Published in Traffic on December 09, 2007
Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function. Nat Rev Mol Cell Biol (2009) 4.16
Retromer. Curr Opin Cell Biol (2008) 3.89
SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors. Nat Cell Biol (2011) 2.92
A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion. Nat Cell Biol (2011) 2.68
Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7. J Cell Biol (2008) 2.56
Sorting nexins provide diversity for retromer-dependent trafficking events. Nat Cell Biol (2011) 2.32
The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network. Dev Cell (2009) 1.99
Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies. PLoS Biol (2008) 1.85
FcRn-mediated antibody transport across epithelial cells revealed by electron tomography. Nature (2008) 1.62
The early endosome: a busy sorting station for proteins at the crossroads. Histol Histopathol (2010) 1.60
SNX-BAR proteins in phosphoinositide-mediated, tubular-based endosomal sorting. Semin Cell Dev Biol (2009) 1.49
Multivesicular bodies mature from the trans-Golgi network/early endosome in Arabidopsis. Plant Cell (2011) 1.47
Retromer: a master conductor of endosome sorting. Cold Spring Harb Perspect Biol (2014) 1.46
In vitro budding of intralumenal vesicles into late endosomes is regulated by Alix and Tsg101. Mol Biol Cell (2008) 1.45
Multivesicular bodies: co-ordinated progression to maturity. Curr Opin Cell Biol (2008) 1.45
EHD3 regulates early-endosome-to-Golgi transport and preserves Golgi morphology. J Cell Sci (2009) 1.37
Evolutionary reconstruction of the retromer complex and its function in Trypanosoma brucei. J Cell Sci (2011) 1.29
Endocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families. J Biol Chem (2008) 1.26
Molecular basis for SNX-BAR-mediated assembly of distinct endosomal sorting tubules. EMBO J (2012) 1.24
Imaging and imagination: understanding the endo-lysosomal system. Histochem Cell Biol (2008) 1.21
Opposing activities of the Snx3-retromer complex and ESCRT proteins mediate regulated cargo sorting at a common endosome. Mol Biol Cell (2008) 1.21
hVps41 and VAMP7 function in direct TGN to late endosome transport of lysosomal membrane proteins. Nat Commun (2013) 1.14
Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation. J Biol Chem (2011) 1.09
Regulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8·STAM complex. J Biol Chem (2010) 1.08
Intracellular membrane traffic at high resolution. Methods Cell Biol (2010) 1.00
NRH2 is a trafficking switch to regulate sortilin localization and permit proneurotrophin-induced cell death. EMBO J (2009) 0.99
Lipid sorting and multivesicular endosome biogenesis. Cold Spring Harb Perspect Biol (2013) 0.98
BACE1 retrograde trafficking is uniquely regulated by the cytoplasmic domain of sortilin. J Biol Chem (2011) 0.98
The complex ultrastructure of the endolysosomal system. Cold Spring Harb Perspect Biol (2014) 0.97
Electron tomography of late stages of FcRn-mediated antibody transcytosis in neonatal rat small intestine. Mol Biol Cell (2012) 0.96
The HSP90 inhibitor geldanamycin perturbs endosomal structure and drives recycling ErbB2 and transferrin to modified MVBs/lysosomal compartments. Mol Biol Cell (2012) 0.91
Retromer guides STxB and CD8-M6PR from early to recycling endosomes, EHD1 guides STxB from recycling endosome to Golgi. Traffic (2012) 0.88
Retromer-Mediated Trafficking of Transmembrane Receptors and Transporters. Membranes (Basel) (2015) 0.88
Insulin responsiveness of glucose transporter 4 in 3T3-L1 cells depends on the presence of sortilin. Mol Biol Cell (2013) 0.87
Fission of SNX-BAR-coated endosomal retrograde transport carriers is promoted by the dynamin-related protein Vps1. J Cell Biol (2014) 0.87
Phosphoinositides in the mammalian endo-lysosomal network. Subcell Biochem (2012) 0.87
Precursor of brain-derived neurotrophic factor (proBDNF) forms a complex with Huntingtin-associated protein-1 (HAP1) and sortilin that modulates proBDNF trafficking, degradation, and processing. J Biol Chem (2011) 0.86
Retrograde traffic in the biosynthetic-secretory route. Histochem Cell Biol (2008) 0.85
