Published in Curr Biol on June 22, 2004
New insights into myosin evolution and classification. Proc Natl Acad Sci U S A (2006) 2.97
N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis. Nat Cell Biol (2007) 2.36
Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest. EMBO J (2010) 2.33
Dissecting the contribution of diffusion and interactions to the mobility of nuclear proteins. Biophys J (2005) 1.94
Condensed mitotic chromatin is accessible to transcription factors and chromatin structural proteins. J Cell Biol (2004) 1.86
The nuclear envelope. Cold Spring Harb Perspect Biol (2010) 1.64
A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging. EMBO J (2011) 1.54
Regulation of chromatin binding by a conformational switch in the tail of the Ran exchange factor RCC1. J Cell Biol (2008) 1.22
Distinct sequence elements of cyclin B1 promote localization to chromatin, centrosomes, and kinetochores during mitosis. Mol Biol Cell (2007) 1.13
Poc1A and Poc1B act together in human cells to ensure centriole integrity. J Cell Sci (2012) 0.94
Proteomics identification of nuclear Ran GTPase as an inhibitor of human VRK1 and VRK2 (vaccinia-related kinase) activities. Mol Cell Proteomics (2008) 0.92
The methylated N-terminal tail of RCC1 is required for stabilisation of its interaction with chromatin by Ran in live cells. BMC Cell Biol (2010) 0.90
Self-organization of intracellular gradients during mitosis. Cell Div (2010) 0.89
Substrate-specific regulation of ubiquitination by the anaphase-promoting complex. Cell Cycle (2011) 0.86
Nuclear reformation after mitosis requires downregulation of the Ran GTPase effector RanBP1 in mammalian cells. Chromosoma (2010) 0.86
Dynamic localisation of Ran GTPase during the cell cycle. BMC Cell Biol (2009) 0.85
RanBP1 governs spindle assembly by defining mitotic Ran-GTP production. Dev Cell (2014) 0.82
Nuclear transport factors: global regulation of mitosis. Curr Opin Cell Biol (2015) 0.81
Analyses of PDE-regulated phosphoproteomes reveal unique and specific cAMP-signaling modules in T cells. Proc Natl Acad Sci U S A (2017) 0.80
Determinants of human cyclin B1 association with mitotic chromosomes. PLoS One (2013) 0.79
Phosphorylation of Ran-binding protein-1 by Polo-like kinase-1 is required for interaction with Ran and early mitotic progression. J Biol Chem (2011) 0.78
Identification of the ISWI Chromatin Remodeling Complex of the Early Branching Eukaryote Trypanosoma brucei. J Biol Chem (2015) 0.78
Disruption of the ran system by cysteine oxidation of the nucleotide exchange factor RCC1. Mol Cell Biol (2014) 0.77
Revisiting chromatin binding of the Arabidopsis UV-B photoreceptor UVR8. BMC Plant Biol (2016) 0.77
Cell cycle-dependent binding modes of the ran exchange factor RCC1 to chromatin. Biophys J (2013) 0.76
The Ran Pathway in Drosophila melanogaster Mitosis. Front Cell Dev Biol (2015) 0.75
Three-dimensional context rather than NLS amino acid sequence determines importin α subtype specificity for RCC1. Nat Commun (2017) 0.75
Metadata matters: access to image data in the real world. J Cell Biol (2010) 12.49
The Open Microscopy Environment (OME) Data Model and XML file: open tools for informatics and quantitative analysis in biological imaging. Genome Biol (2005) 5.16
Aurora B regulates MCAK at the mitotic centromere. Dev Cell (2004) 4.94
OMERO: flexible, model-driven data management for experimental biology. Nat Methods (2012) 3.72
Cajal body dynamics and association with chromatin are ATP-dependent. Nat Cell Biol (2002) 3.28
Biological imaging software tools. Nat Methods (2012) 2.91
The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis. Mol Biol Cell (2004) 2.71
Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK. Nat Cell Biol (2003) 2.63
Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest. EMBO J (2010) 2.33
Mitotic mechanics: the auroras come into view. Curr Opin Cell Biol (2003) 2.31
Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics. Cell (2003) 2.20
Phosphorylation of caspase-9 by CDK1/cyclin B1 protects mitotic cells against apoptosis. Mol Cell (2007) 2.12
To 5D and beyond: quantitative fluorescence microscopy in the postgenomic era. Traffic (2002) 2.04
Evaluating performance in three-dimensional fluorescence microscopy. J Microsc (2007) 1.89
Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases. J Cell Biol (2010) 1.89
