Published in Mol Cell Biol on December 17, 2007
The unnamed complex: what do we know about Smc5-Smc6? Chromosome Res (2009) 1.39
Interplay between the Smc5/6 complex and the Mph1 helicase in recombinational repair. Proc Natl Acad Sci U S A (2009) 1.31
The Smc complexes in DNA damage response. Cell Biosci (2012) 1.31
Architecture of the Smc5/6 Complex of Saccharomyces cerevisiae Reveals a Unique Interaction between the Nse5-6 Subcomplex and the Hinge Regions of Smc5 and Smc6. J Biol Chem (2009) 1.23
The Smc5/6 complex and Esc2 influence multiple replication-associated recombination processes in Saccharomyces cerevisiae. Mol Biol Cell (2010) 1.22
Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor. Nature (2016) 1.13
Nse1 RING-like domain supports functions of the Smc5-Smc6 holocomplex in genome stability. Mol Biol Cell (2008) 1.05
Structural and functional insights into the roles of the Mms21 subunit of the Smc5/6 complex. Mol Cell (2009) 1.01
Roles of vertebrate Smc5 in sister chromatid cohesion and homologous recombinational repair. Mol Cell Biol (2011) 1.01
NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity. EMBO J (2015) 1.00
Deletions flanked by breakpoints 3 and 4 on 15q13 may contribute to abnormal phenotypes. Eur J Hum Genet (2011) 1.00
The MAGE protein family and cancer. Curr Opin Cell Biol (2015) 1.00
Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance. J Clin Invest (2014) 0.98
Interactions between the Nse3 and Nse4 components of the SMC5-6 complex identify evolutionarily conserved interactions between MAGE and EID Families. PLoS One (2011) 0.94
The melanoma-associated antigen 1 (MAGEA1) protein stimulates the E3 ubiquitin-ligase activity of TRIM31 within a TRIM31-MAGEA1-NSE4 complex. Cell Cycle (2015) 0.92
Dynamic localization of SMC5/6 complex proteins during mammalian meiosis and mitosis suggests functions in distinct chromosome processes. J Cell Sci (2013) 0.90
Smc5/6-Mms21 prevents and eliminates inappropriate recombination intermediates in meiosis. PLoS Genet (2013) 0.89
Analysis of the Nse3/MAGE-binding domain of the Nse4/EID family proteins. PLoS One (2012) 0.86
Role for rodent Smc6 in pericentromeric heterochromatin domains during spermatogonial differentiation and meiosis. Cell Death Dis (2013) 0.84
The Smc5/Smc6/MAGE complex confers resistance to caffeine and genotoxic stress in Drosophila melanogaster. PLoS One (2013) 0.81
Functional interplay between cohesin and Smc5/6 complexes. Chromosoma (2014) 0.81
H2A.Z-dependent regulation of cohesin dynamics on chromosome arms. Mol Cell Biol (2014) 0.79
Purification, crystallization and preliminary X-ray crystallographic studies of the complex between Smc5 and the SUMO E3 ligase Mms21. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.79
Resolving complex chromosome structures during meiosis: versatile deployment of Smc5/6. Chromosoma (2015) 0.79
Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease. J Clin Invest (2016) 0.77
Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase. PLoS One (2014) 0.76
The Epigenetic Pathways to Ribosomal DNA Silencing. Microbiol Mol Biol Rev (2016) 0.75
A Comprehensive Guide to the MAGE Family of Ubiquitin Ligases. J Mol Biol (2017) 0.75
Molecular evolution of type II MAGE genes from ancestral MAGED2 gene and their phylogenetic resolution of basal mammalian clades. Mamm Genome (2017) 0.75
The structure and function of SMC and kleisin complexes. Annu Rev Biochem (2005) 5.38
Assigning function to yeast proteins by integration of technologies. Mol Cell (2003) 4.58
A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc Natl Acad Sci U S A (2005) 3.62
Ubc9- and mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks. Cell (2006) 3.60
Dynamic molecular linkers of the genome: the first decade of SMC proteins. Genes Dev (2005) 3.29
An overview of the MAGE gene family with the identification of all human members of the family. Cancer Res (2001) 3.08
SMC5 and SMC6 genes are required for the segregation of repetitive chromosome regions. Nat Cell Biol (2005) 2.78
The rad18 gene of Schizosaccharomyces pombe defines a new subgroup of the SMC superfamily involved in DNA repair. Mol Cell Biol (1995) 2.52