ARF1 localizes to the golgi and the trans-golgi network. Plant Cell (2011) 0.84
Sorting nexin 1 loss results in D5 dopamine receptor dysfunction in human renal proximal tubule cells and hypertension in mice. J Biol Chem (2012) 0.84
Structure of sorting nexin 11 (SNX11) reveals a novel extended phox homology (PX) domain critical for inhibition of SNX10-induced vacuolation. J Biol Chem (2013) 0.81
Clathrin is not required for SNX-BAR-retromer-mediated carrier formation. J Cell Sci (2012) 0.81
Sorting nexins 1 and 2a locate mainly to the TGN. Protoplasma (2012) 0.80
EHDs meet the retromer: Complex regulation of retrograde transport. Cell Logist (2012) 0.79
The proneurotrophin receptor sortilin is required for Mycobacterium tuberculosis control by macrophages. Sci Rep (2016) 0.77
Trafficking of Vacuolar Sorting Receptors: New Data and New Problems. Plant Physiol (2014) 0.77
Imaging and Quantitation Techniques for Tracking Cargo along Endosome-to-Golgi Transport Pathways. Cells (2013) 0.77
Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease. PLoS One (2016) 0.76
TGN exit of the cation-independent mannose 6-phosphate receptor does not require acid hydrolase binding. Cell Logist (2014) 0.76
Rme-8 depletion perturbs Notch recycling and predisposes to pathogenic signaling. J Cell Biol (2015) 0.76
A new role under sortilin's belt in cancer. Commun Integr Biol (2016) 0.76
Ultrastructural Characterization of Membrane Rearrangements Induced by Porcine Epidemic Diarrhea Virus Infection. Viruses (2017) 0.75
TRPV3 mutants causing Olmsted Syndrome induce impaired cell adhesion and nonfunctional lysosomes. Channels (Austin) (2016) 0.75
Termination of autophagy and reformation of lysosomes regulated by mTOR. Nature (2010) 6.26
Sortilin is essential for proNGF-induced neuronal cell death. Nature (2004) 5.62
The biogenesis and functions of exosomes. Traffic (2002) 4.49
Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function. Nat Rev Mol Cell Biol (2009) 4.16
Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation. J Biol Chem (2003) 4.14
Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high- curvature membranes and 3-phosphoinositides. Curr Biol (2004) 3.76
Highly conserved protective epitopes on influenza B viruses. Science (2012) 3.47
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. J Cell Biol (2008) 3.36
Bilayered clathrin coats on endosomal vacuoles are involved in protein sorting toward lysosomes. Mol Biol Cell (2002) 3.24
Cryosectioning and immunolabeling. Nat Protoc (2007) 3.23
SNARE proteins are required for macroautophagy. Cell (2011) 2.99
An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis. J Cell Biol (2010) 2.98
Autophagy proteins regulate the secretory component of osteoclastic bone resorption. Dev Cell (2011) 2.84
Arabidopsis sterol endocytosis involves actin-mediated trafficking via ARA6-positive early endosomes. Curr Biol (2003) 2.84
Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins. J Cell Biol (2004) 2.76
Trafficking and function of the tetraspanin CD63. Exp Cell Res (2008) 2.64
Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin. Mol Biol Cell (2004) 2.60
EGFL7 regulates the collective migration of endothelial cells by restricting their spatial distribution. Development (2007) 2.45
Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex. Nat Cell Biol (2008) 2.38
Sunday Driver links axonal transport to damage signaling. J Cell Biol (2005) 2.29
Cooperation of GGAs and AP-1 in packaging MPRs at the trans-Golgi network. Science (2002) 2.28
The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport. J Cell Sci (2006) 2.12
Exit from the Golgi is required for the expansion of the autophagosomal phagophore in yeast Saccharomyces cerevisiae. Mol Biol Cell (2010) 2.10
Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury. Nat Neurosci (2007) 2.10
Secretory traffic triggers the formation of tubular continuities across Golgi sub-compartments. Nat Cell Biol (2004) 2.07
AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis. J Cell Biol (2009) 1.99
VPS10P-domain receptors - regulators of neuronal viability and function. Nat Rev Neurosci (2008) 1.98
