derivation of cells with nascent hypoblast features from bone marrow and blastocysts. J Mol Cell Biol (2012) 0.84
Multivariate analysis of cell culture bioprocess data--lactate consumption as process indicator. J Biotechnol (2012) 0.83
Titanium-enriched hydroxyapatite-gelatin scaffolds with osteogenically differentiated progenitor cell aggregates for calvaria bone regeneration. Tissue Eng Part A (2013) 0.82
A scalable approach for discovering conserved active subnetworks across species. PLoS Comput Biol (2010) 0.82
Global insights into the Chinese hamster and CHO cell transcriptomes. Biotechnol Bioeng (2015) 0.82
Reverting cholesterol auxotrophy of NS0 cells by altering epigenetic gene silencing. Biotechnol Bioeng (2006) 0.82
GlycoVis: visualizing glycan distribution in the protein N-glycosylation pathway in mammalian cells. Biotechnol Bioeng (2006) 0.81
Comparative transcriptome analysis to unveil genes affecting recombinant protein productivity in mammalian cells. Biotechnol Bioeng (2009) 0.81
Enhanced differentiation of adult bone marrow-derived stem cells to liver lineage in aggregate culture. Tissue Eng Part A (2011) 0.81
Genome sequence of the curdlan-producing Agrobacterium sp. strain ATCC 31749. J Bacteriol (2011) 0.81
Convergent transcription in the butyrolactone regulon in Streptomyces coelicolor confers a bistable genetic switch for antibiotic biosynthesis. PLoS One (2011) 0.80
17Beta-hydroxysteroid dehydrogenase type 7 (Hsd17b7) reverts cholesterol auxotrophy in NS0 cells. J Biotechnol (2005) 0.80
Hypothermic maintenance of hepatocyte spheroids. Cell Transplant (2005) 0.80
Permeability and reactivity of Thermotoga maritima in latex bimodal blend coatings at 80 degrees C: a model high temperature biocatalytic coating. Extremophiles (2005) 0.80
Role of intracellular stochasticity in biofilm growth. Insights from population balance modeling. PLoS One (2013) 0.79
Dexamethasone effects on rat hepatocyte spheroid formation and function. Tissue Eng (2005) 0.79
MODELING OF GENE REGULATORY PROCESSES BY POPULATION MEDIATED SIGNALING. NEW APPLICATIONS OF POPULATION BALANCES. Chem Eng Sci (2011) 0.78
Toward genomic cell culture engineering. Cytotechnology (2006) 0.78
The road to regenerative liver therapies: the triumphs, trials and tribulations. Biotechnol Adv (2013) 0.78
Large-scale gene expression analysis of cholesterol dependence in NS0 cells. Biotechnol Bioeng (2005) 0.78
Transcriptome dynamics of transgene amplification in Chinese hamster ovary cells. Biotechnol Bioeng (2013) 0.77
Dynamic gene expression for metabolic engineering of mammalian cells in culture. Metab Eng (2013) 0.77
Unveiling steady-state multiplicity in hybridoma cultures: the cybernetic approach. Biotechnol Bioeng (2003) 0.76
Characterization of a hollow fiber bioartificial liver device. Artif Organs (2005) 0.76
Exploring the transcriptome space of a recombinant BHK cell line through next generation sequencing. Biotechnol Bioeng (2013) 0.76
Differential gene expression analysis during porcine hepatocyte spheroid formation. Mamm Genome (2002) 0.76
Mining transcriptome data for function-trait relationship of hyper productivity of recombinant antibody. Biotechnol Bioeng (2009) 0.76
Cell line development for biomanufacturing processes: recent advances and an outlook. Biotechnol Lett (2015) 0.75
Stem cell science has made major strides in the last few years. Introduction. Biotechnol Adv (2013) 0.75
TimeView: for comparative gene expression analysis. Appl Bioinformatics (2006) 0.75
Elmer L. Gaden, Jr. Tribute. Biotechnol Bioeng (2012) 0.75
Transcriptome data analysis for cell culture processes. Adv Biochem Eng Biotechnol (2012) 0.75
Implementing high-temperature short-time media treatment in commercial-scale cell culture manufacturing processes. Appl Microbiol Biotechnol (2013) 0.75
Sustaining a bioartificial liver under hypothermic conditions. Tissue Eng (2005) 0.75