Human MMS21/NSE2 is a SUMO ligase required for DNA repair. Mol Cell Biol (2005) 2.31
Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage. Mol Cell Biol (2005) 2.16
Chromosomal association of the Smc5/6 complex reveals that it functions in differently regulated pathways. Mol Cell (2006) 2.13
Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks. EMBO J (2006) 2.13
The MAGE proteins: emerging roles in cell cycle progression, apoptosis, and neurogenetic disease. J Neurosci Res (2002) 2.00
Rad18 is required for DNA repair and checkpoint responses in fission yeast. Mol Biol Cell (1999) 1.98
Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners. Mol Cell (2003) 1.85
Novel essential DNA repair proteins Nse1 and Nse2 are subunits of the fission yeast Smc5-Smc6 complex. J Biol Chem (2003) 1.65
The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6 complex. Mol Cell Biol (2006) 1.65
Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis. Mol Biol Cell (2004) 1.52
Smc5/6 is required for repair at collapsed replication forks. Mol Cell Biol (2006) 1.51
Composition and architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) complex. Mol Cell Biol (2005) 1.50
Coordination of DNA damage responses via the Smc5/Smc6 complex. Mol Cell Biol (2004) 1.49
Identification of a novel non-structural maintenance of chromosomes (SMC) component of the SMC5-SMC6 complex involved in DNA repair. J Biol Chem (2002) 1.43
Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex. Mol Biol Cell (2001) 1.34
Rad62 protein functionally and physically associates with the smc5/smc6 protein complex and is required for chromosome integrity and recombination repair in fission yeast. Mol Cell Biol (2004) 1.30
The Smc5-Smc6 DNA repair complex. bridging of the Smc5-Smc6 heads by the KLEISIN, Nse4, and non-Kleisin subunits. J Biol Chem (2006) 1.20
Necdin-related MAGE proteins differentially interact with the E2F1 transcription factor and the p75 neurotrophin receptor. J Biol Chem (2003) 1.17
Single mage gene in the chicken genome encodes CMage, a protein with functional similarities to mammalian type II Mage proteins. Physiol Genomics (2007) 1.05
EID3 is a novel EID family member and an inhibitor of CBP-dependent co-activation. Nucleic Acids Res (2005) 1.03
Expression of Drosophila MAGE gene encoding a necdin homologous protein in postembryonic neurogenesis. Gene Expr Patterns (2006) 0.89
A necdin/MAGE-like gene in the chromosome 15 autism susceptibility region: expression, imprinting, and mapping of the human and mouse orthologues. BMC Genet (2001) 0.87
Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage. Mol Cell (2004) 6.12
Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis. Science (2005) 5.75
Y-family DNA polymerases and their role in tolerance of cellular DNA damage. Nat Rev Mol Cell Biol (2012) 3.43
Trading places: how do DNA polymerases switch during translesion DNA synthesis? Mol Cell (2005) 3.25
Structure and mechanism of human DNA polymerase eta. Nature (2010) 2.69
The Y-family DNA polymerase kappa (pol kappa) functions in mammalian nucleotide-excision repair. Nat Cell Biol (2006) 2.45
Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage. Mol Cell Biol (2005) 2.16
Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells. Mol Cell (2010) 2.09
Incidence of DNA repair deficiency disorders in western Europe: Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy. DNA Repair (Amst) (2008) 2.02
Co-localization in replication foci and interaction of human Y-family members, DNA polymerase pol eta and REVl protein. DNA Repair (Amst) (2004) 2.00
Regulation of translesion synthesis DNA polymerase eta by monoubiquitination. Mol Cell (2010) 1.84
Neurological symptoms and natural course of xeroderma pigmentosum. Brain (2008) 1.78
Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells. Proc Natl Acad Sci U S A (2008) 1.73
Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients. Proc Natl Acad Sci U S A (2002) 1.63
A role for polymerase eta in the cellular tolerance to cisplatin-induced damage. Cancer Res (2005) 1.58
Postreplication repair and PCNA modification in Schizosaccharomyces pombe. Mol Biol Cell (2006) 1.57
DNA repair: from molecular mechanism to human disease. DNA Repair (Amst) (2006) 1.56
