Published in J Biol Chem on December 14, 2007
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Regulation of the intrinsic apoptosis pathway by reactive oxygen species. Antioxid Redox Signal (2012) 1.27
Quantitative analysis of ERK2 interactions with substrate proteins: roles for kinase docking domains and activity in determining binding affinity. J Biol Chem (2010) 1.03
Characterization of ERK docking domain inhibitors that induce apoptosis by targeting Rsk-1 and caspase-9. BMC Cancer (2011) 0.88
Development of extracellular signal-regulated kinase inhibitors. Curr Top Med Chem (2009) 0.84
Using Caenorhabditis elegans as a model organism for evaluating extracellular signal-regulated kinase docking domain inhibitors. J Cell Commun Signal (2008) 0.81
The S-nitrosylation status of PCNA localized in cytosol impacts the apoptotic pathway in a Parkinson's disease paradigm. PLoS One (2015) 0.78
The ClusPro web server for protein-protein docking. Nat Protoc (2017) 0.77
Small-molecule inhibitors of ERK-mediated immediate early gene expression and proliferation of melanoma cells expressing mutated BRaf. Biochem J (2015) 0.77
Inhibition of caspase-9 aggravates acute liver injury through suppression of cytoprotective autophagy. Sci Rep (2016) 0.76
The molecular mechanisms underlying the ERα-36-mediated signaling in breast cancer. Oncogene (2016) 0.75
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Multiple proteolytic events in caspase-6 self-activation impact conformations of discrete structural regions. Proc Natl Acad Sci U S A (2017) 0.75
Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK. Nat Cell Biol (2003) 2.63
Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest. EMBO J (2010) 2.33
Phosphorylation of caspase-9 by CDK1/cyclin B1 protects mitotic cells against apoptosis. Mol Cell (2007) 2.12
Structure and functionality in flavivirus NS-proteins: perspectives for drug design. Antiviral Res (2009) 1.87
Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosis. Cell Res (2008) 1.73
Apoptosis and autophagy: Regulation of caspase-9 by phosphorylation. FEBS J (2009) 1.71
Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells. Curr Biol (2002) 1.40
DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system. Biochem J (2005) 1.37
Cell-cycle control in the face of damage--a matter of life or death. Trends Cell Biol (2009) 1.30
Phosphorylation regulates the dynamic interaction of RCC1 with chromosomes during mitosis. Curr Biol (2004) 1.30
Crystal structure of a novel conformational state of the flavivirus NS3 protein: implications for polyprotein processing and viral replication. J Virol (2009) 1.29
DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine. FEBS J (2008) 1.26
Clathrin recruits phosphorylated TACC3 to spindle poles for bipolar spindle assembly and chromosome alignment. J Cell Sci (2010) 1.22
Structure of the leukemia oncogene LMO2: implications for the assembly of a hematopoietic transcription factor complex. Blood (2010) 1.20
Many fingers on the mitotic trigger: post-translational regulation of the Cdc25C phosphatase. Cell Cycle (2004) 1.19
Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c. J Biol Chem (2005) 1.08
Regulation of Cdc2/cyclin B activation in Xenopus egg extracts via inhibitory phosphorylation of Cdc25C phosphatase by Ca(2+)/calmodulin-dependent protein [corrected] kinase II. Mol Biol Cell (2003) 1.07
Role of importin-beta in the control of nuclear envelope assembly by Ran. Curr Biol (2002) 1.06
Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly. Eur J Cell Biol (2002) 1.03
Regulation of Claspin degradation by the ubiquitin-proteosome pathway during the cell cycle and in response to ATR-dependent checkpoint activation. FEBS Lett (2006) 1.03
Semi-automated microseeding of nanolitre crystallization experiments. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 1.01
Dephosphorylation of the inhibitory phosphorylation site S287 in Xenopus Cdc25C by protein phosphatase-2A is inhibited by 14-3-3 binding. FEBS Lett (2002) 1.00
Structural basis of mechanochemical coupling in a hexameric molecular motor. J Biol Chem (2007) 0.98
The importin-beta P446L dominant-negative mutant protein loses RanGTP binding ability and blocks the formation of intact nuclear envelope. J Cell Sci (2002) 0.97
Concerted action of the PHD, chromo and motor domains regulates the human chromatin remodelling ATPase CHD4. FEBS Lett (2012) 0.96
hnRNP-U is a specific DNA-dependent protein kinase substrate phosphorylated in response to DNA double-strand breaks. Biochem Biophys Res Commun (2009) 0.93
Cell biology: Ran, mitosis and the cancer connection. Curr Biol (2006) 0.93
Plate tectonics of virus shell assembly and reorganization in phage φ8, a distant relative of mammalian reoviruses. Structure (2013) 0.93
RCC1 isoforms differ in their affinity for chromatin, molecular interactions and regulation by phosphorylation. J Cell Sci (2007) 0.92
Regulation of caspase 9 through phosphorylation by protein kinase C zeta in response to hyperosmotic stress. Mol Cell Biol (2005) 0.91
Nuclear pores: sowing the seeds of assembly on the chromatin landscape. Curr Biol (2003) 0.91
The methylated N-terminal tail of RCC1 is required for stabilisation of its interaction with chromatin by Ran in live cells. BMC Cell Biol (2010) 0.90
p38alpha- and DYRK1A-dependent phosphorylation of caspase-9 at an inhibitory site in response to hyperosmotic stress. Cell Signal (2009) 0.90
Structural basis for LMO2-driven recruitment of the SCL:E47bHLH heterodimer to hematopoietic-specific transcriptional targets. Cell Rep (2013) 0.90
Microtubule assembly by the Apc protein is regulated by importin-beta--RanGTP. J Cell Sci (2010) 0.88
Destruction's our delight: controlling apoptosis during mitotic arrest. Cell Cycle (2010) 0.87
Chromatin-bound NLS proteins recruit membrane vesicles and nucleoporins for nuclear envelope assembly via importin-α/β. Cell Res (2012) 0.86
Cleavage of claspin by caspase-7 during apoptosis inhibits the Chk1 pathway. J Biol Chem (2005) 0.85
Dynamic localisation of Ran GTPase during the cell cycle. BMC Cell Biol (2009) 0.85
Tracking in atomic detail the functional specializations in viral RecA helicases that occur during evolution. Nucleic Acids Res (2013) 0.84
Structure of the DNA-bound T-box domain of human TBX1, a transcription factor associated with the DiGeorge syndrome. Proteins (2011) 0.83
Phosphorylation of Crm1 by CDK1-cyclin-B promotes Ran-dependent mitotic spindle assembly. J Cell Sci (2013) 0.83
Claspin is phosphorylated in the Chk1-binding domain by a kinase distinct from Chk1. Biochem Biophys Res Commun (2008) 0.81
The Crm de la crème of mitosis. Nat Cell Biol (2005) 0.81
A mechanism coupling cell division and the control of apoptosis. SEB Exp Biol Ser (2008) 0.81
The crystal structure of UMP kinase from Bacillus anthracis (BA1797) reveals an allosteric nucleotide-binding site. J Mol Biol (2008) 0.78
Purification, crystallization and preliminary X-ray analysis of a fusion of the LIM domains of LMO2 and the LID domain of Ldb1. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.77
Overcoming the false-minima problem in direct methods: structure determination of the packaging enzyme P4 from bacteriophage phi13. Acta Crystallogr D Biol Crystallogr (2005) 0.77
To the centre of the volcano. Workshop on the mechanisms of nucleocytoplasmic transport. EMBO Rep (2008) 0.75
Anchoring RCC1 by the tail. Nat Cell Biol (2007) 0.75