Ubiquitylation-dependent localization of PLK1 in mitosis. Nat Cell Biol (2013) 1.81
Time-lapse imaging reveals dynamic relocalization of PP1gamma throughout the mammalian cell cycle. Mol Biol Cell (2003) 1.78
Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosis. Cell Res (2008) 1.73
Apoptosis and autophagy: Regulation of caspase-9 by phosphorylation. FEBS J (2009) 1.71
ELYS/MEL-28 chromatin association coordinates nuclear pore complex assembly and replication licensing. Curr Biol (2007) 1.61
Measuring tubulin content in Toxoplasma gondii: a comparison of laser-scanning confocal and wide-field fluorescence microscopy. Proc Natl Acad Sci U S A (2002) 1.55
A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging. EMBO J (2011) 1.54
Sla1p couples the yeast endocytic machinery to proteins regulating actin dynamics. J Cell Sci (2002) 1.54
Macromolecular mobility inside the cell nucleus. Trends Cell Biol (2002) 1.53
Mitotic spindle orientation distinguishes stem cell and terminal modes of neuron production in the early spinal cord. Development (2007) 1.42
Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells. Curr Biol (2002) 1.40
Open tools for storage and management of quantitative image data. Methods Cell Biol (2008) 1.39
DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system. Biochem J (2005) 1.37
Sds22 regulates aurora B activity and microtubule-kinetochore interactions at mitosis. J Cell Biol (2010) 1.30
DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine. FEBS J (2008) 1.26
Bod1, a novel kinetochore protein required for chromosome biorientation. J Cell Biol (2007) 1.22
Clathrin recruits phosphorylated TACC3 to spindle poles for bipolar spindle assembly and chromosome alignment. J Cell Sci (2010) 1.22
Data management challenges in three-dimensional EM. Nat Struct Mol Biol (2012) 1.19
Many fingers on the mitotic trigger: post-translational regulation of the Cdc25C phosphatase. Cell Cycle (2004) 1.19
The Nup107-160 nucleoporin complex promotes mitotic events via control of the localization state of the chromosome passenger complex. Mol Biol Cell (2009) 1.15
A novel reporter of notch signalling indicates regulated and random Notch activation during vertebrate neurogenesis. BMC Biol (2011) 1.14
PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192. Dev Cell (2013) 1.12
A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formation. Bone (2009) 1.10
Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c. J Biol Chem (2005) 1.08
Regulation of Cdc2/cyclin B activation in Xenopus egg extracts via inhibitory phosphorylation of Cdc25C phosphatase by Ca(2+)/calmodulin-dependent protein [corrected] kinase II. Mol Biol Cell (2003) 1.07
Role of importin-beta in the control of nuclear envelope assembly by Ran. Curr Biol (2002) 1.06
Aurora A kinase activity is required for localization of TACC3/ch-TOG/clathrin inter-microtubule bridges. Commun Integr Biol (2011) 1.05
Temporal profiling of the chromatin proteome reveals system-wide responses to replication inhibition. Curr Biol (2008) 1.04
Regulation of Claspin degradation by the ubiquitin-proteosome pathway during the cell cycle and in response to ATR-dependent checkpoint activation. FEBS Lett (2006) 1.03
Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly. Eur J Cell Biol (2002) 1.03
Synthesis and activity of substituted 4-(indazol-3-yl)phenols as pathway-selective estrogen receptor ligands useful in the treatment of rheumatoid arthritis. J Med Chem (2004) 1.03
Phosphorylation by aurora-B negatively regulates survivin function during mitosis. Cell Cycle (2007) 1.02
Mechanical stress induces profound remodelling of keratin filaments and cell junctions in epidermolysis bullosa simplex keratinocytes. J Cell Sci (2004) 1.02
Dephosphorylation of the inhibitory phosphorylation site S287 in Xenopus Cdc25C by protein phosphatase-2A is inhibited by 14-3-3 binding. FEBS Lett (2002) 1.00
Quantitative analysis of digital microscope images. Methods Cell Biol (2007) 1.00
The importin-beta P446L dominant-negative mutant protein loses RanGTP binding ability and blocks the formation of intact nuclear envelope. J Cell Sci (2002) 0.97
Bod1 regulates protein phosphatase 2A at mitotic kinetochores. Nat Commun (2013) 0.97