Ubiquitination of PCNA and the polymerase switch in human cells. Cell Cycle (2004) 1.53
Role of DNA polymerase eta in the UV mutation spectrum in human cells. J Biol Chem (2003) 1.53
Malfunction of nuclease ERCC1-XPF results in diverse clinical manifestations and causes Cockayne syndrome, xeroderma pigmentosum, and Fanconi anemia. Am J Hum Genet (2013) 1.52
Composition and architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) complex. Mol Cell Biol (2005) 1.50
Reduced level of the repair/transcription factor TFIIH in trichothiodystrophy. Hum Mol Genet (2002) 1.46
Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair. Nat Genet (2012) 1.38
Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase iota. J Biol Chem (2004) 1.37
Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. EMBO J (2002) 1.36
The Bcl-2/Bcl-XL family inhibitor ABT-737 sensitizes ovarian cancer cells to carboplatin. Clin Cancer Res (2007) 1.30
Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. EMBO J (2003) 1.29
Effect of proliferating cell nuclear antigen ubiquitination and chromatin structure on the dynamic properties of the Y-family DNA polymerases. Mol Biol Cell (2008) 1.29
An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria. Cancer Cell (2006) 1.21
Two new XPD patients compound heterozygous for the same mutation demonstrate diverse clinical features. J Invest Dermatol (2005) 1.21
The Smc5-Smc6 DNA repair complex. bridging of the Smc5-Smc6 heads by the KLEISIN, Nse4, and non-Kleisin subunits. J Biol Chem (2006) 1.20
Localisation of human Y-family DNA polymerase kappa: relationship to PCNA foci. J Cell Sci (2004) 1.15
Transcription-associated breaks in xeroderma pigmentosum group D cells from patients with combined features of xeroderma pigmentosum and Cockayne syndrome. Mol Cell Biol (2005) 1.13
A semi-automated non-radioactive system for measuring recovery of RNA synthesis and unscheduled DNA synthesis using ethynyluracil derivatives. DNA Repair (Amst) (2010) 1.08
Hypomorphic PCNA mutation underlies a human DNA repair disorder. J Clin Invest (2014) 1.07
ATR-mediated phosphorylation of DNA polymerase η is needed for efficient recovery from UV damage. J Cell Biol (2011) 1.06
Human exonuclease 1 connects nucleotide excision repair (NER) processing with checkpoint activation in response to UV irradiation. Proc Natl Acad Sci U S A (2011) 1.02
Ubiquitination and deubiquitination of PCNA in response to stalling of the replication fork. Cell Cycle (2009) 1.02
DNA polymerases eta and iota. Adv Protein Chem (2004) 1.02
Interactions between the Nse3 and Nse4 components of the SMC5-6 complex identify evolutionarily conserved interactions between MAGE and EID Families. PLoS One (2011) 0.94
Maintaining integrity. Nat Cell Biol (2004) 0.94
Mutations in the C7orf11 (TTDN1) gene in six nonphotosensitive trichothiodystrophy patients: no obvious genotype-phenotype relationships. Hum Mutat (2007) 0.93
The melanoma-associated antigen 1 (MAGEA1) protein stimulates the E3 ubiquitin-ligase activity of TRIM31 within a TRIM31-MAGEA1-NSE4 complex. Cell Cycle (2015) 0.92
A role for chromatin remodellers in replication of damaged DNA. Nucleic Acids Res (2012) 0.88
SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities. DNA Repair (Amst) (2013) 0.86
Ubiquitin-binding motif of human DNA polymerase eta is required for correct localization. Proc Natl Acad Sci U S A (2009) 0.85
Ubiquitin-PCNA fusion as a mimic for mono-ubiquitinated PCNA in Schizosaccharomyces pombe. DNA Repair (Amst) (2010) 0.81
Influence of the live cell DNA marker DRAQ5 on chromatin-associated processes. DNA Repair (Amst) (2010) 0.81
DNA damage signaling and repair in Dictyostelium discoideum. Cell Cycle (2006) 0.79
Transient ectopic expression as a method to detect genes conferring drug resistance. Int J Cancer (2008) 0.79
DNA double-strand break repair pathway choice in Dictyostelium. J Cell Sci (2011) 0.78
Translesion synthesis and error-prone polymerases. Adv Exp Med Biol (2005) 0.78
Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease. J Clin Invest (2016) 0.77
A novel DNA repair disorder with thrombocytopenia, nephrosis and features overlapping Cockayne syndrome. Am J Med Genet A (2009) 0.75