Correlative microscopy and electron tomography of GFP through photooxidation. Nat Methods (2005) 1.97
The UIM domain of Hrs couples receptor sorting to vesicle formation. J Cell Sci (2003) 1.97
Pre- and post-Golgi translocation of glucosylceramide in glycosphingolipid synthesis. J Cell Biol (2007) 1.95
The mitochondrial contact site complex, a determinant of mitochondrial architecture. EMBO J (2011) 1.94
Short-chain ubiquitination mediates the regulated endocytosis of the aquaporin-2 water channel. Proc Natl Acad Sci U S A (2006) 1.91
Munc13-4 is an effector of rab27a and controls secretion of lysosomes in hematopoietic cells. Mol Biol Cell (2004) 1.85
The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing. EMBO Rep (2004) 1.82
A loss-of-function screen reveals SNX5 and SNX6 as potential components of the mammalian retromer. J Cell Sci (2006) 1.79
A viral protein that blocks Arf1-mediated COP-I assembly by inhibiting the guanine nucleotide exchange factor GBF1. Dev Cell (2006) 1.77
ER-to-Golgi carriers arise through direct en bloc protrusion and multistage maturation of specialized ER exit domains. Dev Cell (2003) 1.71
Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA. Mol Cell Biol (2007) 1.70
Rab14 is involved in membrane trafficking between the Golgi complex and endosomes. Mol Biol Cell (2004) 1.68
Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway. J Cell Biol (2004) 1.65
Cell division ring, a new cell division protein and vertical inheritance of a bacterial organelle in anammox planctomycetes. Mol Microbiol (2009) 1.58
Atg5-independent sequestration of ubiquitinated mycobacteria. PLoS Pathog (2009) 1.55
Opinion: The maturing role of COPI vesicles in intra-Golgi transport. Nat Rev Mol Cell Biol (2005) 1.55
mTrs130 is a component of a mammalian TRAPPII complex, a Rab1 GEF that binds to COPI-coated vesicles. Mol Biol Cell (2009) 1.55
Immuno-electron tomography of ER exit sites reveals the existence of free COPII-coated transport carriers. Nat Cell Biol (2006) 1.53
Sorting nexin 17 facilitates LRP recycling in the early endosome. EMBO J (2005) 1.50
Ligands bind to Sortilin in the tunnel of a ten-bladed beta-propeller domain. Nat Struct Mol Biol (2009) 1.50
The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding. FEBS Lett (2002) 1.48
S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover. Am J Physiol Cell Physiol (2007) 1.44
The somatodendritic endosomal regulator NEEP21 facilitates axonal targeting of L1/NgCAM. J Cell Biol (2008) 1.42
Mammalian GGAs act together to sort mannose 6-phosphate receptors. J Cell Biol (2003) 1.41
Correlative light-electron microscopy (CLEM) combining live-cell imaging and immunolabeling of ultrathin cryosections. Nat Methods (2008) 1.40
Electron tomography of early melanosomes: implications for melanogenesis and the generation of fibrillar amyloid sheets. Proc Natl Acad Sci U S A (2008) 1.40
Rabaptin-5alpha/rabaptin-4 serves as a linker between rab4 and gamma(1)-adaptin in membrane recycling from endosomes. EMBO J (2003) 1.39
Sorting nexin-2 is associated with tubular elements of the early endosome, but is not essential for retromer-mediated endosome-to-TGN transport. J Cell Sci (2005) 1.38
Phosphorylation of a membrane curvature-sensing motif switches function of the HOPS subunit Vps41 in membrane tethering. J Cell Biol (2010) 1.34
Immunoelectron microscopic localization of cholesterol using biotinylated and non-cytolytic perfringolysin O. J Histochem Cytochem (2002) 1.33
Electron microscopy in cell biology: integrating structure and function. Nat Rev Mol Cell Biol (2003) 1.33
Glycosylation is important for cell surface expression of the water channel aquaporin-2 but is not essential for tetramerization in the endoplasmic reticulum. J Biol Chem (2003) 1.32
Universal cardiac induction of human pluripotent stem cells in two and three-dimensional formats: implications for in vitro maturation. Stem Cells (2015) 1.27
The annexin 2/S100A10 complex controls the distribution of transferrin receptor-containing recycling endosomes. Mol Biol Cell (2003) 1.27
Peroxisomes start their life in the endoplasmic reticulum. Traffic (2003) 1.26
Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity. Proc Natl Acad Sci U S A (2009) 1.24
The metalloprotease disintegrin ADAM8. Processing by autocatalysis is required for proteolytic activity and cell adhesion. J Biol Chem (2002) 1.23
The CORVET subunit Vps8 cooperates with the Rab5 homolog Vps21 to induce clustering of late endosomal compartments. Mol Biol Cell (2009) 1.23
ATPase-deficient hVPS4 impairs formation of internal endosomal vesicles and stabilizes bilayered clathrin coats on endosomal vacuoles. J Cell Sci (2004) 1.22
Imaging and imagination: understanding the endo-lysosomal system. Histochem Cell Biol (2008) 1.21
Identification of a clonally expanding haematopoietic compartment in bone marrow. EMBO J (2012) 1.19
Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes. PLoS Biol (2010) 1.18
Death-receptor activation halts clathrin-dependent endocytosis. Proc Natl Acad Sci U S A (2006) 1.18
Linking ultrastructure and function in four genera of anaerobic ammonium-oxidizing bacteria: cell plan, glycogen storage, and localization of cytochrome C proteins. J Bacteriol (2007) 1.18
CD99 and CD99L2 act at the same site as, but independently of, PECAM-1 during leukocyte diapedesis. Blood (2010) 1.16
Receptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry disease. PLoS One (2011) 1.15
Endosomes: multipurpose designs for integrating housekeeping and specialized tasks. Histochem Cell Biol (2001) 1.15
In vivo role of lipid adducts on Wingless. J Cell Sci (2008) 1.14
hVps41 and VAMP7 function in direct TGN to late endosome transport of lysosomal membrane proteins. Nat Commun (2013) 1.14
Egfl7 knockdown causes defects in the extension and junctional arrangements of endothelial cells during zebrafish vasculogenesis. Dev Dyn (2008) 1.13
The plasticity of multivesicular bodies and the regulation of antigen presentation. Semin Cell Dev Biol (2002) 1.12
Combined structural and chemical analysis of the anammoxosome: a membrane-bounded intracytoplasmic compartment in anammox bacteria. J Struct Biol (2007) 1.12
The RapGEF PDZ-GEF2 is required for maturation of cell-cell junctions. Cell Signal (2008) 1.11
Smed-SmB, a member of the LSm protein superfamily, is essential for chromatoid body organization and planarian stem cell proliferation. Development (2010) 1.10
Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous system. J Comp Neurol (2003) 1.10
Regulation of P2Y1 receptor traffic by sorting Nexin 1 is retromer independent. Traffic (2010) 1.09
Involvement of a Golgi-resident GPI-anchored protein in maintenance of the Golgi structure. Mol Biol Cell (2007) 1.09
Cripto recruits Furin and PACE4 and controls Nodal trafficking during proteolytic maturation. EMBO J (2008) 1.09
Presenilin-1 exists in both pre- and post-Golgi compartments and recycles via COPI-coated membranes. Traffic (2003) 1.08
Template matching as a tool for annotation of tomograms of stained biological structures. J Struct Biol (2006) 1.07
CD208/dendritic cell-lysosomal associated membrane protein is a marker of normal and transformed type II pneumocytes. Am J Pathol (2004) 1.06
MHC class II compartments in human dendritic cells undergo profound structural changes upon activation. Traffic (2002) 1.06
The suppression of brain cold-stable microtubules in mice induces synaptic defects associated with neuroleptic-sensitive behavioral disorders. Genes Dev (2002) 1.06
Annexin A8 regulates late endosome organization and function. Mol Biol Cell (2008) 1.03
A flippase-independent function of ATP8B1, the protein affected in familial intrahepatic cholestasis type 1, is required for apical protein expression and microvillus formation in polarized epithelial cells. Hepatology (2010) 1.03
Golgi enzymes are enriched in perforated zones of golgi cisternae but are depleted in COPI vesicles. Mol Biol Cell (2004) 1.03
Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1. Proc Natl Acad Sci U S A (2009) 1.02
The yeast Vps10p cytoplasmic tail mediates lysosomal sorting in mammalian cells and interacts with human GGAs. J Biol Chem (2002) 1.01
Associations among genotype, clinical phenotype, and intracellular localization of trafficking proteins in ARC syndrome. Hum Mutat (2012) 1.00