hnRNP-U is a specific DNA-dependent protein kinase substrate phosphorylated in response to DNA double-strand breaks. Biochem Biophys Res Commun (2009) 0.93
Cell biology: Ran, mitosis and the cancer connection. Curr Biol (2006) 0.93
Web-based visualisation and analysis of 3D electron-microscopy data from EMDB and PDB. J Struct Biol (2013) 0.93
RCC1 isoforms differ in their affinity for chromatin, molecular interactions and regulation by phosphorylation. J Cell Sci (2007) 0.92
OMX: a new platform for multimodal, multichannel wide-field imaging. Cold Spring Harb Protoc (2011) 0.91
Regulation of caspase 9 through phosphorylation by protein kinase C zeta in response to hyperosmotic stress. Mol Cell Biol (2005) 0.91
(S)-N-(5-Chlorothiophene-2-sulfonyl)-beta,beta-diethylalaninol a Notch-1-sparing gamma-secretase inhibitor. Bioorg Med Chem Lett (2008) 0.91
Nuclear pores: sowing the seeds of assembly on the chromatin landscape. Curr Biol (2003) 0.91
The methylated N-terminal tail of RCC1 is required for stabilisation of its interaction with chromatin by Ran in live cells. BMC Cell Biol (2010) 0.90
p38alpha- and DYRK1A-dependent phosphorylation of caspase-9 at an inhibitory site in response to hyperosmotic stress. Cell Signal (2009) 0.90
Quinic acid derivatives as sialyl Lewis(x)-mimicking selectin inhibitors: design, synthesis, and crystal structure in complex with E-selectin. J Med Chem (2005) 0.90
The docking interaction of caspase-9 with ERK2 provides a mechanism for the selective inhibitory phosphorylation of caspase-9 at threonine 125. J Biol Chem (2007) 0.89
Microtubule assembly by the Apc protein is regulated by importin-beta--RanGTP. J Cell Sci (2010) 0.88
How to be a mitotic chromosome. Chromosome Res (2011) 0.87
Selective androgen receptor modulators for frailty and osteoporosis. Curr Opin Investig Drugs (2007) 0.87
High-resolution live imaging of cell behavior in the developing neuroepithelium. J Vis Exp (2012) 0.87
Destruction's our delight: controlling apoptosis during mitotic arrest. Cell Cycle (2010) 0.87
Chromatin-bound NLS proteins recruit membrane vesicles and nucleoporins for nuclear envelope assembly via importin-α/β. Cell Res (2012) 0.86
Optimisation of the two-dimensional gel electrophoresis protocol using the Taguchi approach. Proteome Sci (2004) 0.85
Cleavage of claspin by caspase-7 during apoptosis inhibits the Chk1 pathway. J Biol Chem (2005) 0.85
Control of chronic inflammation with pathway selective estrogen receptor ligands. Curr Top Med Chem (2006) 0.85
Dynamic localisation of Ran GTPase during the cell cycle. BMC Cell Biol (2009) 0.85
Phosphorylated DegU manipulates cell fate differentiation in the Bacillus subtilis biofilm. J Bacteriol (2013) 0.84
Phosphorylation of Crm1 by CDK1-cyclin-B promotes Ran-dependent mitotic spindle assembly. J Cell Sci (2013) 0.83
RNA polymerase II transcription in living color. Nat Struct Mol Biol (2007) 0.83
3-(Arylamino)-3-phenylpropan-2-olamines as a new series of dual norepinephrine and serotonin reuptake inhibitors. Bioorg Med Chem Lett (2009) 0.82
Claspin is phosphorylated in the Chk1-binding domain by a kinase distinct from Chk1. Biochem Biophys Res Commun (2008) 0.81
A mechanism coupling cell division and the control of apoptosis. SEB Exp Biol Ser (2008) 0.81
The Crm de la crème of mitosis. Nat Cell Biol (2005) 0.81
Software tools, data structures, and interfaces for microscope imaging. Cold Spring Harb Protoc (2012) 0.81
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets. Bioorg Med Chem Lett (2007) 0.80
The adenomatous polyposis coli protein contributes to normal compaction of mitotic chromatin. PLoS One (2012) 0.80
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1' substrate binding pocket. Bioorg Med Chem Lett (2007) 0.80
Synthesis and evaluation of azabicyclo[3.2.1]octane derivatives as potent mixed vasopressin antagonists. Bioorg Med Chem Lett (2010) 0.77
Quantitative analysis of digital microscope images. Methods Cell Biol (2013) 0.76
3-(Pyridin-2-yl-ethynyl)benzamide metabotropic glutamate receptor 5 negative allosteric modulators: hit to lead studies. Bioorg Med Chem Lett (2010) 0.76
Cell biology forum: Genome-wide view of mitosis. Nature (2010) 0.75
To the centre of the volcano. Workshop on the mechanisms of nucleocytoplasmic transport. EMBO Rep (2008) 0.75
Anchoring RCC1 by the tail. Nat Cell Biol (2007) 0.75